Investigating The Relationship Between Personality Traits and Iron Overload in Transfusion-Dependent Thalassemia Patients

Rezapour , M; Bagherzadeh ledari , R; Ghorkhanechi , R; Ahmad abadi , S; Naderisorki , M

doi:10.61186/armaghanj.29.3.386

[Home ] [Archive]

[ فارسی ]

Main Menu

Home

Journal Information

Articles archive

For Authors

For Reviewers

Registration

Contact us

Site Facilities

Indexing & Abstracting

Publication Ethics

Search in website

Receive site information

Indexing & Abstracting

DOAJ
GOOGLE SCHOLAR

Volume 29, Issue 3 (4-2024)

__Armaghane Danesh__ 2024, 29(3): 386-402

Back to browse issues page

Investigating The Relationship Between Personality Traits and Iron Overload in Transfusion-Dependent Thalassemia Patients

M Rezapour¹

, R Bagherzadeh ledari²

, R Ghorkhanechi³

, S Ahmad abadi⁴

, M Naderisorki⁵

1- Psychiatry and Behavioral Sciences Research center, Addiction Institute, Mazandaran University of Medical Sciences, Sari, Iran, , mr.mns.mr@gmail.com
2- Department of Psychiatry, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran,
3- Clinical Psychologist, Razi Psychiatric Hospital, Tehran, Iran
4- Student Research Committee, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
5- Thalassemia Research Center(TRC), Hemoglobinopathy Institute, Mazandaran University of Medical Sciences, Sari, Iran

Abstract: (1627 Views)

Background & aim: Thalassemia is the most common hereditary blood disease, and patients with thalassemia major need continuous blood transfusions to survive. Continuous blood transfusion in these patients is associated with iron. Therefore, the purpose of the present study was to investigate the relationship between personality traits and iron overload in these patients.

Methods: The present descriptive-cross-sectional study was conducted on 150 thalassemia patients who were dependent on blood transfusion in the thalassemia department of Bu Ali Sina Hospital in Sari in 2021. The clinical and laboratory information of the patients were collected using the medical record. At that point, the patients answered the 5-factor neo personality questionnaire, which is a 60-question questionnaire. To analyze the collected data, descriptive statistics such as mean and standard deviation were used in case of normal distribution of the main outcome, and median and IQR indices were used otherwise.

Results: The results indicated that the personality characteristic of conscientiousness was more in people with regular visits than in people with irregular visits (P=0.021). In the study of the relationship between liver iron overload and the regularity of visits, it was perceived that iron overload had a significant relationship with the regularity of visits (P=0.018), so that moderate and severe iron overload was more in people who had irregular visits. But cardiac iron overload had no significant relationship with regular visits (P=0.910). The use of chelators had a significant relationship with the characteristic of neurosis (P=0.021), so that the score of neurosis in patients who took chelators was higher than those who did not use chelators.

Conclusion: The findings of the present study indicated that there was no significant relationship between any of the personality traits with iron overload in patients with transfusion-dependent thalassemia, except for conscientiousness, which was more in people with regular visits than in people with irregular visits.

Keywords: Thalassemia, Iron Overload, Personality Trait

Full-Text [PDF 612 kb] (265 Downloads)

Type of Study: Research | Subject: Neonatology & Newborn Nursery- NICU-Surgery
Received: 2023/11/10 | Accepted: 2024/04/22 | Published: 2024/05/20

References

1. Oliveros O, Trachtenberg F, Haines D, Gerstenberger E, Martin M, Carson S, et al. Pain over time and its effects on life in thalassemia. Am J Hematol 2013; 88(11): 939-43.## [DOI:10.1002/ajh.23565] [PMID] []

2. De Sanctis V, Soliman AT, Yassin MA, Di Maio S, Daar S, Elsedfy H, et al. Hypogonadism in male thalassemia major patients: pathophysiology, diagnosis and treatment. Acta bio-medica: Atenei Parmensis 2018; 89(2-s): 6-15. ##

3. Toumba M, Sergis A, Kanaris C, Skordis N. Endocrine complications in patients with thalassaemia major. Pediatric Endocrinology Reviews: PER 2007; 5(2): 642-8. ##

4. De Sanctis V, Soliman AT, El-Hakim I, Christou S, Mariannis D, Karimi M, et al. Marital status and paternity in patients with transfusion- dependent thalassemia (TDT) and non transfusion-dependent thalassemia (ntdt): an icet - a survey in different countries. Acta bio-medica: Atenei Parmensis 2019; 90(3): 225-37. ##

