2024-03-28T14:21:47+03:30
http://armaghanj.yums.ac.ir/browse.php?mag_id=119&slc_lang=en&sid=1
119-2427
2024-03-28
10.1002
Armaghane Danesh
armaghanj
1728-6506
1728-6514
10.61186/armaghanj
2020
25
3
The Effectiveness of Group Behavioral Activation Therapy on Chemotherapy-Induced Nausea and Vomiting in Women with Breast Cancer
Z
Farshidfar
z.farshidfar@yahoo.com
I
Rahimian Bogar
i_rahimian@semnan.ac.ir
J
Asadi
ardeshir.asadi@yahoo.com
P
Izadpanahi
dr.izadpanahi@gmail.com
Background & aim: Nausea and vomiting are among the most common and worrying side effects of treating breast cancer with chemotherapy drugs, which despite the advances in medical science, control of nausea and vomiting due to chemotherapy is still challenged. Therefore, the present study was conducted to investigate the effect of group behavioral activation therapy on nausea and vomiting due to chemotherapy in women with breast cancer.
Methods: The present clinical trial study was a quasi-experimental design with pretest-posttest and control group. The statistical population were all patients with breast cancer referred to Iranmehr Hospital in Birjand in 2018. Initially, a structured interview was conducted on 60 women with breast cancer referred to the hospital using the available method. At that point, 32 patients were selected by admission and randomly assigned to two groups. Data were collected through demographic questionnaires and nausea and vomiting due to chemotherapy (2016). The treatment protocol was based on the group behavioral activation pattern presented to the intervention group in 8 sessions of 120 minutes per week and the control group was placed on a waiting list. The obtained data were analyzed by multivariate analysis of covariance with SPSS-20 software.
Results: Mean post-test scores of severity subscales (p<0.05, F=84.148), duration (p<0.05, F=22.174), acute nausea and severity of acute vomiting (p<0.05, F=6.741) in the intervention group was significantly lower than the mean post-test scores of the control group, but no significant difference was obsereved between the mean scores of the post-test subscale of acute vomiting in the intervention and control groups after eliminating the pre-test effect (p= 0.019, p<0.05 and 765).
Conclusion: Group behavioral activation therapy significantly reduced the tensity/duration of acute nausea and the intensity of acute vomiting induced chemotherapy in women with breast cancer. Thus, this therapy can be a practical and promising treatment during chemotherapy.
Behavioral Activation
Nausea and Vomiting
Chemotherapy
Breast Cancer
2020
6
01
275
292
http://armaghanj.yums.ac.ir/article-1-2427-en.pdf
10.52547/armaghanj.25.3.275
119-2642
2024-03-28
10.1002
Armaghane Danesh
armaghanj
1728-6506
1728-6514
10.61186/armaghanj
2020
25
3
Evaluation of Cytotoxic and Apoptotic Effects of Simvastatin in Bone Cancer Cell line(MG-63)
MA
Soltani
aminsoltani787@gmail.com
T
Naji
tnaji2002@gmail.com
R
Ahmadi
rahahmadi@yahoo.com
Background & aim: Cancer is a mismatch between cell growth and death that results in excessive accumulation of cells. Bone cancer is a very serious type of cancer and occurs when osteoporotic cells have problems. The aim of this study was to evaluate the cytotoxic and apoptotic effects of simvastatin on bone cancer MG63 cell line.
Methods: In the present experimental study conducted in May 2017 in the Medical Sciences Branch of Islamic Azad University, MG63 cells were cultured and subsequently incubated with different concentration of simvastatin for 24 hours. Afterwards, the IC50 dose was measured using MTT assay. The effects of simvastatin on cell death mechanisms such as apoptosis and necrosis were evaluated by flow cytometry. PCR test was used to evaluate the gene expression of caspase 3, 8 and 9 enzymes. Finally, the cells were treated with IC50 dose of simvastatin and then examined by Hoochst flow cytometry staining technique. The collected data were analyzed using t-test.
