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Effect of KTP Laser Made byAEOI on Resected Prostateafter Open Prostatectomy
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MR Razzaghi   , M Mohammad hosseini , AR Rezaei 1, I Rezaei , S.H Nicknam , B Javanmard |
| 1- , laser.cntr@gmail.com |
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Abstract: (4585 Views) |
| Introduction & Objective: Transurethral resection of prostate
(TURP) is the operation most frequently performed in urology. In
view of the morbidity associated with this procedure, research has
been conducted to propose an endoscopic alternative to TURP.
Using of high energy laser is the most promising method in these
cases. In this study, we evaluated the effect of home made KTP
laser on re-sected prostate adenoma after open prostatectomy.
Materials & Methods: 40 patients complaining of symptomatic
BPH were treated by open prostatectomy. These 40 prostates
were divided in to two parts. One part was sent for pathology
assessment (group A) and the other part was sent to KTP laser
room in the same hospital (group B). The prostates in group B
were divided into 4 groups (1, 2, 3, 4), each with 10 prostate tissue.
In groups 1, 2, 3 and 4, prostate lobes underwent laser ablation in
one, two three and four stage. In any stage, KTP laser, 5 watts for
15 seconds, was used. All of prostate ablated with laser were sent
to pathology for evaluation of tissue ablation capacity and deep
tissue penetration. The study in all of stages was blinded for
pathologist.
Results: Mean age of participants was 73.25±6.8 years and mean
level of PSA was 3.65±2.1 ng/dl. In both groups, with every stage
laser, we have 1 to 2 mm tissue ablation associated with prostate
type. In pathologic examination, we have 0-2 mm tissue
destruction with disappearance of cells' nuclei, basophilia of
stroma and damaged tissue (cutter like effect). Findings were
compatible with burn effect.
Conclusion: Pathologic findings proved, in the ex vivo
investigation, that KTP laser offers a good tissue ablation capacity
and minimal microscopic tissue damage. The risk of capsule
perforation is very low. This procedure is safe and effective in
which bladder outlet obstruction symptoms will be quickly relieves
and has a low rate of complications. Moreover KTP laser has much
cost effectiveness, although we need further studies on live
prostatic tissues |
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| Keywords: Benign Prostatic Hyperplasia (BPH) |
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Full-Text [PDF 262 kb]
(1248 Downloads)
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Type of Study: Research |
Subject:
Special
Received: 2015/06/1 | Accepted: 2015/06/1 | Published: 2015/06/1
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