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Comparative Efficacy of 10% Sodium Sulfacetamide Lotion and 1% Clotrimazole Lotion in Treatment of Tinea versicolor
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F Rad   1, E Ghaderi |
| 1- , dr_farokh_rad@yahoo.com |
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Abstract: (6891 Views) |
| ABSTRACT:
Introduction & Objective: Tinea versicolor is a common superficial fungal infection caused by normal skin flora and many topical and oral anti-fungal medications have been used for its treatment. The aim of this study was to compare the therapeutic effects of 10% sodium sulfacetamide lotion with 1% clotrimazole lotion in treatment of tinea versicolor.
Materials & Methods: In this single-blind clinical trial 67 patients were divided into two groups using block randomization method. The first group consisted of 33 patients who were treated with 1% clotrimazole lotion. The second group included 34 patients who received 10% sodium sulfacetamide lotion. After 2 weeks of treatment, both groups were evaluated for clinical and paraclinical responses. The collected data were recorded in a data sheet and analyzed by X2 and independent T tests, using SPSS software.
Results: After 2 weeks of treatment, clinical and paraclinical responses were seen in 22 patients (66.7%) and 28 patients (84.8%) in the first group (clotrimazole lotion) and in 7 (20.6%) and 8 (23.5%) patients of the second group (sodium sulfacetamide lotion), respectively. Statistical analysis showed that the differences are significant.
Conclusion: The therapeutic effect of 10% sodium sulfacetamide lotion is much less than that of 1% clotrimazole lotion in treatment of tinea versicolor. |
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| Keywords: KEYWORDS:Tinea versicolor, Clotrimazole Lotion 1%, Sodium Sulfacetamide Lotion 10% |
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Full-Text [PDF 106 kb]
(1232 Downloads)
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Type of Study: Research |
Subject:
Special
Received: 2015/06/1 | Accepted: 2015/06/1 | Published: 2015/06/1
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