@article{ author = {Jahangiri, Z and Abdolvahab, M and Bagheri, H and Jalili, M and Baghestani, AR}, title = {The Effects of Static Anti-pronation Splint on Activities of Spastic Hemiplegic Children}, abstract ={Background & aim: Cerebral palsy is a common cause of disability in childhood that effects on posture and motor development and leads in activity limitation. In these children, the function of hand and arm become problematic and this can lead to disability in doing of activities of daily living. Orthosis and splints are used to improve position, range of motion, hand function and finally can improve doing of activities in children. The aim of this study was to investigate the effects of static anti-pronation splint on activity, spasticity, range of motion, and function of affected hand of spastic hemiplegic children of 8-12 years old. Methods: The present single blind randomized control trial study was conducted on 20 spastic hemiplegic cerebral palsy children with 8 to 12 years old who were selected through students who studied in physical disabled schools in Tehran, Iran. Patients were randomly divided into intervention and control group. Patients in the intervention group used a static anti-pronation splint for two months, 6 hours daily. Duration of using the splint was 3 sets of 2 hours a day. In this study, the Activity Scale for Kids was used to evaluate activity implementation of children, the Modified Ashworth Scale was used to assess spasticity of wrist, forearm and elbow, ROM of wrist, forearm and elbow were tested with goniometer and Box & Block test was used to evaluate hand function. Results: The results in intervention and control group were interpreted and compared together. Results in intervention group showed a significant improvement in activities of children (p<0.002), wrist`s spasticity (p<0.005), forearm`s spasticity (p<0.003), wrist`s ROM (p<0.001), Forearm ROM (p<0.003) and hand function (p<0.001). The data did not show significant improvement on elbow`s joint ROM (p<0.343) and spasticity (p<0.157).In control group, significant improvement did not seen (p>0.05). In comparing the results of intervention and control group, before the study there was not a significant difference between two groups, but after study, the difference was significant. Conclusions: Information from present research shows that using static anti-pronation splint for 2 months, 6 hours a day, can be an effective method to improve activity implementation, wrist and forearm spasticity and range of motion and hand function in hemiplegic CP children.}, Keywords = {Cerebral palsy, Activities of children, Static anti-pronation splint, Spastic hemiplegic}, volume = {21}, Number = {1}, pages = {1-13}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1150-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1150-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Broomand, S and Taherianfard, M}, title = {Interaction of Bisphenol A and Passive Avoidance Learning on Dopamine D1 Receptor Distribution in Accumbens and Caudate Putamen Nuclei in Male Rats}, abstract ={Background & aim: exposure to Bisphenol A (BPA) produces a significant increase in levels of the dopamine D1 receptor mRNA throughout the brain. Accordingly, the aim of present study was to investigate the effect of BPA on dopamine D1 receptor distribution in accumbens (aca) and caudate putamen (cpu) nuclei in with and without learning of male rats. Methods: In the present experimental study, thirty male rats weighting 220- 300 g were used. Animals were divided into 6 groups, that each with 5 male rats. BPA in doses 5 and 50 mg/kg/day were used by oral intake for 15 days. Learning and memory were performed by a passive avoidance shuttle-box. Distribution of dopamine D1 receptor was investigated by immune-histochemical procedure. For determination of color difference the software of Image Analyzer were used. For data analysis, One-way ANOVA test and Tukey test as post-hoc were used (P<0.05). Results: Data in the present study showed that BPA in two dose significantly (P<0.05) decrease distribution of dopamine D1 receptor in aca nucleus relative to sham2 of male rats with learning. BPA in two dose significantly (P<0.05) decrease distribution of dopamine D1 receptor in cpu nucleus relative to sham1 and 2 of male rats with and without learning. Distribution of dopamine D1 receptor in aca and cpu nuclei significantly (P<0.05) higher in sham 2 compared to sham1group.  Conclusion: According to present results, BPA impair dopamine D1 receptor distribution in aca and cpu nuclei of male rats, while the BPA in learned animal has not significant effects on dopamine D1 receptor distribution.}, Keywords = {BPA, passive avoidance learning, shuttle-box, dopamine D1 receptor, male rats}, volume = {21}, Number = {1}, pages = {14-26}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1065-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1065-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Taheri, S and Mirazi, N}, title = {The Effect of Elettaria cardamomum L. Fruit\'s Hydroethanolic Extract on Thyroids Hormones Serum Level in Hypothyroid Male Mice}, abstract ={Background & aim:  Thyroid gland has an important role in growh and metabolism in the body. Hypothyroidism is a disorder that act on body organs. Medicinal plants are widely used in treatment of disease. Elettaria Cardamomum L.is known as a medicinal plant widely used in traditional medicine. In the present study, the Elettaria Cardamomum hydroethanolic extract (ECE) on hypothyroid