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:: Volume 24, Issue 1 (4-2019) ::
__Armaghane Danesh__ 2019, 24(1): 0-0 Back to browse issues page
The Effect of Pre-preparation aerobic exercises on cerebellar Purkinje cells in Parkinson’s rats with prenatal stress
Abstract:   (84 Views)
Abstract
Target:  Parkinson's disease is a disorder in the nervous system due to the degeneration of dopaminergic neurons. Dopaminergic system is susceptible to neurological disorders caused by exposure to stressors early. Positive experiences are one of the most powerful treatments to increase neuroplasticity and motor function at any time of life. The purpose of this study was to investigate the effect of pre-treatment endurance training on the balance of Parkinson's rats with perinatal stress.
Materials and methods: : A Laboratory research method was used. 48 Wistar male rats 30 days old, half of them under prenatal stress And followed up on endurance exercise. Were divided into 8 groups of 6, with stress (control, sham, parkinson, parkinson + endurance exercise) and without stress (control, sham, parkinson, parkinson + endurance exercise). Animals underwent Stereotaxic surgery after 8 weeks, after three weeks, the apomorphine test used to detect Parkinson's disease and balance beam test to assess the balance.  Data were analyzed using two way ANOVA and Tukey's .
Findings:The findings showed that endurance exercise resulted in better balance in both groups with and without prenatal stress (P <0.05).  also Prenatal stress reduced balance, but this was not significant(P=0/059) and prenatal stress reduced the beneficial effects of exercise on the balance test (P <0.05).  Prenatal stress also reduced balance, but this was not significant
Discussion and conclusion: According to the findings of this study, prenatal stress can reduce the balance of Parkinson's rats.Endurance exercises reduce the negative effects of perinatal stress, which will result in a reduction in the negative effects of Parkinson's on balance.

 
 
Keywords: Keywords: Pre-preparation, Parkinson's disease, stress, Balance, endurance exercises
     
Type of Study: Research | Subject: Sport Physiology
Received: 2019/03/6 | Accepted: 2019/03/6 | Published: 2019/03/6
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The Effect of Pre-preparation aerobic exercises on cerebellar Purkinje cells in Parkinson’s rats with prenatal stress . Armaghane danesh. 2019; 24 (1)
URL: http://armaghanj.yums.ac.ir/article-1-2457-en.html


Volume 24, Issue 1 (4-2019) Back to browse issues page
ارمغان دانش Armaghane danesh
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