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Effect of Cucurbita pepo L. Fruit Pulp on Testis Histological Changes in Adult Rats
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M Mohsen pour   , M Shariati 1, A Esfandiari |
| 1- , mehrdadshariati@hotmail.com |
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Abstract: (4443 Views) |
| Background & aim: The Cucurbita pepo L. fruit pulp contains anti-oxidant, vitamins A, C and E, cucurbitacin, β-carotene and α-carotene, B complex vitamins, vitamin B6, pantetonic acid and contains minerals as well. The aim of this study was to evaluate the effect of pumpkin fruits on spermatogenesis and testicular tissue changes in male rats.
Methods: The present experimental study was conducted on forty adult male Wistar rats in four groups of ten. The control group received no drug treatment whereas the experimental groups were treated with 20, 40 and 80 percent of Cucurbita pepo L. fruit pulp orally for 28 days. At the end of the twenty-eighth day, the animals were operated and tissue sections were prepared after testes were removed. Histological changes between the experimental and control groups were examined by light microscopy. Using t-test, ANOVA and Tukey test data were analyzed.
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Results: The consumption of pumpkin fruit at amounts of 40 and 80 percent increase in the number of spermatogonia, primary spermatocytes and spermatids were (p <0.05). It also showed that at 80% increase in the concentration of spermatozoa in the seminiferous tubules was observed.
Conclusion: The results indicated that the pumpkin fruits containing ingredients such as cucurbitacin, pantothenic acid, vitamins and minerals that can increase testosterone level and improve the process of spermatogenesis. |
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| Keywords: Cucurbita pepo L. fruit, Tissue testis, Rat |
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Full-Text [PDF 530 kb]
(1873 Downloads)
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Type of Study: Research |
Subject:
Special
Received: 2015/04/8 | Accepted: 2015/04/8 | Published: 2015/04/8
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