2024-03-29T04:16:58+03:30 http://armaghanj.yums.ac.ir/browse.php?mag_id=31&slc_lang=en&sid=1
31-377 2024-03-29 10.1002
Armaghane Danesh armaghanj 1728-6506 1728-6514 10.61186/armaghanj 2013 18 1 Comparing the Efficacy and Adverse Effects of Tramadol and Sodum Diclofenac with pethedine in the Treatment of Renal Colic M Rajaei K Noorian noorian@skums.ac.ir Madineh S Madineh Abstract Background & aim: One of the choice treatments for pain relief in acute renal colic is administration of narcotics, but always the need for low-dose effects are felt difficulties. The aim of this study was to compare the efficacy of sodium diclofenac and pethedine hydrochloride with Tramadol to reduce the pain of acute renal colic. Methods: In this clinical trial study, 150 patients (15-65 years) with acute renal colic referred to Kashani hospital in Shahrekord were selected. The patients were randomly divided into 3 groups. The first group received 50mg tramadol intramuscular, the second group received 75mg D sodum iclofenac intramuscular and the third group (the evidence group) received 50 mg pethidin intramuscular. The pain severity was assessed before and then at 15, 30,60minutes after drug administration based on the McGill questionnaire. Data were analyzed with chi-square tests, ANOVA and Kruskal-Wallis tests. The pain severity of all parties on arrival to emergency ward and prior to the drug administration, and then 15, 30 and 60 min after the start of treatment were measured using a modified McGill questionnaire. Results: After drug administration (30.15 and 60 min), pain severity were decreased in all three groups. Minimum pain was seen in control where as the maximum pain was seen in tramadol group. Diclofenac have less side effects than pethedine (P<0.05). Conclusion: The finding showed that intramuscular Na Diclofenac due to its less adverse effects and more efficacy than tramadol is a suitable alternative to pethedine in treatment of acute renal colic. Key words: Pethedine, Tramadol, Diclofenac Na, Renal Colic Key words: Pethedine Tramadol Diclofenac Na Renal Colic 2013 4 01 1 9 http://armaghanj.yums.ac.ir/article-1-377-en.pdf
31-379 2024-03-29 10.1002
Armaghane Danesh armaghanj 1728-6506 1728-6514 10.61186/armaghanj 2013 18 1 Effect of 12-Week Pilates Trainning on EDSS in Women Suffering fromMultiple Sclerosis Z Shanazari shanazariz@gmail.com SM Marandi S Samie Abstract Background & aim: Multiple sclerosis is a debilitating disease that strikes the immune system. Multiple sclerosis is a chronic disease which debilitates the nervous system. The study was evaluated the effects of Pilates exercise on women with physical disabilities suffering from multiple sclerosis for 12 weeks .The aim of this study was to investigating the effects of Pilates trainning on EDSS of women suffering from Multiple Sclerosis (MS) for 12 weeks. Methods: In the present clinical trial study, 38 patients age 20-40 years (mean disease duration of 8±2 years) with multiple sclerosis grade 0-4.5 were selected. The Patients were randomly divided into two groups: experimental and control groups. The training program for pilates, 12 weeks, three sessions a week, with each session consisting of 60 minutes. Patients' physical disability was measured using Krutzke Expanded Disability Status Scale, before and after exercise. Data were analyzed by ANCOVA test. Results: Physical disability scores before and after the exercise in intervention was 47.1 and 37 and in the control group, was 93.1 and 43.1 respectively, which was significantly different in the intervention group before and after training (p<0.05). Conclusion: Pilates training improves the physical disability of MS patients. Therefore, this exercise can be used as a complementary treatment alongside drug treatments. Key Words: Multiple Sclerosis, Women, Pilates, EDSS Key Words: Multiple Sclerosis Women Pilates EDSS 2013 4 01 10 18 http://armaghanj.yums.ac.ir/article-1-379-en.pdf
31-380 2024-03-29 10.1002