Results: The results of MTT test indicated that simvastatin at a dose of 155 μg / ml killed 50% of cancer cells (IC50). On the other hand, flow cytometric evaluation revealed that MV63 cells treated with simvastatin (300 μg / ml) had more than 90% apoptotic cell death compared to the control group. Evaluation of caspase 3, 8 and 9 enzymes using real-time PCR technique displayed a significant difference in the expression of caspase 3 and 9 genes (p <0.001, but no significant difference was observed in the expression of caspase 8 gene (0.05). In Hochst staining technique, the discoloration of the cells in the treatment group compared to the control group indicated that the cell nucleus was dense and fragmented, which indicated apoptotic cell death.
Conclusion: Finally, the results of the present study revealed that simvastatin in cell culture medium can induce cytotoxic and apoptotic effects in bone cancer cells (MG63 cell line), therefore, it is important to consider the possibility of using simvastatin in the treatment of bone cancer.
Simvastatin
MG63 Cell Line
Bone Cancer
Caspase
2020
6
01
293
305
http://armaghanj.yums.ac.ir/article-1-2642-en.pdf
10.52547/armaghanj.25.3.293
119-2740
2024-03-28
10.1002
Armaghane Danesh
armaghanj
1728-6506
1728-6514
10.61186/armaghanj
2020
25
3
Evaluation of the Effects of Pentoxifylline on Stereological Changes in Frozen Ovarian Tissue of Mice
E
Kargar Abarghooei
Elyas.kargar@gmail.com
F
Karimi
karimi_fa@sums.ac.ir
F
Dehghani
dehghanf@sums.ac.ir
E
Rahmani Moghadam
ebrahimrahmani1374@gmail.com
M
Owrang
m.orang92@yahoo.com
E
Aliabadi
aliabade@sums.ac.ir
Background & aim: Ovarian cryopreservation is a technique in artificial insemination methods, while the ovary is vulnerable to the cryopreservation process. Pentoxifylline as an antioxidant takes a protective effect by reducing free radicals in culture medium. The aim of the present study was to determine and evaluate the antioxidant effects of pentoxifylline on stereological changes in frozen ovarian tissue of mice after freezing.
Methods: The present experimental study was conducted on 25 female ovaries at Shiraz University of Medical Sciences in 2019, which were randomly divided into five groups of five. Group 1 (control): No treatment was performed in this group. Groups 2 and 3 (sham 1,2): In Group 2, after the ovaries were removed, they were placed for half an hour in a CO2 incubator in the saline phosphate buffer + bovine serum albumin (PB1 + BSA) environment, And in Group 3, in addition to being placed in the incubator, 1.8 mM of Pentoxifylline was added to the buffer environment. Groups 4 and 5 (Experimental 1, 2): In Group 4, after the ovaries were removed from the animal's body, the ovaries were vitrified for two weeks, after which time they were melted and placed in a CO2 incubator for half an hour in the saline phosphate buffer + bovine serum albumin (PB1 + BSA) environment, and In Group 5, in addition to vitrified, melting, and incubation, the ovaries were exposed to buffers containing 1.8 mM pentoxifylline. After tissue processing, ovarian tissue sections were studied with stereological methods. Data were analyzed using SPSS software and Kruskal-Wallis statistical test.
Results: The stereological estimation indicated that the total volume of ovaries and cortex increased in control groups 2, experiment 1 and experiment 2 compared to the control group, but no significant increase was perceived (p<0.05). On the other hand, the volume of medulla in control groups 2, experiment 1 and experiment 2 decreased compared to the control group, but this decrease was not significant (p<0.05).
Conclusions: According to the results of the present study, pentoxifylline and cryopreservation increased the volume of ovarian tissue, but despite the antioxidant properties of pentoxifylline, no effect was observed on protecting the ovary from the negative effects of cryopreservation.
