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:: Volume 19, Issue 10 (1-2015) ::
__Armaghane Danesh__ 2015, 19(10): 852-860 Back to browse issues page
Evaluation of Analgesic effects of Clove Extracton Male Offspring of Surrey Female Miceduring Lactation
Kazem Hatami1 , Namdar Yousofvand 1, Sepideh Babaei Garmkhany1
1- Department of Biology, Razi University, Kermanshah, Iran
Abstract:   (7123 Views)
Background & aim: The analgesic effects of Clove plant is due to the presence of phenolic substances. Since no study has yet evaluated the analgesic effect of this plant extract during lactation, hencethe present study aimed to evaluate the analgesic effect of clove oil orally on offspringmalemiceduringlactation. 
Methods: Inthe present experimental study, two groupsoffemalemice, receiving cloveoil and control groupwere used. After delivery, animalsweretreatedorallywith cloveextract at the dose of 4% on the first day of delivery. In order toassess pain,formalin was used inmaleoffspringafterthirty daysofbirth. Data were analyzed using GraphPad prismstatistical software. 
Results: The results of this study showed that treating lactating female mice during lactation by clove oil induced analgesic effects of male offspring and this analgesia in the chronic phase of itself was shown significantly (P<0.01). 
Conclusions: Analgesic effectinduced byfeedingratswithcloveextractinmalemice possibly will be favorable inclinical usein the near future. 

Keywords: Eugenol, Clove plant, formalin test, NMRI mice
Full-Text [PDF 173 kb]   (1654 Downloads)    
Type of Study: Research | Subject: Special
Received: 2015/02/27 | Accepted: 2015/02/27 | Published: 2015/02/27
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Hatami K, Yousofvand N, Babaei Garmkhany S. Evaluation of Analgesic effects of Clove Extracton Male Offspring of Surrey Female Miceduring Lactation. armaghanj 2015; 19 (10) :852-860
URL: http://armaghanj.yums.ac.ir/article-1-75-en.html


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Volume 19, Issue 10 (1-2015) Back to browse issues page
ارمغان دانش Armaghane Danesh
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