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:: Volume 17, Issue 2 (6-2012) ::
__Armaghane Danesh__ 2012, 17(2): 149-155 Back to browse issues page
Effect of Aloe Vera Extract on Testicular Tissue of Embryo of Diabetic Rats
M Jafari Barmak , Z Khaksar 1
1- , Khaksar@shirazu.ac.ir
Abstract:   (2130 Views)
Background & aim: Testis is an important organ of the male reproductive system and its structure could be influenced by diabetes. Aloe Vera has a hypoglycemic effect thus, the present study evaluates the effect of Aloe Vera on the testis tissue of a 20-day embryo of rat born from a diabetic mother. Methods: Thirty female Sprague Dawley rats were randomly divided into three groups, subsequently two groups were injected with streptozotocin (50 mg/kg/IP) and the males were placed next to female rats in a separate cage in order to mate. One group of rats received aloe vera extract (400 mg/kg), orally, in gestational age during while others were giving distilled water. After 20 days, rats were sacrificed and their embryos were removed and fixed by 10% formalin. The embryos were processed and embeded in paraffin. Five µm sections were made and stained by hematoxyline- eosin and cellular alteration of testis was evaluated. Data were analyzed using one-way ANOVA. Results: Mean of body weight, seminiferous tubules diameter, spermatogonia numbers, leydig cells and sertoli cells were significantly different in all groups (p<0.05). Conclusion: The present study demonstrated that Aloe Vera extract can increase the spermatogonium, Leydig and Sertoli cells in diabetic rats.
Keywords: Aloe vera, Testis, Diabetes.
Full-Text [PDF 800 kb]   (815 Downloads)    
Type of Study: Research | Subject: Special
Received: 2015/04/26 | Accepted: 2015/04/26 | Published: 2015/04/26
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Jafari Barmak M, khaksar Z. Effect of Aloe Vera Extract on Testicular Tissue of Embryo of Diabetic Rats. Armaghane danesh. 2012; 17 (2) :149-155
URL: http://armaghanj.yums.ac.ir/article-1-302-en.html

Volume 17, Issue 2 (6-2012) Back to browse issues page
ارمغان دانش Armaghane danesh
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