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Background & aim:  Acute respiratory disease caused by the new coronavirus (COVID-19), which was identified in December 2019, is rapidly progressing and spreading in the world and has been identified by the World Health Organization as a major global threat. Therefore, the aim of this study was to determine and investigate the relationship between underlying diseases and hospitalization in intensive care units in patients with Covid-19 in Yasuj.
 
Methods: Among the patients referred to the infectious department of Shahid Jalil Hospital in Yasuj, 48 real positive patients were selected based on clinical diagnostic tests (RT. PCR diagnostic test). Determination of underlying diseases was based on self-declaration during the questionnaire as well as patients' clinical history.
 
Results: Of the 48 patients admitted with COVID-19, 46% (23 patients) were reported to be patients with underlying disease, of which 20.83% were related to hypertension, 12.5% to diabetes, and 8.33% to ischemic heart disease (IDH), 4.34% had chronic obstructive pulmonary disease (COPD) and 2% had nominal disease. 20% of patients were admitted to the ICU. There was also a positive and significant relationship between hypertension, diabetes, myocardial ischemia and ICU admission.
 
Conclusion: Patients with any underlying disease had poorer clinical outcomes than those without the disease. More underlying diseases are also associated with poorer clinical outcomes and the need for hospitalization in the ICU.