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:: Volume 15, Issue 4 (1-2011) ::
__Armaghane Danesh__ 2011, 15(4): 335-344 Back to browse issues page
Effect of Soybean on Male Reproductive Physiology in Male Mice
M Modaresi , M Messripour, H Khorami
Abstract:   (3798 Views)
Introduction & Objective: Soybean (Soja hispida Moench) is a member of Fabaceae family. It is a species of legume native to East Asia. Soy contains significant amount of all the essential amino acids for humans therefore, is a good source of protein .Soy has an important role in the improvement and treatment of some cancers such as colon, prostate, and breast. The aim of this study was to investigate the effect of soybeans on reproductive system in male mice. Materials & Methods: This experimental study was conducted at Isfahan Payam e Noor University in 2009. In this research, 32 male mice were randomly grouped into four experimental groups. The control group was fed with soy-free basic diet. The experimental groups 1, 2, and 3 were fed with a diet containing 20%, 30% and 50% soy diet respectively.At the end of 9 weeks of treatment, blood samples were collected and serum levels of testosterone, LH and FSH were measured. The collected data was analyzed with SPSS software using one way ANOVA with Dunnett's post test and Duncan test. Results : In the experimental group which received 20% soy diet, the level of testosterone had a meaningful decrease in comparison with the control group (P<0.05), but in the experimental group which received a 50% soy diet, the level of testosterone had a meaningful increase (P<0.05) .The LH level in 30% and 50% groups had a meaningful increase but no significant differences were observed in FSH level & weight of testicles (P<0.05).The number of sperms in all of the treatment regimes had a meaningful decrease (P<0.05), but the mean of testis weight was not significantly different between different groups (P>0.05) Conclusion: Results of this research indicated that the 20, 30, and 50 percent soy diet had a negative effect on the male reproductive system in mice.
Keywords: Soybean, Phetoesterogen, Reproductive Physiology, Mice
Full-Text [PDF 748 kb]   (1727 Downloads)    
Type of Study: Research | Subject: Special
Received: 2015/05/4 | Accepted: 2015/05/4 | Published: 2015/05/4
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Modaresi M, Messripour M, Khorami H. Effect of Soybean on Male Reproductive Physiology in Male Mice. Armaghane danesh. 2011; 15 (4) :335-344
URL: http://armaghanj.yums.ac.ir/article-1-450-en.html

Volume 15, Issue 4 (1-2011) Back to browse issues page
ارمغان دانش Armaghane danesh
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