2024-03-29T00:06:06+03:30 http://armaghanj.yums.ac.ir/browse.php?mag_id=8&slc_lang=en&sid=1
8-147 2024-03-29 10.1002
Armaghane Danesh armaghanj 1728-6506 1728-6514 10.61186/armaghanj 2015 20 1 The Effect(s) of Vitamin A on Persistent Wheezing after Bronchiolitis in Infants Aged 1-12 Months S Sharafian K Keshavarz Dr_sp_asadi@yahoo.com R Abasi M Zoladl H Asadi S E Bider nami S Kazeroni Z Mohammad Hosseini A Rezakhani Background & aim: Viral bronchiolitis is one of the most common causeS of lower respiratory tract infection and almost responsible for 1-3% of hospitalization among children under one year of age. Post bronchiolitis wheezing is the main risk factor for childhood asthma, and its control can decrease incidence of the disease in future. The purpose of this study was to investigate the effect of vitamin A on persistent wheezing after bronchiolitis. Methods: The present double blind clinical trial was conducted on 84 patients aged 1 to 12 months of age who were admitted in Imam Sajad Hospital of Yasuj from October 2012 to 2013. After viral bronchiolitis diagnosis of patients with history and physical exam, they were divided into two similar groups of control and case randomly. Control group received cold and wet nebulized oxygen and bronchodilator and case group received the same protocol together with 5000 IU/kg Vitamin A intramascularlly. Both groups were examined by the same physician before, one and two weeks after treatment and quality and severity of wheezing was recorded. Data were analyzed by statistical student T – test and chi square test. Results: Intensity and quality of wheezing was similar in both groups before the intervention(85/0 = p=0.858) whereas a significant reduction was observed in the severity of wheezing in the group receiving vitamin A compared with the control group (05/0> p<0.05). Conclusion: A significant decrease was observed in persistent wheezing after intramascular administration of a dose of vitamin A in patients requiring hospitalization due to viral bronchiolitis. Administrating one dose vitamin A intramuscularly in patients who need hospitalization due to bronchiolitis, may decrease post bronchiolitis and persistent wheezing. Vitamin A Post bronchiolitis wheezing Bronchiolitis Infant 2015 4 01 1 10 http://armaghanj.yums.ac.ir/article-1-147-en.pdf
8-141 2024-03-29 10.1002
Armaghane Danesh armaghanj 1728-6506 1728-6514 10.61186/armaghanj 2015 20 1 Effectiveness of Cognitive- behavioral Group Therapy on Insomnia Symptoms in Students A Abollahi mbehnammoghadam@yahoo.com AM Nazar J Hasani M Darharaj A Behnam Moghadam Background & aim: Insomnias is associated with considerable problems in educational, vocational, social and familial performance. The purpose of present research was to investigate the effectiveness of Cognitive-Behavior group therapy on improvement of insomnia symptoms in students. Methods: The present clinical trial study was conducted on twenty-four students who were randomly assigned into two groups of case and the control (n = 12). The experimental group was participated in eight sessions of cognitive behavior therapy, while the control group received no intervention. Research tools include the Pittsburgh Sleep Quality Index and the Insomnia Severity Index that completed by both participants. Data were analyzed using ANOVA, t-test. Results: Analysis of covariance showed that the performance of cognitive behavioral therapy may improve symptoms and reduce the severity of insomnia in the experimental group compared with the control group (p < 0.05). Conclusion: Group cognitive-behavioral therapy is effective on symptoms of insomnia in students. Insomnia Cognitive-Behavioral Therapy Sleep Disorders. 2015 4 01 11 18 http://armaghanj.yums.ac.ir/article-1-141-en.pdf
8-140 2024-03-29 10.1002
