Abstract
Background & Aim: The effective method of Polycystic Ovary Syndrome treatment is lifestyle modification. The aim of this study was to determine the effect of a twelve-week aerobic exercise on Ovarian Androgens and Body Composition of women with Polycystic Ovary Syndrome.
Methods: In this clinical trial, 20 obese patients (BMI>25 kg/m2) and 20 lean patients (BMI<20 kg/m2) with Polycystic Ovary Syndrome were selected. Lean and obese patients were randomly divided into intervention and control groups. The intervention group participated in a 12 week, 3 sessions per week with intensity 65-80% of maximal heart rate for 25 - 30 minutes of aerobic exercise, while this intervention was not performed in the control group. BMI, WHR, LH, FSH, prolactin and iestosterone hormones were measured before and after the intervention. The data were analyzed using the Paired and independent T tests.
Results: BMI decreased significantly after exercise in obese group (P<0.0001). The reduction of prolactin was not significant after exercise in both lean and obese groups (P>0.05). LH/FSH significantly decreased after exercise in the lean group (P=0.049).The testosterone concentration was significantly decreased after exercise in both lean and obese groups (P<0.05).
Conclusion: A period of exercise with body weight loss and reduction of BMI can contribute to the decline of testosterone concentration, decrease of LH/FSH ratio, improvement of metabolic condition. It prevents the increasing of prolactin and also the side effects of hyperandrogenism.
Keywords: Exercise, PCOS, Prolactin, Testosterone
Gaeini A, Satarifard S, Mohamadi F, Rajaei M. Exercise on Ovarian Androgens and Body Composition of Women with Polycystic Ovary Syndrome. armaghanj 2012; 17 (5) :387-397 URL: http://armaghanj.yums.ac.ir/article-1-407-en.html