2024-03-28T15:50:03+03:30 http://armaghanj.yums.ac.ir/browse.php?mag_id=98&slc_lang=en&sid=1
98-1779 2024-03-28 10.1002
Armaghane Danesh armaghanj 1728-6506 1728-6514 10.61186/armaghanj 2017 22 4 Study of Nigella sativa L. seed’s hydroethanolic extract on skin wound healing in male diabetic rats E Noorbar elhamnorbar909@yahoo.com N Mirazi Mirazi205@gmail.com Abstract Background and Aim: Skin wounds are a common complication of diabetes. The use of herbal medicines has had a beneficial effect on healing of the wound. The aim of this study was to evaluate the effect of hydrotanol black currant extract on skin ulcers in diabetic rats. Methods: The current experimental study was performed on 49 male Wistar rats (weighing 250-220 gr) in 7 equal groups. Healthy, untreated, healthy subjects received 1% phenytoin, healthy treated with aspirin (sham), untreated diabetic, diabetic groups (receiving 1% phenytoin, 20% and 40% hydrotagonal extract of blackcurrant). Diabetes was induced by Streptozotocin (60 mg / kg). After anesthesia, injuries were made in the 1 × 2 cm area at the back of each animal, and each group received the treatment for their entire healing until complete healing. Histological studies were performed on tissue samples. The area of ​​the wound was measured every three days once, and the data were analyzed by one-way ANOVA and Tukey's post hoc test. Results: The mean wound healing time for non-treated diabetic groups and phenytoin-treated diabetics was 27 and 24 days, respectively. In healthy groups without treatment, the healthy phine thyinea hemorrhage was completed on days 23, 24 and 21, respectively. The shortest healing time was observed in diabetic groups treated with 20% (18 days) and 40% (15 days) black currant extracts. The two groups also had the lowest mean surface area of ​​the wound during the study period and the mean of the wound levels of the treated groups with the black yeast extract was significantly different from the control group (p<0.05). Conclusion: The extract of black currant has significant effects on the healing process of wounds in rats. Regarding the anti-inflammatory and anti-microbial properties of black cumin, it can be used to repair skin lesions. The antioxidant material in this plant accelerates the process of wound healing in comparison with conventional drugs.   Blackheads Skin ulcer Diabetes mellitus Rat 2017 10 01 419 430 http://armaghanj.yums.ac.ir/article-1-1779-en.pdf
98-1866 2024-03-28 10.1002
Armaghane Danesh armaghanj 1728-6506 1728-6514 10.61186/armaghanj 2017 22 4 Comparison of Antinociceptive Effect of Viola Odorata with Carbamazepine in Animal Seizure Model M Modaresi mehrdad_modaresi@hotmail.com F Ghorbali mm13822000@hotmail.com I Sajjadian mehrdadmdrs@gmail.com Background and Aim: Currently, various drugs are used to treat epilepsy and seizures, which in turn, have side effects and, in the long run, cause drug resistance. In traditional medicine, violet plant (Viola odorata) is recommended for the treatment of seizure. The aim of this study was to evaluate the antinociceptive effects of violet flowers in animal models of seizure compared to carbamazepine. Methods: In the present experimental study, 40 rat mice were used in five groups of eight. Hydroalcoholic extract of violet flower was diluted with physiological serum. Experimental groups included: control group and four treatment groups receiving carbamazepine and extract of violet flowers at doses of 50, 100 and 200 mg / kg by intraperitoneal method one hour before injection of pentylenetetrazole. Subsequently, non-response factors of the animal, duration of tonic seizure, clonic seizure, generalized seizure, total seizure and mortality rate was determined.  Data were analyzed using multivariate and one-way ANOVA using statistical package for social sciences version 22 and chi-square test. Results: Violet flower extract at dose of 50 mg / kg was significantly different in the tonic-clonic stage and at the time of total seizure in the control group. However, there was a significant difference in the injections of 100 and 200 mg / kg in all stages with the control group (p <0.05). The mortality rate in the 200 mg / kg dose of vinegar extract was significantly lower than other experimental groups. Conclusion: The hydroalcoholic extract of violet flowers in at dose of 200 mg / kg was proposed as an effective and effective drug in the prevention of seizure in the animal model.       Convulsion Viola Carbamazepine Pentylenetetrazol (PTZ) Mice 2017 10 01 431 441 http://armaghanj.yums.ac.ir/article-1-1866-en.pdf