male mice was investigated. Methods: In the present experimental study, 42 male mice were randomly divided into 6 groups: control groups, witness (taking propylthiouracil ,PTU 0.1% in tap water), treated groups 1,2 and 3: (taking PTU, 0.1% in tap water + 100, 200 and 400 mg/kg ECE , i.p) and levothyroxine group (taking PTU, 0.1% in tap water + 15 µg/kg. gavaged). The PTU 0.1% was administered for 15 days, then the groups received ECE and levothyroxine for 10 days. The control group received 0.25ml normal saline intraperituneally daily. At the end of experiment, animals were anesthetized by ether and blood samples were collected from heart directly for analyzing TSH, T3 & T4 hormones. The data were expressed as mean±SEM and analyzed by ANOVA statistical software (P<0.05). Results:The results of this study indicated that the T3 and T4 levels decreased and TSH level increased significantly compared with the control group in taking PTU group(P<0.001). In treated groups by ECE with different concentrations the T3 and T4 serum levels increased significantly compared with the witness group (P<0.001). Moreover, the T3 and T4 serum levels increased significantly in the levothyroxine group compared with the control and hypothyroid groups(P<0.001).  Conclusion: The ECE may have antioxidant and flavonoid compounds which are able to act on thyroids hormones synthesis considerably and increase its serum levels in male mice. }, Keywords = { Hypothyroidism, Elettaria cardamomum, T3 &,,amp, T4, mice}, volume = {21}, Number = {1}, pages = {27-39}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1170-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1170-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Banitalebi, E and CheraghCheshm, M and Faramarzi, M}, title = {A Comparison of the Effect of Conventional Exercise and Locomotor Training Quality of Life in Incomplete Paraplegic Individuals}, abstract ={Background & aim: There are various treatment methods, such as land-based training, hydrotherapy,  locomotor training with bodyweight support and functional electrical stimulation after spinal cord injury. Therefore, the aim of this study was to compare the effect of conventional exercise and locomotor training quality of life in incomplete paraplegic persons. Methods: In the present quasi-experimental study, 17 voluntary paraplegic spinal cord injured volunteer participants were selected by availability. The participants were randomly assigned to locomotor group (N=10) and conventional exercises group (N=7). The participants were trained for 12 weeks, four sessions per week and 60 min per session. Locomotor sessions included 15 min warm-up on fixed gear bike, 45 min locomotor with 50% body weight and 10 min cold-down finally. 10% load was added each week. Traditional exercises sessions included 15 min warm-up plus 45 min stretch exercise and resistance training. The first samples were taken 24 h before the first session and the second samples were taken 48 h after the last session (after 12 weeks). Results: The data revealed that in the locomotor training group, there was significant reduction in serum BDNF in comparison to traditional training group. The data indicated that there were significant differences physical functioning (P = 0.039), role-physical (P = 0.001), bodily pain                     (P = 0.001), general health (P = 0.001), vitality (P = 0.001),  social functioning(P = 0.001),  role-emotional (P = 0.001), mental health (P = 0.001), between locomotor and conventional exercise groups. On the other hand, there were no significant differences in terms of physical (P = 0.313) and mental (P = 0.257) quality of life between two groups. Conclusions: The results displayed that in some aspects of quality of life were observed significant differences between the two types of rehabilitation intervention, but overall both practice and effective achievements in improving the quality of life for people with paraplegia with the same.}, Keywords = { Locomotor exercises, Quality of Life, Incomplete Paraplegia}, volume = {21}, Number = {1}, pages = {40-56}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1033-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1033-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {AfshonPour, MT and Habibi, AH and Ranjbar, RA}, title = {Effects of Continuous Aerobic Exercise Training on Plasma Concentration of Apelin and Insulin Resistance in Type 2 Diabetic Men}, abstract ={Background & aim: Apelin is a newly discovered adipokine which plays an important role in regulation of energy homoeostasis and improvement of insulin resistance. The aim of this study was to determine the effect of continuous aerobic exercise on plasma concentration of apelin and insulin resistance in type 2 diabetic men. Methods: In the present quasi-experimental study, twenty four diabetic men from Ahwaz, Iran, were selected and randomly divided into training (n=12) and control (n=12) group. Anthropometric measures, body composition and maximal oxygen uptake (VO2max) of the subjects were measured by using a modified Bruce continuous aerobic exercise training was performed during 8 week (3 session per week, 20-45 min per session, 40%- 70% HRmax). Before, and 48 hours after the last training session, plasma concentration of glucose, insulin and apelin were measured and HOMA-IR was calculated. Data analysis was used by T-tests, ANOVA and Pearson correlation coefficient and the significant level of p<0/05 was considered. Results: There was a statistically significant decrease in plasma concentration of glucose and insulin and HOMA-IR, and a significant increase in plasma concentration of apelin was observed in training group compared with pretest and control group. Furthermore, a significant negative relationship between plasma concentration of apelin and HOMA-IR after 8 weeks aerobic training was found. Conclusion: It seems that low to moderate intensity continuce areobic exercise training has significant effect on the amount of plasma apelin in type 2 diabetic men. Continuous aerobic exercise may be effective in improving the insulin resistance and glycemic control in type 2 diabetic men.