fa تأثیر برنامه توانبخشی هوازی و مصرف کورکومین بر حداکثراکسیژن مصرفی و برخی عوامل خطرزای قلبی ـ عروقی(هموسیستئین و پروتتئین واکنش دهنده سی) در بیماران سندروم گلیسمی ویژه فیزیولوژی ورزش Sport Physiology پژوهشي Research <span style="font-size:12pt"><span style="background:white"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">زمینه و هدف:</span></span></span></b> <span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">توانبخشی هوازی و مصرف کورکومین به عنوان دو روش غیردارویی مورد توجه قرار گرفته‌اند که می‌توانند تأثیرات مثبتی بر سلامتی قلبی ـ عروقی داشته باشند</span></span></span><span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">، لذا هدف از این مطالعه تعیین و </span></span></span><span lang="AR-SA" style="font-size:8.0pt"><span style="font-family:Yagut">تأثیر برنامه توانبخشی هوازی و مصرف کورکومین بر <span style="color:black">حداکثراکسیژن مصرفی</span></span></span> <span lang="FA" style="font-size:8.0pt"><span style="font-family:Yagut">و برخی</span></span> <span lang="AR-SA" style="font-size:8.0pt"><span style="font-family:Yagut">عوامل خطرزای قلبی ـ عروقی(هموسیستئین و پروتتئین واکنش دهنده سی) در بیماران سندروم گلیسمی ویژه بود.</span></span></span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="background:white"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span lang="AR-SA" style="font-size:8.0pt"><span style="font-family:Yagut"></span></span></span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="background:white"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="tab-stops:80.25pt"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="AR-SA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">روش بررسی:</span></span></span></b><span lang="AR-SA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black"> در این مطالعه نیمه‌تجربی که در سال 1403 انجام شد، جامعه آماری تحقیق را کلیه مردان دارای بیماری </span></span></span><span dir="LTR" style="font-size:8.0pt"><span arial="" style="font-family:"><span style="color:black">GABS</span></span></span><span style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black"> شهر شیراز تشکیل دادند.</span></span></span> <span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">تعداد 40 مرد مبتلا به </span></span></span><span dir="LTR" style="font-size:8.0pt"><span arial="" style="font-family:"><span style="color:black">GABS</span></span></span> <span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">با میانگین سنی</span></span></span><span lang="AR-SA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">4/4</span></span></span><span lang="AR-SA" style="font-size:10.0pt"><span calibri="" style="font-family:"><span style="color:black">&plusmn;</span></span></span><span lang="AR-SA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">5/35</span></span></span><span lang="AR-SA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black"> سال</span></span></span> <span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">انتخاب و به طور تصادفی به چهار گروه؛ تمرین هوازی(10 نفر)، تمرین هوازی+ کورکومین(10 نفر)، کورکومین(10 نفر) و کنترل(10 نفر) تقسیم شدند. گروه‌های تجربی (گروه تمرین هوازی و گروه تمرین هوازی+ کورکومین) به مدت هشت هفته یک برنامه تمرینی توانبخشی هوازی زیر بیشینه شامل انجام دادند، تمرین به کار گرفته شامل </span></span></span><span lang="AR-SA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">سه جلسه در هفته تمرینات توانبخشی و هر جلسه فعالیت شامل سه بخش؛ گرم کردن، فعالیت اصلی و سرد کردن بود.</span></span></span> <span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">گروه مکمل مقدار یک گرم کورکومین دریافت کرد، در حالی که گروه کنترل همین مقدار دارونما به مدت هشت هفته دریافت کردند</span></span></span><span dir="LTR" style="font-size:8.0pt"><span arial="" style="font-family:"><span style="color:black">.</span></span></span><span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black"> داده‌های </span></span></span><span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">جمع‌آوری شده با استفاده از آزمون‌های آماری مقایسه</span></span></span> <span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">بین</span></span></span> <span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">گروهی</span></span></span> <span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">با</span></span></span> <span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">استفاده</span></span></span> <span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">از</span></span></span> <span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">تحلیل</span></span></span> <span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">واریانس</span></span></span> <span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">ترکیبی</span></span></span> <span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">و</span></span></span> <span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">پس</span></span></span> <span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">از</span></span></span> <span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">آن</span></span></span> <span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">آزمون</span></span></span> <span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">تعقیبی</span></span></span> <span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">توکی</span></span></span> <span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">تجزیه و تحلیل شدند.