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:: Volume 19, Issue 2 (5-2014) ::
__Armaghane Danesh__ 2014, 19(2): 146-160 Back to browse issues page
Depression and Sub-clinical Markers of Multiple Sclerosis
GH Salehpoor 1, SM Kafi, S Rezaei, M Hosseininezhad, I Salehi
1- , maisam.salehpoor@yahoo.com
Abstract:   (3160 Views)
Abstract Background & aim: Multiple sclerosis is a chronic neurological disease that depression has been found in more than 40% of its patients and by several sub-clinical markers associated with disease the opportunity will appearance. Aim of this present study was investigation depression and multiple sclerosis sub-clinical markers. Methods: In this analytical cross-sectional study, 162 patients with multiple sclerosis were selected by consecutive sampling and using the clinical and demographic variables inventory, Depression, Anxiety and Stress Scale, Short Form Health Survey questionnaire, Fatigue Severity Scale along with identical analog-spring balance were examined. The data were analyzed by pearson correlation coefficient, one way analysis of variance, Tukey's test and stepwise multiple regression. Results: Patients with 3 or more times the number of relapses and hospitalizations experienced, received significantly more depression scores than patients with lower frequent relapse and hospitalization. In addition, sub-clinical markers of the disease together could explain 30% of the shared variance of depression. Overall in final step limitations due to physical problems, fatigue and bodily pain could significantly predicts depression scores in patients (P <0.0001). Conclusion: This study highlighted the impact of multiple sclerosis sub-clinical markers in depression of patients. Hence, is requirement that identified key predictors of this research be considered as possible risk factors in development of depression associated with multiple sclerosis and used for the regular management of the disease. Key words: Multiple Sclerosis, Depression, Fatigue, Pain
Keywords: Key words: Multiple Sclerosis, Depression, Fatigue, Pain
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Type of Study: Research | Subject: Special
Received: 2015/05/4 | Accepted: 2015/05/4 | Published: 2015/05/4
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Salehpoor G, Kafi S, Rezaei S, Hosseininezhad M, Salehi I. Depression and Sub-clinical Markers of Multiple Sclerosis. Armaghane danesh. 2014; 19 (2) :146-160
URL: http://armaghanj.yums.ac.ir/article-1-443-en.html

Volume 19, Issue 2 (5-2014) Back to browse issues page
ارمغان دانش Armaghane danesh
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