}, Keywords = {Adipokine, Apelin, Insulin resistance, Type 2 Diabetes, continuce Aerobic Exercise}, volume = {21}, Number = {1}, pages = {57-70}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1148-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1148-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {SalehiGatabi, A and Zaboli, F}, title = {Antibiotic Resistance Pattern and Existence of Beta-Lactamase SHV, TEM, CTX-M Genes in ESBL-Producing Klebsiella Strains in the Clinical Samples in Babol, Iran}, abstract ={Background & aim: Resistance to Extended Spectrum Beta-Lactamase (ESBL) is one of the most widespread enzymatic beta-lactamase in those bacteria which cause infections in hospitals. One major reason for this type of resistance seems to be the arbitrary and/or excessive use of antibiotics. At present, there is no resistance pattern for bacterial strains which cause infections in hospitals with ESBL mechanism in different regions of Iran, they spread differently in different seasons, and more and more cases of the resistance are being reported. Hence, the present study aimed to determine the antibiotic resistance patterns and bacterial strains and to investigate the presence of Beta-lactamase SHV, TEM , CTX-M genes in those Klebsiella strains which produce ESBL. The clinical samples of the study were collected from Yahyanejad Hospital in Babol.  Methods: The present descriptive-analytical study was carried out in six-months in 2014, and  2075 clinical samples( of blood, urine, respiratory discharge, throat culture, wound culture, pleural fluid culture, CSF, Ascitic fluid culture, Synovial culture, and bone marrow smear) were gathered. 39 Klebsiella strains were identified among the hospitalized and out-patients of Yahyanejad Hospital using disk diffusion method and CLSI instructions. Antibiotic allergy tests were given for all the strains, and all the strains were separated using synergic double discs to check the presence of ESBL. In the next phase of the study, the extracted DNA were examined in terms of the presence of SHV, TEM , CTX-M by using specific primers and employing PCR method. The collected data were analyzed using, SPSS and K2 tests. Results: The frequencies of the identified strains were: isolated Klebsiella Pneumonia: 31(79.49%), isolated Klebsiella Oxytoca: 5(12.82%), and isolated Klebsiella Ozaenae: 3(7.69%). Among  the isolated Klebsiella stains  19(48.72%) were resistant to cefotaxime , 14(35.90%) to ceftazidime, 18(46.16%) to Amikacin, 13(33.34%) to Meropenem, 18(46.15%) to Ciprofloxacin, 26(66.67%) to Ceftriaxone, 12(30.77%) to Piperacillin Tazobactam, and 16(41.03%) to Ampicilin sulbactam. Also, among the 39 isolated Klebsiella Pneumonia, there were 10(25.64%) isolated positive ESBL,  all the 10(100%) isolated strains  having Beta-Lactamase SHV gene, there were 6(60%) isolated positive TEM gene and there were 4(40%) isolated positive CTX-M gene. Conclusion: Considering the high rate of resistance to third generation cephalosporin, it is imperative to perform accurate antibiogram and avoid irrational prescription of antibiotics in treating infections due to organisms which produce ESBL. In addition, it is of vital importance to screen the clinical samples in terms of resistance to ESBL, and to prepare guidelines for physicians to help realize the disease and to treat the patients properly. Also , the extracted DNA were examined samples purified in identifying genes SHV ,TEM  ,CTX-M in Klebsiella Pneumonia is possible PCR method.}, Keywords = {Klebsiella Pneumoniae, Antibiotic resistance, Extended Spectrum Beta lactamase (ESBL), Polymerase Chain Reaction.}, volume = {21}, Number = {1}, pages = {71-83}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1063-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1063-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {afrouz, S and Ghatee, MA and Zoladl, M and Sangtarash, MH and Avazpour, AR and Azizi, A and Ghalehgulab, MR and Prysaye, Z and Jamshidi, A}, title = {Study of prevalence of Thalassemia and comparison of hematological indices in types of Thalassemia in marriage candidate patients in Kohgiluye & Boyerahmad province in 1392}, abstract ={Background & aim: Thalassemia is an inherited autosomal recessive anemia caused by structural variations or abnormalities in globin chain synthesis. The screening of thalassemia in marriage candidates is a suitable opportunity for prevention and control of this disease. Regarding hematologic indices variations in above-mentioned patients, this study was conducted to compare the hematological indices variations in types of Thalassemia in marriage candidate patients in Kohgiluye & Boyerahmad province in 1392. Methods: In the present cross-sectional study, the results of the genetic analysis by GAP-PCR method and hematological indices including MCV, MCH, HGA2 and RBC of  111 thalassemic marriage candidates who referred to health centers, along with their demographic data was analyzed with descriptive statistics and inferential statistics آنوا and Pearson correlation, by the SPSS software version 17.   