Yasuj University Of Medical Sciences
Armaghane Danesh
1728-6506
1728-6514
19
11
2015
2
1
Risk Factors for Non-:union: Fractures of the Clavicle Mid-shift Following the Use of Non-surgical Treatment on Patients Admitted to Poursina Hospital, 2010 - 2012
921
930
FA
kamran
Asadi
Orthopedic Research Center, Poursina Hospital, Guilan University of Medical Sciences, Rasht, Iran,
N
Ahmadreza
Mirbolouk
Orthopedic Research Center, Poursina Hospital, Guilan University of Medical Sciences, Rasht, Iran,
@yahoo.com
Y
Ali
Karimi
Orthopedic Research Center, Poursina Hospital, Guilan University of Medical Sciences, Rasht, Iran,
N
Mohsen
Mardani
1Orthopedic Research Center, Poursina Hospital, Guilan University of Medical Sciences, Rasht, Iran,
N
Peyman
Asadi
Departmenr of of Emergency Medicine, Guilan University of Medical Sciences, Rasht , Iran.
N
Sedigheh
Samimian
Orthopedic Research Center, Poursina Hospital, Guilan University of Medical Sciences, Rasht, Iran,
N
Background & aim: Lack of attention to patient characteristics and type of fracture in the middle third clavicle fractures will lead to a non-:::union::: complication. Identification of risk factors in non-:::union::: is very important to choose the accurate treatment. The purpose of this study was to investigate the risk factors of non-:::union::: following the non-surgical treatment.
Methods: This descriptive study was performed on 308 patients older than 18 years of age with fracture of the middle third of the clavicle with displacement. Patient demographic data and information related to fracture (commination, side of fracture, displacement and angulation) were recorded.Patients at two and six weeks, three months and six months after fracture were followed. Data were analyzed using SPSS version 16 software, chi-square tests, Mann-Whitney and logistic regression.
Results: Among the factors associated with :::union:::, the displacement (P = 0.04), commination (P = 0.006) and educational level (P = 0.002) are predictive factors were considered non-:::union:::.
Conclusions: Recognition and predicting the risk factors of non-:::union::: in patients with fractures of the middle third of the clavicle could be a clinical guideline for the selection of surgical or non-surgical treatment.
عclavicle fracture, non-:union:, non-surgical treatment
http://armaghanj.yums.ac.ir/article-1-82-en.html
http://armaghanj.yums.ac.ir/article-1-82-en.pdf
Yasuj University Of Medical Sciences
Armaghane Danesh
1728-6506
1728-6514
19
11
2015
2
1
The Effect of Pomegranate Seed Oil on the Proliferation of Human Breast Cancer Cell Lines MCF-7 and MDA-MB468
930
937
FA
Mahsa
Servatkhah
Cellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran
N
reza
mahmoudi
Cellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran
N
alimohamad
kamali
Cellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran
N
maryam
tajale
Cellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran
N
mehrzad
jafari barmak
Cellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran
N
mohsen
nikseresht
Cellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran
nikmohsen@yahoo.com
Y
Background and aim: Breast cancer is the most common cancer which is threatening the health of women worldwide. Recent studies have found that pomegranate seed oil extract, may have potential anti cancer effect(s). The purpose of this study was to investigate the effects of pomegranate seed oil on the proliferation of human breast cancer cell lines MCF-7 and MDA-MB468.
Methods: MCF-7 and MDA-MB468 cell lines were provided and grown in the culture media of RPMI-1640 containing 10% fetal bovine serum with the proper antibiotic. The pomegranate seed oil was extracted using petroleum ether. Cells were treated with different concentrations of pomegranate seed oil (100-1500 µg/ml) and viability was evaluated by using MTT assay. All of the experiments were performed triplicate.
Result: After a period of 24, 48, and 72 hrs, the IC50 in MCF-7 cell lines and MDA-MB468 cell lines were 1150,742,731µg/ml and 842,700,588 µg/ml, respectively.