Ovary
Vitrification
Pentoxifylline
Mouse
2020
6
01
306
317
http://armaghanj.yums.ac.ir/article-1-2740-en.pdf
10.52547/armaghanj.25.3.306
119-2726
2024-03-28
10.1002
Armaghane Danesh
armaghanj
1728-6506
1728-6514
10.61186/armaghanj
2020
25
3
The Effect of Aqueous-Alcoholic Aerial Parts Extract of Dorema aucheri on Liposome Nanoparticles on Proliferation and Induction of Apoptosis in Human Colorectal Cancer Cells of SW48 Class
farzanehrezai@gmail.com
zahra.z.gh93@gmail.com
mtajali89@yahoo.com
hbardania@gmail.com
ghasem_ghalamfarsa@yahoo.com
Background & aim: Nowadays, plant extracts are used for research and clinical application in the treatment of cancers including colorectal cancer. Dorema aucheri plant has been conventionally used as an herbal medicine and its extract has been reported to contain significant amounts of antioxidants such as; Flavonoids, anthocyanins and phenolic acid. Therefore, the aim of the present study was to determine the effect of aqueous-alcoholic aerial parts extract of Dorema aucheri shoot on liposome nanoparticles on proliferation and induction of apoptosis in SW48 human colorectal cancer cell line.
Methods: The present experimental study was conducted in 2019 at Yasuj University of Medical Sciences. SW48 cells were cultured in vitro, and then treated with different concentrations of Dorema aucheri hydroalcoholic extract, Dorema aucheri -loaded nanoliposomes, liposomes alone for 24, 48, and 72 hours. The cytotoxic effect was assessed using MTT assay. Synthesis of nanoliposomes was formulated by lipid thin film filtration method. Apoptosis was measured by staining cells with propidium iodide and annexin V using flow cytometry. Vincristine was used as a positive control in the study. The collected data were analyzed using two-way ANOVA and Tukey's post hoc test. b
Results: The results of 50% inhibitory concentration (IC50) of Dorema aucheri nanoparticles and Dorema aucheri plant extract in 24 hours were 33.48 and 44.67 μg / ml, respectively, and for vincristine 50 ng / ml. The results indicated that the survival rate of cells was inhibited in a dose and time-dependent manner. The results of apoptosis test displayed that the highest percentage of increase in apoptosis in this cell line compared to the control was related to Dorema aucheri nanoliposomes (41.5%). On the other hand, Dorema aucheri extract alone had less increase than the control(p <0.05).
Conclusion: The results of te present study revealed that loading Dorema aucheri extract in nanoliposomes increased the toxicity and apoptosis effect of Dorema aucheri extract at low doses and could be a worthy candidate with less side effects for more extensive in vitro research.
Dorema aucheri
Apoptosis
Nanoliposome
SW48
2020
6
01
318
331
http://armaghanj.yums.ac.ir/article-1-2726-en.pdf
10.52547/armaghanj.25.3.318
119-2650
2024-03-28
10.1002
Armaghane Danesh
armaghanj
1728-6506
1728-6514
10.61186/armaghanj
2020
25
3
The Effect of Eight Weeks of Circuit Resistance Training and Spirulina Supplementation on Plasma Levels of Irisin and Some Body Composition in Overweight and Obese Men
K
Dehghani
Karimdehghani320@ birjand.ac.ir
M
Mogharnasi
mogharnasi@birjand.ac.ir
M
Saghebjoo
m_saghebjoo@birjand.ac.ir
H
Sarir
hsarir@ birjand.ac.ir
M
Malekaneh
drmalkane@ bums.com
Background & aim: One of the appropriate ways to control overweight and obesity is regular training and the benefit of antioxidant supplements. The purpose of the present study was to investigate the effect of eight weeks of Circuit resistance training and spirulina supplementation on plasma levels of Irisin and some body composition indices in overweight and obese men.
Methods: The present single blind quasi-experimental study with double blind method, 60 overweight and obese men (BMI>25) aged 30-55 years were purposefully selected and randomly divided into four groups: training + Spirulina, training + placebo, spirulina, and placebo. The intervention and placebo groups consumed two 500-mg capsules of spirulina and placebo for eight weeks, respectively. Resistance training was performed for eight weeks, three sessions a week, and 12 movements as: very light, light, medium and heavy intensities with rest intervals (actively) between stations and shifts of 1, 1-2 and 3-5 minutes were administered. Body composition indices, body weight, BMI, and WHR were measured before and after training using a combination gauge. Subjects were fasted for 12 hours in two stages (pre- and post-test) of 10 ml blood from antecubital left bra vein. The data were analyzed using Shapiro-Wilk tests, one-way ANOVA, LSD and t-test at (α<0.05).