</span></span></span> <span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">سطح</span></span></span> <span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">معناداری</span></span></span> <span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">کمتر</span></span></span> <span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">از</span></span></span><span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black"> 05/0 </span></span></span><span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">در</span></span></span> <span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">نظر</span></span></span> <span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">گرفته</span></span></span> <span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">شد</span></span></span><span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">.</span></span></span><span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black"></span></span></span></span></span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="background:white"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="tab-stops:80.25pt"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times="">&nbsp;</span></span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="background:white"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="tab-stops:80.25pt"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">یافته ها:</span></span></span></b> <span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">&nbsp;نتایج نشان می</span></span></span><span dir="LTR" style="font-size:8.0pt"><span calibri="" style="font-family:"><span style="color:black">‌</span></span></span><span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">دهد مقادیر </span></span></span><span dir="LTR" style="font-size:8.0pt"><span arial="" style="font-family:"><span style="color:black">VO₂max</span></span></span> <span style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">&nbsp;بین گروه‌های تمرین هوازی + کورکومین</span></span></span> <span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">با گروه‌های کورکومین و دارونما و بین گروه کورکومین با دارونما تفاوت معنی‌داری داشتند. هم‌چنین مقادیر</span></span></span><span dir="LTR" style="font-size:8.0pt"><span arial="" style="font-family:"><span style="color:black">Hcy</span></span></span> <span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">سرمی بین گروه تمرین هوازی و دارونما و بین گروه تمرین هوازی+ کورکومین و دارونما تفاوت معنی‌داری داشتند. به علاوه نتایج نشان می دهد مقادیر </span></span></span><span dir="LTR" style="font-size:8.0pt"><span arial="" style="font-family:"><span style="color:black">CRP</span></span></span><span style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black"> سرمی بین گروه تمرین هوازی و دارونما و بین گروه تمرین هوازی + کورکومین و دارونما تفاوت معنی‌داری داشتند.</span></span></span></span></span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="background:white"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="tab-stops:80.25pt"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b>&nbsp;&nbsp;</b><b><span lang="AR-SA" style="font-size:6.0pt"><span style="font-family:Yagut"><span style="color:black"></span></span></span></b></span></span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="background:white"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="tab-stops:80.25pt"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="AR-SA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">نتیجه‌گیری: </span></span></span></b><span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">بنابراین می‌توان نتیجه گرفت استفاده از تمرینات توانبخشی به همراه مصرف کورکومین برای افزایش توان هوازی و کاهش عوامل خطر قلبی، برای بیماران </span></span></span><span dir="LTR" style="font-size:8.0pt"><span arial="" style="font-family:"><span style="color:black">GABS</span></span></span><span style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black"> توصیه می‌شود.