Armaghane Danesh armaghanj 1728-6506 1728-6514 10.61186/armaghanj 2013 18 1 Effect of Bumble Bee Venom in the Treatment of Polycystic Ovary Syndrome, the Relationship Between Tissue Factor Affecting the Level of TNFα in the Wistar Rat Model M Nabiuni S Nasri F Poyanmanesh poyan_8311@yahoo.com Z Nazari Abstract Background & aim: Polycystic ovary syndrome (PCOS) is an endocrine failure leading to anovulation. TNFα is an effective factor in the regulation of normal functioning of the ovaries. High levels of TNFα causes PCOS is further. In this study, the effects of bumble bee venom (HBV) on TNFα and other symptoms of ovarian PCOS were studied. Methods: In this experimental study, 60 female Wistar rats were divided into three groups: control, sham and experimental groups. The experimental group was injected with estradiol valerate-induced PCOS direction. Induced rats (PCOS) were divided into two groups and treated with HBV. The treatment Group received 0.2mg of HBV for 10 consecutive days. Serum and ovarian tissue was collected from each of the four groups to compare the histological and changes in blood sugar levels. Results: A significant increase in ovarian PCOS weight was observed in the control group , whereas in the treated group with HBV rate fell (15.5 mg) Glucose levels in PCOS was 256.5, the control group138, and the treatment group 158. Thickness of the theca layer of antral follicles in the treated group compared with PCOS showed a significant decrease (110 μm and 150 μm respectively). Immunohistochemical results showed increased TNFα factor in PCOS group than in the control group, whereas these levels in samples treated with HBV Reduced. Conclusion: The results of this study revealed that the beneficial effects of HBV in PCOS may be due to the inhibitory effect on factor TNFα. Key words: Polycystic ovary syndrome, Bumble bee venom, Tumor necrosis factor, Immunohistochemistry Key words: Polycystic ovary syndrome Bumble bee venom Tumor necrosis factor Immunohistochemistry 2013 4 01 19 31 http://armaghanj.yums.ac.ir/article-1-380-en.pdf
31-381 2024-03-29 10.1002
Armaghane Danesh armaghanj 1728-6506 1728-6514 10.61186/armaghanj 2013 18 1 Antimicrobial activity of chamomile (Matricaria chamomilla L.) and feverfew (Tanacetum parthenium L.) Z Izadi SAM Modarres Sanavi modaresa@modares.ac.ir A Sorooshzadeh M Esna-Ashari P Davoodi Abstract Background & aim: The essential oil of chamomile (Matricaria chamomilla L.) and feverfew (Tanacetum parthenium L.) are frequently used in pharmaceutical and cosmetic industries. The aim of this study was to investigate the antimicrobial effect of the essential oils of chamomile and chamomile and feverfew. Methods: This experimental study was conducted in 2012 at Hamedan University of Medical Sciences. Essential oils of two medicinal plants species including chamomile and feverfew were obtained by hydrodistillation their constituents were analyzed by GC and GC/MS using retention indices and fragmentation patterns. The antimicrobial effects (MIC and MBC) of the essential oils were assessed on a number of microorganisms including gram positive and gram negative bacteria by microdilution technique. The interaction of plant essential oils against microorganisms through differential inhibition index was also evaluated. Data were analyzed by Duncan's multiple range test statistic Results: The minimum inhibitory concentrations of the oils were 0.22-4 and 0.09-1 mg/mlfor chamomile and feverfew respectively. Moreover, the combination of the plants essential oils confirmed synergistic against L. monocytogenes, B. subtilis and B. cereus and additive activities against S. aureus, E. coli and S. typhimorium. Conclusion: The results of this study showed that the application of these essential oils is recommended in combination as an efficients and complementary method for controlling microorganisms. Key words: Chamomile, Feverfew, Antimicrobial Effect Key words: Chamomile Feverfew Antimicrobial Effect 2013 4 01 31 43 http://armaghanj.yums.ac.ir/article-1-381-en.pdf
31-382 2024-03-29 10.1002
