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:: Volume 20, Issue 7 (10-2015) ::
__Armaghane Danesh__ 2015, 20(7): 549-557 Back to browse issues page
The effect of intravenous aminophylline on stone free status after transureteral lithotripsy (TUL): a randomized double blind clinical trial study
A Barzegarnezhad 1, SA Emadi2, A Firouzian2, R Sharifian3, M Daneshian2, M Montazami2
1- 1Department of Urology and Renal Ransplantation, Mazandaran University of Medical Science, Sari, Iran , ayubbarzgarnejad@gmail.com
2- 2Department of Anesthesiology, Mazandaran University of Medical Science, Sari, Iran.
3- 1Department of Urology and Renal Ransplantation, Mazandaran University of Medical Science, Sari, Iran
Abstract:   (5176 Views)

Background: The third common urinary tract disease was renal stone, after the UTI and pathologic states of kidney. TUL is most useful and effective for removing the stones of inferior ureter. In other hand aminophylline can decrease urinary tract spasm. Then, combination of TUL and aminophylline help us to reduce the complication of TUL. Methods and materials: We have study on 87 case of renal colic who referred to Imam Khomeini hospital of sari and Tooba clinic. This study was a double blind systematic randomized clinical trial that patients were divided to two group as 1 and 2: group one includes patients who received aminophylline and group 2 were selected as our control samples. Our sample size was calculated by statistic analysis according to recent studies. Result: The average of TUL time was 5.12± 1.77 min in group 1 and 6.59± 3.47 min in group 2(p<0.05) and the success percents of TUL was 97.6% in group 1 and 84% in group 2(p>0.05). ESWL was used in one patient of group 1 because of remaining of stone, but 7 patients of group 2 did not response to Transureter lithotripsy, then they needed ESWL. Complication were not seen in patient who received Aminophylline and mean arterial pressure and heart rate was equal in two group. Conclusion: The difference of TUL Time between two groups was meaningful. As you know, aminophylline has an antispasmotic effect on urinary tract and tract with smooth muscle, and according to our finding, usage of aminophylline can reduce the complication of TUL and increase success rate of Lithotripsy in this patient. In other hand, it complications was few.

Keywords: Kidney stone- aminophylline- lithotripsy
Full-Text [PDF 144 kb]   (834 Downloads)    
Type of Study: Research | Subject: Special
Received: 2015/01/31 | Accepted: 2015/08/8 | Published: 2015/09/2
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barzegarnezhad A, emadi S, firouzian A, sharifian R, daneshian M, montazami M. The effect of intravenous aminophylline on stone free status after transureteral lithotripsy (TUL): a randomized double blind clinical trial study. Armaghane danesh. 2015; 20 (7) :549-557
URL: http://armaghanj.yums.ac.ir/article-1-43-en.html


Volume 20, Issue 7 (10-2015) Back to browse issues page
ارمغان دانش Armaghane danesh
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