Results: Plasma levels of irisin and body weight indicated a significant difference between groups (p<0.05). In the intergroup study, the plasma levels of irisin in the training+spirulina, training+ placebo groups increased significantly(p<0.05), but body weight, BMI in the training+ spirulina, training+placebo and spirulina groups, and WHR values in the training+Spirulina, training+ placebo decreased significantly(p<0.05). Plasma levels of irisin, body weight, BMI and WHR in the placebo group did not change significantly(p>0.05).
Conclusion: It seemed that eight weeks of Circuit resistance training with spirulina by increasing plasma levels of Irisin and reducing body weight, BMI, and WHR supplementation significantly improved the body composition and obesity-related disorders.
Overweight
Obese
Irisin
Circuit resistance training
Spirulina
2020
6
01
332
345
http://armaghanj.yums.ac.ir/article-1-2650-en.pdf
10.52547/armaghanj.25.3.332
119-2336
2024-03-28
10.1002
Armaghane Danesh
armaghanj
1728-6506
1728-6514
10.61186/armaghanj
2020
25
3
The effect of a period of selected physical activities on improving gross motor skill in children with hearing disorder
P
Moghimifar
parisa.mogh@yahoo.com
M
Sheikh
mortezahomayoun@gmail.com
R
Hamiat Taleb
rasool.hemayat@yahoo.com
M
Homayounia Firoozjah
mortezahomayoun@gmail.com
S
Nazari Kakundi
saednazari@yahoo.com
Background & aim: Motor skills are the driving force of human growth and development. Pre-school and primary school ages are important developmental periods that require special attention in motor skills training. The aim of this study was to determine and evaluate the effect of a selected exercise program course on improving gross motor skills of children with hearing impairment in Amol city.
Methods: The present research was a quasi-experimental study using pretest-posttest design. The statistical population included all students with hearing impairment in Amol city who were studying in the academic year 2011-2012. Sixteen participants were selected based on the available sample and demographic questionnaire. Participants were randomly divided into two homogeneous groups of 8 as control and experimental groups based on the pre-test scores of the general motor skills test. The participants of the experimental group performed parts of the selected Spark training program for 18 sessions. The participants in the control group performed their usual activities. Data were analyzed using Kolmogorov-Smirnov and multivariate covariance tests.
Results: The findings of the present study indicated that the experimental group performed better than the control group in all subscales, especially gross motor skills, such as jumping and licking skills (P≤0.05). The selected movement program indicated a significant difference between the experimental and control groups in the two skills of jumping and licking with statistically high power (P≤0.01). The square of ETA was related to the displacement of 0.51. In effect, the impact rate was 51%.
Conclusion: The results of the present study revealed that the performance of selected physical activity had a significant effect on the subtests of mobility skills and object control in children with hearing impairment. The results indicated that by presenting a selected educational program, it was possible to provide an opportunity for the development of object control and movement skills, which were the basis of specialized and sports skills in children.
Selected Physical Activity
Hearing Impairment
Coarse Motor Skills
2020
6
01
346
359
http://armaghanj.yums.ac.ir/article-1-2336-en.pdf
10.52547/armaghanj.25.3.346
119-2591
2024-03-28
10.1002
Armaghane Danesh
armaghanj
1728-6506
1728-6514
10.61186/armaghanj
2020
25
3
Relationship of Mother\'s Hypertension, Age and Drug Use with Neonates Hyperbilirubinemia
N
Mirazi
mirazi205@gmail.com
A
Seif
erfan.seif@gmail.com
F
Zarei
B.bahrevar@chmail.ir
N
Pezeshki
pezeshki@umsha.ir
Z
Izadi
armaghan.izadi@gmail.com
Background & aim: Neonatal hyperbilirubinemia is most common reason to re-admission in hospital. The mother's basic disorders are access and effects on this phenomenon. The aim of this study is to determinate and relation of hypertension, age and drug addiction in mothers on neonatal hyperbilirubinemia.
