Evaluation of Frequency Bacterial Meningitis Causes with Febrile Seizures in Children Under Five years at Imam Sajjad Hospital

Mohammadi , B; Ghadimi Moghadam,  AK; Mohammadi,  N; Mohammadi , J

doi:10.61186/armaghanj.29.4.583

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Volume 29, Issue 4 (7-2024)

__Armaghane Danesh__ 2024, 29(4): 583-596

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Evaluation of Frequency Bacterial Meningitis Causes with Febrile Seizures in Children Under Five years at Imam Sajjad Hospital

B Mohammadi

¹, AK Ghadimi Moghadam²

, N Mohammadi³

, J Mohammadi⁴

1- Department of Pediatrics, Yasuj University of Medical Sciences, Yasuj, Iran , jamshidm2005@yahoo.com
2- Department of Pediatrics, Yasuj University of Medical Sciences, Yasuj, Iran
3- Yasuj University of Medical Sciences, Yasuj, Iran
4- Department of Physiology and Pharmacology, Yasuj University of Medical Sciences, Yasuj, Iran.

Abstract: (589 Views)

Background & aim: Febrile seizure is one of the most common neurological diseases in children, which occurs in 3-5% of children aged 6 months to 5 years. This type of seizure, which is the most common form of seizure in children, is usually harmless and does not increase the risk of non-febrile seizures. Therefore, the aim of the present study was to determine and investigate the frequency of bacterial meningitis in febrile convulsions in children under five years of age at Imam Sajad Hospital in Yasuj, Iran, from 2018 to 2020.

Methods: In the present descriptive-analytical study conducted in the pediatric department of Imam Sajad Hospital of Yasuj, Iran, the total number of febrile convulsion patients in children under five years of age admitted to the pediatric department between 2018 and 2020 was determined and by examining the information recorded in the medical record of each patient, the items mentioned in the questionnaire form were completed. The questionnaire included personal-social and background information of patients such as age, gender, underlying disease, seizure history, neurological symptoms including; Neck stiffness, Kerning and Brodzinski, clinical symptoms include headache and vomiting and treatment.
The collected data were analyzed using chi-square and descriptive statistical tests, including frequency and mean.

Results: Out of 296 children under five years of age with fever-convulsions in the study according to gender, 121 were girls and 175 were boys. There was no significant difference between patients diagnosed with bacterial meningitis and other patients according to gender. Moreover, no significant relationship was observed for the variables of age, vomiting and lethargy. In the analysis of the obtained results, the symptoms of headache, Kerning, Brodzinski, neck stiffness and type of seizure had a significant relationship with bacterial meningitis compared to other patients suspected of having meningitis (p<0.05). Comparing the distribution of fever-seizure patients according to the frequency of LP and positive CSF cases indicated that there was a significant difference between patients diagnosed with bacterial meningitis and other patients (p value = 0.000).

Conclusion: no positive sample of bacterial culture was observed and the diagnosis was based on the clinical judgment of the physician and CSF analysis. A number of clinical symptoms were significantly related to the cases diagnosed as bacterial meningitis, and these clinical findings can be used for a more accurate diagnosis of bacterial meningitis. Though these patients were not significantly different from other patients in terms of demographic factors, these indicators can help in better diagnosis of bacterial meningitis in Yasuj patients.

Keywords: Bacterial meningitis, Kerning, Brudzinski, Febrile seizures, LP, CSF

Full-Text [PDF 985 kb] (62 Downloads)

Type of Study: Research | Subject: Clinical
Received: 2023/10/4 | Accepted: 2024/05/21 | Published: 2024/08/3

References

1. Commission on epidemiology and prognosis, international league against epilepsy. Guidelines for epidemiologic studies on epilepsy. Raven press, LTd., New York. Epilepsia 1993; 34: 592-8.## [DOI:10.1111/j.1528-1157.1993.tb00433.x]

2. International league against epilepsy. Commission on epidemiology and prognosis, international league against epilepsy. Guidelines for epidemiologic studies on epilepsy. Raven press Ltd: New York, Epilepsia; 1993; 592-8.## [DOI:10.1111/j.1528-1157.1993.tb00433.x]

3. Kliegman RM, Stanton BF, Schor NF, Berman RE. Nelson textbook of pediatrics. 19th ed. Philadelphia: Elsevier Saunders; 2011; 751-9.##

