[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Journal Information::
Articles archive::
For Authors::
For Reviewers::
Contact us::
Site Facilities::
Indexing & Abstracting::
Publication Ethics::
Search in website

Advanced Search
Receive site information
Enter your Email in the following box to receive the site news and information.
Indexing & Abstracting
:: Volume 24, Issue 3 And ضمیمه1 (7-2019) ::
__Armaghane Danesh__ 2019, 24(3 And ضمیمه1): 484-495 Back to browse issues page
Changes in Orexin A Serum Level, Insulin Resistance and Anthropometric Indices in Overweight Women after Six Weeks of Aerobic Training
G Taheri1 , M Fathi 2, E Mir3
1- Department of Sport Physiology, Bojnourd Branch, Islamic Azad University, Bojnourd, Ira
2- Department of Sport Physiology, Ferdowsi University of Mashhad, Mashhad, Iran , ehsanmir90@yahoo.com
3- Department of Sport Physiology, Ferdowsi University of Mashhad, Mashhad, Iran
Abstract:   (4113 Views)
1.Oliveira A, Monteiro A, Jácome C, Afreixo V, Marques A. Effects of group sports on health-related physical fitness of overweight youth: a systematic review and meta-analysis. Scandinavian Journal Of Medicine & Science In Sports 2017; 27(6): 604-11.##
2.Bray GA. Fructose: should we worry? International Journal of Obesity 2009; 32(S7): S127. ##
3.Bilski J, Teległów A, Zahradnik-bilska J, Dembiński A, Warzecha Z. Effects of exercise on appetite and food intake regulation. Medicina Sportiva 2009; 13(2): 82-94. ##
4.Shabani M, Mohammad-Zadeh M, Azhdari-Zarmehri H. Orexin (hypocretin): a multi-functional hypothalamic peptide. Koomesh 2014;15(3): 275-81. ##
5.Sakurai T, Amemiya A, Ishii M, Matsuzaki I, Chemelli RM, Tanaka H, et al. Orexins and orexin receptors: a family of hypothalamic neuropeptides and g protein-coupled receptors that regulate feeding behavior. Cell 1998; 92(4): 573-85. ##
6.Coleman DL. Obese and diabetes: two mutant genes causing diabetes-obesity syndromes in mice. Diabetologia 1978; 14(3): 141-8. ##
7.Kirchgessner AL. Orexins in the brain-gut axis. Endocrine Reviews 2002; 23(1): 1-15. ##
8.Chemelli RM, Willie JT, Sinton CM, Elmquist JK, scammell T, lee C, et al. Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation. Cell 1999; 98(4): 437-51. ##
9.Salehi Omran MT, Jafari S. Association of admission insulin resistance index with early cardiac complications in non diabetic patients with acute coronary syndrome. Journal of Babol University of Medical Sciences(Jbums) 2009; 6(47): 62-6. ##
10.Defronzo RA. Pathogenesis of type 2 diabetes mellitus. Medical clinics 2004; 88(4): 787-835. ##
11.Skrzypski M, le T, Kaczmarek P, Pruszynska-Oszmalek E, Pietrzak P, Szczepankiewicz D, et al. Orexin a stimulates glucose uptake, lipid accumulation and adiponectin secretion from 3t3-l1 adipocytes and isolated primary rat adipocytes. Diabetologia 2011; 54(7): 1841-52. ##
12.Miyasaka K, Masuda M, Kanai S, Sato N, Kurosawa M, Funakoshi A. Central orexin-a stimulates pancreatic exocrine secretion via the vagus. Pancreas 2002; 25(4): 400-4. ##
13.Matsumura K, Tsuchihashi T, Abe I. Central orexin-a augments sympathoadrenal outflow in conscious rabbits. Hypertension 2001; 37(6): 1382-7. ##
14.Martynska l, Wolinska-witort E, Chmielowska M, Bik W, Baranowska B. The physiological role of orexins. Neuro Endocrinology Letters 2005; 26(4): 289-92. ##
15.Abaassi daluee A, Ghanbari niaki A, Fathi R, Hedayati M. The effect of a single session aerobic exercise on plasma ghrelin, gh, insulin and cortisol in non-athlete university male students. Iranian Journal of Endocrinology and Metabolism 2011; 13(2): 197-201. ##
16.Bagheri Nia M, Abedi B. Effect of eight weeks of pilates training on orexin and insulin resistance levels in overweight children. Yafteh 2018; 1(75): E00109. ##
17.Haskell-luevano C, Schaub JW, Andreasen A, Haskell KR, Moore MC, Koerper IM, et al. Voluntary exercise prevents the obese and diabetic metabolic syndrome of the melanocortin-4 receptor knockout mouse. The Faseb Journal 2009; 23(2): 642-55. ##
18.Mir E, Fathei M, Sayeedi MM, Hejazi K. The effect of eight weeks combined training (aerobic-resistance) on homocysteine, c-reactive protein and lipid profile in inactive elderly men. Medical Journal of Tabriz University of Medical Sciences & Health Services 2015; 36(6): 80-6. ##
19.Abdolmaleki Z, Saleh SB, Bahram A, Abdolmaleki F. Validity and reliability of the physical self-description questionnaire among adolescent girls. Journal of Applied Psychology 2011; 4(16):               42-55. ##