Armaghane Danesh armaghanj 1728-6506 1728-6514 10.61186/armaghanj 2013 18 1 The Effect of Atorvastatin on the Pancreatic Tissue of Male Rats M Karimian M Pourahmadi zahed1340@yahoo.com GA Jelodar F Mehrab Z Mohammadi ABSTRACT Background & aim: Statins are inhibitors drugs of hydroxymethyl glotaryl coenzyme A. In addition to decreasing plasma cholesterol, low-density cholesterol they reduce the rate of triglycerides. The aim of this study was to investigate the effect of atorvastatin on rat pancreatic tissue.In addition to decreasing the rate of plasma cholesterol concentration they also decrease the rate of LDL and Triglyceride. The aim of this study was to investigate the effect of atorvastatin on rat pancreatic tissue. Methods: In this study, 32 adult male rats were divided into four groups, control and three test groups. To conduct the present study, 32 male adult rats were divided into 4 equal groups: one control group and three test groups. Then the test groups were treated by Atorvastatin for 45 days with 10mg (group1), 20mg (group2) and 30 mg (group3) doses respectively. At the end of the treatment period, all rats were killed by taking blood from their hearts. The pancreas tissue of each rat (N=32) was separated. After fixation, tissue preparation and slide staining, Longerhans diameter was measured and number of cells was counted. Data were analyzed by t test.After fixing and coloring the tissue, all slides were prepared and evaluated under the microscope the diameter of I's of Longerhans and the number of cells. The data was analyzed through t-test. Results: There was no significant difference in the diameter mean of Longerhans between the test groups and the control group. The mean number of islets cells were increased in compared to the control group (P>0.05).There was also a significant increase was shown in the number of Longerhans cells in the test groups in relation to the control group (p (05/0>.(p>0.05). Conclusion: The consumption of the atorvastatine causes an increase in the number of Longerhans cells. In addition, the increase in the number of cells also increases the insulin secretion. As a result, blood sugar is decreased. Key Words: Atorvastatin, Pancreas, Rat Key Words: Atorvastatin Pancreas Rat 2013 4 01 44 49 http://armaghanj.yums.ac.ir/article-1-382-en.pdf
31-383 2024-03-29 10.1002
Armaghane Danesh armaghanj 1728-6506 1728-6514 10.61186/armaghanj 2013 18 1 The Effects of Intrahippocampus Injection of Almond oil on Passive Avoidance Learning and Memory in Adult Male Rat T Shahrivar AA Moazedi AA Rasekh S Almasi-Turk S Razmeh A Roozbehi aroozbehi@yahoo.com Abstract Background & aim: Almond oil contains compounds such asoleic acid, omega 3, 6, 9 polyunsaturated fatty acids and vitamin E. The aim of this study was to investigate the effects of intra-hippocampal injection of almond oil on passive avoidance learning and memory in male rats. Methods: In this experimental study, 56 male rats were randomly divided into 8 groups, including a control, 3 sailin groups which received normal saline 0.5, 1, 2 µl and 4 peanut oil groups which received 5/0, 1, 5/1 and 2 µl of oil.All groups, except the control, Groups except the control group were cannulated with stereotaxic surgery in the left CA1 region. One week after recovery, all groups were trained by shuttle box. Immediately after training, different doses of almond oil and saline were injected through the cannula in CA1 of hippocampus. After 48 hours, their Passive avoidance memory and learning were evaluated. Data were analyzed by ANOVA. Results: Almond oil doses of 0.5,1, 1.5 and 2 µg significantly improved passive avoidance learning and memory (P<0.05), but saline did not have. Conclusion: Almond oil as a steroid, effects on learning and memory and can improve learning and memory. Key Words: Learning, Memory, Almond oil, Hippocampus and Shuttle Box Key Words: Learning Memory Almond oil Hippocampus and Shuttle Box 2013 4 01 50 60 http://armaghanj.yums.ac.ir/article-1-383-en.pdf
31-384 2024-03-29 10.1002