Conclusions: The results revealed that pomegranate seed oil has the cytotoxicity effect on the two mentioned cell lines. Moreover, at different times with different concentrations, it (time and concentration dependent) prevented the proliferation of breast cancer cells. Therefore, perhaps it takes as a nutritional factor in the prevention of breast cancer.
MCF-7 cell line, MDA-MB468 cell line, pomegranate seed oil, MTT assay
http://armaghanj.yums.ac.ir/article-1-83-en.html
http://armaghanj.yums.ac.ir/article-1-83-en.pdf
Yasuj University Of Medical Sciences
Armaghane Danesh
1728-6506
1728-6514
19
11
2015
2
1
Long-term Effects of Dexamethasone on Reproductive Parameters in Male Mice
938
947
FA
jalogoden
Gouyandeh
Young Researchers and Elite Club, Najafabad Branch, Islamic Azad University, Najafabad, Iran
N
merdad
modaaresi
Mehrdad Modaresi , Department of Physiology, Khorasgan (Isfahan) Branch, Islamic Azad University, Isfahan, Iran
mehrdad_modaresi@hotmail.com
Y
Background & aim: The adverse effect of chemical drugs such as dexamethasone as anti-inflammatory -steroidal drugs on different body systems and infertility and reproductive efficiency is of concern. The purpose of this study was to evaluate the long-term effects of dexamethasone on the reproductive system in male rats.
Methods: In the present experimental study, fifty matured male mice were divided into five groups including control, placebo and three treatment groups. Control group had no injections, placebo group only received normal saline and treatments groups received dexamethasone (0.1, 0.5 and 1 mg/kg) which was injected in peritoneum every other day for a period of twenty days. Their Testosterone was measured by ELISA and testes were dissected for histological examination. The data were analyzed using SPSS 11.5 software.
Results: Significant increases were shown in FSH level in all three groups treated with dexamethasone. LH in treatment group of 0.1 mg/kg decreased, but at dose of 1 mg/kg increased significantly.Testosterone levels in a dose of 1 mg/kg significantly increased compared with the control group (p<0.05). However, testis weight, the rate of testicular germ cells, primary spermatocytes, epididymal sperm and fertility significantly increased in all three groups (p<0.05).
Conclusion: Dexamethasone had a negative effect on reproduction therefore, the use of this medication at different doses and time periods considers the possible complications beforehand.
Keywords: .
Dexamethasone, Reproduction, Testosterone, Male Mice
http://armaghanj.yums.ac.ir/article-1-84-en.html
http://armaghanj.yums.ac.ir/article-1-84-en.pdf
Yasuj University Of Medical Sciences
Armaghane Danesh
1728-6506
1728-6514
19
11
2015
2
1
Determination of Serum level of Triose Phosphate Isomerase in lung Cancer Patients
948
954
FA
mohamadali
Ghayyoumi
1Department of Internal Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
N
mahsa
Mansouri
2Cancer Proteomics and Biomarkers Lab, Institute for Cancer Research, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
mahsa.mansouri@gmail.com
Y
Background & aim: Due to the fact that lung cancer is the most common cause of cancer-related deaths worldwide, identification of biomarkers is of great importance for early detection. One of molecules which may be used as a diagnostic biomarker is Threose Phosphate Isomerase (TPI). The purpose of this study was to evaluate serum levels of Threose phosphate isomerase in patients with lung cancer.
Methods: In this case-control study, 50 males with a mean age of 65.1±11.4 were included. Twenty-seven patients had squamous cell carcinoma, seven had small cell carcinoma and 16 had adenocarcinoma respectively. Meanwhile, 38 healthy men (mean age 65.1±11.4) were selected as the control group. ELISA technique was used to measure the TPI. Collected data were analyzed using ANOVA and t-test.