4. Hauser S, Josephsin S. Harrison s neurology in Clinical medicine. 3rd ed. New York: Mc Graw Hil; 2012; 752.##

5. Sattar S, Saha SK, Parveen F, Banu LA, Momen A, Ahmed AU, et al. Intermittent prophylaxis of recurrent febrile seizures with clobazam versus diazepam. Mymensingh Med J 2014; 23(4): 676-85.##

6. Shiva F, Hashemian HR. Febrile seizures: Clinical course and diagnostic evaluation. J Pak Med Assoc 1998; 48(9): 276-7.##

7. Subcommittee on febrile seizures; american academy of pediatrics. Neurodiagnostic evaluation of the child with a simple febrile seizure. Pediatrics 2011; 127(2): 389-94.## [DOI:10.1542/peds.2010-3318]

8. Kenneth B, Roberts MD. Urinary tract infection: clinical practice guideline for the diagnosis and management of the initial uti in febrile infants and children 2 to 24 months. Pediatrics 2011; 128(3): 595-610. ## [DOI:10.1542/peds.2011-1330]

9. Jaskiewicz JA, McCarthy CA, Richardson AC, White KC, Fisher DJ, Dagan R, et al. Febrile infants at low risk for serious bacterial infection--an appraisal of the Rochester criteria and implications for management. Febrile infant collaborative study group. Pediatrics 1994; 94(3): 390-6.## [DOI:10.1542/peds.94.3.390]

10. Karimi A, Fahimzad SA, Mansour Ghanaie R. Management of a child with decreased level of consciousness. Arch Pediatr Infect Dis 2013; 1(2): 92-101.## [DOI:10.5812/pedinfect.9135]

11. Mel'nikova EV, Shchekina OG, Borisova MN, Denisova LB, Baranova IN. Characteristics of the strategy of intensive care of unconscious children. Anesteziol Reanimatol 2000; 1: 36-8.##

12. Ben Hamouda H, Ben Haj khalifa A, Hamza MA, Ayadi A, Soua H, Khedher M, et al. Clinical outcome and prognosis of neonatal bacterial meningitis. Arch Pediatr 2013; 20: 938-44. ## [DOI:10.1016/j.arcped.2013.05.005]

13. Kliegman RM, Behrman RE, Jenson HB, Stanton BMD. Nelson textbook of pediatrics. 18th ed. Philadelphia: Saunders; 2007; 2457-58.##

14. Sanaei Dashty A, Akhlaghi AK, Pazoki R. Clinical risk factors of febrile seizure in children in a university hospital in Bushehr port. Iran South Med J 2007; 9(2): 168-74.##

15. Dubos F, De la Rocque F, Levy C, Bingen E, Aujard Y, Cohen R, et al. Bacterial meningitis study group. Sensitivity of the bacterial meningitis score in 889 children with bacterial meningitis. The Journal of pediatrics 2008;152(3): 378-82.## [DOI:10.1016/j.jpeds.2007.07.012]

16. Nasiri J, Mokhtarian F. Incidence of meningitis in children aged 6-18 months with first febrile seizure and good general condition referring to imam hossein and amin hospitals, isfahan, iran, from may 2016 to march 2017. J Isfahan Med Sch 2018; 35(455): 1633-9.##

17. Ehsanipour F, Khodapanahandeh F, Aslani Z. The prevalence of meningitis in children with febrile seizure hospitalized at hazrat rasoul hospital (1997-2002). RJMS 2005; 11(44): 907-11.##

18. Eldardear A, Alhejaili FAD, Alharbi AMD, Alrehaili FSS, Mohammed KTA, Binladin AKA, et al. Incidence of Meningitis in patients presenting with febrile seizures. Cureus 2020; 12(12): e11941.## [DOI:10.7759/cureus.11941]

19. Ghadimi Moghaddam A, Ghatee MA, Keshtkari A, Shabankare M. Prevalence of bacterial causes of meningitis and related factors in patients admitted to Imam Sajjad Hospital in Yasuj. Armaghane-danesh 2020; 24(5): 853-64.##

20. Khodapanahandeh F, Ramzi D. Evaluation of status epilepticus in patients admitted to the pediatric intensive care unit of rasool akram hospital. RJMS 2007; 14(56): 101-8.##

