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Comparing the Efficacy and Adverse Effects of Tramadol and Sodum Diclofenac with pethedine in the Treatment of Renal Colic
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M Rajaei   , K Noorian 1, Madineh , S Madineh |
| 1- , noorian@skums.ac.ir |
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Abstract: (7606 Views) |
| Abstract
Background & aim: One of the choice treatments for pain relief in acute renal colic is administration of narcotics, but always the need for low-dose effects are felt difficulties. The aim of this study was to compare the efficacy of sodium diclofenac and pethedine hydrochloride with Tramadol to reduce the pain of acute renal colic.
Methods: In this clinical trial study, 150 patients (15-65 years) with acute renal colic referred to Kashani hospital in Shahrekord were selected. The patients were randomly divided into 3 groups. The first group received 50mg tramadol intramuscular, the second group received 75mg D sodum iclofenac intramuscular and the third group (the evidence group) received 50 mg pethidin intramuscular. The pain severity was assessed before and then at 15, 30,60minutes after drug administration based on the McGill questionnaire. Data were analyzed with chi-square tests, ANOVA and Kruskal-Wallis tests. The pain severity of all parties on arrival to emergency ward and prior to the drug administration, and then 15, 30 and 60 min after the start of treatment were measured using a modified McGill questionnaire.
Results: After drug administration (30.15 and 60 min), pain severity were decreased in all three groups. Minimum pain was seen in control where as the maximum pain was seen in tramadol group. Diclofenac have less side effects than pethedine (P<0.05).
Conclusion: The finding showed that intramuscular Na Diclofenac due to its less adverse effects and more efficacy than tramadol is a suitable alternative to pethedine in treatment of acute renal colic.
Key words: Pethedine, Tramadol, Diclofenac Na, Renal Colic |
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| Keywords: Key words: Pethedine, Tramadol, Diclofenac Na, Renal Colic |
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Full-Text [PDF 437 kb]
(3889 Downloads)
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Type of Study: Research |
Subject:
Special
Received: 2015/04/28 | Accepted: 2015/04/28 | Published: 2015/04/28
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