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:: Volume 24, Issue 6 (12-2019) ::
__Armaghane Danesh__ 2019, 24(6): 0-0 Back to browse issues page
Sympathetic Skin Response in patients with major depressive disorders
Hamid Reza Farpour Dr.1 , Azade Hajihosseini Dr.1 , Ebrahim Moghimi Sarani Dr. 2, Elham Nasrolahi Dr.1 , Hadi Raeisi Shahraki Dr.3
1- Shiraz University of Medical Sciences, Shiraz, Iran
2- Shiraz University of Medical Sciences, Shiraz, Iran , moghimiebrahim@yahoo.com
3- Shahrekord University of Medical Sciences, Shahrekord, Iran
Abstract:   (685 Views)
Introduction: Major depressive disorder (MDD) is one of the most prevalent diseases of psychiatry. There is evidence that suggests the autonomic nervous system plays a role in depression. Sympathetic Skin Response (SSR) is used to evaluate the autonomic system. Nerve Conduction Study (NCS) evaluates peripheral thick myelinated fibers. In SSR we evaluate thin unmyelinated fibers. The purpose of this study is evaluation of Sympathetic Skin Response in patients with MDD and control group.
Materials and Methods: The case group include 20 patients (16 women and 4 men), suffering from MDD and control group include 19 subjects (12 women and 7 men) with mean age of 7.8431.65 and 6.99 32.10. Bilateral palmar and plantar latency and amplitude of SSR were recorded in response to Median and Tibial nerve electrical stimulation.
Results: The data received from this study showed an increase in SSR amplitude in the case group compared to the controlled group in the upper extremities. In the lower extremities difference in SSR amplitude was not observed. There was no difference in SSR latencies between the case and control group.
Conclusion: The results of this study may suggests that an increase in SSR amplitude in upper extremities can be useful in diagnosis and follow up of patients suffering from MDD and it indicates autonomic nervous system dysfunction in these people.
Keywords: Major Depression Disorder, Amplitude, Latency, Autonomic nervous system, Sympathetic Skin Response, electrodiagnosis .
Type of Study: Research | Subject: Special
Received: 2019/05/6 | Accepted: 2019/12/9 | Published: 2020/01/12
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Farpour H R, Hajihosseini A, Moghimi Sarani E, Nasrolahi E, Raeisi Shahraki H. Sympathetic Skin Response in patients with major depressive disorders. Armaghane danesh. 2019; 24 (6)
URL: http://armaghanj.yums.ac.ir/article-1-2516-en.html

Volume 24, Issue 6 (12-2019) Back to browse issues page
ارمغان دانش Armaghane danesh
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