21. Vestergaard M, Hviid A, Madsen KM, Wohlfahrt J, Thorsen P, Schendel D, et al. MMR vaccination and febrile seizures-Evaluation of susceptible subgroups and long-term prognosis. JAMA 2004; 292(3): 351-7.## [DOI:10.1001/jama.292.3.351]

22. Jarousha AM, Al afifi A. Epidemiology and risk factors associated with developing bacterial meningitis among children in gaza strip. Iran J Public Health 2014; 43(9): 1176-83.##

23. Naghavi M, Sobhani A, Kharazi H. Recurrence of attack and associated factors in children with febrile convulsion admitted in hospital. Jour Guilan Uni Med Sci 2000; 9(35 and 36) :22-7.##

24. Abbaskhanian A, Rezai M S, Ghafarri J, Abbaskhani Davanloo A. Study of demographic and etiologic first attack of febrile seizure in children. J Mazandaran Univ Med Sci 2012; 22(94): 36-42.##

25. Moghadam AG, Yousefi E, Ghatie MA, Moghadam AG, Pouladfar GR, Jamalidoust M. Investigating the etiologic agents of aseptic meningitis outbreak in Iranian children. J Family Med Prim Care 2020; 9: 1573-7. [DOI:10.4103/jfmpc.jfmpc_1003_19]

26. Leung AK. Febrile seizures. J Pediatr Health Care 2007; 21(4): 250-5. ## [DOI:10.1016/j.pedhc.2006.10.006]

27. Pal DK, Kugler SL, Mandelbaum DE, Durner M. Phenotypic features of familial febrile seizures: case-control study. Neurology 2003; 60: 410-4.## [DOI:10.1212/WNL.60.3.410]

28. Braunwald E, Fauci AS, Kasper DL, Hauser SL, Longo DL, Jameson JL. Harrison's principles of internal medicine 15th ed. New York: McGraw-Hill; 2001, 2462-71.##

29. Sartori S, Nosadini M, Tessarin G, Boniver C, Frigo AC, Toldo I, et al. First-ever convulsive seizures in children presenting to the emergency department: Risk factors for seizure recurrence and diagnosis of epilepsy. Dev Med Child Neurol 2019; 61: 82-90. ## [DOI:10.1111/dmcn.14015]

30. Kimia A, Ben-Joseph EP, Rudloe T, Capraro A, Sarco D, Hummel D, et al. Yield of lumbar puncture among children who present with their first complex febrile seizure. Pediatrics 2010; 126: 62-69.## [DOI:10.1542/peds.2009-2741]

31. Sargazi A, Bagheri S, Hajirezaei H, Rashidi O, Ataran A. Prevalence of bacterial meningitis in children with apparent febrile convulsion. Int J Pediatr 2022; 10 (11): 17014-19. ##

32. Tavasoli A, Afsharkhas L, Edraki A. Frequency of meningitis in children presenting with febrile seizure in ali- asghar children's hospital. Iran J Child Neurol 2014; 8(4): 51-6.##

33. Eldardear A, Alhejaili FAD, Alharbi AMD, Alrehaili FSS, Mohammed KTA, Binladin AKA, et al. Incidence of meningitis in patients presenting with febrile seizures. Cureus 2020; 12(12): e11941.## [DOI:10.7759/cureus.11941]

34. Okubo Y, Hayakawa I, Nariai H, Michihata N, Matsui H, Fushimi K, Yasunaga H. Recent practice patterns in diagnostic procedures anticonvulsants, and antibiotics for children hospitalized with febrile seizure. Seizure 2019; 67: 52-6.## [DOI:10.1016/j.seizure.2019.03.007]

35. Lee J, DeLaroche AM, Janke AT, Kannikeswaran N, Levy PD. Complex febrile seizures, lumbar puncture, and central nervous system infections: a national perspective. Acad Emerg Med 2018; 25(11): 1242-50.## [DOI:10.1111/acem.13441]

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Mohammadi B, Ghadimi Moghadam A, Mohammadi N, Mohammadi J. Evaluation of Frequency Bacterial Meningitis Causes with Febrile Seizures in Children Under Five years at Imam Sajjad Hospital. armaghanj 2024; 29 (4) :583-596
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