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Showing 4 results for Eftekhar

Z Eftekhar , F Yarandi, M Tahmasbi,
Volume 9, Issue 1 (4-2004)
Abstract

ABSTRACT Introduction & Objective: Ovarian hyperstimulation syndrome has been described after treatment with exogenous gonadotropins, clomiphen citrate and GuRh,s, but spontaneous form of this syndrome is very rare. This is a case report of spontaneous ovarian hyperstimulation syndrome associated with a case of spontaneous pregnancy and ovarian torsion. Case: The patient was a 30-year –old woman who was admitted due to abdominal pain from 1 week ago at 11 weeks gestation .In physical examination her abdomen was severely distended and diffusely tender and both ovaries were enlarged about 15 cm each and were tender. Ultrasonography revealed a single alive intrauterine fetus, 10 weeks gestation, with bilateral multilocular ovarian cysts with smooth surfaces and clear contents. Laboratory results showed low albumin and elevated CA125 (295 U/ml). She received 100g albumin and due to dyspnea a paracentesis was done. After 2 weeks she was readmitted with a complaint of right lower quadrant pain and tenderness and underwent laparotomy with diagnosis of right ovarian torsion. The ovary untwisted and several large cysts were aspirated. She had a normal vaginal delivery of a normal healthy female infant weighing 3100g at 40 week's gestation. Conclusion: Ovarian torsion and rupture should be considered in these patients. If surgery needed , untwisting of ovarian even if it is chemic and contron of bleeding seems to be enough.
M Nazari , A Heidarnia , H Eftekhar Ardebili , M Mobasheri , F Amin Shokravi , Sh Niknami , G Babaei ,
Volume 13, Issue 2 (7-2008)
Abstract

Introduction & Objective: Pedestrian injuries are a significant source of morbidity, mortality and disability among children. Prevention of these injuries is thus a major priority for public health and requires a comprehensive approach and educational strategies. The purpose of this study was designing and evaluation of an educational program, based on the PRECEED-PROCEED model for improvement of safety behavior in primary school boys. Materials & Methods: This study is a field trial carried out in 6th areas of Tehran in 2007. Participants (n=88) were 10 – 11 year old who followed by items measuring the PRECEED-PROCEED model before and after two months of intervention. The collected data were analyzed with T test, X2 and pair T test using SPSS software. Results: After participating in educational program, significant improvements were found in knowledge, attitude, behavior, enabling and reinforcing factors of the components of PRECEEDPROCEED model. Conclusion: The findings suggest the beneficial effects of educational intervention based on the PRECEDE-PROCEED model on improving the safety behavior. It can be recommended that health education plan be used on educational models.
R Ostovar , A Pourreza , A Rashidian, S Mehrabi, Ar Mehrsay, M Mahmoodi, H Eftekhar Ardabili, Gh Poormand ,
Volume 14, Issue 2 (7-2009)
Abstract

ABSTRACT: Introduction & Objective: Results of different studies show that a relatively large number of healthcare services offered are inappropriate or unnecessary. Benign prostatic hyperplasia is a benign enlargement of the prostate gland. Clinical features of this disease are one of the most common problems encountered by elderly males. The aim of this study was to assess the appropriateness of benign prostatic hyperplasia surgery. Materials & Methods: In this qualitative study which was conducted in 2008-9, in Tehran University of Medical Sciences, the RAN/UCLA method was used, which was designed in 1980 by the RAND institute and the University of California in Los Angeles. Regarding the stages of our method, scenarios and indications for benign prostatic hyperplasia surgery were chosen from the latest approved scientific resources and subsequently sent to urology specialists, who were chosen as members of the specialized panel. Panel members gave scores ranging from 1 to 9 to each indication and scenario based on scientific resources, clinical experiences and patient’s condition in two separate panel sessions. After compilation, the indications were finally grouped as appropriate, equivocal, and inappropriate so that they could be used to determine appropriateness of benign prostatic hyperplasia surgery in hospitals. In this study, the most suitable and most approved clinical guidelines related to benign prostatic hyperplasia, the Guidelines Evaluation and Research Appraisal (AGREE) were used.The selected guidelines were used as scientific resources for choosing the indications of benign prostatic hyperplasia surgery. SPSS version 16 and kappa weighted value were used in analysis process of the study. Results: Out of 282 scenarios grouped as 9 conditions related to benign prostatic hyperplasia surgery, which were extracted from scientific sources, 73 cases (25.9%) were considered as appropriate, 14 cases (5%) as equivocal and 7 cases (2.5%) were considered as inappropriate. Also 22 cases (7.8%) were considered as appropriate indications for drug therapy and none were found to be suitable for waiting and watching. There were 94 scenarios related to surgery that 75 scenarios (80%) were grouped in appropriate and 8 scenarios (8.5%) identified inappropriate. Conclusion: At the present time, due to the lack of scientific evidence for suitable decision-making in providing health services, methods based upon agreement, including the one used in the present study, and the use of treatment standards derived from similar studies, are amongst the most important measures taken to improve the standard of health, provide suitable health services, and to reduce unnecessary costs. In addition, RAM appropriateness method could be an ideal method in determining the appropriateness of health care and in reducing the rate of inappropriate services provided. The similarity of results derived from other studies performed by the RAND method in determining the appropriateness of benign prostatic hyperplasia treatment with the current study shows the validity and reliability of this method. Keywords: Appropriate criteria, Benign Prostatic Hyperplasia (BPH), Appraisal of Guidelines for Research and Evaluation (AGREE).
H Vaghefi Eftekhar, V Sheibani , A Mohammadi Pour, A Aboli,
Volume 16, Issue 6 (2-2012)
Abstract

Background & Aim: There are multiple processes that lead to cell death after brain ischemia, such as glutamate release and inflammatory reactions. Histamine is able to suppress inflammatory reactions and glutamate release. Since histidine is precursor of histamine, this study was conducted to evaluate its neuroprotective effects on CA1 region of rat hippocampus following brain ischemia. Methods: In the present experimental study, thirty-six male Wistar rats were randomly divided into six groups as the following: control, surgical control, ischemia, and three groups which different doses (200, 500, and 1000 mg/kg) of histidine. Focal cerebral ischemia, for 60 min, was provoked by transient occlusion of the right middle cerebral artery in all groups except the two control groups, and histidine neuro-protective effects on neuronal death was evaluated in CA1 of hippocampus neurons after 7 days. The gathered data was analyzed using one-way ANOVA. Results: The results showed that the mean number of neuronal degeneration and pancellular necrosis in groups which received doses of 500 and 1000 mg/kg of histidine have significantly decreased in comparison with the ischemia group (p=0.001). This reduction in dose of 200 mg/kg of histidine was not statistically significant (p=0.05). Conclusion: Our present findings show that intraperitoneal administration of histidine before reperfusion alleviated CA1 damage.

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