Methods: In this analytical descriptive study which done in 2018, the 300 mother's documents which refer to hospital for hospitalization their babies were studied. The questionnaire regarding maternal and their neonates were completed. Mothers and neonates information, degree of icterus, mother's hypertension and drug addiction history, family icterus history, kind of delivery, mother and neonate body weight, familiar wedding and number of labor were collected and evaluated. All data were evaluated statistically by SPSS and MINITAB method .
Results: The results of this study showed that the affection chance in neonates with mother's 21-30, 31-35 years old and 36 years old and up compare to neonates with their mothers under 20 years old (reference sheet) were about 2.95, 2.15 and 1.92 manifold respectively. The affection chance for hyperbilirubinemia in neonates with their mothers which have hypertension was 4 manifold compared to neonates with normal mothers. The affection chance for hyperbilirubinemia in neonates with their preterm mothers (less than 38 weeks) was 1.76 manifold mothers with complete term( more than 38 weeks). The affection chance for hyperbilirubinemia in neonates with their mothers which delivered naturally 1.56 manifold compared to mothers which labored her babies by cesarean section. There is to calculate probability of hyperbilirubinemia in neonates with using of predictive alternatives of mother's age in delivery time, pregnancy hypertension, pregnancy age and type of delivery with logistic regression presentation
Conclusion: This study explained that the mother's age in delivery time, pregnancy hypertension, age of gestation and type of labor have effects on neonatal hyperbilirubinemia. The fitting of logistic regression model on studying data and optimization operations showed that the mother's age under 20 years, without hypertension, term gestation and cesarean delivery have reduce hyperbilirubinemia probability to 26% in neona
Neonatal Hyperbilirubinemia
Hypertension
Age
Logistic Regression
2020
6
01
360
373
http://armaghanj.yums.ac.ir/article-1-2591-en.pdf
10.52547/armaghanj.25.3.360
119-2761
2024-03-28
10.1002
Armaghane Danesh
armaghanj
1728-6506
1728-6514
10.61186/armaghanj
2020
25
3
Prevalence of Second Canal in Mandibular Incisors in CBCT and Periapical Radiography
A
Sardarian
sadra.sardarian@yahoo.com
SH
Torabi
shiva72torabi@gmail.com
SH
Shahidi
sholehshahidi@yahoo.com
S
Ghodsi Bushehri
shahr.ghodsi@gmail.com
Background & aim: Accurate knowledge of root canal morphology is essential for standard endodontic treatment. Mandibular incisor teeth are usually single-rooted and single-canal, but sometimes have a second canal that, if left untreated, can lead to failure of endodontic treatments. Therefore, the aim of the present study was to determine and compare the accuracy of periapical radiography with CBCT in observing the second channel in mandibular incisors.
Methods: The present study was a cross-sectional analytical research and fitted to correlation schemes in terms of data collection and analysis methods. The statistical population consisted of 292 periapical radiographs and CBCT of mandibular incisor teeth in 73 patients (including 41 females and 32 males). All patients were required to prepare these images for their treatment process. Radiographs were evaluated by two trained dental students in axial, coronal and cross-sectional sections. The number of lower incisors and their shape were recorded according to Vertucci's classification for dental canal morphology. If there was any disagreement between the two students, the radiologist was consulted to make the final decision. Data were analyzed using t-test.
Results: CBCT examination indicated that 78.4% of mandibular incisors were single-canal and in the rest two-channel, but in periapical radiographic examination none of the teeth exposed the presence of two channels. Central teeth had more cases of two canals than lateral and male teeth compared to women. In Vertuchi classification, among the two-canal teeth, the highest prevalence was related to type four (6.4%) and the lowest prevalence was related to type three (4%).
Conclusion: Although periapical radiography is a routine procedure for endodontic treatment, CBCT radiography should be used when endodontic treatment fails or a second canal is present.
