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Effect of Oral Clonidine onPost Operative Nausea andVomiting in GynecologicalLaparoscopic Surgery
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F Javaherforoosh   , M Pipelzadeh , M Namazi |
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Abstract: (3519 Views) |
| Introduction & Objective: Despite advances in anesthesia
nausea and vomiting is still a frequent post operative complication
of general anesthesia for laparoscopic surgery. Many treatment
modalities have been tried to reduce this unpleasant side effect. In
this study we assessed the efficacy of oral clonidine in
laparoscopic surgery in gynecological laparoscopic surgery.
Materials & Methods: In this prospective double blind study, 86
ASA classes 1 or 2 were selected. Study group (n=43) received
clonidine (0.2 mg tablet with 50 cc water) 60 – 90 minutes before
surgery while control group ( n=43) received placebo. The patients
were monitored for presence of nausea and vomiting for 24 hours.
Moreover sedation scores and hemodynamic changes between 2
groups were compared. Collected data were analyzed by SPSS
using chi–square and Fisher tests.
Results: Nine patients (20.9%) in study group and 19 patients
(44.2%) in control group nauseated (p = 0.0 21) while 16.3% of
patients in study group and 34.9% in control group vomited (p =
0.048).
Conclusion: Clonidine had statistically significant effect on
reducing the incidence of both nausea and vomiting. It is a simple
effective solution and its routine use can be suggested in
gynecological laparoscopic surgery. |
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| Keywords: Clonidine, Nausea &, Vomiting, Laparoscopy |
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Full-Text [PDF 235 kb]
(1003 Downloads)
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Type of Study: Research |
Subject:
Special
Received: 2015/06/1 | Accepted: 2015/06/1 | Published: 2015/06/1
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