Results: Alpha thalassemia (78/4 percent), non-alpha-beta thalassemia (9 percent) and beta thalassemia (8.1 percent) were the most frequent types, respectively. The average of hematological indices were 2/77 ± 0/75, 75/62 ± 5/58, 23/87 ± 2/40 5/61 ± 0/62 for HbA2, MCV, MCH and RBC, respectively. Alpha thalassemia patients showed higher MCV average in comparison to beta thalassemia cases. The difference of average of MCV between patients with alpha-thalassemia and patients with non-alpha/beta was not statistically significant. MCV average in Beta thalassemia was not different with both Alpha thalassemia and non-alpha/beta thalassemia. MCH and HgA2 difference between different thalassemia types was matched with MCV but RBC average difference was not significant for any types of thalassemia. There was a direct significant correlation between MCV and MCH for all types of thalassemia. MCV and MCH indices averages have inversely correlated with RBC In patients with alpha thalassemia (p =0/01). Conclusion: the difference of average blood parameters including MCV, MCH and HgA2 between beta thalassemia cases with alpha, non-alpha-beta thalassemia patients with beta thalassemia cases, and beta thalassemia with both alpha and non-alpha-beta thalassemia can be used as a predictive marker for clinical diagnosis types of thalassemia among Kohgiluye and Boyerahmad province patients.}, Keywords = {Alpha thalassemia, Beta thalassemia, Blood indices}, volume = {21}, Number = {1}, pages = {84-94}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1238-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1238-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Jabbari, AR and Azizzadeh, M and Keyvanara, M and Rahi, F}, title = {The Consequences of Medical Services Tariffs Reform from the Perspective of Health Managers, a Qualitative Study}, abstract ={Background & aim: Medical services pricing is one of the most important tools of each country's health system policy makers. Tariff is effective on equity, efficiency, quality and accountability in the provision of services. Switch medical services tariffs affected providers of hospital and medical services income on the one hand, and on the other hand the cost of medical and hospital care providers of financial resources. The aim of this study was to obtain results and consequences of tariffs substantially reform from the health managers' point of views. Methods: The present qualitative descriptive cross-sectional study was conducted from 2013- 2014. The research population was 12 Health Managers of Tehran, Isfahan and Tabriz who were investigated with deep interview. Analysis of the data was based on a thematic analysis. Criteria such as "reliable information", "trustworthy", "reliability" and "ability to consolidation" of data were considered. Results: According to findings, the results of the study were divided into two categories: positive and negative consequences as a result of medical services tariff reforms and likely increase, although logically and scientifically. The positive consequences included; behavioral outcomes, economic and stakeholder satisfaction. And negative consequences include; economic consequences and limited group dissatisfaction. Conclusion: The consequences have been anticipated at the time of modification of medical tariffs in addition to encouraging health tariff and policy makers Because of the benefits that will be earned in terms of positive consequences, they noticed negative consequences, particularly in economic consequences and the need to provide for an increase in tariffs and the need to think for provides financing compensatory.}, Keywords = { right tariffs, medical tariffs, reform, consequences}, volume = {21}, Number = {1}, pages = {95-106}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1056-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1056-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Radnia, N and Otogara, M and Sajadi, F and Hosseinirad, S}, title = {Uterine Ruptures as a Result of Misoprostol in a Case Study of a Primigravida Woman}, abstract ={Aim & Objective: Our purpose was to report the experience of uterine rupture in a primigravida patient with uterine anomaly for whom misoprostol is used for induced abortion in the second trimester. Misoprostol is a synthetic analogue of E1 prostaglandin which is used to prevent the ulcer peptic causing NSAID. Case study: A 19 year old woman with prime gravid with epigastric pain was referred to the hospital by a gynecologist and was put under the portable ultrasound but the fetal heartbeat was not audible in the suprapubic region, and given the free fluid in the abdomen at 12 weeks of pregnancy and a lot of free blood with a diagnosis of hydrops a legal abortion license was granted to her. At 16 weeks of gestation and admitted to the hospital within 48 hours due to the use of misoprostol and oxytocin, and in accordance with the protocols, due to no signs of bleeding and expansion, she was eventually discharged from the hospital. Once again she referred to the hospital in 48 hous and the mentioned procedures was done once more but the abortion did not succeed. 