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:: Volume 19, Issue 1 (4-2014) ::
__Armaghane Danesh__ 2014, 19(1): 47-55 Back to browse issues page
Aloe Vera Extract Effect on Sperm Quality and Testicular Tissue of Rats Induced by Cadmium Chloride
F Farhangdoost , M Jafari Barmak, V Hemayatkhah Jahromi, A Azizi, R Mahmoodi, E Keshavarzi, M Naraki
Abstract:   (4960 Views)
Background & aim: A lot of physical and chemical factors cause infertility disorders. Cadmium is a chemical agent which damages the cell structure of the reproductive system. For reducing the effects of various factors, new traditional methods have been used. The aim of this study was to investigate the effects of Aloe vera extract on testicular tissue of rats induced by cadmium chloride. Methods: In this experimental study, 40 male Wistar rats (180-200 gr) were randomly divided into four groups. Groups 1 and 2 received Cadmium chloride (1/5 mg / kg/ IP). Mice induced by cadmium chloride were treated with Aloe vera. Control and normal rats were treated with 400 mg/kg of Aloe vera extracts. After 25 days, these rats were weighed and then anesthetized using ether. Blood samples were collected from each individual to assess the level of testosterone and then the animals were debriefed. The testes were removed and transferred to 10% formalin solution. After tissue processing, 5 micron sections were prepared and stained with heamatoxillin-eosin and investigated by light microscope. Data were analyzed by one-way ANOVA test. Results: Mean seminiferous tubular diameter, number of spermatogonia, Leydig and Sertoli cell of cadmium control group compared to the healthy control group showed a significant decrease (p<0.05). The mean sperm count and sperm motility in extract cadmium group and healthy control group was close to normal and displayed a significant difference (p< 0.05). Conclusion: Hydroalcoholic extract of Aloe vera increases the number of spermatogonia, Leydig and Sertoli testicular tissue of mice contaminated with cadmium chloride
Keywords: Aloe Vera, Cadmium Chloride, testicular, sperm quality, Sertoli cell, Leydig cell
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Type of Study: Research | Subject: Special
Received: 2015/04/15 | Accepted: 2015/04/15 | Published: 2015/04/15
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Farhangdoost F, Jafari Barmak M, Hemayatkhah Jahromi V, Azizi A, Mahmoodi R, Keshavarzi E et al . Aloe Vera Extract Effect on Sperm Quality and Testicular Tissue of Rats Induced by Cadmium Chloride. Armaghane danesh. 2014; 19 (1) :47-55
URL: http://armaghanj.yums.ac.ir/article-1-224-en.html


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Volume 19, Issue 1 (4-2014) Back to browse issues page
ارمغان دانش Armaghane danesh
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