TY - JOUR T1 - The Effect of Aerobic Exercise on liver Factors in Antidote Producing Horses TT - تأثیر تمرینات هوازی بر فاکتورهای کبدی در اسب‌های تولید کننده پادزهر JF - yums-armaghan JO - yums-armaghan VL - 24 IS - 5 UR - http://armaghanj.yums.ac.ir/article-1-2536-en.html Y1 - 2019 SP - 922 EP - 934 KW - Aerobic exercise KW - Hepatic factors KW - Horse KW - Antidote N2 - Background & aim: Iran is one of the unique producers of antidote in the Middle East. The production of high-grade therapeutic serums and fewer side effects have a major impact on public health. Using sports activities as a non-pharmaceutical method can play an important role in maintaining and promoting animal health. The aim of the present study was to determine the effect of aerobic training on liver enzymatic factors aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP) and gamma glutamyl transferase (GGT) in horse breeding horses. Methods: In the present experimental study conducted in 2016, 16 horses in the antidote production cycle were randomly divided into two groups of venom and venom+training group for 22 weeks. The training protocol consisted of 3 sessions of aerobic exercise per week with moderate intensity. Blood samples were taken from weed vein at 3 different times: before the start of the protocol, at the end of the 11-week period, and at the end of the 22-week period. The activity of liver enzymes of AST, ALT, ALP, GGT was evaluated using Pars test kits manufactured using auto analyzer. Data were analyzed by Repeated Measure ANOVA with LSD test and SPSS 21 for data analysis at alpha level less than 0.05. Results: The data analysis indicated a significant decrease in the activity of ALP and GGT enzymes after 22 weeks of aerobic exercise training in the venom + training group (p=0.03). There was also a significant decrease in the activity of AST (p=0.02) and ALT (p=0.001) enzymes as a result of exercise training compared to the control group. Conclusion: According to the results of this study, aerobic training seems to be effective in promoting horse health and reducing the effects of venom by reducing the levels of liver enzymatic activity(AST, ALT, GGT, ALP) in antidote producing horses. Further research in this area is recommended. M3 10.52547/armaghanj.24.5.ضمیمه2.922 ER -