18 days after the last admission, she was once was once again referred to the hospital with the sign of acute stomach pain. The emergency care unit conducted the necessary procedures. Using sonography, peritoneal is dignosed, and she underwent a laparoscopy. The surgeon removed the placenta and fetus from the abdominal cavity, and when examining the uterus, and uterine rudimentary horn with a septum was observed to be incomplete for the patient during surgery. Conclusion: although uterine rupture is rarely followed by the usage of Misoprostol, it is of great importance to take into consideration the irrecoverable complications which compel us undertaking vital cautions and also make sure of the normality of uterine before prescribing Misoprostol.}, Keywords = {Uterine Rupture, Misoprostol, Gravidity}, volume = {21}, Number = {1}, pages = {107-113}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1075-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1075-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Shojaei, B and SamaniJahromi, E and ZolghadriJahromi, S}, title = {Protective effect of para aminopropiophenone on the testosterone and gonadotropin hormones changes upon gamma ray radiation in adult male rats}, abstract ={Introduction: In the recent decades, many researches have been conducted to prevent destructive effects of gamma-ray on the body tissues. One of these researches is the use of radio-protector before radiation. In this study, we examine para-amino propinophenone (PAPP) effects, as a radio-protector, on the variations of Gonadotropin and testosterone. Materials and Method:In this experimental study, 70 adult male rats were studied. They were randomly divided into 10 septet groups. Control group received food and water; and no more experimental material was given or fed. Sham group receivedsolvent(ethanol 96%). Groups3,4 and 5 received10, 20, 40 mg/ kg of PAPP were injected. Group 6 was influenced by gamma-ray (2greys). Group 7 were given 1ml ofethanol and after a half an hour were influenced bygamma-ray (2greys).Groups8, 9 and 10 received 10, 20, 40 mg / kg of PAPP respectivelyafter a half an hour were influenced by gamma-ray (2greys).All injections continued for 3 days.All groups were bled to measure their testosterone, FHS and LH hormones.Statistical analysis carried out by SPSS 19 software. Results: The findings show that in the groups treated by gamma-ray, the amount of testosterone, FHS and LH hormones were reduced significantly compared with control group (P≤ 0.05). In the groups treated by para-amino Propiophenone (PAPP) and gamma-ray (from low to high concentrations), the level of testosterone, FHS and LH hormones increased gradually so that in maximum level, the hormone level reached to control level. Conclusion: PAPP reduced the damages caused by gamma-ray on the amount of testosterone, FHS and LH hormones. Its protective effect is dosage-dependent. It seems that PAPP protects cells and tissues from destructive effects of free radicals caused by gamma-rays, through hypoxia.}, Keywords = { gamma-ray, para-aminopropinophenone, testosterone, FHS, LH}, volume = {21}, Number = {2}, pages = {114-122}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-548-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-548-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Bazyar, F and Banitalebi, E and Amirhosseini, SE}, title = {The Comparison of Two Methods of Exercise (intense interval training and concurrent resistance- endurance training) on Fasting Sugar, Insulin and Insulin Resistance in Women with Mellitus Diabetes}, abstract ={Background & aim: Exercise is an important component of health and an integral approach to the management of diabetes mellitus. The purpose of this study was to compare the effects of intense interval training and concurrent resistance- endurance training on fasting sugar, insulin and insulin resistance in women with mellitus diabetes.   Methods: Fifty-two overweight female diabetic type 2 patients (aged 45-60 years old with fasting blood glucose≥ 126 mg/dl) were selected to participate in the present study. Participants were assigned to intense interval training group (N=17), concurrent resistance- endurance training group (N=17) and control group (N=18). The exercises incorporated 10 weeks of concurrent resistance- endurance training and intense interval training. Fasting blood sugar, serum insulin concentrations levels were measured. Concurrent training group trained eight weeks, three times a week of endurance training at 60% of maximum heart rate (MHR) and two resistance training sessions per week with 70% of one repetition maximum (1-RM). Intense interval training group trained for eight weeks, three sessions per week for 4 to 10 repeats Wingate test on the ergometer 30s performed with maximum effort. The control group did no systematic exercise. At the end of experiment 42 subjects were succeed and completed the study period, and 10 subjects were removed due to illness and absence in the exercise sessions. Fasting blood sugar and insulin levels 24 hours before and 48 hours after the last training session was measured.   Results: The findings indicated that in periodic fasting, the blood sugar in intensive training group had a marked decrease (p= 0.000) however, the fasting blood sugar of exercise and power stamina groups reduced significantly (p=0.062). The results showed no significant difference between the groups (171/0 p =0.171). Fasting insulin (p <0.001) and insulin resistance (0001/0 = p=0.001) in periodic intensive training group were significantly reduced after the exercise program. The results between groups indicated a marked difference in fasting insulin (p=0.036) and insulin resistance (p=0.008) respectively.   