5. Hadaegh F, Zare S, Tohidi M. Growth and puberty disorders in major thalassaemic patients in Hormozgan. Iranian Journal of Endocrinology and Metabolism 2003; 5(3): 187-93. ##

6. Mehrvar A, Azar Keyvan A, Saberi Nezhad J, Mehrvar N, Faranoush M. Vosough parvaneh. prevalence of sexual mutation rate abnormalities in patients with 8 thalassemia in Iran. Annals Of Military And Health Sciences Research[Internet] 2007; 5(2 (Serial Number18)): 1233-38. ##

7. Nouri N, Breiri T. Growth and puberty disorders in thalassemia major over 10 years old in Hazrat Ali Asghar (AS) Zahedan Hospital 2002. Journal of Medical Science Studies 2002; 3: 191-8. ##

8. Motta I, Bou-Fakhredin R, Taher AT, Cappellini MD. Beta thalassemia: new therapeutic options beyond transfusion and iron chelation. Drugs 2020; 80(11): 1053-63. ## [DOI:10.1007/s40265-020-01341-9] [PMID] []

9. Kattamis A, Forni GL, Aydinok Y, Viprakasit V. Changing patterns in the epidemiology of β‐thalassemia. European Journal of Haematology. 2020 Dec;105(6):692-703. ## [DOI:10.1111/ejh.13512] [PMID] []

10. Gabrielsen JS, Lamb DJ, Lipshultz LI. Iron and a Man's Reproductive Health: the Good, the Bad, and the Ugly. Current Urology Reports 2018; 19(8): 60. ## [DOI:10.1007/s11934-018-0808-x] [PMID] []

11. Siemons LJ, Mahler CH. Hypogonadotropic hypogonadism in hemochromatosis: recovery of reproductive function after iron depletion. The Journal of Clinical Endocrinology and Metabolism 1987; 65(3): 585-7. ## [DOI:10.1210/jcem-65-3-585] [PMID]

12. Mousavinejad SM, Sanagouye Moharer G, Zarban A. The effectiveness of mindfulness-based cognitive therapy on cognitive flexibility and perceived stress of type ii diabetic patients. Middle Eastern Journal of Disability Studies 2018; 8: 10. ##

13. Chen J, Wang H, Zhou J, Feng S. Advances in the understanding of poor graft function following allogeneic hematopoietic stem-cell transplantation. Therapeutic Advances in Hematology 2020; 11: 2040620720948743. ## [DOI:10.1177/2040620720948743] [PMID] []

14. Wechsler SM, Benson N, de Lara Machado W, Bachert CMD, Gums EF. Adult temperament styles: a network analysis of their relationships with the big five personality model. European Journal of Education & Psychology 2018; 11(1): 61-75. ## [DOI:10.30552/ejep.v11i1.186]

15. Payandeh F, Borjali M, Golkar K. The comparison of personality characteristics in women with diabetes type ii and normal women. MEJDS 2020; 10: 55. ##

16. Contractor AA, Armour C, Shea MT, Mota N, Pietrzak RH. Latent profiles of DSM-5 PTSD symptoms and the "Big Five" personality traits. J Anxiety Disord 2016; 37: 10-20. ## [DOI:10.1016/j.janxdis.2015.10.005] [PMID]

17. oe D, Severinsen IG, Saasen SEH, Gracian TI, Olaniyan OS, Pallesen S. Perceived source of anabolic androgenic steroids and the construal of users' personality. Journal of Substance Use 2017; 22(6): 587-91. ## [DOI:10.1080/14659891.2016.1271038]

18. Hatamloo M, Babapour-Kheirodin J. Comparing the behavioral activation/inhibition systems and personality traits among the diabetic and non-diabetic women. KAUMS Journal (FEYZ) 2014; 18(3): 239-46. ##

19. Farmakis D, Porter J, Taher A, Domenica Cappellini M, Angastiniotis M, Eleftheriou A. Thalassaemia international federation guidelines for the management of transfusion-dependent thalassemia. HemaSphere 2022; 6(8): e732. ## [DOI:10.1097/HS9.0000000000000732] [PMID] []

