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:: Volume 22, Number 4 (7-2017) ::
__Armaghane Danesh__ 2017, 22(4): 0-0 Back to browse issues page
Predictive factors of positive blood culture in sepsis
Dr Mansooreh Momen-Heravi1, Dr Reza Razzaghi 2, Dr Hasan Afzali3, Amin Tahmoores4
1- associate Prof kashan university of medical sciences
2- assistant prof kashan university of medical sciences , rezarazzaghi33@yahoocom
3- Professor kashan university of medical sciences
4- gp
Abstract:   (107 Views)
Background Blood culture is one of methods to determine the microbial etiology of  sepsis. but  isolatin  of  organism  is difficult  because of low level of organism  in blood or use of antibiotic  .This study was conducted to evaluate predictive factors of positive blood culture in sepsis patients.
Materials & Methods This historical  cohort  study were done on 320 patients with sepsis during October 2014 to October 2015 who were admitted to the Kashan’s Shahid Beheshti Hospital. By investigation patients' medical records, demographic, clinical and laboratory data such as age, sex, history of hospitalization, temperature, blood pressure, tachycardia, tachypnea, C reactive protein (CRP )serum levels, white blood cell count, erythrocyte sedimentation rate(ESR) and outcomes were extracted. Chi square, Mann-Witney U and t-test were used in data analysis.
Results The mean age of patients in the group with positive cultures (case groups) was 67.93±12.12 years and in patients with negative culture (control group) was 64.67±13.87 years (p=0.03). The frequency of the underlying disease, recent hospitalization, hypotension and tachypnea in the case group was significantly more than control group. Logistic regression analysis showed that CRP serum levels, erythrocyte sedimentation rate and white blood cell counts in patients with sepsis are associated with blood culture results. Data was analyzed using the SPSS version 16 software.
Conclusion
In this study difference between two group according to age,sex, nationality, mean temperature, tachycardia,loss of consciousness,and mortality was not significant but there was significant association between underlying disease,history of hospitaliztion,hypotension,tachpnea, CRP,ESR,WBC. And finally  concluded that  CRP,ESR,WBC was associated with posistve blood culture but  this association was not between  positive blood culture   and mortality
.
Key words: Sepsis, blood cultures, Predictive factors
 

Keywords: Sepsis, blood cultures, Predictive factors
     
Type of Study: Research | Subject: Infectious Disease
Received: 2016/08/28 | Accepted: 2017/09/18 | Published: 2017/09/28
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Momen-Heravi M, Razzaghi R, Afzali H, Tahmoores A. Predictive factors of positive blood culture in sepsis . Armaghane danesh. 2017; 22 (4)
URL: http://armaghanj.yums.ac.ir/article-1-1486-en.html
Volume 22, Number 4 (7-2017) Back to browse issues page
ارمغان دانش Armaghane danesh
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