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:: Volume 22, Number 1 (4-2017) ::
__Armaghane Danesh__ 2017, 22(1): 118-128 Back to browse issues page
The Evaluation of Microorganisms and Risk Factors of Neonatal Sepsis in Patients with Suspected Sepsis in Imam Sajjad Hospital, Yasuj
A Keshtkari1, GH Parsa1, HR Ghafarian Shirazi2, P Koleini 3
1- Department of Pediatrics, Yasuj University of Medical Sciences, Yasuj, Iran,
2- Department of Social Medicine, Yasuj University of Medical Sciences, Yasuj, Iran
3- Department of Social Medicine, Yasuj University of Medical Sciences, Yasuj, Iran , p.kpleini@yahoo.com
Abstract:   (522 Views)
ABSTRACT
 
Background & aim: Nowadays, despite the emergence of newer antimicrobial agents, sepsis remains as a major cause of mortality and disease in neonates. Sepsis is an infection proven by blood culture that can be created from various sources in admitted neonates and increased length of stay, impose heavy costs on the health system and be more pathogenic; therefore, is very important in clinical studies. The aim of this study was to investigate the causative organisms involved in sepsis and risk factors for neonatal infection.
 
Methods: This longitudinal analytic study was done in duration of 8 months on 100 neonates with suspected late-onset sepsis in the neonatal and NICU ward of Imam Sajad Hospital of Yasuj, Iran. The neonates’ blood cultures and risk factors involved in sepsis were evaluated. Due to negative blood cultures obtained, patients with a clinical syndrome SIRS criteria were considered as suspected cases of late sepsis. Chi-square test was performed for the association between potential risk factors and severity of nosocomial infections. Collected data were analyzed using SPSS software and Chi-square test.
 
Results:از میان کشت های خون فرستاده شده از بیماران که 61 ‌( ‌ ‌% ) مورد پسر و 39 ‌( ‌ ‌%)مورد دختر بودند، بجز یک مورد کشت خون مثبت اولیه با استافیلوکوک ارئوس ، هیچ کشت خون مثبتی گزارش نشد. از میان بیماران انتخاب شده 57 مورد ‌(57 ‌% کمتر از 37 هفته و 43 مورد ‌( ‌ ‌% ) بیشتراز 37 هفته بودند که دراین بیماران ،نارس ی ارتباط معنی داری ( p‌=‌ ‌‌) از نظر ابتلا به سپسیس داشت. از میان بیماران هنگام بستری 78 مورد ‌( ‌ ‌% سن بستری کمتر از 24 ساعت داشتند که ارتباط معنی داری ‌( ‌= 0.01 ) Of 100  culture samples  only 1 positive blood culture with Staphylococcus aureus was identified. SIRS syndrome was confirmed in 61 patients, of which 47 cases with two criteria and 14 cases were diagnosed with three criteria in this clinical situation. In the statistical analysis, patient examination more than three times in 24 hours (P = 0.026) had significant statistical correlation with SIRS criteria in neonates.
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Conclusion: In hospitals that employ of artificial media to identify the blood culture proven sepsis should be not satisfied as the only way out. The most important risk factor for late-onset sepsis in this study, high contact with patients for clinical examination is presented.
 
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Keywords: Neonate, Sepsis, SIRS syndrome, Risk factors
Full-Text [PDF 188 kb]   (201 Downloads)    
Type of Study: Research | Subject: Clinical
Received: 2016/07/26 | Accepted: 2017/05/5 | Published: 2017/05/5
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Keshtkari A, Parsa G, Ghafarian Shirazi H, Koleini P. The Evaluation of Microorganisms and Risk Factors of Neonatal Sepsis in Patients with Suspected Sepsis in Imam Sajjad Hospital, Yasuj . Armaghane danesh. 2017; 22 (1) :118-128
URL: http://armaghanj.yums.ac.ir/article-1-981-en.html
Volume 22, Number 1 (4-2017) Back to browse issues page
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