Armaghane Danesh armaghanj 1728-6506 1728-6514 10.61186/armaghanj 2015 20 1 Study of damages induced by fungicide propiconazole on testicular tissue and process of spermatogenesis and protective effects of selenium in male Sprague Dawley rat H Mohsenikouchesfehani s.rashidipouya@yahoo.com A Angaji S Rashidipouya P Abdollahi T Govahi Background & aim: Propiconazole is an herbal fungicide which is used as a tropical and systematic drug for fungal infection and also as an agricultural chemical for protection and preservation of fruits, vegetables and grains. The aim of this study was to assess the efficacy of fungicides propiconazol and possible protective effects of selenium on testes tissue. Methods: The present expremental trail study was conducted on forty rats which were divided into ten groups of four including control , sham (solvent of propiconazole, distilled water), solvent of selenium (normal saline) and seven experimental groups : group 1 received 0.5 mg/kg/day of selenium, groups 2,3,4 received three doses of 10,50,75 mg/kg/day of Propiconazole, and groups 5,6,7 received three doses of 10, 50, 75 mg/kg/day of propiconazole with 0.5 mg/kg/day of selenium toevaluate. The administration was done intrapritoneal for two weeks in an alternatively fashion. After determining the level of LH, FSH, Testosterone, sperm was counted by hemocitometer. Data were analyzed by the SPSS software using ANOVA test. Results: No significant differences was observed in the level of hormones in the experimental groups2-7 compared with the control group, but the number of sertoli cells, spermatogonia , primary spermatocyte , spermatid and sperm decreased significantly in comparison with the control group (p<0.05). Conclusion: The decrease in numbers of counted sperm indicates that propiconazole has disrupted the production process of these cells and selenium was unable to improve that. Histopathology Propiconazole Selenium Spermatogenesis 2015 4 01 19 30 http://armaghanj.yums.ac.ir/article-1-140-en.pdf
8-144 2024-03-29 10.1002
Armaghane Danesh armaghanj 1728-6506 1728-6514 10.61186/armaghanj 2015 20 1 Effect of Fruit Heracleum Persicum Extract on Changes in Serum Levels of Sex Hormones in Rats with Polcystic Ovary Syndrome (PCOS) F Alizadeh M Azarnia : azarnia@khu.ac.ir G Mirabolghasemi P Karampoor Abstract Background & aim: Polycystic Ovary Syndrome (PCOS) is one of the most common endocrine disorders which affect 5-7 % of women in their reproductive age. Heracleum persicum (Golpar) contains compounds with anti-inflammatory, antioxidant, and antimitosis properties. The purpose of this study was to evaluate the therapeutic effect of ethanol extracts of Heracleum persicum fruit on polycystic ovary syndrome in rats. Methods: In the present experimental study, thirty rats (200±20gr), were injected with 2 ml of estradiol valerate subcutaneously and six other rats were considered as the control group (intact). Sixty days after injection, the rats were divided into control, sham and experimental groups. The experimental group was treated with 200, 400 and 800 mg/kg BW of of Golpar extract interaperitoneally for ten days. The serum levels of LH, FSH, estradiol and testosterone were measured by ELISA and each serum were analyzed using ANOVA. Results: A significant decrease was seen in serum levels of LH (P< 0.05), estradiol (p< 0.01) and testosterone (p< 0.01) in three experimental groups compared with the control group. Whereas, a significant increase in the mean FSH (p< 0.05) concentrations was observed in the groups receiving high dose. Conclusions: Due to the decreasing effect of Heracleum persicum (Golpar) extract on LH, estradiol and testosterone levels and increasing in FSH level in PCOS rat, it seemed that the Golpar had a therapeutic effect on patients with this disease. Heracleum persicum Polycystic Ovarian Syndrome Sex Hormones 2015 4 01 31 42 http://armaghanj.yums.ac.ir/article-1-144-en.pdf
8-143 2024-03-29 10.1002