20.Bonora E, Formentini G, Calcaterra F, Lombardi S, Marini F, Zenari L, et al. Homa-estimated insulin resistance is an independent predictor of cardiovascular disease in type 2 diabetic subjects: prospective data from the verona diabetes complications study. Diabetes Care 2002; 25(7):            1135-41. ##
21.Alizadeh AA, Rahmani-nia F, Mohebbi H, Zakerkish M. Effects of eight weeks aerobic exercise on plasma levels of orexin a, leptin, glucose, insulin, and insulin resistance in males with type 2 diabetes. Iranian Journal of Diabetes and Obesity 2015; 7(2): 62-8. ##
22.James MH, Campbell EJ, walker FR, Smith DW, Richardson HN, Hodgson DM, et al. Exercise reverses the effects of early life stress on orexin cell reactivity in male but not female rats. Frontiers in Behavioral Neuroscience 2014; 8: 244. . ##
23.Wu H, Xia FZ, Xu H, Zhai H, Zhang MF, Zhang HX, et al. Acute effects of different glycemic index diets on serum motilin, orexin and neuropeptide y concentrations in healthy individuals. Neuropeptides 2012; 46(3): 113-8. . ##
24.Ouedraogo R, Näslund E, Kirchgessner AL. Glucose regulates the release of orexin-a from the endocrine pancreas. Diabetes 2003; 52(1): 111-7. . ##
25.Wu T, Gao X, Chen M, Van Dam R. Long-term effectiveness of diet-plus-exercise interventions vs. Diet-only interventions for weight loss: a meta-analysis. Obesity Reviews 2009; 10(3): 313-23. . ##
26.O'neill HM. Ampk and exercise: glucose uptake and insulin sensitivity. Diabetes & metabolism Journal 2013; 37(1): 1-21. . ##
27.Messina G, Di bernardo G, Messina A, Dalia C, Chieffi S, Galderisi U, et al. Brief exercise enhances blood hypocretin-1 in sedentary men. Journal of Sports Medicine & Doping Studies 2014; 4: 149. . ##
28.Butterick TA, Billington CJ, Kotz CM, Nixon JP. Orexin: pathways to obesity resistance? Reviews in Endocrine and Metabolic Disorders 2013; 14(4): 357-64. . ##
29.Sundarrajan L, Unniappan S. Small interfering RNA mediated knockdown of irisin suppresses food intake and modulates appetite regulatory peptides in zebrafish. General and comparative endocrinology. 2017;252:200-8. . ##
30.Bijeh N, Hejazi K. The effect of aerobic exercise on levels of HS-CRP, insulin resistance index and lipid profile in untrained middle-aged women. Razi Journal of Medical Sciences. 2018 Jan 15;24(10):1-1. . ##
31.Ho SS, Dhaliwal SS, Hills AP, Pal S. The effect of 12 weeks of aerobic, resistance or combination exercise training on cardiovascular risk factors in the overweight and obese in a randomized trial. Bmc Public Health 2012; 12(1): 704. . ##
32.Saremi A, Shavandi N, Mohammadpour K. Effects of 8 weeks aerobic training with omega-3 supplementation on inflammatory responses in type 2 diabetic patients. Payesh 2015; 14: 1. . ##
33.Oki K, Yamane K, Kamei N, Nojima H, Kohno N. Circulating visfatin level is correlated with inflammation, but not with insulin resistance. Clinical Endocrinology 2007; 67(5): 796-800. . ##
34.Smith JK, Dykes R, Douglas JE, Krishnaswamy G, Berk S. Long-term exercise and atherogenic activity of blood mononuclear cells in persons at risk of developing ischemic heart disease. Jama 1999; 281(18): 1722-7. . ##
35.Church TS, Barlow CE, Earnest CP, Kampert JB, Priest EL, Blair SN. Associations between cardiorespiratory fitness and c-reactive protein in men. Arteriosclerosis, Thrombosis, and Vascular Biology 2002; 22(11): 1869-76. . ##
36.Christopherson J, Sumer V, Kirkendall D, Jones MA. Effects of exercise detraining on lipid storage in rats. Transactions of the Iillinois State Academy of Science 1999; 92(3): 203-9.
37.Kodama S, Miao S, Yamada N, Sone H. Exercise training for ameliorating cardiovascular risk factors-focusing on exercise intensity and amount. International Journal of Sport and Health Science 2006; 4(2): 325-38. . ##
38.Hosseini k, Attarnejad Z, hosseini HA. A comparison of the effects of two aquatic exercise sessions with different duration on adiponectin and insulin resistance in women with type 2 diabetes. Journal of Sabzevar University of Medical Sciences 2014; 20: 4. . ##
39.Kadoglou NP, Vrabas IS, Kapelouzou A, Lampropoulos S, Sailer N, Kostakis A, et al. The impact of aerobic exercise training on novel adipokines, apelin and ghrelin, in patients with type 2 diabetes. Medical Science Monitor: International Medical Journal of Experimental and Clinical Research 2012; 18(5): cr290. . ##
Armaghane-danesh, Yasuj University of                                                                                   Original Article


