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:: Volume 25, Issue 5 (10-2020) ::
__Armaghane Danesh__ 2020, 25(5): 0-0 Back to browse issues page
The effect of mesenchymal stem cell supernatant product derived from adipose tissue on sperm quality increase after defecation
Fahimeh Seghayati Mrs1, Reza Tabatabaei Mr.2, Sima Nasri Dr. 3
1- Payame Noor univ.
2- Tehran Univ.
3- Payame Noor univ. , s_nasri2000@yahoo.com
Abstract:   (125 Views)
Background & Goal: Infertility and the resulting individual and social problems are one of the main and most important issues and concerns of couples, and about half of all infertility is related to men. In the present study of mesenchymal stem cell supernatant products derived from Adipose tissue has been used as a preservative and sperm damage after defecation has been evaluated. Material & method: This study was performed on 20 infertile men referred to the Qom University Jihad Infertility Center. All of these men have asthenospermia. Simonchr('39')s samples were taken from these individuals and then pre-freeze measurements were performed, such as survival, DNA failure rate, malondialdehyde level, and oxidative stress on sperm. After that, the stem cells were frozen with the supernatant product and the same phallic studies were performed on the deflated sample. Findings:The results of this study showed that the survival rate after defecation increased in some supernatant concentrations (P <0.05) but there was little difference in DNA failure and oxidative stress (P> 0.05). The amount of malondialdehyde also changed (P <0.05). Discussion: Due to the positive effect on sperm and increasing their quality after defecation, using the supernatant of fat-producing mesenchymal stem cells, it can be used as a suitable preservative alone or in combination with other supplements.
 
Keywords: Asthenospermia, Mesenchymal Stem Cells, Malondialdehyde, DNA Failure
     
Type of Study: Research | Subject: Physiology
Received: 2020/06/13 | Accepted: 2020/10/31 | Published: 2020/11/7
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Seghayati F, Tabatabaei R, Nasri S. The effect of mesenchymal stem cell supernatant product derived from adipose tissue on sperm quality increase after defecation. Armaghane danesh. 2020; 25 (5)
URL: http://armaghanj.yums.ac.ir/article-1-2821-en.html


Volume 25, Issue 5 (10-2020) Back to browse issues page
ارمغان دانش Armaghane danesh
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