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Introduction & Objective: Coronary arteries diseases and atherosclerosis are the most prevalent mortality and morbidity in the world. This study was designed with goal of effect of frankincense extract on accumulation of fatty streaks in coronary arteries of high- cholesterol fed male rabbits. Materials & Methods: Twenty white male rabbits (wt = 1.780 kg) were weighed and blood samples were taken for analysis of serum cholesterol, TG, LDL, HDL, VLDL. After taking the sample rabbits were randomly divided into two groups. For 40 days group 1 (n=10) was given high cholesterol (1%) diet with frankincense extract (500 mg/kg) and group 2 (n=10) were fed with high cholesterol with distilled water. Then, both groups weighted and blood samples were taken. Finally, the animals were sacrificed and their coronary arteries were dissected. Pathological smear were prepared and stained with H&E. The plaque of atherosclerotic was evaluated by light microscope. Results: Results of this study indicate that rabbits which received frankincense extract showed significant difference in cholesterol, TG, LDL, HDL, VLDL in compare with other group (p < 0.05). Also, our results showed a significant difference in mean of pathological scoring of four branch of coronary arteries (p < 0.05). Conclusion: Significant differences in all of parameters such as weight, serum cholesterol, TG, HDL, LDL, VLDL might be related to effect of frankincense extract on lipid metabolism. Pathological results showed that frankincense extract could decrease accumulation of fatty streaks in all branches of coronary arteries. Thus frankincense extract can be for preventing of used cardiovascular diseases, atherosclerosis and for treatment of lipidemia

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ABSTRACT: Introduction & Objective: Breast cancer is one of the most prevalent cancers among the women with annual growth of 2 percent. It affects grossly the patient's quality of life. Rehabilitation can be so effective on physiopsychosocical health and finally increases their quality of life recovery. This study was designed to determine the effects of rehabilitation on quality of life in women after mastectomy. Materials & Methods: In a clinical trial, 57 cancerous women who underwent modified radical mastectomy, had finished chemotherapy and radiotherapy and received hormone therapy were selected and randomly placed in two case and control groups. Control group was under medical care and the case group in addition to medical care received rehabilitation (physiotherapy, education, individual counseling) for 2 months. The quality of life, with regard to breast cancer, was measured by EORTC QLQ-BR 23, before Intervention, 1 week and 3 months after rehabilitation in both groups. Data analysis was done by chi square, fisher exact test, t- and paired t-tests and repeated measurement test. Results: There was a statistically significant decrease in body image and future perspective and meaningful increase in sexual enjoyment and arm symptom in case group compared to control group before intervention, while no significant difference was seen in other scales before intervention. One week after the interference, differences of both group in two scales of sex function and sex enjoyment were meaningful and the function of case group was more undesirable then that of the control group. Three months after completing the process there was a meaningful decrease in sex function and sex enjoyment in case group in comparison with the control group but there was a significant recovery in the case group in other performance scales. Systemic therapy side effects were significantly decreased in case group 3 months after intervention whereas the quality of life in control group decreased or did not change significantly after 3 months. Conclusion: Performing rehabilitation process including education, individual counseling and physiotherapy can promote the Q.O.L of patients with mastectomy therefore rehabilitation can be recommended as an effective care program.

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Back ground & aim: In the recent years, the increasing use of electronic devices which generate electromagnetic fields, focused researchers’ attention to investigate the electromagnetic fields effects on human health. Therefore, the purpose of the present study was to investigate the effect of prolonged exposure to extremely low frequency electromagnetic fields (ELF) on the adrenergic system in the small intestine of male rats.

Methods: In the present experimental study, 21 Adult male rats (wistar) were divided into three groups: experimental group, which were exposed to ELF (50Hz, 1mT) for 75 days, the sham-operated group, which were kept in similar conditions exception Off solenoid and the control group, which were kept in normal conditions. After 75 days, the rats were anesthetized by intra peritoneal injection of pentobarbital sodium (50 mg/k). Then, the ileum tissue was dissected and divided into 1 cm strips. The strips were placed in organ baths containing oxygenated, pH=7.4 Krebs solution. Furthermore, the mechanical activity of the tissue was recorded with force transducer of bridge amplifier which was linked to A-D Instrument power lab in response to Phenylephrine(4 ×10^{-6 M). Data was analyzed using one way ANOVA test.}

Results: Relaxation changes of isolated ileum tissue was displayed in two ileum strips with same length and in the same animal, According to the obtained results, the ileum relaxation in exposure to ELF (experimental) compared to the control and sham groups significantly increased (p&le0.05). Accordingly, the relaxation changes of ileum in response to the phenylephrine at different times and after deducting the basic tension represented a significant increase (p&le0.05) of Ileum relaxation in the experimental group compared to the sham and control groups.

Conclusion: It can be concluded that prolonged exposure to extremely low-frequency electromagnetic fields may lead to increase of  the &alpha₁-adrenergic receptors sensitivity.