20. Rosen RC, Riley A, Wagner G, Osterloh IH, Kirkpatrick J, Mishra A. The international index of erectile function (IIEF): a multidimensional scale for assessment of erectile dysfunction. Urology 1997; 49(6): 822-30. ## [DOI:10.1016/S0090-4295(97)00238-0] [PMID]

21. Mariam I. The effect of family support, transfusion compliance and self-efficacy on the quality of life of children with thalassemia. KnE Life Sciences 2022; 7: 102-12. ## [DOI:10.18502/kls.v7i2.10293]

22. Quast LF, Gutiérrez-Colina AM, Cushman GK, Rea KE, Eaton CK, Lee JL, et al. Adherence barriers for adolescent and young adult transplant recipients: relations to personality. Journal of Pediatric Psychology 2020; 45(5): 540-9. ## [DOI:10.1093/jpepsy/jsaa017] [PMID]

23. Novak JR, Anderson JR, Johnson MD, Hardy NR, Walker A, Wilcox A, et al. Does personality matter in diabetes adherence? Exploring the pathways between neuroticism and patient adherence in couples with type 2 diabetes. Applied Psychology: Health and Well‐Being 2017; 9(2): 207-27. ## [DOI:10.1111/aphw.12087] [PMID] []

24. Srisukh S, Ongphiphadhanakul B, Bunnag P. Hypogonadism in thalassemia major patients. Journal of Clinical & Translational Endocrinology 2016; 5: 42-5. ## [DOI:10.1016/j.jcte.2016.08.001] [PMID] []

25. Wheeler K, Wagaman A, McCord D. Personality traits as predictors of adherence in adolescents with type I diabetes. Journal of Child and Adolescent Psychiatric Nursing 2012; 25(2): 66-74. ## [DOI:10.1111/j.1744-6171.2012.00329.x] [PMID]

26. Israel S, Moffitt TE. Assessing conscientious personality in primary care: An opportunity for prevention and health promotion. Developmental Psychology 2014; 50: 1475-77. ## [DOI:10.1037/a0036113] [PMID] []

27. Sánchez-Urbano C, Pino MJ, Herruzo C. Personality prototypes in people with Type 1 diabetes and their relationship with adherence. International Journal of Environmental Research and Public Health 2021; 18(9): 4818. ## [DOI:10.3390/ijerph18094818] [PMID] []

28. Patel A, Jacobsen L, Jhaveri R, Bradford KK. Effectiveness of pediatric pill swallowing interventions: A systematic review. Pediatrics 2015; 135: 883-9. ## [DOI:10.1542/peds.2014-2114] [PMID]

29. Denissen JJ, Penke L. Motivational individual reaction norms underlying the Five-Factor model of personality: First steps towards a theory-based conceptual framework. Journal of Research in Personality 2008; 42: 1285-302. ## [DOI:10.1016/j.jrp.2008.04.002]

30. Jacobs TL, Epel ES, Lin J, Blackburn EH, Wolkowitz OM, Bridwell DA, et al. Intensive meditation training, immune cell telomerase activity, and psychological mediators. Psychoneuroendocrinology 2011; 36: 664-81. ## [DOI:10.1016/j.psyneuen.2010.09.010] [PMID]

31. Specht J, Egloff B, Schmukle SC. Stability and change of personality across the life course: The impact of age and major life events on mean-level and rank-order stability of the Big Five. Journal of Personality and Social Psychology 2011; 101: 862-82. ## [DOI:10.1037/a0024950] [PMID]

32. Sutin AR, Zonderman AB, Ferrucci L, Terracciano A. Personality traits and chronic disease: Implications for adult personality development. Journals of Gerontology Series B: Psychological Sciences and Social Sciences 2013; 68(6): 912-20. ## [DOI:10.1093/geronb/gbt036] [PMID] []

Send email to the article author

Add your comments about this article

‎ 10.61186/armaghanj.29.3.386

Mendeley

Zotero

RefWorks

Rezapour M, Bagherzadeh ledari R, Ghorkhanechi R, Ahmad abadi S, Naderisorki M. Investigating The Relationship Between Personality Traits and Iron Overload in Transfusion-Dependent Thalassemia Patients. armaghanj 2024; 29 (3) :386-402
URL: http://armaghanj.yums.ac.ir/article-1-3556-en.html

Rights and permissions
	This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Volume 29, Issue 3 (4-2024)

Back to browse issues page

Persian site map - English site map - Created in 0.06 seconds with 37 queries by YEKTAWEB 4700