Conclusions: Concurrent resistance- endurance training and the intensive training could have a positive effects on blood sugar levels, insulin and insulin resistance of women with diabetes mellitus.  }, Keywords = {intense interval training ,concurrent resistance, endurance training, fasting glucose, Mellitus Diabetes}, volume = {21}, Number = {2}, pages = {123-134}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1121-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1121-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {yaghobi, L and mirazi, N}, title = {The Effect of Hydro-alcoholic Extract of Hyperricum PerforatumL. on Some Blood Parameters in Male Rats Treated with Cyclophosphamide}, abstract ={Background & aim: Cyclophosphamide is an anti cancer drug which causes alkylation of DNA in cells. The side effects of cyclophosphamide are bone marrow damages and anemia. Hypericum perforatum is a medicinal plant which widely used in traditional medicine. In this study the hemotopoetic effect of Hypericum perforatum leaf extract (HPE) on bone marrow function and blood parameters in male rat were treated with cyclophosphamide was investigated. Methods: Forty two male Wistar rats with an average body weight of 220±25 gr were randomly divided into 6 groups (n=7): control group taking normal saline,0.5ml/day, i,p ),witness group taking cyclophosphamide (15mg/kg/day, i.p.), positive control group taking HPE (200mg/kg, i.p/day),  treated groups 1, 2 and 3 recieved cyclophosphamide ,(15mg/kg/day, i.p. + 100mg/Kg, 200mg/Kg and 400mg/kg  HPE /day for 10 days, i,p). At the end of study blood samples were collected from heart directly. RBC, WBC, Hct, Hb and PL were meseaured. Data are presented as mean ± standard deviation and were analyzed using ANOVA and Tukey tests. Results: The results indicated that cyclophosphamide caused damage on bone marrow, which in this case significantly reduced the number of blood cells and platelets in the group treated with cyclophosphamide (P<0.001). Blood parameters in the groups treated with HPE increased significantly compared with the group which received cyclophosphamide alone (P<0.001). Conclusion: The Hypericum perforatum hydoethanolic extract contains antioxidant and flavonoids compounds which could protect the bone marrow tissues against cyclophosphamide.     }, Keywords = {Hypericum perforatum, Blood parameters, Cyclophosphamide, Rat}, volume = {21}, Number = {2}, pages = {135-147}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-960-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-960-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Barazesh, F and Mirzaei, A and Abbasian, Z and GhavamiZadeh, M}, title = {The Effect of Hydroalcoholic Extract of Glycyrrhizaglabra L. (licorice) Root on Serum Level of Glucose, Triglyceride and Cholesterol in Polycystic Ovary Syndrome Induced by Letrozole in Rats}, abstract ={Background & aim: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder which effects 15.6 %  of women in Iran. Licorice (Glycyrrhizaglabra L.) has phytoestrogenic and anti-diabetic effects. The aim of this study was to investigate the effects of hydro-alcoholic Licorice root extract on blood sugar, triglycerides and cholesterol in the rats with PCOS. Methods: In the present experimental study, 50 female puber Sprague dawley (180±20 gr) rats with regular sexual cycle were entered in the study.  Studied groups included: first, the Normal group, receiving carrier (normal saline) (2 ml/kg) daily orally for 21 days. Then, the letrozole group which received letrozole (1 mg/kg) dissolved in normal saline (2 ml/kg) for 21 days and then normal saline (2 ml/kg) daily orally for 30 days. The last groups, Treatment groups 1 and 2, which received letrozole (1 mg/kg) dissolved in normal saline (2 ml/kg) for 21 days then hydroalcoholic extract of Licorice root (200 and 400 mg/kg) dissolved in normal saline (2 ml/kg) daily, orally for 30 days respectively. To conclude, blood samples were collected from the heart and also the serum level of blood sugar, triglyceride and cholesterol was measured. The data were analyzed using one-way ANOVA (p< 0.05). Results: The mean serum level of blood sugar increased in the Letrozole group compared to the normal group and decreased in the treatment groups compared to Letrozole group (p< 0.05). No statistically significant differences were seen in mean of serum level of triglyceride and cholesterol between all groups. Conclusion: The licoricecan extract improved the adverse side-effects caused by diabetese in polycystic ovary syndrome However, its effect on dyslipidemia in patients requiring further investigations.}, Keywords = { polycystic ovary syndrome, Glycyrrhizaglabra L., Blood sugar, Triglyceride, Cholesterol}, volume = {21}, Number = {2}, pages = {148-159}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1142-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1142-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Batol.mohamadtaghi@yahoo.com, B and HejaziDinan, P and ShamsipourDehkordi, P}, title = {The Effects of 12 Sessions of Mirror Therapy on Postural Control Kinetic Variables of Amputation below the Knee in Terms of the Manipulation of Afferent Information}, abstract ={Abstract Background & aim: Mirror therapy is a relatively new intervention which focuses on moving the defective part in front of the mirror. The intervention is proposed to be an important implement to improve stability during rehabilitation program of the amputee. The present study aimed to evaluate the effects of 12 sessions of mirror therapy on