Medical Sciences Journal (YUMSJ)
Changes in Orexin A Serum Level, Insulin Resistance and Anthropometric Indices in Overweight Women after Six Weeks of Aerobic Training
Taheri G1, Fathi M2*, Mir E2
[1]Department of Sport Physiology, Bojnourd Branch, Islamic Azad University, Bojnourd, Iran, 2 Department of Sport Physiology, Ferdowsi University of Mashhad, Mashhad, Iran
Received: 10 Dec 2018          Accepted: 12 May 2019
Background & aim: Orexin is an orexigenic peptide present in the form of A and B in the blood. Orexin neurons respond to a number of metabolic signals that indicate the body's energy status. The present study was carried out to evaluate the effect of six weeks of aerobic training on orexin level, insulin resistance and anthropometric indices in overweight women.
Methods: In the present quasi-experimental study, the statistical population consisted of overweight and inactive women in Bojnourd, Iran,, aged 45-65 years, and BMI 26-29 kg/m2. Twenty-four eligible individuals were randomly divided into two groups of control and exercise. The exercise included aerobic training (with intensity of 60-70% of maximum heart rate reserve). The exercise performed three times per week for six weeks.
Results: The six weeks of aerobic training increased the orexin A level and decreased insulin, glucose, insulin resistance index, weight, BMI, WHR and fat percentage in interventional group. But in control group none of these variables changed significantly after six weeks(P<0.05).
Conclusion: The six weeks of aerobic training increased the orexin A level, decreased insulin resistance and improves anthropometric indices in overweight women. Therefore, obese women are recommended to use these exercises as a preventive method for future diabetes and cardiovascular diseases.
Keywords: Orxin, Insulin Resistance, Exercise
Full-Text [PDF 149 kb]   (607 Downloads)    
Type of Study: Research | Subject: Sport Physiology
Received: 2018/12/10 | Accepted: 2019/04/22 | Published: 2019/07/7
Send email to the article author

Add your comments about this article
Your username or Email:


XML   Persian Abstract   Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Taheri G, Fathi M, Mir E. Changes in Orexin A Serum Level, Insulin Resistance and Anthropometric Indices in Overweight Women after Six Weeks of Aerobic Training. armaghanj 2019; 24 (3) :484-495
URL: http://armaghanj.yums.ac.ir/article-1-2370-en.html

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 24, Issue 3 And ضمیمه1 (7-2019) Back to browse issues page
ارمغان دانش Armaghane Danesh
Persian site map - English site map - Created in 0.05 seconds with 39 queries by YEKTAWEB 4652