Introduction & Objective: Due to emergence of resistance of antibiotics to microorganisms, investigations for novel antimicrobial agents have always been one of the major preoccupations of the medical societies. The present investigation aimed to study the antimicrobial properties of Plantago psyllium on some of pathogen microorganisms.
Materials & Methods: This experimental study was carried out at Yasouj University of Medical Sciences in 2010.
After collection and preparation of hydroalcoholic extract of Plantago psyllium, its effects against human pathogen microorganism (overall 10 microorganisms) were evaluated. Minimal Inhibitory Concentration (MIC) and minimum lethal concentration were determined for this extract.
The antimicrobial effect of Plantago psyllium extract with commercial antimicrobial agents were compared. Collected data were analyzed by SPSS software using one-way ANOVA and chi-square test.
Results: Findings of the present study revealed that in l0 mg/ml and 20 mg/ml concentrations of the extract, all bacteria were resistant to Plantago psyllium. In 40 mg/ml concentration, only Staphylococcus areus and staphylococcus epidemidis showed zone of inhibition (ZOI) of 10 mm and 13 mm respectively while in 80 mg/ml concentration, the maximum ZOI was 20 mm in Staphylococcus areus and 18 mm in staphylococcus epidemidis. The acceptable MIC and MLC were 40 mg/ml and 80 mg/ml in Staphylococcus areus and staphylococcus epidemidis respectively.
Conclusion: Our data clearly indicated that the extract displayed equivalent compatibility with standard antibiotics on Staphylococcus areus and staphylococcus epidemidis bacteria.