1 1728-6506 Yasuj University Of Medical Sciences 434 Special Evaluation of mexiletine effect on duration of sensory and motor block in spinal anesthesia with lidocaine Haghbin M Askarzadeh MR Sharifzadeh M Shabani M 1 5 2014 19 2 100 110 04 05 2015 04 05 2015 Abstract Background & aim: The methods to increase duration of spinal anesthesia is always noticed.,the aim of this study was to investigate the effect of mexiletine on duration of sensory and motor block in spinal anesthesia. Methods: In a clinical trial study 60 patients with age 18-50, ASA 1,2 who were scheduled for lower limb elective surgery at Shahid Bahonar hospital were enrolled. They were randomally assigned in two groups of control and intervention. Intervention group received oral mexiletine 200 mg 2hours before operation and control group received placebo.Spinal anesthesia was carried out with lidocaine /5 (100mg) in L2-L3 or L3-L4 space by the same method in two groups. Pulse rate,Pulse oximetry and mean arterial blood pressure were recorded in two groups every 5-10 minutes.Also the duration of sensory and motor block was recorded. The results were analyzed with Student t-test,Chi square and Mann-Whitney. Results:The onset of sensory and motor block was significantly faster in intervention group.(P<0/01) The duration of sensory and motor block was significantly more in intervention group than control.(P<0/001) The pulse rate in intervention group were signifigantly less than control group in 0,5,10,60,75 minutes after spinal injection. (P<0/05) Conclusion: Mexiletine is effective in increasing duration of sensory and motor block in spinal anesthesia with lidocaine and also increases the onset of both sensory and motor block with lidocaine. Key Words: Mexiletine, Sensory and motor block, Spinal anesthesia, Lidocaine
437 Special The Effect of High Intensity Interval Training and Common Continuous Training on Health-Related Quality of Life in Cardiac Patients with POST-CABG Gaeini AA Satarifard S Heidary A 1 5 2014 19 2 111 123 04 05 2015 04 05 2015 Abstract Background & aim: Quality of life decreases in cardiac patient and there is a little information about the effect of interval training on this matter. The aim of this study was to compare the eight weeks of high intensity interval training with common continuous training on health-related quality of life in cardiac patients with post-coronary artery bypass graft. Methods: In this clinical trial, 30 cardiac patients of Tehran Heart Center that CABG surgery was done on them were randomly divided into two groups high-intensity interval training and continuous moderate-intensity training (program common). The program of interval group was included 4rep × 4 min at 90-95% HRpeak and continuous group 60-80 minute at 70-85% HRpeak, three sessions per week for 8 weeks. Quality of life was assessed based on the SF-36 questionnaire before and after the training program. The collected data were analyzed using the one way ANOVA test. Results: Physical function, social function, mental health and vitality were significantly increased following the both of training programs (p<0.05). Physical function and social function after high-intensity interval training was more than moderate intensity continuous training (p0.05) Conclusion: It seems that, high-intensity interval training program will not only does not be a threat to cardiac patients post-coronary artery bypass graft surgery, but it is more beneficial than moderate intensity continuous training in some parameters of the quality of life such as physical function and social function. Keywords: Exercise, Quality of Life, Cardiac Patients Post-CABG 441 Special Evaluation of Protective Effects of Crocin Onembyo Developing Process in in Vitro Fertilization (IVF)in Cyclophosphamide Treated Mice Khan Mohammadi F Shahrooz R Ahmadi A Razi M 1 5 2014 19 2 124 135 04 05 2015 04 05 2015 Abstract Background & aim: Cyclophosphamide (CP) along with therapeutic role, exert the effects such as an immunosuppressant agent, induce oxidative stress, impact gonadal cell’s DNA and reducing the fertilizing potential. The present study was aimed to evaluate the protective effects of crocin, on IVF embryos development following chemotherapy with CP. Methods: In this study 36 adult female mice, aged 6-8 weeks, divided into 3 groups and treared for 21 days. The control animals received saline normal (0.1ml/day, IP), and sham control group received CP alone (15 mg/kg/week, IP) and experimental group received crocin (200mg/kg/day, IP) along with CP (15 mg/kg/week, IP). After the end of treatment period PMSG and HCG were administrated for stimulating the ovulation process. The sperms were obtained from 6 adult male mice. Following the euthanizing of animals, and oocyte along with normal sperm collection in-vitro fertilizing was performed by using HTF+4mg/ml BSA medium. The fertilized oocytes were incubated for 120 hours and