|
Investigating the changes in the levels of liver inflammatory markers to two types of aerobic and resistance training combined with the consumption of cinnamon supplements in obese rats
|
I Fathi1   , V Ghanbari Mazidi2 , Z Navidi3 |
1- Department of Exercise Physiology, Vali-e-Asr University of Rafsanjan, Rafsanjan, Iran , imanfathi@gmail.com
2- Department of Exercise Physiology, Vali-e-Asr University of Rafsanjan, Rafsanjan, Iran
3- Department of Anesthesiology, Ali Ibn Abitaleb Educational and Treatment Hospital, Rafsanjan University of Medical Sciences, Rafsanjan, Iran. |
|
|
Abstract: (1883 Views) |
Background & aim: It is now well-established that obesity is a significant health problem as it can lead to various diseases, including fatty liver. The aim of this study was to determine and compare the changes in levels of hepatic inflammatory indicators in response to two types of aerobic and resistance exercise training combined with cinnamon supplementation in obese rats.
Methods: The present fundamental-applied experimental study was conducted in 2023. After a two-month period of obesity induction through a high-fat diet, 42 male Wistar rats were divided into 7 groups: Control, Obese Control, Obese Cinnamon, Obese Aerobic Exercise, Obese Resistance Exercise, Obese Aerobic Exercise-Cinnamon, and Obese Resistance Exercise-Cinnamon. The supplement groups received 200 mg/kg/day of cinnamon extract. The exercise groups performed their training protocols for 4 weeks, 4 days per week. The Control and Obese Control groups received no intervention. To control for the effect of diet, the rats continued to have access to the high-fat diet during the one-month exercise period. Collected data were analyzed using one-way ANOVA and Bonferroni's post-hoc test.
Results: The results indicated a significant decrease in the levels of Alanine Transaminase (p=0.011), Aspartate Aminotransferase (p=0.025), and Alkaline Phosphatase (p=0.018) in the Aerobic Exercise group compared to the Obese Control group. Furthermore, the levels of Alanine Transaminase (p=0.005), Aspartate Aminotransferase (p=0.043), and Alkaline Phosphatase (p=0.041) in the Resistance Exercise group showed a significant decrease compared to the Obese Control group. However, no significant difference was observed between the Aerobic and Resistance Exercise groups.
Conclusion: It appeared that for individuals dealing with obesity and overweight, performing either aerobic or resistance exercises along with cinnamon consumption can help improve hepatic inflammatory indicators.
|
|
| Keywords: liver inflammatory factors, Aerobic training, Resistance training, ALT, AST, ALP |
|
|
Full-Text [PDF 705 kb]
(21 Downloads)
|
Type of Study: Research |
Subject:
Sport Physiology
Received: 2024/12/17 | Accepted: 2025/02/24 | Published: 2025/05/6
|
|
|
|
|
|
|
| Send email to the article author |
|
|
|
| Add your comments about this article |
|
|
|
