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:: Volume 29, Issue 2 (2-2024) ::
__Armaghane Danesh__ 2024, 29(2): 0-0 Back to browse issues page
The effect of the covid-19 epidemic on the prevalence of opportunistic fungal infections and the consumption of antifungal drugs in patients hospitalized in Abadan hospitals
Hoda Mojiri-Forushani 1, Atefeh Zahedi2 , Mohammad Imani3
1- Abadan University of Medical Sciences , dr.mojiri@yahoo.com
2- Asadabad School of Medical Sciences
3- Abadan University of Medical Sciences
Abstract:   (217 Views)
Background and Objective: Following COVID-19, secondary fungal infections are a severe issue. Antifungal medications are also used to treat people who have fungal infections. This study aimed the prevalance of fungi infections and the usage of antifungal medications before and after the COVID-19 pandemic.

Research and method: This study's research design is descriptive, analytical, and retrospective. The records of patients who were hospitalized in Abadan hospitals in the year before or the first two years of the COVID-19 pandemic and received at least one of the antifungal medication’s fluconazole, caspofungin, or amphotericin B were extracted and assessed for this study. The frequency, mean, chi-square, and ANOVA descriptive statistics were employed to examine the data.

Findings:  The results showed that, the of mucormycosis and aspergillus fungal infections has dramatically increased in the two years since the COVID-19 pandemic. Although it was not statistically significant, the usage of antifungal medications rose in the two years following the beginning of COVID-19 compared to the two years prior. The mucormycosis fungus is the most prevalent fungal infection. The lung was the most commonly infected organ. All patients with fungal infection, had a history of severe COVID-19 following the COVID-19 pandemic. The most often used medication is amphotericin B. This difference was substantial (P< 0.001) when aspergillosis patients received capsofungin, mucormycosis patients received amphotericin B, and candida patients received fluconazole

Discussion: This study demonstrated that aspergillosis and mucormycosis fungal infections have become more common during the COVID-19 pandemic, and as a result, antifungal medication use has increased as well. Additionally, all three medications (fluconazole, caspofungin, and amphotericin B) were administrated according guidelines
Keywords: Amphotericin B, Caspofungin, Fluconazole, COVID-19, opportunistic infection.
     
Type of Study: Research | Subject: Infectious Disease
Received: 2023/10/8 | Accepted: 2024/03/16 | Published: 2024/03/16
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Mojiri-Forushani H, Zahedi A, Imani M. The effect of the covid-19 epidemic on the prevalence of opportunistic fungal infections and the consumption of antifungal drugs in patients hospitalized in Abadan hospitals. armaghanj 2024; 29 (2)
URL: http://armaghanj.yums.ac.ir/article-1-3532-en.html


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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 29, Issue 2 (2-2024) Back to browse issues page
ارمغان دانش Armaghane Danesh
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