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Alfentanil Effects on Neonatal Apgar Score and Hemodynamic Changes of Pregnant Women that Underwent Caesarian Section in Response to Tracheal Intubation
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J Amjadimanesh   1, E Hatamipoor , H Ghfarian Shirazi , R Mombeini |
| 1- , dramjadimanesh@yahoo.com |
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Abstract: (4299 Views) |
| ABSTRACT:
Introduction & Objective: Caesarian section is the most common operation in gynecology field. Selection of anesthetic drugs for this operation needs so many considerations. Anesthetic drugs for this operation must prevent sever hemodynamic changes to tracheal intubation in mother and without side effects on neonate. This study was conducted to determine the effect of alfentanil given before induction of anesthesia on cardiovascular response to tracheal intubation in mother and Apgar score of neonate in Yasuj Emam Sajad hospital.
Materials & Methods: In this clinical trial 60 patients who were candidates for elective c/s delivery under general anesthesia , in ASA 1, without fetal distress, after taking knowledgably satisfaction for participant in study were allocated to 2 groups randomly. In both groups anesthesia induced by sodium thiopental, scholin and atracorium but in trial group alfentanil 5 µg/kg was given intravenously one minute before induction of anesthesia.
Results: Attenuated systolic blood pressure right after tracheal intubation and 5 minutes after tracheal intubation when compared with control group. Also in study group pulse rate of mothers had a smaller increase in comparison with control group. In this study systolic and diastolic blood pressure decreased 10 minutes after tracheal intubation but this decrease was less in comparison with control group. Apgar score of neonate in study group had not a meaningful difference in comparison with control group.
Conclusion: According to this study mothers who received alfentanil before induction of anesthesia had less increase in their systolic blood pressure and heart rates after tracheal intubation but systolic and diastolic blood pressure had decreased more in control group in comparison to trial group ten minutes after tracheal intubation. This phenomenon is due to more narcotic administration after delivery of neonate in control group. |
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| Keywords: KEY WORDS: Alfentanil, Anesthesia, Caesarian, Apgar score, Tracheal intubation |
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Full-Text [PDF 116 kb]
(995 Downloads)
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Type of Study: Research |
Subject:
Special
Received: 2015/06/10 | Accepted: 2015/06/10 | Published: 2015/06/10
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