Armaghane Danesh

fa تغییرات سطح سرمی ارکسین A و شاخص‌های مقاومت به انسولین و آنتروپومتریک زنان دارای اضافه‌ وزن پس از شش هفته تمرینات هوازی Changes in Orexin A Serum Level, Insulin Resistance and Anthropometric Indices in Overweight Women after Six Weeks of Aerobic Training فیزیولوژی ورزش Sport Physiology پژوهشي Research چکیده زمینه و هدف: ارکسین یک پپتید ارکسیژنیک بوده و به صورت A و B در خون وجود دارد. نورونهای ارکسین به بعضی از پیام‌های سوختوساز که نشاندهنده وضعیت انرژی بدن هستند، پاسخ میدهند. این پژوهش به منظور تعیین اثر شش هفته تمرینات هوازی روی سطح سرمی ارکسین A، شاخصهای مقاومت به انسولین و آنتروپومتریک زنان دارای اضافهوزن انجام شد.   مواد و روش‌ها: در این مطالعه کارآزمایی بالینی، جامعه آماری را زنان دارای اضافه وزن و غیرفعال شهرستان بجنورد با دامنه سنی 45 تا 65 سال و نمایه توده بدنی 26 تا 29 کیلوگرم بر مترمربع تشکیل می‌دادند، از این میان 24 نفر که واجد شرایط بودند به روش نمونه‌گیری و به طور تصادفی در دو گروه 12 نفری کنترل و تمرین قرار گرفتند. برنامه تمرین، شامل تمرینات هوازی (با شدت 60 تا 70 درصد حداکثر ضربان قلب ذخیره) بود. تمرینات به مدت شش هفته و هر هفته سه جلسه انجام شد. داده‌ها با استفاده از آزمون‌های آماری شاپیروویلک، لون و آنالیز واریانس تجزیه و تحلیل شدند.   یافته‌ها: شش هفته تمرین هوازی باعث افزایش سطح سرمی ارکسین A، کاهش سطح سرمی انسولین، گلوکز، شاخص مقاومت به انسولین، وزن، نمایه توده بدن، نسبت دور کمر به لگن و درصد چربی در گروه تمرین شد، اما در گروه کنترل هیچکدام از این متغیرها پس از شش هفته تغییر معنیداری پیدا نکرد(05/0p<).   نتیجه‌گیری: شش هفته تمرین هوازی سبب افزایش سطح سرمی ارکسین A، کاهش مقاومت به انسولین و بهبود شاخصهای آنتروپومتریک در زنان دارای اضافه وزن میشود، لذا به زنان چاق توصیه میشود از این تمرینات به عنوان یک روش پیشگیرانه جهت بیماریهای دیابت و قلبی ـ عروقی آتی استفاده نمایند.        1.Oliveira A, Monteiro A, Jácome C, Afreixo V, Marques A. 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Medical Science Monitor: International Medical Journal of Experimental and Clinical Research 2012; 18(5): cr290. . ##                           <img alt="" height="62" src="data:image/png;base64,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" width="662" >Armaghane-danesh, Yasuj University of                                                                                   Original Article   <table cellpadding="0" cellspacing="0"> <tbody> <tr> <td height="54"> <table cellpadding="0" cellspacing="0" width="100%"> <tbody> <tr> <td> <div>1056</div> </td> </tr> </tbody> </table> </td> </tr> </tbody> </table>   <table cellpadding="0" cellspacing="0"> <tbody> <tr> <td height="54"> <table cellpadding="0" cellspacing="0" width="100%"> <tbody> <tr> <td> <div>1056</div> </td> </tr> </tbody> </table> </td> </tr> </tbody> </table> Medical Sciences Journal (YUMSJ)     Changes in Orexin A Serum Level, Insulin Resistance and Anthropometric Indices in Overweight Women after Six Weeks of Aerobic Training   Taheri G1, Fathi M2*, Mir E2   [1]Department of Sport Physiology, Bojnourd Branch, Islamic Azad University, Bojnourd, Iran, 2 Department of Sport Physiology, Ferdowsi University of Mashhad, Mashhad, Iran   Received: 10 Dec 2018          Accepted: 12 May 2019   Abstract                 Background & aim: Orexin is an orexigenic peptide present in the form of A and B in the blood. Orexin neurons respond to a number of metabolic signals that indicate the body's energy status. The present study was carried out to evaluate the effect of six weeks of aerobic training on orexin level, insulin resistance and anthropometric indices in overweight women.   Methods: In the present quasi-experimental study, the statistical population consisted of overweight and inactive women in Bojnourd, Iran,, aged 45-65 years, and BMI 26-29 kg/m2. Twenty-four eligible individuals were randomly divided into two groups of control and exercise. The exercise included aerobic training (with intensity of 60-70% of maximum heart rate reserve). The exercise performed three times per week for six weeks.   Results: The six weeks of aerobic training increased the orexin A level and decreased insulin, glucose, insulin resistance index, weight, BMI, WHR and fat percentage in interventional group. But in control group none of these variables changed significantly after six weeks(P<0.05).   Conclusion: The six weeks of aerobic training increased the orexin A level, decreased insulin resistance and improves anthropometric indices in overweight women. Therefore, obese women are recommended to use these exercises as a preventive method for future diabetes and cardiovascular diseases.       ارکسین, مقاومت به انسولین, تمرین Orxin, Insulin Resistance, Exercise 484 495 http://armaghanj.yums.ac.ir/browse.php?a_code=A-10-521-3&slc_lang=fa&sid=1 G Taheri گلناز طاهری ehsanmir90@yahoo.com 100319475328460018126 100319475328460018126 No Department of Sport Physiology, Bojnourd Branch, Islamic Azad University, Bojnourd, Ira گروه فیزیولوژی ورزشی، واحد بجنورد، دانشگاه آزاد اسلامی، بجنورد، ایران M Fathi مهرداد فتحی ehsanmir90@yahoo.com 100319475328460018127 100319475328460018127 Yes Department of Sport Physiology, Ferdowsi University of Mashhad, Mashhad, Iran گروه فیزیولوژی ورزشی، دانشگاه فردوسی مشهد، مشهد، ایران E Mir احسان میر ehsanmir90@yahoo.com 100319475328460018128 100319475328460018128 No Department of Sport Physiology, Ferdowsi University of Mashhad, Mashhad, Iran گروه فیزیولوژی ورزشی، دانشگاه فردوسی مشهد، مشهد، ایران