Armaghane Danesh armaghanj 1728-6506 1728-6514 10.61186/armaghanj 2013 18 1 Prevalence of rotavirus in children hospitalized with acute gastroenteritis in Imam Sajjad Hospital of Yasuj, 2011 P Khodadadi pouya_khodadadi@yahoo.com M Kargar AA Moshfea AA H Ansari Abstract Background & Aim: Rotavirus infection is the most common cause of dehydrating and gastroenteritis among children worldwide. . The aim of this study was to determine the prevalence of rotavirus in children hospitalized with acute gastroenteritis in Imam Sajjad Hospital of Yasuj. Methods: This cross sectional – descriptive study was done on 184 stool samples of children younger than 7 years of age hospitalized at Imam Sajjad hospital of Yasuj in 2011 due to acute gastroenteritis. All samples were routinely analyzed for detection of rotavirus by Enzyme Immunoassay (EIA) test. Data was analyzed by SPSS version 16, Chi-square test and Fisher's exact test. Results: Of the 184 samples analyzed, 52(28.26%) were positive.The Results showed significant relationship between the seasonal distribution and virus detection (p=0/001). The highest incidence of rotavirus was seen in autumn with frequency of (48.08%) and the lowest in spring (5.77%). Conclusions: According to high prevalence of rotavirus infection, continual surveillance is necessary to provide useful data for formulating effective vaccines and perform diarrhea prevention programs. Key words: Rotavirus, Gastroenteritis, Prevalence, Elisa Key words: Rotavirus Gastroenteritis Prevalence Elisa 2013 4 01 61 68 http://armaghanj.yums.ac.ir/article-1-384-en.pdf
31-385 2024-03-29 10.1002
Armaghane Danesh armaghanj 1728-6506 1728-6514 10.61186/armaghanj 2013 18 1 A Case Report of a Patient with Leptospirosis O Ilami Z Zareie A Hadinia SZ Saeedinejad saeedizaker@yahoo.com Abstract Background & aim: Leptospirosis is a zoonosis of worldwide distribution. One of the most important diseases common to man and animals. The aim of this study was to report a case of a patient with leptospirosis. Case Report: A 32 year old man from the southern tropical city of Kangan due to high fever, muscle pain, eye redness, enlarged liver and spleen voltage and the physical examination, slight yellowing of the conjunctiva was referred to Shahid Beheshti Hospital of Yasuj. Initial treatment of the patient's fever and flu-like symptoms before the test was ordered by physicians with antibiotics and patients' vital signs such as fever were controlled. After testing many different diseases and suspect cases, leptospirosis was confirmed. Conclusion: There is a risk of leptospirosis in presence of rodents in tropical vector and also the ecological conditions. When flu-like symptoms, enlarged liver and spleen, jaundice and symptoms of kidney involvement disease and failure to respond to conventional treatments exist, suspected cases of leptospirosis should not be missed and therefore better diagnostic tests should be conducted. Keywords: Leptospirosis, Animal, Febrile, Flu Keywords: Leptospirosis Animal Febrile Flu 2013 4 01 69 75 http://armaghanj.yums.ac.ir/article-1-385-en.pdf
31-386 2024-03-29 10.1002
Armaghane Danesh armaghanj 1728-6506 1728-6514 10.61186/armaghanj 2013 18 1 Polymorphism in CCR4 Gene (1014 C/T) in Patients with Breast Carcinoma from the South of Iran F Moghaddasi MR Haghshenas S Naeimi naeimis@kau.ac.ir ABSTRACT Background & aim: CCR4 gene polymorphism at position C/T1014 has been associated with changes in mRNA stability and is involved expression of this molecule. The aim of this study was to investigate CCR4 gene polymorphism at position 1014 C/T in breast carcinoma patients in southern Iran. Methods: In this case-control study, 150 women with breast carcinoma and 160 healthy women as controls were included. PCR-RFLP method was used to genotyping of CCR4, receptor gene. The data were analyzed using chi-square and Fisher. Results: Genotype frequencies of CC, CT and TT, in case group were 57.8, 35.1 & 7.1%, where as in control group showed 54.4, 39.4 & 6.2% respectively. In addition, C and T allele of the cases were, 75.3 & 24.7% and in control group 74.1 & 25.9% respectively (p>0.05). Conclusion: CCR4 gene polymorphism has no role in increasing of susceptibility to breast cancer in the south of Iran population. Key words: Polymorphism, CCR4, Breast cancer Key words: Polymorphism CCR4 Breast cancer 2013 4 01 76 86 http://armaghanj.yums.ac.ir/article-1-386-en.pdf