98-1732 2024-03-28 10.1002
Armaghane Danesh armaghanj 1728-6506 1728-6514 10.61186/armaghanj 2017 22 4 The Effect of Eight Weeks of Aerobic Training and Complementary Plant Supplements (Indian Valerian and Melissa Officinalis) on Migraine Z Eskandari zohreh.eskandar8@gmail.com B Mirzaei bmirzaei2000@yahoo.com H Arazi hamidarazi@yahoo.com Abstract Background and Aim: Migraine is a debilitating disease that causes pain and suffering to patients. The purpose of the present study was to investigate the effect of eight weeks of aerobic and complementary exercise on headache indices including the frequency, duration and severity of headache, and the number of synthetic drugs used and signs of depression and anxiety. Methods: The present study was a quasi-experimental and applied research. Twenty-four patients with migraine who were eligible to participate in this study were randomly assigned into two groups of aerobic training (12) and a group receiving combined plant supplement (12). The aerobic training group's exercise program was performed for eight weeks and weekly three sessions and each session included 75 minutes of aerobic activity (15 minutes of warming, 45 minutes of workout, 15 minutes of cooling) with moderate intensity. The combined herbal supplement group consumed eight weeks of herbal capsules; each capsule contained 200 mg valeriana and 80 mg of melissa, which was given twice daily in the first four weeks and in the second four weeks three times daily. Headache indices and the number of synthetic drugs consumed by the headache questionnaire were evaluated and Beck's anxiety and depression questionnaire was used for anxiety and depression symptoms. The collected data were analyzed using independent t-test and t-test. Results: In the combined supplemental group of two plants, the consumption of eight weeks of herbal capsule significantly reduced the number of headache / headache days, headache severity, depression scores and the number of synthetic drugs used (p <0.05). Anxiety scores decreased, but were not significant. In addition, the duration of the headache was not different from the one before the study. In the aerobic training group, eight weeks of activity significantly reduced in the number of headache / headache days, headache severity, anxiety and depression symptoms, and the number of synthetic drugs used, but the duration of the headache did not change. Also, by comparing variables of headache, anxiety and depression indices between the two groups, these variables were similar in the baseline and end of the study, and there was no significant difference between them.   Conclusion: Aerobic and complementary aerobic exercises could be considered as an alternative treatment for patients with migraine who cannot tolerate nor benefit from synthetic drugs.     Migraine Aerobic training Hyacinth Melissa officinalis 2017 10 01 442 458 http://armaghanj.yums.ac.ir/article-1-1732-en.pdf
98-1820 2024-03-28 10.1002
Armaghane Danesh armaghanj 1728-6506 1728-6514 10.61186/armaghanj 2017 22 4 Biosynthesis of Silver Nanoparticles Using Oscillatoria Extract and Evaluation the Anticancer and Antibacterial Activities T Ghasemipour mashhad200795@gmail.com A Salehzadeh salehzadehmb@yahoo.com SA S adat Shandiz atashandiz@yahoo.com Abstract Background and aim: The emergence of nanotechnology is one of the most promising areas for medical research. Today, biological methods of synthesizing nanoparticles have been considered in the fight against many diseases. The purpose of this study was to evaluate the anti-cancer and anti-bacterial activity of silver nanoparticles, biosynthesized with cyanobacteria acetate extract. Methods: In the present experimental study, the silver nanoparticles biosynthesis was performed using silver ions regeneration with cyanobacteria acetate extracts. Techniques such as X-ray diffraction, scanning electron microscopy and transient evaluation of silver nanoparticles were evaluated. In order to investigate the antibacterial activity of synthesized nanosilver, serial dilution method was used for broth microdilution test to determine minimum inhibitory concentration (MIC). The effects of silver nanoparticle