RT - Journal Article T1 - Analgesic and Anti-Inflammatory Effects of Hydroalcoholic Extract of Stachys Lavandulifolia Vahl s, Aerial Parts in Male Mice JF - yums-armaghan YR - 2011 JO - yums-armaghan VO - 16 IS - 2 UR - http://armaghanj.yums.ac.ir/article-1-401-en.html SP - 161 EP - 171 K1 - Analgesic K1 - Anti-inflammatory K1 - Hydroalcoholic Extract K1 - Stachys lavandulifolia Vahl AB - Introduction & Objective: In recent years, investigations on different species of Stachys have shown that extracts or components of this species exert various pharmacological effects including anti-inflammatory, antitoxic, antibacterial, antioxidant and cytotoxic effects. The aim of this study was to investigate the analgesic and anti-inflammatory effects of the aerial parts of the hydroalcoholic extract of Stachys lavanduifolia Vahl in male mice. Materials & Methods: In this experimental study which was conducted at Payam-e-Noor and Shahid Beheshti Medical University in 2009-2010, the analgesic effects of Stachys lavanduifolia Vahl in mice were studied, using the formalin and tail immersion tests. Also, the anti-inflammatory effects of this plant was studied in mice, using xylene-induced ear edema . Male NMRI mice, weighing, 20-25 g, were assigned into five groups: negative control (received 0.5% of aqueous solution of Tween 20), positive control in formalin test (received morphine, 10 mg/kg), positive control in xylene test (received dexamethason 15 mg/kg), and experimental groups. Experimental groups were intraperitoneally injected by 100, 200 and 400 mg/kg of hydroalcoholic extracts of Stachys lavanduifolia Vahl. Data were analyzed using SPSS software using ANOVA and post hoc Tukey test. Results: Results showed that all doses of Stachys lavandulifolia extract (100, 200 and 400 mg/kg), significantly (p LA eng UL http://armaghanj.yums.ac.ir/article-1-401-en.html M3 ER -