Background & aim: Reactive oxygen species are produced during acute exercise and caused cellular damage. Anti-oxidative intake may reduce oxidative stress by such exercises.Therefore, the purpose of the present study was to investigate the effect of short-term colostrum supplementation on serum levels of malondialdehyde and total antioxidant capacity induced by acute resistance on healthy men.

Methods: The present study was a quasi-experimental research and applied with a crossover design with an experimental group that was on a group of 10 healthy students aged 20 to 24 years of Birjand University which was designed to control individual differences. The researchers used quasi-experimental and cross sectional method with an experimental group. Subjects participated in resistance exercise training(80% of 1RM, 3 sets, 8-10 repetitions, recovery between sets and training respectively were 1 and 2 minutes). Blood sampling was performed 4 times, 2 times before colostrum intake and 2 times after colostrum intake. First blood sampling was performed before training and 12 hours of fasting. Second blood sampling was performed after resistance exercise training. After that, subjects received powdered colostrum(20 gr) every other day for two weeks. After two weeks of supplementation intake, final blood sampling was taken again. Shapiro-Wilk test was used for normality of data and ANOVA with repeated measure and LSD test were used to assess difference between pretest and posttest. Significant level was set at α<0.05.

Results: The results indicated that two weeks consumption of colostrum supplementation did not significantly change the malondialdehyde index(p=0.16), while total antioxidant capacity was significantly increased(p=0.01). p). But two weeks after short-term colostrum supplementation resulted in the decreas of the concentration of malondialdehyde index (p=0.001) and increased total antioxidant capacity (p=0.2) after a session of acute resistance exercise.

Conclusion: It seemed that colostrum may be used as a natural supplementation due to antioxidant properties and oxidative stress during acute resistance training, as well as body’s need vitamins and micronutrients imbalance supplement to reduce and inhibition of oxidative stress.