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The Petroselinum crispum L. hydroalcoholic extract effects on pituitary- gonad axis in adult Rats
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F Bastampoor   , H Sadeghi , SE Hosseini |
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Abstract: (4625 Views) |
| Background & aim: Infertility is one of the major issues in medical science which various chemical and herbal medicines have been used for its treatment from ancient times. Due to the side effects of chemical drugs and with regard to the cause of infertility in men is a hormonal disorder, thus, the study aimed to investigate the effect of ethanol extracts of parsley leaves performed on serum levels of pituitary - gonadal hormones.
Methods: The present experimental study was conducted on fifty adult male rats. The animals were divided into 5 groups of 10 specimens, including controls, and three sets of empirical receiving doses 1000, 1500 and 2000 mg/kg ethanol extract of parsley leaves respectively. Prescriptions were done as gavage for 28 days. At the end of the test, the hearts of the animal and the serum hormones levels of testosterone, FSH and LH were measured. The Data were analyzed with t-test and Duncan and significant differences of data was considered at p = 0.05.
Results: The findings revealed that the leaf extract of parsley caused a significant increase in FSH and LH and testosterone significantly increased at minimum and medium doses and decreased significantly in maximum dose.
Conclusion: Parsley leaf , having antioxidant compounds, led to the increasing of FSH and LH hormones at three doses and increasing testosterone at minimum and medium doses and decreasing at maximum dose. |
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| Keywords: Petroselinum crispum Extract, LH, FSH, Testosterone |
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Full-Text [PDF 311 kb]
(1326 Downloads)
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Type of Study: Research |
Subject:
Special
Received: 2015/04/12 | Accepted: 2015/04/12 | Published: 2015/04/12
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