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Eight-week aerobic training effects on Apelin-13 and insulin resistance in overweight men
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R Soori   1, MR Asad2 , M Yari2 , M Rastegar moghadan mansouri3 |
1- Department of Exercise Physiology, University of Tehran, Tehran, Iran , soorirahman@yahoo.com
2- Department of Exercise Physiology, Payame Noor University, Karaj, Iran,
3- Department of Exercise Physiology, Researcher of Iranian Research Center on Aging, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran. |
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Abstract: (5692 Views) |
Background & aim: Obesity as an epidemic which is associated with excessive accumulation of adipose tissue that secretes many hormones such as applein. Applein is an adipocytokine that increases its level in obesity. Changes in the level of apelin in response to aerobic exercise are not well defined. Therefore, the purpose of this study was to determine the effect of eight weeks of sub-maximal aerobic training with intensity of 50 to 60% of maximum heart rate on serum apelin-13 and insulin resistance in overweight men.
Methods: The present study was a quasi-experimental research. A total of 26 male overweight subjects with a body mass index of 27-30 kg / m2 were selected and randomly assigned to the subgroups and control aerobic exercise groups after the request was announced and adjusted to the entrance criteria. The aerobic training group under-maxed rrun out the training program for 30 sessions in an eight-week interval (3 sessions per week with an intensity of 50-70% of maximum heart rate).Body mass index, maximum oxygen consumption and blood sampling were performed and 24 hours after the last training session, the evaluations were repeated. Data were analyzed by statistical tests.
Results: The results of this study showed a significant decrease in body weight and body fat (p <0.05). Also, maximum oxygen consumption was significantly increased (p = 0.0001). However, indices of insulin resistance and Applein 13 did not show any significant changes. In addition, there was a direct and significant correlation between apelin 13 indices with anthropometric indices and glycosylated hemoglobin (p <0.05).
Conclusions: The internal factors of exercise practice, the intensity of aerobic exercise, have a significant effect on the anthropometric characteristics of overweight individuals, but not enough for significant changes in the levels of Applein 13 and insulin resistance. It is recommended that exercises be carried out over a longer period of time and more intensively so that the risk of developing type 2 diabetes and cardiovascular disease in people with overweight is reduced and controlled.
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| Keywords: Applein -13, Aerobic exercise, Insulin resistance, Overweight |
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Full-Text [PDF 3656 kb]
(1225 Downloads)
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Type of Study: Research |
Subject:
Sport Physiology
Received: 2016/10/17 | Accepted: 2017/07/8 | Published: 2017/07/25
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