toxicity on T47D breast cancer cell line were evaluated using MTT colorimetric method. Also, the proximal anxine 0.5 propidoid yodide kit and flow cytometry system were evaluated to evaluate the percentage of apoptosis and necrosis in cancer cells treated with silver nanoparticles. Results: Characterization of biosynthetic silver nanoparticles indicated that these nanoparticles had a mean size of 30 nm with dominant spherical morphology. The evaluation of the antibacterial properties of biosynthetic nanoparticles showed that the minimum inhibitory concentration for Escherichia coli, Acinetobacter Bumanni and Staphylococcus aureus was 25, 50 and 12.5 μg / ml, respectively. The results of cell proliferation of nanoparticles showed that its effect depends on the concentration and time of treatment of silver nanoparticles on cancerous cells. In addition, flow cytometric results showed an apoptotic cell death rate of 35% in the T47D cell line. Conclusion: Biosynthesis nanoparticles have anticancer and antibacterial activity and can be studied further in the treatment of breast cancer and infections caused by pathogenic bacteria.   Anticancer Apoptosis Osituria Antibacterial 2017 10 01 459 471 http://armaghanj.yums.ac.ir/article-1-1820-en.pdf
98-1486 2024-03-28 10.1002
Armaghane Danesh armaghanj 1728-6506 1728-6514 10.61186/armaghanj 2017 22 4 Investigating the protective factors of positive blood culture in Sepsis M Momen Heravi mansoreheravi@yahoo.com R Razaghi rezarazzaghi33@yahoocom H Afzali hasanafsali@yahoo.com A Tahmourte amintahmoores@yahoo.com Abstract Background and aim: Blood culture is one of the methods of diagnosis of bacterial etiology of sepsis, but because of the low number of organisms in the blood or the use of antibiotics, separation of the organism causing sepsis is difficult in this way. This study was designed to determine the predictive factors for positive blood culture in sepsis patients. Methods: The present historical cohort study was conducted on 320 patients with sepsis who were admitted to Shahid Beheshti Hospital in Kashan from October 2013 to October 2014. By examining patients' records, demographic, clinical and laboratory information including age, sex, hospitalization, temperature, pressure drop, tachycardia, tachypnea, serum CRP (CRP), white blood cell count (WBC), red blood cell sedimentation rate) ESR) and treatment outcomes. Data were analyzed using Chi-square, Mann-Whitney and t-test.   Results: The mean age of patients in the case group was 67.93 ± 12.12 years in the case group (case group) and 64.67 ± 13.87 in the negative control group (control group). Frequency of underlying disease, recent history of admission, hypotension and tachypnea in case group were more than control group. The results of logistic regression analysis indicated that serum reactive protein level, red blood cell dysplasia and white blood cell count are related to the outcome of blood culture in patients with sepsis.   Conclusion: Regarding the relationship between positive blood culture and inflammatory markers, in patients with sepsis, the increased inflammatory markers can be indicative of bacteremia and accelerate the onset of antibiotics and more precision in conducting blood cultures to discover the organism of sepsis.     Sepsis Blood Cultures Predictive Factors 2017 10 01 472 485 http://armaghanj.yums.ac.ir/article-1-1486-en.pdf
98-1756 2024-03-28 10.1002
Armaghane Danesh armaghanj 1728-6506 1728-6514 10.61186/armaghanj 2017 22 4 The effects of hydro-alcoholic extract of Nigella sativa seed on sperm parameters and spermatogenesis in toxicity induced by diazinon in male rats R Ghasemi F Mir Mohammad Rezaei fereshteh.mmrezaei@gmail.com S Nasri s_nasri2000@yahoo.com A Nili Ahmadabadi amirnili54@yahoo.com Abstract Background and aim: Organophosphate insecticide diazinon is used in agriculture and may affect fertility of men due to the production of free radicals. Because of the antioxidant properties of black currant compounds, the effect of hydroalcoholic extract of black currant on spermatogenesis in diazinon-induced toxicity in male rats was investigated. Methods: In the present experimental study, 30 adult male Wistar rats were divided into six groups: control group without sham, corn oil and saline without intervention; the positive control group received Diazinon poison at a concentration of 16 mg / kg. Experimental 1 and 2 respectively received diazinon poison (16 mg / kg) and black and white extract (100 mg / kg) and 200 mg / kg (3 mg / kg) extract, respectively. They received 3 extracts of black currant with a concentration of 200 mg / kg. All treatments were carried out for 2 months in gavage. After 2 months sperm parameters, number, mobility, life and morphology were investigated. Similarly, testicular tissue was stained with Hematoxylin Eosin for evaluation of spermatogenesis after cutting. Data were analyzed by one-way ANOVA and Tukey's post hoc test. Results: Diazinon with a concentration of 16 mg / kg caused a significant decrease in the number and motility of the sperm in comparison to the sham group (p <0.01) (p <0.001), but significantly altered sperm motility and morphology compared to the group Did not have you The group that received diazinon and extract of black currant with two concentrations of 100 and 200 mg / kg compared to diazinon group showed a significant increase in the number of sperms (p <0.01) (p <0.001), but blackheads caused a significant change Sperm motility was not present in the presence of diazinone. Histological examination showed that the number of primary spermatocyte cells and spermatid in the diazinone group compared to sham group decreased significantly (p <0.05). However, the number of spermatogonia cells, primary spermatocytes and spermatid in experimental groups 1 and 2 showed a significant increase compared to diazinon group (p <0.05). In the experimental group 3, the extract increased the number of sperm in comparison with the sham group (p <0.05), but did not change the testicular tissue. Conclusion: The results indicated that black currant extract had a protective effect on testicular tissue and could increase spermatogonia, spermatocyte, spermatid and sperm count in diazinon-induced toxicity but did not affect sperm motility.       Diazinon Nigella sativa Sperm parameters Testis 2017 10 01 486 498 http://armaghanj.yums.ac.ir/article-1-1756-en.pdf
98-1548 2024-03-28 10.1002
Armaghane Danesh armaghanj 1728-6506 1728-6514 10.61186/armaghanj 2017 22 4 The Effectiveness of Collaborative Couple Therapy on Communication Patterns and Intimacy of Couples Referring to Counseling Centers of Behbahan, Iran M Sodani sodani_m @yahoo.com M Shogaeyan mshogaeyan@yahoo.com R Khojastamhr khojasteh_r@scu.ac.ir KH Shiralinia k.shiralinia@scu.ac.ir Abstract Background and Aim: Intimacy is a key characteristic of marital relationships and is one of the most prominent characteristics of a successful marriage. Communication patterns can also determine marital satisfaction. The aim of this study was to determine the effectiveness of coupled collaborative therapy on communication patterns and intimacy of couples referring to Behbahan counseling centers. Methods: In this research, a single-trial experimental design, which was also called a single-trial trial, was used as a clinical trial. This design has different types. In the present study, several asynchronous base lines were used. Contrary to large-scale group comparison schemes, this design focuses on individual levels, not on average differences in pre-test and post-test. Another point of this plan is that fewer subjects are needed and couples completed the intimate questionnaire and communication patterns on the baseline, treatment and follow-up. Purposeful sampling was voluntary. The population of the study consisted of all disturbed couples referring to Behbahan psychological clinics. From these couples, 3 couples were selected based on entry and exit criteria. For analyzing the data, visual analysis (chart drawing), clinical significance (the changeover index and normative comparison), as well as the percentage of recovery, have been used. Results: The results indicated that couples experience improvement in intimacy (30.95%) and interactive constructive communication model (47.05%), and in the communication model, the expected return (29.55%) and communication pattern Interactive avoidance (33.64%) showed a decrease. Likewise, data analysis using normative comparison showed that the couples after the treatment did not differ from the couples to the norm. Conclusion: Participatory couples’s therapy may increase the intimacy and constructive communication patterns and decrease the communication patterns of waiting and withdrawal expectations and thus reduce disturbance between couples.   Intimacy Communication Patterns Participatory Therapy Couples 2017 10 01 499 514 http://armaghanj.yums.ac.ir/article-1-1548-en.pdf
