Armaghane Danesh
ارمغان دانش
armaghanj
Medical Sciences
http://armaghanj.yums.ac.ir
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admin
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ارزیابی تأثیر ضد باکتریایی عصارههای دارچین، زنجبیل، چای ترش، زرشک و پونه کوهی بر تعدادی از باکتریهای استاندارد گرم مثبت و گرم منفی
Evaluation of Antibacterial Effect of Cinnamomum verum, Zingiber officinale, Hibiscus sabdariffa, Berberis vulgaris and Mentha Pulegium plant Extracts on some of Gram- Positive and Gram-Negative Bacteria
میکروبیولوژی
Microbiology
پژوهشي
Research
<strong><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">زمینه و هدف</span></span></span></strong><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">: مصرف</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">روز</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">افزون</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">آنتیبیوتیکها</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">علیه</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">عفونت</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">ناشی</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">از</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">میکروارگانیسمها سبب</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">افزایش</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">مقاومت</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">دارویی</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">شده</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">است.</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">ا</span></span></span><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">ین</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">امر</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">سبب</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">شده</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">تا</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">پژوهشهای</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">وسیعی</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">بر</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">روی</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">ترکیبات</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">گیاهی</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">با</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">خاصیت</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">ضدمیکروبی</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">و</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">اثربخشی</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">بیشتر</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">به عنوان</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">جایگزین</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">آنتیبیوتیکی</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">صورت</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">گیرد.</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">هدف</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">از این</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">تحقیق تعیین و</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">ارزیابی</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">فعالیت</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">ضدباکتریایی عصارههای دارچین</span></span></span><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">،</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">زنجبیل، چای ترش، زرشک و پونه کوهی بر تعدادی از </span></span></span><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">باکتریهای استاندارد </span></span></span><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">ا</span></span></span><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">ستافیلوکوکوس ساپروفیتیکوس، استافیلوکوکوس اور ئوس، </span></span></span><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">انتروکوکوس</span></span></span><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;"> فکالیس، سودومونا آئروژینوزا، اسینتوباکتربومانی، کلبسیلا پنومونیه واشریشیاکولی بود.</span></span></span><br>
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<strong><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">روش بررسی: </span></span></span></strong><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">این یک مطالعه تجربی میباشد که در سال 1389 در دانشگاه </span></span></span><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">علوم پزشکی کردستان انجام شد</span></span></span><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">. عصاره</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">الکلی</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">گیاهان دارچین، زنجبیل، چای ترش، زرشک وپونه کوهی با روش ماسراسیون</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">تهیه</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">شد</span></span></span><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">. عملکرد</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">ضد</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">باکتریایی عصارهها بر</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">روی</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">چندین</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">رده</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">استاندارد</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">باکتریایی</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">با</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">روش</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">چاهکگذاری پس از</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">سه</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">بار</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">تکرار انجام و</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">میانگین</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">قطر</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">هاله</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">عدم</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">رشد</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">اندازهگیری</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">و</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">ثبت