Mandibular incisor
CT scan
Second canal prevalence
Periapical radiography
2020
6
01
374
383
http://armaghanj.yums.ac.ir/article-1-2761-en.pdf
10.52547/armaghanj.25.3.374
119-2454
2024-03-28
10.1002
Armaghane Danesh
armaghanj
1728-6506
1728-6514
10.61186/armaghanj
2020
25
3
High Frequency of Biofilm Related Genes (IcaD, FnbA, IcaA and ClfA) Among Staphylococcus aureus Isolated From Bovine with Subclinical Mastitis
Mansouri
F
fariba.mansouri75@gmail.com
SS
Khoramrooz
khoramrooz@gmail.com
M
Mahmoudi- Mourderaz
y.mahmody@gmail.com
M
Marashifard
masoud.marashifard@gmail.com
SAA
Malek Hosseini
malekhosseini91@gmail.com
Background & aim: Regarding to the importance of S. aureus colonization in bovine mastitis and the role of biofilm in its pathogenesis, the aim of this study was to determine the phenotypic production of biofilm and subsequently identify genes related to biofilm production in isolates of S. aureus from bovine with subclinical mastitis.
Methods: In the present cross-sectional study, a total of 502 milk samples were collected from bovine with subclinical mastitis in Boyerahmad and Dena townships. After isolation of bacteria was completed, the detection of nucA gene by PCR method was conducted for the final confirmation of S. aureus. Congo Red Agar plate was used for the assessment of biofilm production. The PCR method was used for the detection of icaA, icaD, fnbA, clfA, cna and bap genes. The collected data was analyzed by the SPSS software version 15 and chi-square test.
Results: A total of 80 (15.9%) isolates of Staphylococcus aureus were isolated, of which 55 (68.7%) isolates were able to form biofilms. The highest frequency of icaD gene was identified in 87.5% of isolates and bap gene with the lowest frequency (5%). Significant association were observed between biofilm production and presence of icaD(p=0.0001), icaA(p=0.003), fnbA(p=0.0001) and clfA(p=0.0001).
Conclusion: Considering the important role of biofilm in development of antibiotic resistance and high frequency of biofilm producer isolates, this finding should be considered as an alarm. Hence, the biofilm production helps the bacterial colonization and the pathogenesis could lead to economical and healthcare burden on the community.
Staphylococcus aureus
Biofilm
Biofilm Related Genes
Mastitis
2020
6
01
384
397
http://armaghanj.yums.ac.ir/article-1-2454-en.pdf
10.52547/armaghanj.25.3.384
119-2725
2024-03-28
10.1002
Armaghane Danesh
armaghanj
1728-6506
1728-6514
10.61186/armaghanj
2020
25
3
Species Diversity and Relative Abundance of Medically Importance Flies in Golestan Province, 2018-19
M
Hossinzadeh
manuchehrhosseinzadeh@yahoo.com
SF
Motevali Haghi
haghi77@yahoo.com
M
Fazeli Dinan
AA
Enayati
A.enayati@mazums.ac.ir
K
Akbarzadeh
kamran.akbarzadeh@yahoo.com
J
Yazdani Charati
jamshid.charati@gmail.com
O
Dehghan
omid_dehghan21@yahoo.com
Background & aim: Flies are important in the region in terms of mechanical transmission of pathogens, sciatica and forensic entomological research. Identification of species in different regions is the first and most important way to control vector-borne diseases in the region. Therefore, the aim of the present study was to determine the diversity of species and relative abundance of flies of medical importance in Golestan province during 2018-2019.
Methods: In the present descriptive study, the samples included medically important flies, which were sampled in both urban and rural areas, including eight stations in Ramyan city in 2018. Trapping was done monthly, on sunny days and on the hottest day of the month. Entomological nets and cone traps were used to catch adult flies. Species identification was performed based on valid keys. The collected data were analyzed using Microsoft Excel software.