postural control kinetic variables of amputees when manipulating sensory information. Methods: In the present quasi-experimental study with pretest-posttest and random group design, 14 below knee amputees (n =7 control and n =7 experimental) were enrolled. The experimental group engaged in 12 session of exercise therapy in front of mirror, but the control group just did their daily routine activities without any intervention. To asses postural control, Computerized Dynamic Posturography was used which shows the balance score according to two variables of stability and displacement of the center of gravity while manipulating sensory organization in 6 conditions (absence or presence of vision, presence or manipulation of vestibular and kinesthetic information). For data analysis, multiple analysis of variance (MANOVA) with repeated measures and Bonferroni post-hoc test were used. Results: The results indicated that postural control improved in the experimental group compared to the control group in all six sensory manipulation conditions. The balance improvement in the mirror therapy group in the first condition (existence of three senses of vision, vestibular and kinesthetic) and second condition (elimination of sight and presence of vestibular and kinesthetic information) was higher than other circumstances. Balance scores were worse in condition 6 (manipulation of vestibular and kinesthetic) in the control group compared to other sensory conditions. Conclusion: Findings of the research revealed that 12 sessions of mirror therapy can improve balance in people with below knee amputations. Moreover, application of mirror in exercise sessions can reduce the amplitude of fluctuation and increase alignment and strategies, which helps promotion of balance control.}, Keywords = { Mirror Therapy, Kinetic Variable, Postural control, Amputee}, volume = {21}, Number = {2}, pages = {160-173}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1138-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1138-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Taghvaeinia, A}, title = {The Effectiveness of Forgiveness-based Group Intervention on Subjective Well-Being of the Wives of War Veterans}, abstract ={Abstract Background & aim: Psychological consequences of war, regardless of disruption in social functioning of the injured, bring about difficulties for the families of the injured and the larger society.  Promotion of subjective well-being is one of the objectives of modern-day psychology. The present study aimed to study the effectiveness of forgiveness-based group intervention in the subjective well-being of the wives of war veterans. Methods: The population of the present study included all the wives of war veterans in Noorabad Mamasani, Iran. In this interventional study, 40 participants selected through convenience sampling from the above-mentioned population were randomly assigned into two experimental and control groups. The instruments used in the study were Positive and Negative Affect Schedule (PANAS) and Satisfaction with Life Scale (SWLS) The research design was pre-experimental involving a pre-test and a post-test. Forgiveness-based group intervention was performed on the experimental group for 10 sessions, each lasting 90 minutes once a week. The control group received no instruction.  At the end of the treatment, a post-test was administered to both groups. ANCOVA was used for data analysis. Results: The findings revealed that forgiveness-based group intervention promotes the subjective well-being (increase in positive emotions and satisfaction with one’s life and decrease in negative emotions) in the intervention group, compared with the control group. In the pre-test administered to the experimental group, mean and standard deviation of positive emotions, life satisfaction, and negative emotions were 34.70 and 3.26, 15.80 and 3.20, 24.85 and 5.09, respectively. In the post-test given to the same group, mean and standard deviation of the above-mentioned variables were 41.60 and 2.52, 19.15 and 2.41, 16.70 and 2.59, respectively. Conclusion: The findings of the study suggest that it is possible to make use of forgiveness-based intervention to promote subjective well-being. Therefore, it could be said that forgiveness-based group intervention is effective in the subjective well-being of the wives of war veterans.  Subjective well-being, Forgiveness, Wives of war veterans}, Keywords = { Subjective well-being, Forgiveness, Wives of war veterans}, volume = {21}, Number = {2}, pages = {174-186}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1147-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1147-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Dizjani, F and Kharamin, Sh}, title = {Reality Therapy Effect on Marital Satisfaction and Women’s Quality of Life}, abstract ={Abstract Background & aim: Marriage means common life wedlock with relative independency protection. It could be one of the most complex human relationships.  