Results: TPI serum levels of patients were not statistically significant compared with the control group (p =0.76). Moreover, a separate analysis of sub groups of lung cancer demonstrated that serum levels of TPI in the sub group of lung cancer group compared with the control group had no significant difference.
Conclusions: No correlation between serum levels of TPI and lung cancer was observed. It probably indicated the TPI role in different types of cancer and its geographical distribution in human populations.
Lung cancer, ELISA, TPI
http://armaghanj.yums.ac.ir/article-1-85-en.html
http://armaghanj.yums.ac.ir/article-1-85-en.pdf
Yasuj University Of Medical Sciences
Armaghane Danesh
1728-6506
1728-6514
19
11
2015
2
1
The Effects of Hydro-alcoholic Extract of Raspberry Fruit on Ovarian follicles and serum parameters in Poly Cystic Ovary Syndrome-Induced Rat
955
968
FA
mohamad
Nabiuni
Department of Cell and Molecular Biology, Kharazmi University, Tehran, Iran
harazmi@gmail.com
Y
seyedeh rezvan
*, Panahandeh
Department of Animal Biology, Faculty of Biological Sciences, Kharazmi University, Tehran, Iran,
N
solmaz
, Doostikhah
Department of Animal Biology, Faculty of Biological Sciences, Kharazmi University, Tehran, Iran,
N
latefeh
Karimzadeh Bardei
Animal Center & Cellular And Molecular Research Laboratory, Kharazmi University, Tehran, Iran.
N
Background & aim: Polycystic Ovary Syndrome is an endocrine disorder leading to lack of ovulation and has inflammatory aspects. Raspberry extract, with possession of bioactive compounds such as Anthocyanins and polyphenols, have anti-inflammatory properties. In this study, the anti-inflammatory effects of raspberry extract on the development process of ovarian follicles and hormones level of pituitary, ovarian, and liver in rats suffering from PCOS were examined.
Methods: In the present experimental study, 120 adult Wistar rats were divided into three groups of control, PCOS, and treated with raspberry. The induction of syndrome was done by 2mg Estradiol valerate. After a period of 60 days, 100, 150 and 200 mg/kg BW raspberry extract was injected intraperitoneally. Control group received no injection. Ten days after the last injection, all groups were anesthetized by chloroform and the serum and ovary of all groups were collected in order to investigate the histological and serologic changes. Data obtained were analyzed by using one-way ANOVA.
Results: Raspberry-treated group showed a significant decrease in the hormones rate of testosterone, estradiol, LH, and CRP compared with PCOS (p<0.05), whereas a significant increase was observed in the serum level of Progesterone and FSH (p<0.05). A significant increase was observed in the number of corpus luteum and granulosa layer thickness in the raspberry-treated group compared with PCOS (p<0.05).
Conclusion: The results demonstrated that the antioxidant and anti-inflammatory effects of raspberry extract was effective on regulating the hormones, CRPand improving of cysts which led to the initiation of ovulation.
Poly Cystic Ovary Syndrome, Raspberry, Estradiol valerate, Corpus luteums
http://armaghanj.yums.ac.ir/article-1-86-en.html
http://armaghanj.yums.ac.ir/article-1-86-en.pdf
Yasuj University Of Medical Sciences
Armaghane Danesh
1728-6506
1728-6514
19
11
2015
2
1
Estimation of the workload added on the health system due to unwanted pregnancies and Children born of these pregnancies in kohgiloyeh Boyrahmad province 2010-2011
969
980
FA
zebaneh
Tabeshfar
Social Determinants of Health Research Center, Yasuj University Of Medical Sciences. Yasuj, Iran
z.tabeshfar@yahoo.com
Y
reza
chaman
Social Determinants of Health Research Center, Yasuj University Of Medical Sciences. Yasuj, Iran
N
hamidreza
Ghaffarian Shirazi
Social Determinants of Health Research Center, Yasuj University Of Medical Sciences. Yasuj, Iran
N
abdolmohamad
Saddat
Social Determinants of Health Research Center, Yasuj University Of Medical Sciences. Yasuj, Iran
N
Background & aim: Unwanted pregnancy increases maternal and child mortality and increases health centers workload. The purpose of this study was to estimate the additional workload caused by unwanted pregnancies in the province's health system of Kohgilouyeh & Boyerahmad province, Iran.