شد. سپس</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">حداقل</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">غلظت</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">مهاری</span></span></span><span dir="LTR"><span style="font-size: 8pt;"><span style="font-family: Arial,sans-serif;"><span style="color: black;">MIC)</span></span></span></span><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">)</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">با روش</span></span></span><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">رقیق سازی با میکروپلیت</span></span></span><span style="font-size: 8pt;"><span style="font-family: Arial,sans-serif;"><span style="color: black;">(</span></span></span><span dir="LTR"><span style="font-size: 8pt;"><span style="font-family: Arial,sans-serif;"><span style="color: black;">(Broth Microdilution</span></span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">تعیین شد. میانگین</span></span></span><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;"> قطر</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">هاله</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">عدم رشد</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">با</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">استفاده</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">از</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">آزمون آماری مقایسه میانگینها به روش دانکن تجزیه و تحلیل شد.</span></span></span><br>
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<br>
<strong><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">یافتهها </span></span></span></strong><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">:</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">در</span></span></span><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;"> این</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">تحقیق</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">بیشترین</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">اثر</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">ضدباکتریایی</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">مربوط به</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">عصاره زرشک و زنجبیل بر روی</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">استافیلوکوک</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">ساپروفیتیکوس به ترتیب</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">با قطرهاله عدم رشد 25 و23 میلیمتر بوده است(05/0></span></span></span><span dir="LTR"><span style="font-size: 8pt;"><span style="font-family: Arial,sans-serif;"><span style="color: black;">p</span></span></span></span><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">)</span></span></span><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">. عصاره چای ترش بر روی استافیلوکوک ساپروفیتیکوس و عصاره پونه کوهی برروی اشیریشیا کولی و استافیلو کوک ساپروفیتیکوس دارای بیشترین اثر ضدباکتریایی به ترتیب با قطر هاله عدم رشد 16، 13و 13 میلیمتر بودهاند(05/0></span></span></span><span dir="LTR"><span style="font-size: 8pt;"><span style="font-family: Arial,sans-serif;"><span style="color: black;">p</span></span></span></span><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">)</span></span></span><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">. بیشترین اثر ضدباکتریایی دارچین بر استافیلوکوک اورئوس با قطر هاله عدم رشد 19 میلیمتر بوده است. حداقل</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">غلظت</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">بازدارندگی</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">از</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">رشد مربوط به</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">عصاره</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">گیاهان</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">زرشک </span></span></span><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">و زنجبیل </span></span></span><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">علیه</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">استافیلوکوکوس ساپروفیتیکوس با 1/3 میلیگرم بر میلیلیتر و</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">پایینتر</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">از</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">سایر</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">انواع</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">عصارهها</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">مشاهده شد. باکتری</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">سودوموناس</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">ائروژینوزا نسبت به اکثر</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">عصاره</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">گیاهان</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">مورد</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">بررسی</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">مقاومت</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">نشان</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">داد(05/0></span></span></span><span dir="LTR"><span style="font-size: 8pt;"><span style="font-family: Arial,sans-serif;"><span style="color: black;">p</span></span></span></span><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">)</span></span></span><span dir="LTR"><span style="font-size: 8pt;"><span style="font-family: Arial,sans-serif;"><span style="color: black;">.</span></span></span></span><br>
<br>
