[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
Journal Information::
Articles archive::
For Authors::
For Reviewers::
Registration::
Contact us::
Site Facilities::
Indexing & Abstracting::
Publication Ethics::
::
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
Indexing & Abstracting
DOAJ
GOOGLE SCHOLAR
..
:: Volume 18, Issue 5 (9-2013) ::
__Armaghane Danesh__ 2013, 18(5): 389-399 Back to browse issues page
Cytotoxicity of Dorema auchri, Achillea millefolium and Artemisia aucheri by Artemia
M Ghavamizadeh , J Mohammadi , A Mirzaei 1, H Sadeghi , M Akbartabar
1- , Mirzaei3a2003@yahoo.com
Abstract:   (4957 Views)
Abstract Background & aim: Nowadays, toxic compounds derived from plants used against microbes and cancer cells. The aim of this study was to evaluate cytotoxicity of Dorema aucheri, Achillea millefollium and Artemisia aucheri using brine shrimp, Artemia urmiana, lethality test. Methods: In this experimental study, the plants were collected from the Kohgiluyeh and Boyer-Ahmad Province, then identified by a botanist. Clean and air-dried aerial parts of plants were extracted with suitable solvents. Cytotoxicity evaluation was performed using larvae hatched cysts were purchased from Urmia. Live larvae were exposed to different concentrations of extract and the numbers of live and dead larvae were counted after 24 hours. Mean of LC 50 of any extracts from control and exposed live larvae were examined. The data were analyzed using the Finney’s Probit analysis. Results: Hydro ethanol and chloroform extracts of Achillea millefolium, Dorema aucheri and Artemisia aucheri exhibited potent brine shrimp lethality with LC50 67.8±0.53μg.ml-1, 76.50±0.60μg.ml-1, 92.70±6.05μg.ml-1 respectively. The degree of lethality was found to be directly proportional to the concentration of extracts. Conclusion: According to BSLT, LC50 of D. aucheri, A. millefolium and A. aucheri, they were considered as toxic. So these plants could be a source of new compounds with biological activity. Key words: Artemia urmiana, Dorema auchri, Achillea millefolium, Artemisia aucheri, Cytotoxicity
Keywords: Key words: Artemia urmiana, Dorema auchri, Achillea millefolium, Artemisia aucheri, Cytotoxicity
Full-Text [PDF 622 kb]   (1903 Downloads)    
Type of Study: Research | Subject: Special
Received: 2015/04/27 | Accepted: 2015/04/27 | Published: 2015/04/27
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Ghavamizadeh M, Mohammadi J, Mirzaei A, Sadeghi H, Akbartabar M. Cytotoxicity of Dorema auchri, Achillea millefolium and Artemisia aucheri by Artemia . armaghanj 2013; 18 (5) :389-399
URL: http://armaghanj.yums.ac.ir/article-1-330-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 18, Issue 5 (9-2013) Back to browse issues page
ارمغان دانش Armaghane Danesh
Persian site map - English site map - Created in 0.04 seconds with 39 queries by YEKTAWEB 4645