TY - JOUR JF - yums-armaghan JO - armaghanj VL - 26 IS - 2 PY - 2021 Y1 - 2021/4/01 TI - The Effect of Exercise Intensity and Saffron Supplementation on the Response of Insulin Resistance and Adipokine Markers TT - تأثیر شدت تمرینات ورزشی و مکمل یاری زعفران بر پاسخ نشانگرهای مقاومت به انسولین و آدیپوکاین‌ها N2 - Background & aim: Adipose tissue is not just a source of excess energy storage, but an endocrine organ that regulates biological functions by endocrine role by releasing adipokines that act like real hormones. The aim of this study was to investigate the effect of exercise intensity and saffron supplementation on the response of adipokines to insulin resistance markers in obese and overweight women. Methods: The present research method is quasi-experimental. Among obese and overweight women using G-Power software, 42 obese women with a body mass index above 25 were selected in a purposeful and accessible manner and randomly divided into six groups of intense intermittent exercise, continuous exercise, control, Intense intermittent exercise with saffron supplement, continuous exercise with saffron supplement and saffron supplement group were divided. After the initial sampling, the intervention groups worked for eight weeks. In order to eliminate the response of the last training session, blood sampling was performed 48 hours after the last training session. All data analysis was performed at a significance level of P≤0.05 with analysis of covariance. Results: There was a significant difference in the variables of weight, body mass index and fat percentage between the control group and training interventions and saffron (P<0.005). In the irizin variable, the results showed that there was a significant difference between periodic exercise + saffron, endurance + saffron with the control group (P=0.001). But there was no significant difference between the periodic training group + saffron and the endurance + saffron group (P= 0.9). In the lipocalin variable, the results showed that there was a significant difference between training interventions and saffron (except endurance training intervention) with the control group. The results also showed that there was no significant difference between the periodic training group + saffron and the intense periodic training group (P=0.7). The results also showed that there was no significant difference between the endurance group (P=0.1) and saffron (P=0.9) in the LDL variable compared to the control group. In the HDL variable, the only group that was significantly different from the control group was the intense periodic exercise group + saffron (P=0.03). In the cholesterol variable, the only group that was significantly different from the control group was the intense periodic exercise group + saffron (P=0.003). There was a significant difference in the triglyceride variable of the severe periodic group + saffron (P=0.001) and also the severe periodic group (P=0.03) with the control group. There is a significant difference in insulin and insulin resistance between all groups (except saffron) and the control group (P=0.001). The results also showed that there was no significant difference between insulin changes and insulin resistance between any of the exercise interventions (P=0.9). There was no significant difference in glucose between any of the groups (P=0.9). Conclusion: Saffron and higher intensity activity can have regulatory effects on the body's metabolic balance: The use of saffron and exercise improves the serum lipid profile and ultimately leads to improved insulin resistance. SP - 182 EP - 199 AU - Hasanvand, B AU - Mehrialvar, Y AU - Parsa, H AU - Heydarian, A AU - Erfani, F AD - Department of Physical Education and Sport Science, School of Literature and Humanities, Malayer University, Malayer, Iran, KW - High Frequency Intermittent Exercise KW - Endurance Training KW - Insulin Resistance KW - Glucose KW - Obesity UR - http://armaghanj.yums.ac.ir/article-1-2762-en.html DO - 10.52547/armaghanj.26.2.182 ER -