98-1845 2024-03-28 10.1002
Armaghane Danesh armaghanj 1728-6506 1728-6514 10.61186/armaghanj 2017 22 4 Protective Effect of Curcumin Supplementation and Light Resistance Exercises on Superoxide Dismutase Enzyme Activity and Malondialdehyde Levels in a Severe Endurance Training Period in Male Wistar Rats A Gorzi aligorzi1982@gmail.com F Hosseini farzaneh_soofi@yahoo.com A Azad Azad@znu.ac.ir Abstract Background and aim: Extreme endurance exercises lead to oxidative stress in athletes. Therefore, the purpose of this study was to investigate the effect of curcumin supplement supplementation and light resistance training on the activity of SOD and MDA levels of male Wistar rats during a 8-week endurance training. Methods: In the present experimental study, 36 male Wistar rats were randomly assigned into one of six control groups, curcumin, endurance training, exercise, after one week of information (age 9 weeks and weight 255.62 ± 19.69 grams). Endurance + resistance, endurance training + curcumin and endurance training + curcumin + resistance. Incremental endurance training (8 weeks, 5 sessions per week) was performed on a special treadmill. Speed ​​and running time in the last week reached 35 m / min and 70 minutes. Resistance training (8 weeks, 2 sessions per week) was performed on vertical ladder by closing the rat's weight to the tail. Rats received supplemental curcumin by intraperitoneal injection (8 weeks, 3 sessions per week, 30 mg / kg body weight). SOD activity of the muscle was measured using ELISA kits and serum MDA levels using Tobartic acid (TBARS) method. Data were analyzed using one-way ANOVA (ANOVA).   Results: The antioxidant enzyme activity of SOD in the endometrial muscle of endurance group (1.08 ± 0.222 μg / ml) was significantly lower than control group (22.2 ± 0.481 kg) (P = 0.043), and SOD activity in the endurance + resistance group (1.87 ± 0.172, p = 0.44), endurance + curcumin (2.24 ± 0.222; P = 0.039), and endurance + curcumin + resistance (0.202 ± 0.15, p = 0.029) was significantly higher than endurance group. The levels of malondialdehyde in the endurance group (4.27 ± 0.438 nmol / ml protein) were significantly higher in comparison with the control group (3.42 ± 0.350) (0.331) and Also, serum MDA levels in endurance + resistance groups (± 3.03 ± 0.342, p = 0.003), endurance + curcumin (p = 0.001, p <0.001), and endurance + curcumin + Resistance (3.32 ± 0.349, p = 0.008) was significantly lower than endurance group. Conclusion: According to the findings, curcumin supplementation and light resistance training alone (curcumin: SOD increased by 35% and MDA decreased by 50%, resistance training: SOD increased by 18% and MDA decreased by 40%) And the combination of these (SOD 39% increase and MDA 30% reduction) prevents severe oxidative stress caused by endurance training. Therefore, it is advisable for athletes who use endurance training in their practice programs to use these two supplements.     Extreme endurance training resistance training antioxidant capacity oxidative stress curcumin. 2017 10 01 515 528 http://armaghanj.yums.ac.ir/article-1-1845-en.pdf
98-1790 2024-03-28 10.1002
Armaghane Danesh armaghanj 1728-6506 1728-6514 10.61186/armaghanj 2017 22 4 Relationship between Personality Traits and Psychological Well-Being with Respect to the Mediating Role of Forgiveness A Taghvaininia : taghvaei.ali2@gmail.com A Mirzaei : taghvaei.ali2@gmail.com Abstract: Background and aim: Psychological well-being has been raised in the field of positive psychology and has focused on mental health from an individual's growth and efficiency angle rather than being patient. Identifying the personality building of individuals and adopting appropriate patterns is also of considerable importance. The purpose of this study was to investigate the relationship between personality traits and psychological well-being with mediation as the role of forgiveness. Methods: The present research was a descriptive and causal correlation study. The statistical population consisted of all students of Yasuj University, among which 301 students (171 girls, 130 boys) were selected by multi-stage random sampling. The instruments used were Reiff Psychological