embryos were studied in various stages. All data were analyzed statistically by Minitab software. Results: In sham control group a significantly reduction in suitable oocytes, percentage of fertilization, two cells zygote, blastocysts and increase the number of arrested developing embryos observed in comparison to control group, and administration of crocin caused significantly increase in suitable oocytes, percentage of fertilization, two cells zygote, blastocysts and significantly reduction of arrested developing embryos in comparison to sham control group (P<0.05). Conclusion: The co-administration of crocin with CP chemotherapy caused a significant improvement in fertilizing potential and promoted the embryo development. Key words: Cyclophosphamide, Crocin, Mice, Oocyte, In vitro fertilizing 442 Special The effect of Teucrium Orientale on Oxidative Stress marker and Liver Function Enzymes in Streptozotocin-Induced Diabetic Rats Tahmasebpour N Dehghan GH Hosseinpour Feizi MA Monirinasab H 1 5 2014 19 2 135 145 04 05 2015 04 05 2015 Abstract Background & aim: Diabetes is a metabolic disorder characterized by hyperglycemia resulting from perturbation in insulin secretion, action or both. The aim of this study was to investigate the effects of methanol extract of Teucrium orientale on blood glucose and liver damage markers in streptozotocin diabetic rats. Methods: In this experimental research 32 male albino Wistar rats, with body weights of 200 – 240 g were randomly allocated into four groups with 8 rats per each. Control group (normal rats), diabetic rats (received STZ in single dose 60 mg/kg bw, intraperitoneal way and without receive extract), treated normal rats (received T. orientale 200 mg/kg bw, oral gavage) diabetic treated rats (received STZ in single dose 60 mg/kg bw, intraperitoneal way and received T. orientale 200 mg/kg bw, oral gavage). Afterwards 21 days, blood glucose, malondialdehyde (MDA) in liver and the activity of the liver enzymes (ALT ،AST،ALP( were evaluated. The collected data were analyzed using SPSS software via the one-way ANOVA. Resulths: This study demonstrated that sSerum levels of glucose in T. orientale treated diabetic group (222 ± 9.8) were significantly lowerdecreased than in comparison with diabetic ratsgroup (572 ± 8) (P < 0.01).The MDA level in T. orientale treated diabetic group (1.01 ± 0.04) were significantly decreased in comparison with diabetic rats (1.25± 0.54) (P < 0.05). The ALT, AST and ALP levels in T. orientale treated diabetic group were also significantly decreased compared with diabetic rats (P < 0.01). Conclusion: Methanol extract of T. orientale had antidiabetic effects and consequently might alleviate the liver damage caused by streptozotocin-induced diabetes mellitus. Keywords: Diabetes, Teucrium orientale, ALT, AST, ALPLiver enzymes, streptozotocin 443 Special Depression and Sub-clinical Markers of Multiple Sclerosis Salehpoor GH Kafi SM Rezaei S Hosseininezhad M Salehi I 1 5 2014 19 2 146 160 04 05 2015 04 05 2015 Abstract Background & aim: Multiple sclerosis is a chronic neurological disease that depression has been found in more than 40% of its patients and by several sub-clinical markers associated with disease the opportunity will appearance. Aim of this present study was investigation depression and multiple sclerosis sub-clinical markers. Methods: In this analytical cross-sectional study, 162 patients with multiple sclerosis were selected by consecutive sampling and using the clinical and demographic variables inventory, Depression, Anxiety and Stress Scale, Short Form Health Survey questionnaire, Fatigue Severity Scale along with identical analog-spring balance were examined. The data were analyzed by pearson correlation coefficient, one way analysis of variance, Tukey's test and stepwise multiple regression. Results: Patients with 3 or more times the number of relapses and hospitalizations experienced, received significantly more depression scores than patients with lower frequent relapse and hospitalization. In addition, sub-clinical markers of the disease together could explain 30% of the shared variance of depression. Overall in final step limitations due to physical problems, fatigue and bodily pain could significantly predicts depression scores in patients (P <0.0001). Conclusion: This study highlighted the impact of multiple sclerosis sub-clinical markers in depression of patients. Hence, is requirement that identified key predictors of this research be considered as possible risk factors in development of depression associated with multiple sclerosis and used for the regular management of the disease. Key words: Multiple Sclerosis, Depression, Fatigue, Pain 444 Special Formative Research to Study the Viewpoints, Attitudes and Driving Behaviors in Taxi Drivers of Yasuj: The First Step in Planning of an Intervention Based on Social Marketing Model Maleki M Mohammadi S Shariatinia S Shams