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Introduction & Objective: Plants from the genus Pistacia family such as Pistacia atlantica, Pistacia vera and Pistacia khynjuk are considered as herbal medicines. Antibacterial and anti-inflammatory effects of these plants have been confirmed. The aim of the current study was to find the effect of Pistacia khynjuk on humoral immune system of Wistar rats. Materials & Methods: This is an experimental study which was conducted at Yasuj University of Medical Sciences in 2009. Forty male Wistar rats were randomly allocated into four groups of ten animals and orally received 10 mg/kg of the extract of nucleus, cutin and fruit of Pistacia khynjuk respectively, every day for two weeks. The control group received only placebo. Immuno-reactivity was induced using BCG vaccine (IP) with Freund‘s complete adjuvant (CFA). The titer of IgG and IgM were measured after the treatment using ELISA method. Moreover, the cervical lymph nodes and spleen of animals were excised and the volume and density of the primary and secondary follicle was evaluated by steriology. The collected data were analyzed by the SPSS using one-way ANOVA. Results: The differences in the mean level of IgG and IgM between the treated and the control animals were not significant (p>.05). Also, the mean volume of the spleen and cervical lymph nodes of the first three groups in comparison with the control animals were not significant (p>.05). Conclusion: Findings of this study showed that the Pistacia khynjuk did not have any direct effect on the activity of humoral immune system and the increasing of antibody level among Wistar rats.

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Introduction & Objective: Dogs are among the closest animals to human residents and can by useful for human. A few of zoontic diseases are prevalent in Iran. Dogs are the reservoirs of many of these zoonosis and a major role in transmission of infection. The aim of this study was to determine the zoonotic parasitic fauna of stray dogs in Yasuj Materials & Methods: In this descriptive study which was conducted at Yasuj suburbs in 2008, 25 dogs’ corpses were necropsied and their tissues were studied for parasitic infections. Collected parasites were placed in special containers and stained for genus and species diagnosis based on their morphological features. The collected data were analyzed with the SPSS software, using descriptive analysis. Results: Of the 25 studied corpses, 23 dogs were infected with at least one parasite. Helminthic infections of dogs were consisted of: Taenia hydatigena, Mesocestoides sp., Echinococcus granulosus, Dipylidium caninum, Macracanthorhynchus hirudinaceus and Spirocerca lupi. Conclusion: Four of six detected helminthes in in dogs in this study are zoonotic parasites which are important in human diseases. Among them larval stage of Echinococcus granulosus which causes hydatid cyst disease in human is very important. Control programs should be implemented in this region to prevent these zoonotic diseases.

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Introduction & Objective: Some of natural and synthetic products have antioxidant properties which protect the liver against the destructive factors. This study aimed to investigate the effect of Zizphus Vulgaris extracts on mice liver. Materials & Methods: This experimental study was conducted at Yasouj University of Medical Sciences in 2010 on 30 healthy adult male Wistar rats. Animals were randomly divided into five equal groups: the control group (receiving, olive oil), control group (receiving olive oil and carbon tetrachloride and three intervention groups (receiving different dose of carbon tetrachloride and olive oil) groups. The intervention group was given daily doses of 200, 400 and 600 mg per Kg of Zizphus Vulgaris extract by gavage respectively. After 45 days, the amount of liver enzymes, total protein, albumin and bilirubin in animal’s sera were measured. Data were analyzed by the SPSS software, using ANOVA and t-test. Results: The concentration of total protein, albumin, AST, ALT, ALP in test groups I, II and III receiving Z.Vulgaris extract (200, 400 and 600 mg/kg weight) compared with control group were statistically not significant. Consumption of Z.Vulgaris reduced the bilirubin concentration in test groups I and II but this decrease was significant only in the test group I Increasing of Z.Vulgaris dose in the test group III (600 mg Z.Vulgaris per kg body weight) showed increase in the level of serum bilirubin. Increase in the ratio of liver weight to body weight of rats in groups I and III in comparison with control groups was noticed although this difference was not statistically significant. Findings of this study revealed that dosage of 600 mg/kg extract of Z.Vulgaris caused significant improvements in CCl4 induced liver necrosis (P <0.01) and reduced portal cells inflammation (P <0.01). Dose of 400 mg/kg of Z.Vulgaris induced some destruction and necrosis of liver cells in animals but significant reduction of portal cells inflammation was seen. Conclusion: Considering the obtained results, it seems that Ziziphus vulgaris fruit extract has shielding effects against toxins on liver cells.

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Background & aim: Multiple sclerosis is a chronic disease of the nervous system which usually begins in young adults and pathologically characterized by demyelination and glial scarring. According to psychological problems after suffering, the aim of this study was to investigate the influence of religious coping on quality of life in patients with MS. Methods: In the present descriptive study, forty-three patients with multiple sclerosis referred to the CNS Center of Ali bin Abi Talib Hospital of Zahedan, Iran, in 2013 were selected. Using religious coping and quality of life, variables were assessed. The data were analyzed by using the correlation and step-wise regression methods. Results: A positive correlation were seen between religious coping with the passive role due to emotional problems (of QOL) and between religious activities and democratic assessments a significant (p<0.05). The regression results also showed that religious activities in the first step alone 0.07 changed the psychological quality of life and in the second step religious activity along with passive religious coping predicted 0.2 of changes of psychological quality of life. Conclusion: Increasing religious and spiritual activities may contribute to improving the quality of life in patients with multiple sclerosis.