Armaghane Danesh armaghanj 1728-6506 1728-6514 10.61186/armaghanj 2015 20 1 A Comparison of Behavioral Inhibition/ Activation System, Type D and Optimism in the Breast Cancer Patients and Healthy Controls A Alipoor M Baradaran : psycho_2000mb@yahoo.com M Alvandi Sarabi Background & aim: Nowadays, the role and importance of psychosocial factors on physical health, as well as the influence of personality characteristics in having psychosomatic diseases such as cancer are of interest to many researchers. In spite of increase in breast cancer in Iran, very few studies have been carried out on risk factors of breast cancer. The aim of this study was to evaluate the comparative Behavioral inhibition / Activation System, type D and optimism in the breast cancer patients and healthy individuals. Methods: In the present casual-comparative study, 190 people (95 Patients and 95 Normal Subjects) were selected in Rasht, Iran. Moreover, the groups were matched for demographic characteristics (age, gender and education). All individuals diagnosed with Breast Cancer and Normal Subjects received a Gary-Wilson Personality Questionnaire, Life Orientation Test and Type D Personality Scale. Collected data were analyzed using multivariate analysis of variance and regression. Results: The findings revealed that there were significant differences between cancer and normal groups in behavioral inhibition/activation system, type D Personality and optimism. In this regard, the Breast Cancer group had higher scores subscales of negative affect, social inhibition, passive avoidance, extinction and fight-flight than normal group. In addition, subscales of approach, active avoidance and optimism in the normal group were more than the Breast Cancer group. Conclusion: The present study supported the role of psychological variables in breast cancer patients which is essential for improving patients’ health and quality of life. Breast Cancer Behavioral Inhibition/Activation System Type D Personality and Optimism. 2015 4 01 43 52 http://armaghanj.yums.ac.ir/article-1-143-en.pdf
8-145 2024-03-29 10.1002
Armaghane Danesh armaghanj 1728-6506 1728-6514 10.61186/armaghanj 2015 20 1 The Effect of Ethanol Extract of Aerial Parts of the Mentha piperita in the Acquisition, Tolerance Expression and Dependence to Morphine in Adult Male Mice N Khajeh A Eidi eidi@srbiau.ac.ir J Zarringhalam Background & aim: Morphine dependence is a compulsive pattern of drug taking, resulting from the positive reinforcement of the rewarding effects of drug taking and the negative reinforcement of withdrawal syndrome that accompanies the cessation of drug taking. The objective of this study was to investigate the effect of ethanol extract of aerial parts of the Mentha piperita in the acquisition, tolerance expression and dependence to morphine in adult male mice Methods: In the present study, 75 NMRI mice were divided into fifiteen groups. The Hot-plate test was used to survey the morphine activity. Morphine was injected (2.5, 5, 10, 20, 40 mg/kg, i.p.) twice daily for seven days, except in 8th day in which morphine was administrated at a single dose (50 mg/kg). The extract (50, 75, 100 mg/kg) was injected for eight days. The control animals were intact, and sham animals only received morphine. Naloxone was injected (10 mg/kg) five hours after the final dose of morphine and the withdrawal signs were recorded during a 30 minute period. The data were expressed as mean values ± SEM and tested, using analysis of one-way ANOVA test. Results: Peppermint extract at doses of 75 and 100 kg significantly improved the tolerance expression and dependence to morphine in animals and significantly reduced the symptoms of withdrawal. Conclusion: Peppermint extract was commuted morphine tolerance and dependence in mice.The plant contained component(s) that alleviate morphine withdrawal syndrome. The extract possibly be effective in improving tolerance to morphine. Morphine heroin losartan Homeostasis Regulation Opioid Angiotensin II 2015 4 01 53 65 http://armaghanj.yums.ac.ir/article-1-145-en.pdf