Results: In the present study, 10 species of Musca domestica (housefly) (53.75), Muscina stabulans (7.26), Lucilia ceasar (14.39), Lucilia sericata (7.91), Calliphora vicina (8.95), Sarcophaga africa (1.55), Sarcophaga aegyptica (0.51), Calliphora vomitoria (3.48), Sarcophaga argyrostoma (0.75), Muscina levida (0.18) in three family including Muscovidae, Sarcophagidae and Acrostida were captured. The most abundance of flies were observed in garbage collection sites and animal places. Musina levida species was reported for the first time from northern Iran in this study. Based on the results of temperature and humidity fluctuations, it was established that the higher temperature and decreasing humidity, the more abundance of flies’ population were obsereved.
Conclusion: Due to the high abundance of flies in waste collection sites and animal sites, rapid transfer of non-residential areas and their sanitary burial is necessary to reduce the population of flies. It is necessary to move animals out of residential areas and provide health advice to people and health centers on diseases transmitted by flies in the warmer months of the year.
Diptera
Muscidae
Sarcophagidae
Species Diversity
2020
6
01
398
409
http://armaghanj.yums.ac.ir/article-1-2725-en.pdf
10.52547/armaghanj.25.3.398
119-2657
2024-03-28
10.1002
Armaghane Danesh
armaghanj
1728-6506
1728-6514
10.61186/armaghanj
2020
25
3
Assessment of Transvaginal Ultrasonography Accuracy in the Diagnosis of Uterine Pathologies in Women with Abnormal Uterine Bleeding
Z
Tavoli
z.tavoli@tums.ac.ir
H
Azizi
hossein.azizi1994@gmail.com
S
Moradpanah
zmoradpanah@gmail.com
R
Hashemi
Rezvan.hme@gmail.com
A
Montazeri
montazeri@acecr.ac.ir
Background & aim: The most common cause of abnormal uterine bleeding in women of childbearing age is structural disorders of the uterus. There are several methods for assessing abnormal uterine bleeding, such as transvaginal and hysteroscopic ultrasound. The aim of this study was to determine the accuracy of transvaginal and hysteroscopic ultrasound in diagnosing uterine lesion in women with uterine fibroids.
Methods: The present cross-sectional study fits into correlation schemes in terms of data collection and analysis. The primary study population was 119 women between 20 to 50 years of age with abnormal uterine bleeding undergoing transvaginal ultrasonography and hysteroscopy for therapeutic and diagnostic purposes, from which 109 patients matched the entrance criteria. Patients with exclusion criteria (obesity, underemployment) Thyroid) were excluded from the study and the diagnostic accuracy of transvaginal ultrasound for the diagnosis of lesions such as uterine polyps, submucosal myomas, normal and endometrial hypertrophy and endometrium without lesions with hysteroscopic findings in the form of positive, positive values, characteristics. The likelihood ratio was compared and evaluated. Data were analyzed using Chi-square and Fisher tests.
Results: Ultrasound and hysteroscopic findings in this study indicated that the most common causes of abnormal uterine bleeding were; uterine polyps and submucosal myomas, endometrial hypertrophy. Sensitivity of transvaginal ultrasound for the above three findings were: 58.9%, 72.2% and 51.7% respectively. The specificity of this method for diagnosing these lesions were; 76.8%, 78.5% and 86.4% respectively.
Conclusion: The final results indicated that the diagnostic accuracy of transvaginal ultrasound was significantly lower than that of hysteroscopy in the diagnosis of uterine polyps, submucosal myomas and endometrial hypertrophy.
Ultrasonography
Hysteroscopy
Abnormal Uterine Hemorrhage
2020
6
01
410
418
http://armaghanj.yums.ac.ir/article-1-2657-en.pdf
10.52547/armaghanj.25.3.410
119-2841
2024-03-28
10.1002
Armaghane Danesh
armaghanj
1728-6506
1728-6514
10.61186/armaghanj
2020
25
3
-
-
-
Ghafari.mehdi@gmail.com
This article is not an abstract
-
2020
6
01
419
422
http://armaghanj.yums.ac.ir/article-1-2841-en.pdf
10.52547/armaghanj.25.3.419