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:: Volume 26, Issue 1 (3-2021) ::
__Armaghane Danesh__ 2021, 26(1): 90-103 Back to browse issues page
Association between umbilical cord blood laboratory findings with early onset neonatal sepsis
M Habibi1 , E Moradzadeh2 , M Fallahnejad3 , F Samieirad 4
1- Department of Pediatrics, Clinical Research Development Unit, Kowsar Hospital, Qazvin University of Medical Sciences, Qazvin, Iran
2- Department of Pediatrics, Qazvin University of Medical Sciences, Qazvin, Iran
3- Departments of Health, Razi Scholars Institute, Zanjan University of Medical Sciences, Zanjan, Iran,
4- Department of Pathology, Clinical Research Development Unit, Kowsar Hospital, Qazvin University of Medical Sciences, Qazvin, Iran , fsamieerad@gmail.com
Abstract:   (440 Views)
Backgrounds: Finding an efficient biomarker or combination of them as predictors of early-onset neonatal sepsis is very important. On the other hand, the use of umbilical cord blood samples in laboratory tests, along with its simplicity and availability, reflects neonate metabolic status.
 
Background and Aim: The aim of this study was to investigate the association between umbilical cord blood laboratory findings with early onset neonatal sepsis.
 
Materials and Methods: In this cross-sectional analytical study, we evaluated 180 neonates, 90 infants susceptible to early onset sepsis, and 90 healthy neonates who were admitted in neonatal and  neonatal intensive care unit wards, between January 2015 and 2016   at Kosar Hospital. The data from these participants were obtained by a check list including  gender,  birth weight, gestational age, white blood cell count, neutrophil counts, erythrocyte sedimentation rate (ESR), and reactive protein C (CRP) levels. Both descriptive and statistical analysis methods were applied. P value less than  0.05, statistically was significant. 
 
 
Results: Mean of ESR and neutrophil count in cord blood sample of suspected sepsis neonates was higher than well baby.  The mean of CRP levels in cord blood sample of suspected sepsis neonates slightly was higher than well baby. But there was no statistically significant difference between the CRP levels in both groups.
 
 
Conclusion: The results of this study showed that  the laboratory findings used in combination with each other as an early predictor of neonatal sepsis was  reliable.  
 

 
Keywords: Cord blood, Suspected early onset sepsis, Neonatal, Biomarker, Inflammatory.
Full-Text [PDF 1909 kb]   (23 Downloads)    
Type of Study: Research | Subject: Clinical laboratory
Received: 2020/08/12 | Accepted: 2020/10/3 | Published: 2021/03/2
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Habibi M, Moradzadeh E, Fallahnejad M, Samieirad F. Association between umbilical cord blood laboratory findings with early onset neonatal sepsis. Armaghane danesh. 2021; 26 (1) :90-103
URL: http://armaghanj.yums.ac.ir/article-1-2880-en.html


Volume 26, Issue 1 (3-2021) Back to browse issues page
ارمغان دانش Armaghane danesh
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