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Effect of Aloe Vera Extract on Testicular Tissue of Embryo of Diabetic Rats
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M Jafari Barmak   , Z Khaksar 1 |
| 1- , Khaksar@shirazu.ac.ir |
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Abstract: (5916 Views) |
| Background & aim: Testis is an important organ of the male reproductive system and its structure could be influenced by diabetes. Aloe Vera has a hypoglycemic effect thus, the present study evaluates the effect of Aloe Vera on the testis tissue of a 20-day embryo of rat born from a diabetic mother.
Methods: Thirty female Sprague Dawley rats were randomly divided into three groups, subsequently two groups were injected with streptozotocin (50 mg/kg/IP) and the males were placed next to female rats in a separate cage in order to mate. One group of rats received aloe vera extract (400 mg/kg), orally, in gestational age during while others were giving distilled water. After 20 days, rats were sacrificed and their embryos were removed and fixed by 10% formalin. The embryos were processed and embeded in paraffin. Five µm sections were made and stained by hematoxyline- eosin and cellular alteration of testis was evaluated. Data were analyzed using one-way ANOVA.
Results: Mean of body weight, seminiferous tubules diameter, spermatogonia numbers, leydig cells and sertoli cells were significantly different in all groups (p<0.05).
Conclusion: The present study demonstrated that Aloe Vera extract can increase the spermatogonium, Leydig and Sertoli cells in diabetic rats. |
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| Keywords: Aloe vera, Testis, Diabetes. |
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Full-Text [PDF 800 kb]
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Type of Study: Research |
Subject:
Special
Received: 2015/04/26 | Accepted: 2015/04/26 | Published: 2015/04/26
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