M Abedirad A Nasiri R Koohgard S Akaran MJ Kazem F Zamani SH 1 5 2014 19 2 161 178 04 05 2015 04 05 2015 Abstract Background & aim: Formative research is done to identify and analyze the related factors for a behavior and determining an initiative idea for intervention. This study aimed at knowing about viewpoints of taxi drivers in Yasuj and assessing attitudes and behaviors in driving. In this way, a behavioral intervention will be designed for decreasing risky driving behaviors. Methods: This cross-sectional study including qualitative and quantitative on taxi drivers in Yasuj. In qualitative part, data were explored from 16 drivers in two focal group discussions and in quantitative survey, a questionnaire is used for measuring attitudes and self-reported behaviors and a checklist is used for recording observational behaviors of 260 taxi drivers. Descriptive and analytical statistics for quantitative were used. All discussions with taxi drivers were recorded, categorized and analyzed and its findings summarized in five main themes. Results: Majority of taxi drivers had desired attitudes toward risky driving behaviors. More than 80 percent reported that always or most times avoid doing risky driving. However, observation showed that not fastening seatbelt through route is the most frequent behaviors among taxi drivers. In focal group discussions, four themes and few sub-themes were explored and the main recommendations for reducing risky driving behaviors were continuous education, road modification, increasing police supervision and using route supervisors as opinion leaders of taxi drivers. Conclusion: Determining frequent risky driving behaviors, attention to viewpoints of drivers and selecting segments based on influencing factors on their behaviors can be effective for reducing risky driving behaviors. Key words: Formative research, Risky driving behaviors, attitude, Taxi drivers, Social marketing 445 Special Salmonella contamination of eggs of native Kohgiluyeh va Boyerahmad using PCR1 techniques and the evaluation of drug resistance Monadi M Kargar M Naghiha A Mohammadi R 1 5 2014 19 2 179 187 04 05 2015 04 05 2015 Abstract Background & aim:Foodborne disease, a major health and economic problem in industrialized and non-industrialized countries.The purpose of this study was to investigate Salmonella contamination of eggs by native province kohgiloyeh va Boyerahmad by PCR and evaluation of their drug resistance. Methods: This cross-sectional study-descriptive study of 210 eggs collected from native Kohgiluyeh va Boyerahmad done. Biochemical tests for identification of bacteria was isolated. Salmonella bacteria have suspected reactions were tested by PCR with specific primers invA genes were examined. Results: The results showed that 14 number of eggs (6/66 percent) were contaminated with Salmonella genus. Dehdasht area of highest contamination and less pollution Charusa areas, Dyshmuk, Lndeh and was Basht And no significant correlation was found between the type and extent of contamination and the region.The antibiotic resistance of most resistance to penicillin (100%) was observed.This study uses data from the nineteenth and application soft ware spss version microsofte office 2007-square test and Fisher were analyzed. Significant level of p>0/05 was considered. Conclusion: Microbial agents such as Salmonella can cause food spoilage and disease are. Resistance in Salmonellais recommended to avoid the in discriminate use of antibiotics in live stock and poultry should be avoided. Key words: Salmonella,Egg,drug resistance, invA, PCR. 446 Special A study of the relationship between emotional intelligence, academic achievement and depression among students of Medical sciences university of Yasuj,2012 Rezanejad MR Rezanejad Nourian KH Gafarian Shirazi HR Hasanzadeh N 1 5 2014 19 2 188 194 04 05 2015 04 05 2015 Abstract Background & aim: Emotional intelligence is the ability to control the emotions of oneself, of others, to distinguish between emotions of oneself and the others and to use these information to conduct of thoughts and actions. Methods: The study of Emotional Intelligence Inventory (EQI) and Beck Depression Scale for Students (USDI) and also to evaluate the difference in the academic achievement of medical science GPA of 300 students during the academic term was used. Data were statistically analyzed using ANOVA, t-tests and descriptive statistics (mean ± SD) were analyzed. Results: Between emotional intelligence and depression was correlated with academic success (p< 0/05). Also, 80 percent of students had moderate and good emotional intelligence and only 12/3 of an EI were great. Results indicate that 67/7% of the students suffered from depression. Conclusion: Students learn and improve emotional intelligence can decrease anxiety and improve academic achievement it was. Keywords: emotional intelligence, depression, academic achievement