Methods: The present cross-sectional study was conducted in the second half of 2009 on the prenatal care for pregnant women referred to city health centers. Frequency of maternal and child care were assessed according to the latest Ministry of Health guidelines. Average time required to provide each patient was calculated based on the role results, then added workload was assessed. Data were analyzed using SPSS software.
Results: An overall 350 unwanted pregnancy cases were identified. Assuming the same unwanted pregnancies in the first half and the second year of 2009 total of 21,140 times the equivalent of 3696 hours of extra work visit were added to the labor working primary health care centers in the city.
Conclusion: Unwanted pregnancies resulting in increased staff workload of health centers, and if not provided with sufficient manpower, it may lead to the reduction of maternal and child health care qualities of these centers.
Unwanted pregnancy, Health systems, Health center, Workload, refer time
http://armaghanj.yums.ac.ir/article-1-87-en.html
http://armaghanj.yums.ac.ir/article-1-87-en.pdf
Yasuj University Of Medical Sciences
Armaghane Danesh
1728-6506
1728-6514
19
11
2015
2
1
Health-related Quality of Life in Two Factories in Yasuj City
981
993
FA
hamidreza
Mokarami
Department of Ergonomics, Shiraz University of Medical Sciences, Shiraz, Iran
Y
ebrahim
Taban
Department of Occupational Health Engineering, Tarbiat Modares University, Tehran, Iran
N
mohsen
, Yazdani Aval
Department of Occupational Health Engineering, Tarbiat Modares University, Tehran, Iran
N
mohamad
Taghavi
Kohgilouyeh & Boyer -Ahmad Health Care Management of Social Security Organization, Yasuj, Iran
N
hossen
Marioryad
Social Determinants of Health Research Center, Yasuj University of Medical Sciences, Yasuj, Iran
N
Background & aim: Work is an important component of QOL therefore work-related factors could be a significant predictor in this respect.The current study was aimed to asses QOL and its association with socio-demographic, health and work-related factors in two factories in Yasuj, Iran.
Methods: In the present cross-sectional study, participants were 280 workers of two factories. The Persian version of World Health Organization Quality of Life-Brief (WHOQOL-BREF) was used to assess the QOL. A questionnaire was developed to assess the socio-demographic, health and work-related factors. Data were analyzed using descriptive statistics.
Results: The present study revealed that the means (SD) of physical health, psychological health, social relationships, and environment domains of QOL were 13.2 (2.7), 13.3 (2.6), 14.2 (3.5) and 12.6 (2.5), respectively. A multiple linear regression demonstrated that the types of job, exercise activity, working schedule, sleep quality, smoking, and conflict between work and social life were associated with physical health domain whereas, working schedule, marital status, working demand, sleep quality, BMI, and conflict between work and individual life were significantly associated with psychological health domain. Working schedule, working demand, sleep quality, conflict between work and individual life were significantly associated with social relationship domain however, working demand, working schedule, smoking, sleep quality, working hour, job satisfaction, marital status and exercise activity were significantly associated with environment domain.
Conclusion: To improve workers' QOL, the intervention programs should focus on improving work environment, working schedule, occupational training and restricting working hours.