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Background & aim: Drug misuse is defined as inappropriate administration or usage of drug which can be preventable. The aim of study was to identify the consistency rate of drug record information between cardex and patients medical cards in teaching hospitals of Yasuj, Iran Methods: The present descriptive sectional study was conducted in teaching hospitals of Yasuj in 2012. Case Sampling was convenience sampling. A number of 400 patient’s charts were selected and drug orders were compared with cardex and drug patient’s cards. Statistical analysis was performed by SPSS software and descriptive tests. Results: Of 400 charts, only 1670 charts had drug orders and there were a total 337 of drug errors in cardex and drug cards. The highest rate of inconsistency of drug details was related to entering drug routes into cradex and drug cards that were reported 41% and 43.2 % respectively. In addition about 5% and 23.4% of administrated drugs were not recorded in cardex and drug cards. It is also indicated that 1% and 2.5 % of deleted drug orders in the chart were not deleted in cardex and drug cards. Conclusions: There are relatively large numbers of inconsistency cases of drug details between cardex, drug cards and patient’s charts. It is necessary to clarify the issue, and also performed new methods of drug registration in the hospitals.

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Background & aim: Mentally retarded children need more care on quality of life, therefore the family plays an important role, but the results indicate low levels of quality of life for these children and their families. The present study aimed to measure the quality of life in mothers of educable mentally retarded daughter motivated provide a model to measure quality of life and understanding of issues affecting the design. An attempt to investigate and describe the factors affecting the quality of family life with a disability and the relationship between these indicators and how to measure them families with children with mental retardation.

 

Methods: The research method was descriptive-analytic. The sample consisted of 75 mothers with a mentally retarded daughter who were participated in this study through census sampling. By studying literature, the related texts criteria of quality of life were extracted. All study information of participants was obtained by standard questionnaires. Using correlation analysis techniques, univariate regression, logistic regression analysis were analyzed through structural equations.

 

Results: The results indicated that the performance of family (family interactions, parenting, mental health and physical) capabilities mother (resilience and aggression), personal beliefs and quality of life of families with disabled children influenced it. Personal beliefs are an important determinant of quality of life.

 

Conclusion: The results of structural equation modeling and corresponding indexes indicated that the proposed model based on experimental data fitting was good and desirable product was in compliance with the conceptual model.

 

 

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Background & aim: Nowadays, Diabetes is prevalent in different societies, and hyperlipidemia is one of the important outcomes and effective in the development of complications from this disease. Therefore, finding a medication to reduce hyperlipidemia without an adverse effects on blood sugar levels has always been investigated. Some studies have been reported the beneficial effects of the aerial parts of Anethum graveolens on lipid levels in the clinical and animal models. As there is no study on the effect of dill seed extract on blood lipid levels in diabetic rats; the aim of this study was to evaluate the effect of the dill seed extract on lipid profile in diabetic rats.

Methods: In this experimental study, 24 rats with a weight range of 200 to 250 g were randomly divided into three groups of eight, including normal group, diabetic group (received normal saline) and diabetic group (received seed extract to 100 mg /kg). To induce diabetes, the rats were received streptozocin (50 mg /kg,) intraperitoneally. The dill seed extract was given for four weeks and then the blood samples were collected to measure LDL, HDL and triglyceride. The differences between the control and treatment groups were tested by one-way analyses of variance (ANOVA) followed by the Tukey post-hoc test.

Results: Induction of diabetes significantly increased the serum concentration of LDL and triglycerides compared with the control group (p=0.001), but no effect was seen on HDL levels. Dill Oral administration of seed extract-dose (100 mg/kg) animal serum concentration of LDL significantly reduced in comparison with diabetic group (p=0.001). The triglyceride serum levels was significantly reduced compared to diabetic group after 4 weeks administration of dill seed extract (p<0.001), but no effect was observed on HDL in comparison to diabetic group (p=0.54).

Conclusion: The results showed that the dill seed extract was able to reduce the serum levels of LDL and triglyceride in the diabetic rats. So it seems that this extract can reduce cardiovascular complications of diabetes through reducing the blood lipid profile.

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Abstract
 
Introduction: Cardiovascular diseases are the most and common cause of death and debilitation worldwide. Psychological factors compose more than 50 percent of the factors affecting heart diseases. Therefore, this research has been performed aiming to investigate the relationship between religiosity, humor styles and Type- D Personality with general health in the patients with heart disease.
 
Methods: This study is descriptive of correlation type. The statistical population of this research includes all patients with heart disease is the city of Yazd in the years 2016. The study sample consisted of 210 patients with heart failure who were selected by means of verge criteria and were selected by purposeful sampling and based on the Kerjesy and Morgan tables. Research variables Measurement tools are included Serajzadeh questionnaire with 24 items of religiosity (DS-14), Martin’s 32-items questionnaire of humor (HSQ-R), Denollet’s type D personality questionnaire, and Goldberg28 items General Health Questionnaire (GHQ-28). Data was analyzed Using SPSS and AMOS Statistical softwares and path analysis within the framework of structural modeling.
 
Results: The results of data analysis showed that there is a positive and significant relationship between the affective religiosity (b=0.08; P<0.05), other component of religiosity Other components of religiosity including religious beliefs, consequential religions and religious rituals do not show a significant relationship with general health (P>0.05). Affiliative humor had positive and significant relationship with general health (b=0.18; P<0.05), While other humor styles, including self-enhancing wit, aggressive humor and selfish wit, do not show a meaningful relationship with general health (P>0.05). Finally, two component of type D personality including social inhibition (b=-0.20; P<0.01), and negative affect (b=-0.28; P<0.01), have a negative and significant relationship with general health.
 
Conclusion: Base on the result of this research affective religiosity, affiliative humor styles, and Type- D personality are important and affecting risk factors in the general health of patients with heart disease. So, by recognizing such factors, the individuals predisposed to this disease can be identified for preventative measures and helping in treatment.