</span></span></span></span></span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="background:white"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="tab-stops:80.25pt"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:2.0pt"><span style="font-family:Yagut"><span style="color:black"></span></span></span></span></span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="background:white"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="AR-SA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">&nbsp;</span></span></span></b><span lang="AR-SA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">توانبخشی هوازی، کورکومین، </span></span></span><span dir="LTR" style="font-size:8.0pt"><span arial="" style="font-family:"><span style="color:black">Hcy</span></span></span><span lang="AR-SA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">، </span></span></span><span dir="LTR" style="font-size:8.0pt"><span arial="" style="font-family:"><span style="color:black">CRP</span></span></span><span style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black"> ، </span></span></span><span dir="LTR" style="font-size:8.0pt"><span arial="" style="font-family:"><span style="color:black">VO₂max</span></span></span> <span lang="FA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">، </span></span></span><span lang="AR-SA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black">بیماران </span></span></span><span dir="LTR" style="font-size:8.0pt"><span arial="" style="font-family:"><span style="color:black">GABS</span></span></span><span lang="AR-SA" style="font-size:10.0pt"><span style="font-family:Yagut"><span style="color:black"></span></span></span></span></span></span></span></span></span></span> <span style="font-size:12pt"><span new="" roman="" style="font-family:" times=""><b><span style="font-family:" utsaah="">Abstract</span></b><br> <span style="font-family:" utsaah=""><b>Objective:</b> The aim of the present study was to investigate the effect of an aerobic rehabilitation program and curcumin consumption on </span><span style="font-size:10.0pt"><span style="color:black">VO</span></span>_{<span style="font-size:10.0pt"><span style="color:black">2</span></span>}<span style="font-size:10.0pt"><span style="color:black">max</span></span><span style="font-family:" utsaah=""> and cardiovascular risk factors (Hcy and PRC) in patients with GABS.</span> <b><span style="font-family:" utsaah="">Methods:</span></b><span style="font-family:" utsaah=""> The research was conducted experimentally under laboratory conditions and was applied in nature, utilizing a cross-sectional research design. The research plan included random allocation to four groups: aerobic exercise, aerobic exercise + curcumin, curcumin, and control group. The aerobic exercise group and the aerobic exercise + curcumin group participated in a structured exercise program focused on rehabilitation exercises, while the curcumin group received the supplement, and the control group received no intervention.</span> <b><span style="font-family:" utsaah="">Results:</span></b><span style="font-family:" utsaah=""> The results indicated that the </span><span style="font-size:10.0pt"><span style="color:black">VO</span></span>_{<span style="font-size:10.0pt"><span style="color:black">2</span></span>}<span style="font-size:10.0pt"><span style="color:black">max</span></span><span style="font-family:" utsaah=""> values were significantly different between the aerobic exercise + curcumin group and both the curcumin and placebo groups, as well as between the curcumin group and the placebo group. Additionally, serum Hcy levels were significantly different between the aerobic exercise and placebo groups and between the aerobic exercise + curcumin and placebo groups. Furthermore, the serum PRC levels were significantly different between the aerobic exercise and placebo groups and between the aerobic exercise + curcumin and placebo groups.</span> <b><span style="font-family:" utsaah="">Conclusion:</span></b><span style="font-family:" utsaah=""> Therefore, it can be concluded that the use of rehabilitation exercises along with curcumin consumption is recommended for improving aerobic capacity and reducing cardiovascular risk factors in patients with GABS.</span><span lang="AR-SA" dir="RTL" style="font-family:"B Yagut""></span></span></span><br> &nbsp; توانبخشی هوازی, کورکومین Aerobic rehabilitation, curcumin, Hcy, PRC, VO2max, GABS patients. 65 79 http://armaghanj.yums.ac.ir/browse.php?a_code=A-10-1164-7&slc_lang=fa&sid=1 H Ghaedi هادی قائدی ghaedi.hadi@gmail.com 100319475328460032169 100319475328460032169 No Department of Exercise Physiology, Lamerd Branch, Islamic Azad University, Lamerd, Iran گروه فیزیولوژی ورزشی، واحد لامرد، دانشگاه آزاد اسلامی، لامرد، ایران M Ghahramani مهران قهرمانی mehran.physiology@gmail.com 100319475328460032170 100319475328460032170 Yes Department of Exercise Physiology, Ker.C., Islamic Azad University, Kermanshah, Iran گروه فیزیولوژی ورزشی، واحد کرمانشاه، دانشگاه آزاد اسلامی، کرمانشاه، ایران، S Behzadi سمیه بهزادی 100319475328460032171 100319475328460032171 No Department of Exercise Physiology, Lamerd Branch, Islamic Azad University, Lamerd, Iran گروه فیزیولوژی ورزشی، واحد لامرد، دانشگاه آزاد اسلامی، لامرد، ایران M Ghahramani محمد قهرمانی ghahramani2007@gmail.com 100319475328460032172 100319475328460032172 No Department of Physical Education, Technical and Vocational University (TVU), Tehran, Iran گروه تربیت بدنی ، دانشگاه ملی مهارت، تهران، ایران