<span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;"> <strong>نتیجه</strong></span></span></span> <strong><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;"></span></span></span></strong><strong><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">گ</span></span></span></strong><strong><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">یری</span></span></span></strong><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;"> : نتایج این بررسی نشان داد عصارههای این مطالعه </span></span></span><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">به و</span></span></span><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">یژه عصاره زرشک </span></span></span><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">خاصیت ضدباکتریایی مؤثری بر روی اکثر سویههای مورد بررسی دارد و برای</span></span></span><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;"> ن</span></span></span><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">شان دادن</span></span></span><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;"> اثر</span></span></span><span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">ات</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">بهینه</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">ضدباکتریال</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">عصارههای</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">مورد</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">مطالعه،</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">بررسی</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">بر روی حیوانات آزمایشگاهی</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">و</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">تعیین</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">اثرات</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">بالینی</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">آنها</span></span></span> <span style="font-size: 10pt;"><span style="font-family: Yagut;"><span style="color: black;">پیشنهاد میشود.</span></span></span><br>
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<strong>Background & aim:</strong>Increasing use of antibiotics against infection caused by microorganisms has increased drug resistance. This has led to extensive research on plant compounds with antimicrobial properties and greater effectiveness as an alternative to antibiotics. The purpose of this study was to evaluate antibacterial activity the five Medicinal plant extracts <em>CinnamomumVerum</em><em>,</em><em> Zingiber officinale</em><em>,</em><em> Hibiscus </em><em>s</em><em>abdariffa</em><em>,</em><em> Berberis vulgaris</em><em>, </em>and <em>Mentha </em><em>p</em><em>ulegium</em> against standard bacteria: <em>Staphylococcus</em><em> aureus</em><em>,</em> <em>Staphylococcus </em><em>saprophyticus</em><em>, </em><em>E</em><em>ntrococcous</em><em> fecalis</em><em>, Pseudomonas aeroginosa,</em><em>A</em><em>cintobacter </em><em>bumani</em><em>,</em><em> K</em><em>lebsiella</em><em> pneumoniae</em><em>, </em>and<em> E</em><em>sherishia </em><em> coli</em><strong>.</strong></pre>
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<strong>Methods: </strong>The present experimental study was conducted in 2020 at Kurdistan University of Medical Sciences, Iran. The ethanol extract of the<em> Cinnamomum</em> <em>verum</em><em>,</em><em> Zingiber officinale</em><em>,</em><em> Hibiscus </em><em>s</em><em>abdariffa</em><em>,</em><em> Berberis vulgaris</em> and<em> Mentha </em><em>p</em><em>ulegium</em> were prepared by <a href="https://en.wikipedia.org/w/index.php?title=Skin_maceration&oldid=767108817">maceration</a> method<span dir="RTL">.</span>The antibacterial activity of the extracts was performed on several standard bacterial strains by <strong>a</strong><strong>gar well diffusion</strong> method after three replications and diameter of the zone of inhibition was measured and recorded<span dir="RTL">.</span> Then MIC (minimum inhibitory concentration) with Broth microdilution was determined. Mean growth zone diameter was analyzed by Duncan's comparison test at the 5% level.</pre>
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<strong>Results</strong>: In the present study, the highest antibacterial effect was related to <em>Berberis vulgaris </em>and<em> Zingiber officinale </em>extracts on <em>S. saprophyticus</em> with growth inhibition drops of 25 and 23 mm, respectively (p <0.05). <em>Hibiscus sabdariffa </em>extract on <em>S.saprophyticus</em> and <em>Mentha pulegium</em> extract on <em>E. coli</em> had the highest antibacterial effect with a growth halo diameter of 16, 13 and 13 mm, respectively (p <0.05). The highest antibacterial effect of cinnamon was on Staphylococcus aureus with a diameter of 19 mm. The lowest growth inhibitory concentration was observed for <em>Berberis vulgaris</em> and <em>Zingiber officinalis</em> extracts against <em>S. saprophyticus</em> with 3.1 mg / ml and lower than other types of extracts. <em>P. aeruginosa </em>showed resistance to most plant extracts (p<0.05).
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<strong>Conclusion</strong>: The results of the present study revealed that the plant extracts specially <em>Berberis vulgaris</em> had effective antibacterial activity on most of the bacterial strains. In order to show the optimal antibacterial effect of the studied extracts, it is suggested to study on the animal models and determine their clinical effects.</pre>
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آنتیباکتریال, دارچین, زنجبیل, چای ترش, زرشک, پونه کوهی, باکتریهای گرم مثبت, باکتریهای گرم منفی
Antibacterial Activity, Zingiber officinale Hibiscus sabdariffa, Berberis vulgaris, Cinnamomum verum, Mentha pulegium, Gram- Positive bacteria, Gram -Negative bacteria
717
730
http://armaghanj.yums.ac.ir/browse.php?a_code=A-10-1955-1&slc_lang=fa&sid=1
N
Ghadami
نرگس
قدمی
ghadanin@gmail.com
100319475328460022370
100319475328460022370
No
Department of Biology, Education District 1, Sanandaj, Kurdistan, Iran
گروه زیستشناسی ، ناحیه یک آموزش وپرورش سنندج ، کردستان ، ایران
N
Bahmani
نسرین
بهمنی
nasrinbahmani3@gmail.com
100319475328460022371
100319475328460022371
Yes
Zoonozvan Research Institute of Health Development Research, Kurdistan University of Medical Sciences, Sanandaj, Iran
مرکز تحقیقات زئونوز و انستیتو تحقیقاتی توسعه سلامت، دانشگاه علوم پزشکی کردستان، سنندج ، ایران
SH
Zandi
شیوا
زندی
sh_rainbow@yahoo.com
100319475328460022372
100319475328460022372
No
Water and Food Health Research Centers, School of Health, Kurdistan University of Medical Sciences, Sanandaj , Iran
مرکز تحقیقات بهداشت آب و مواد غذایی، دانشگاه علوم پزشکی کردستان، سنندج ، ایران