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Armaghane Danesh armaghanj 1728-6506 1728-6514 10.61186/armaghanj 2015 20 1 Determining the Effects of Morphine, Heroin, and Losartan and the Interaction of each on Losartan in Water Homeostasis Mechanisms by the Kidney in Adult Male Rabbits F Foroohi F_foroohi@ymail.com H Zamani R Pooyanfar Background & aim: Angiotensin II plays a key role in body fluid homeostasis. In the present study, the interaction of i.c.v. injection of morphine, heroin and losartan’s material, opioidergic and angiotensinergic systems on water intake in male rabbits were investigated. Methods: In the present experimental study, sixty-five male rabbits were divided into eight groups as follows: a control group without operation, control with surgical accompanying with cannula, the control surgery and cannulated with a saline injection, morphine (at doses of 5, 10 and 20 mg rabbit kg), heroin group (2.5, 5 and 10 mg/kg rabbit), losartan group (45, 90 and 180 mg kg rabbit), losartan (90 mg/kg rabbit) with morphine (5/10 kg rabbit), losartan (90 mg kg) and heroin (2.5 and 5 mg kg rabbits) were received. A cannula was used to ICV treatment in the right lateral ventricle of rabbits. After recovering the animals were deprived of water for 24 hours. The different drugs injected and the amount of drinking water was measured for one hour was measured. The gathered data were analyzed using one-way ANOVA and Tukey test. Result: The results showed that Morphine (agonist of opioid’s receptor, 10 µg/rabbit), Heroin (agonist of opioid’s receptor, 5 µg/rabbit), Losartan (antagonist of Angiotensin II receptor, 90 µg/rabbit) decreased water intake. Blockade of Angiotensin II with losartan, attenuate the inhibitory effect of Morphin and Heroin. Renin- Angiotensin System can regulate water intake via its effect on vasoconstriction and secretion of AVP and Aldestrone. All of these effects will be blocked with Angiotensin II antagonist (losartan). Conclusion: The Opioidergic system was influential in the adjustment of water and electrolyte balance through affecting peripheral and central receptors. The role of the Opioidergic system in regulation of drinking mechanisms was related to the secretion of Antiduretic hormone. According to the obtained results, a marked correlation was seen between angiogenesis systems, Opioidergic system and morphine (opioid) on water intake. Morphine heroin losartan Homeostasis Regulation Opioid Angiotensin II 2015 4 01 66 77 http://armaghanj.yums.ac.ir/article-1-146-en.pdf
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Armaghane Danesh armaghanj 1728-6506 1728-6514 10.61186/armaghanj 2015 20 1 Indicators of healthy reproduction program in Isfahan province in 2012 L Manzouri manzourileila@gmail.com SH Nematollahi P Aghdak P Arbab A Mansouri Background & aim: Healthy reproduction program help individuals maintain their health and improve family and community health by enabling them to make informed choices about their sexual and reproductive health. Therefore, this study was conducted to assess the healthy reproduction program in Isfahan province. Methods: It was a descriptive cross-sectional study. 9600 married women aged 15-49 years enrolled study according to multi stage clustered stratified random sampling. Data collection was done via developed standard questionnaire by experts of ministry of health and medical education. Samples were been questioned by 177 trained health providers in their home. Data analysis was performed by SPSS 16 software using descriptive statistic. Results: Total coverage of contraceptive method use (modern and traditional) was 89.5% and modern contraceptive method coverage was 67.8%. The most and the least common used methods of contraception were condom (22%) and a-month contraceptive injection (0.6%).The most common cause of non-use contraceptive method was suspicious to pregnancy and pregnancy. The percentage of changing method over a year ago was 23.Unintended pregnancy and unmet need were 18% and 6.5%, respectively. Correct consumption of oral contraceptive pills and awareness of emergency contraception method were 57% and 52%, respectively.73.5% of women aged 15-49 years used governmental health care services and satisfaction rate was more than 90%. Conclusion: To decrease unwanted pregnancy and increase women’s knowledge about correct use of oral contraceptive and emergency contraceptive method, health care provider should pay special attention to contraceptive counseling to clients. Indicators healthy reproduction program Iran 2015 4 01 78 88 http://armaghanj.yums.ac.ir/article-1-142-en.pdf