Well-being Questionnaire (PVBS), NEO Personality Questionnaire (NEO) and Hartland Forgiveness Questionnaire (HFS). Data were analyzed using Pearson correlation coefficient and structural equation modeling (SEM). Results: The results showed that there was a significant relationship between personality traits (extraversion = p <0.01, r = 0.32), agreement (p <0.01), r = 0.33, openness to experience (p <0.01), and conscientiousness There was a positive and significant relationship between psychological well-being and psychological well-being (r = 0.41, r = 0.41, r = 0.41, r = 0.41). Also, the results showed that the relationship between forgiveness (forgiveness R = 0.27, r = 0.27, r = 0.27), forgiveness in position (r = 0.20, r = 0.23) was positive and significant with psychological well-being. The results obtained from structural equation modeling also indicated that the path coefficient of features Personality to psychological well-being (β = 0.33) and forgiveness for psychological well-being Β = 258/0 is significant at the level of p≤0.01. Also, the results of indirect relations, the role of forgiveness mediators and the significance of these relationships have been confirmed. Conclusion: Personality traits were directly and indirectly related to forgiveness with psychological well-being. The results of this study have been discussed with respect to previous studies and some of its applications have been discussed.   Personality Traits Forgiveness Psychological Well-Being 2017 10 01 529 541 http://armaghanj.yums.ac.ir/article-1-1790-en.pdf
98-1511 2024-03-28 10.1002
Armaghane Danesh armaghanj 1728-6506 1728-6514 10.61186/armaghanj 2017 22 4 The Relationship between Religiosity, Humor and Type-D Personality with General Health of Patients with Heart Disease A Ghadiri ghadiri1168@gmail.com GH Askarizadeh gh.askarizadeh@uk.ac.ir M Bagheri mbibagheri@yahoo.com Abstract   Introduction: Cardiovascular diseases are the most and common cause of death and debilitation worldwide. Psychological factors compose more than 50 percent of the factors affecting heart diseases. Therefore, this research has been performed aiming to investigate the relationship between religiosity, humor styles and Type- D Personality with general health in the patients with heart disease.   Methods: This study is descriptive of correlation type. The statistical population of this research includes all patients with heart disease is the city of Yazd in the years 2016. The study sample consisted of 210 patients with heart failure who were selected by means of verge criteria and were selected by purposeful sampling and based on the Kerjesy and Morgan tables. Research variables Measurement tools are included Serajzadeh questionnaire with 24 items of religiosity (DS-14), Martin’s 32-items questionnaire of humor (HSQ-R), Denollet’s type D personality questionnaire, and Goldberg28 items General Health Questionnaire (GHQ-28). Data was analyzed Using SPSS and AMOS Statistical softwares and path analysis within the framework of structural modeling.   Results: The results of data analysis showed that there is a positive and significant relationship between the affective religiosity (b=0.08; P<0.05), other component of religiosity Other components of religiosity including religious beliefs, consequential religions and religious rituals do not show a significant relationship with general health (P>0.05). Affiliative humor had positive and significant relationship with general health (b=0.18; P<0.05), While other humor styles, including self-enhancing wit, aggressive humor and selfish wit, do not show a meaningful relationship with general health (P>0.05). Finally, two component of type D personality including social inhibition (b=-0.20; P<0.01), and negative affect (b=-0.28; P<0.01), have a negative and significant relationship with general health.   Conclusion: Base on the result of this research affective religiosity, affiliative humor styles, and Type- D personality are important and affecting risk factors in the general health of patients with heart disease. So, by recognizing such factors, the individuals predisposed to this disease can be identified for preventative measures and helping in treatment.     Religiosity Humor Styles Type- D Personality General Health Patients with Heart Disease 2017 10 01 542 556 http://armaghanj.yums.ac.ir/article-1-1511-en.pdf