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Abstract Background & aim: Tonsillectomy as one of the most prevalent surgical operations in otolaryngology is followed by great pain and absences from school and work in most patients. The aim of the present study was a comparison of radiofrequency bipolar cautery in tonsillectomy use. Methods: This clinical trial study was conducted on 33 patients older than 10 years-old candidate for tonsillectomy. Radiofrequency and Bipolar techniques were performed on the right and left tonsils of each studied patient, respectively. Data on pain, bleeding, operation duration and hardness was collected and analyzed by SPSS software, version 15. P-value less than 0.05 was considered statistically significant. Results: Bleeding volume did not statistically differ between two techniques while for other studied factors, statistically significant differences were observed in favor of radiofrequency method (P<0.05). The mean pain intensity in the Radiofrequency procedures on different days after surgery was significantly lower than that of bipolar cautery (P<0.05). Conclusion: Due to our results, the mean score of post-tonsillectomy pain was significantly less following radiofrequency technique in compare with bipolar technique. Key words: Tonsillectomy, Radiofrequency, Pain, Bleeding