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:: Volume 26, Issue 4 (9-2021) ::
__Armaghane Danesh__ 2021, 26(4): 0-0 Back to browse issues page
Comparison of Effect L-Arginine and intravenous fluid Therapy in Oligohydramnios
Shahla Nasrolahi , Maryam Farzanmehr , Mohammad Faryadras 1
1- , feryadresmohammad@gmail.com
Abstract:   (72 Views)
Objective: Oligohydramnios (amniotic fluid depletion) is a common problem in pregnancy that is associated with several complications. The aim of this clinical trial study was to compare the effect of L-arginine and fluid therapy alone on oligohydramnios.
Material and Methods: In this clinical trial study, 50 pregnant women with 28 to 36 gestational age weeks and singleton pregnancy with AFI less than 8 cm were randomly divided into two equal intervention groups, L-arginine at a dose of 3 g twice daily with fluid therapy (3 liters of lactate ringer in 24 hours) and the control group were given fluid therapy alone between 1 and 4 weeks based on gestational age and AFI. Changes in amniotic fluid volume before and after the intervention and pregnancy outcomes were assessed in both groups.
Results: After the intervention, the mean AFI increased to 5.44 ± 0.86 in the control group and 85.28 ± 1.51 in the interventional group (P = 0.001).  The mean AFI in both groups showed a significant increase compared to the previous intervention. The mean gestational age in the interventional group at the end of the study compared to the fluid therapy group showed a significant increase (35.24 ± 0.71 vs. 36.72 ± 0.59 cm). The mean Apgar score in the first minute and 5 in the interventional group was significantly higher. Other outcomes were comparable in the two groups.
Conclusion: the use of L-arginine in combination with injectable fluid therapy with increased amniotic fluid volume can be associated with better outcomes
Keywords: Oligohydramnios, fluid therapy, L-arginine
     
Type of Study: Research | Subject: Gynaecology
Received: 2021/07/12 | Accepted: 2021/08/23 | Published: 2021/09/6
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Nasrolahi S, farzanmehr M, Faryadras M. Comparison of Effect L-Arginine and intravenous fluid Therapy in Oligohydramnios. Armaghane danesh. 2021; 26 (4)
URL: http://armaghanj.yums.ac.ir/article-1-3116-en.html


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Volume 26, Issue 4 (9-2021) Back to browse issues page
ارمغان دانش Armaghane danesh
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