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The Effect of Cinnamon (Bark) Extract on Male Reproductive Physiology in Mice
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M Modaresi   1, M Messripour , R Rajaei |
| 1- , mehrdad_modaresi@hotmail.com |
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Abstract: (6377 Views) |
| ABSTRACT:
Introduction and Objective: Cinnamon is a plant with the scientific name Cinnamomum zeylanicum that belongs to the Lauraceae family. This plant has many therapeutic effects one of them is the increasing of sexual desire. This study was conducted to find out the effects of Cinnamon extracts on reproductive physiology of male laboratory mice.
Materials and Methods: Animals were assigned in six groups, each consisted of eight mice. The mice groups were experimental groups (1, 2, 3, 4) and two control and placebo groups. All animals were kept in same condition. Different doses of Cinnamon hydro-ethanolic extract (50,100,200 and 400mg/kg/2day) were injected, intraperitonealy, to animals for 20 days while the control group received normal saline plus ethanol. The most important parameters in this study were included: variation in testicles weight, probabe histological changes in testes, changes in number of sexual cells and density of LH, FSH and testosterone in blood of the subjects.
Results: The results indicated that cinnamon can significantly increase the level of LH and FSH in doses of 200, 400 mg/kg. The density of testosterone increased in dose of 50, 100 mg/kg also the number of sperms and primary spermatocytes raise in 100, 200 and 400 cinnamon extract while no significant changes were observed in weight of testicles and also in histological findings.
Conclusion: The findings of this research indicated the positive effects of cinnamon extract on male reproductive system and hormonal changes in pituitary-gonad axis because sperm count and secretion of FSH hormone had a meaningful significance in dose of 200 and400 mg/kg of the cinnamon extract. |
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| Keywords: KEYWORDS: Cinnamomum zeylanicum, Mice, Male reproductive system, Testosterone |
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Full-Text [PDF 957 kb]
(1768 Downloads)
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Type of Study: Research |
Subject:
Special
Received: 2015/05/26 | Accepted: 2015/05/26 | Published: 2015/05/26
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