Quality of Life (QOL), Industries, Workers, Yasuj
http://armaghanj.yums.ac.ir/article-1-88-en.html
http://armaghanj.yums.ac.ir/article-1-88-en.pdf
Yasuj University Of Medical Sciences
Armaghane Danesh
1728-6506
1728-6514
19
11
2015
2
1
The impact of Sexual Cognitive Reconstruction on reducing Sexual Problems and increasing sexual satisfaction of couples (elementary students Parents)
994
1007
FA
mahshid
Sasanpour
Department of Department, Yerevan State University, Irawan, Armenia
:m_sasan49@yahoo.com
Y
gayana
Shahverdyan
Department of Department, Yerevan State University, Irawan, Armenia
N
ahmad
Ahmadi
Department of Counseling, University of Isfahan, Isfahan, Iran
N
Background & aim: Inadequate or incorrect information, thoughts and maladaptive beliefs about sex and anxiety is a common cause of sexual problems. These problems can be treated properly by proper training so that the couples could reach desirable marital relationship.The purpose of this study was to determine the effect of sexual cognitive restructuring education on reducing sexual problems and sexual satisfaction of couples in Isfahan, Iran.
Methods: In the present experimental study, the pretest-posttest with control group, 120 parents of elementary school students in Isfahan were chosen and were randomly divided into experimental and control groups. The research instruments were Hooper sexual problems and Larson sexual satisfaction questionnaires, and ten sessions, two hours each, were held in order to educate sexual cognitive restructuring for the experimental group, but no intervention for control group was held. Data were analyzed using covariance test.
Results: sexual training cognitive restructuring reduced the total number of sexual problems and all its aspects and also was effective in increasing sexual satisfaction of couples (P <0.05).
Conclusion: Due to the reason that many psychological distress and marital conflicts are caused by lack of sexual satisfaction, therefore, proper training and cognitive changes in people may help to strengthen the foundation of the family.
Cognitive restructuring, couples, sexual problems, sexual satisfaction, sexual training
http://armaghanj.yums.ac.ir/article-1-89-en.html
http://armaghanj.yums.ac.ir/article-1-89-en.pdf
Yasuj University Of Medical Sciences
Armaghane Danesh
1728-6506
1728-6514
19
11
2015
2
1
Hand Fatigue Analysis Using Quantitative Evaluation of Variability in Drawing Patterns
1008
1020
FA
mohamadali
Sanjari
Department of Basic Sciences, Iran University of Medical Science, Tehran, Iran
N
farzaneh
, Haghighat
2Department of physiotherapy, Iran University of Medical Science, Tehran, Iran
haghighat_fa@yahoo.com
Y
gholamreza
Olyaee
Department of physiotherapy, Tehran University of Medical Science, Tehran, Iran
N
aliashraf
Jamshidi
1Department of Basic Sciences, Iran University of Medical Science, Tehran, Iran
N
Background & aim: Muscle fatigue is defined as the reduced power generation capacity of a muscle or muscle group after activity which can lead to a variety of lesions. The purpose of the present study was to define the fatigue analysis by quantitative analysis using drawing patterns.
Methods: the present cross-sectional study was conducted on 37 healthy volunteers (6 men and 31 women) aged 18-30 years. Before & immediately after a fatigue protocol, quantitative assessment of hand drawing skills was performed by drawing repeated, overlapping, and concentric circles. The test was conducted in three sessions with an interval of 48-72 hours. Drawing was recorded by a digital tablet. Data were statistically analyzed using paired t-test and repeated measure ANOVA.
Result: In drawing time series data analysis, at fatigue level of 100%, the variables standard deviation along x axis (SDx), standard deviation of velocity on both x and y axis (SDVx and SDVy) and resultant vector velocity standard deviation (SDVR), showed significant differences after fatigue (P<0.05). In comparison of variables after the three fatigue levels, SDx showed significant difference (P<0.05).
Conclusions: structurally full fatigue showed significant differences with other levels of fatigue, so it contributed to significant variability in drawing parameters. The method used in the present study recognized the fatigue in high frequency motion as well.
Fatigue, Variability, Drawing pattern
http://armaghanj.yums.ac.ir/article-1-90-en.html
http://armaghanj.yums.ac.ir/article-1-90-en.pdf