Its stability could be strongly dependent on satisfaction and its quality. Using different psychological techniques and approaches, a lot of studies have been conducted to increase these marital indexes. Accordingly, the present study aimed to investigate the role of choice theory training to couple and its effects on marital life satisfaction and quality of marital life. The aim of this study was to evaluate the effect of reality therapy on marital satisfaction of married women employed at Yasuj University of Medical Sciences quality. Methods: The present study had a quasi-experimental design with pretest-posttest control group. The study population consisted of all employees married women of Yasuj university of Medical Sciences in 2014, which by random sampling 30 participants were selected and randomly assigned into two experimental groups for 2 months (8 sessions of 2 hours) of reality therapy training. Enrich marital satisfaction scale and Fletcher quality of marital life scale were used to collect the data. Data were analyzed using SPSS 23 and P value of 0.05. Results: The results indicated that the total mean scores in marital satisfaction in experimental groups (129.07±4.2) significantly increased compared to the control group (113.4±6.8). The mean differences   in all subscales (with except of leisure time and relative sub scales) were significantly different. In quality of marital life, mean scores were significantly different between two groups (120.32±5.3 in experimental group against 101.2±7.28 for control group). Conclusion: The results indicated that training of reality therapy based on choice theory to couples could increase marital satisfaction and quality of life.}, Keywords = {Marital life satisfaction, Quality of marital life, Choice theory, Reality therapy}, volume = {21}, Number = {2}, pages = {187-199}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1071-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1071-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Helalat, SH and Onsory, Kh and HajiMehdiNouri, Z}, title = {Frequency of *4 allele in CYP2D6 gene and its Association with Ovarian Cancer Risk in Tehran, Iran}, abstract ={Background & aim: CYP2D6 enzyme is one of the most important members of the cytochrome P450 superfamily which play an important role in the metabolism of many drugs. The CYP2D6 gene presents a high allele heterogeneity that significantly stimulated many changes between individuals in a population, so that classified into extensive, intermediate, or poor drug metabolizers. The CYP2D6*4 allele is the most common polymorphic allele of CYP2D6 gene which due to a nucleotide change of G→A )G1934→A(, resulting in a reduced or lack of activity of CYP iso-enzyme. The aim of this study was to evaluate the frequency of CYP2D6*4 allele among patient and control groups and to find out the relationship of this polymorphism with the risk of ovarian cancer patients in Tehran. Methods: In the present case-control study, samples were collected in tubes containing EDTA. DNA is extracted from cancer tissue and blood controls group were performed. The frequency of CYP2D6*4 allele was determined among 120 patients who were admitted to Imam Khomeini Hospital by PCR-RFLP method and then compared with 125 normal controls who visited the same center. The collected data were analyzed using logistic regression analysis. Results: The results show that the prevalence of patients group with poor metabolism of drugs (PM) 13.3%, heterozygotes extensive metabolizer (HEM) 23.3% and extensive metabolizer (EM) was 63.3% respectively. The results indicated no significant association was seen between HEM and ovarian cancer risk (OR=1.27; CI 95% ; 2.85-0.56; P=0.55). Also no association was observed between PM and risk of this disease among the studied population (OR=0.75; CI 95%; 1.38-0.41; P= 0.36). Conclusion: There was no meaningful association between CYP2D6*4 allele which results in variations of G1934→A genetic polymorphism and ovarian cancer has been observed in the study population.}, Keywords = { CYP2D6*4 allele, Polymorphism, Ovarian cancer, PCR-RFLP}, volume = {21}, Number = {2}, pages = {200-211}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1036-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1036-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Shahmoradi, M and Khezri, S and AbtahiFroushani, SM}, title = {The Effects of Nicotine on the Stimulation of the Cholinergic System and Immune Responses Changes in Animal Models of Multiple Sclerosis}, abstract ={Background & aim: Lately, it has been demonstrated that the signaling by the α7 nicotinic receptors produces the anti-inflammatory condition in both macrophages and T cells. Moreover, activation of macrophages and T cells play an important role in multiple sclerosis (MS).  In the present study, the therapeutic effect of nicotine on experimental autoimmune encephalomyelitis (EAE), an animal model of MS, and its effects on T-helper cells responses was evaluated. Methods: In the present experimental study, EAE was induced by homogenised guinea pig spinal cord and complete Freund’s adjuvant in wistar rats. Animals were allocated in two therapeutic groups (n=7 per group). Treatment with nicotine (2.5 mg/kg-daily) was started in treatment group when the treatment group developed a disability score (at day 12). At the same time, the control group received only the solvent with the same program. Signs of disease were recorded daily until the day 36 when animals were sacrificed. The Splenocytes were checked for proliferation by MTT test and cytokine production by ELISA. The level of nitric oxide in serum was checked by griess test. The data was analyzed using the Student t test and Mann-Whitney U. Results: Nicotine administration in the treatment group significantly reduced the clinical symptoms after the onset of symptoms. Simultaneously with the decrease of the level of serum nitric oxide, nicotine significantly decreased the pro-inflammatory cytokine IL-17 and IFN-γ. The levels of anti-inflammatory IL-10 were not changed significantly. Lymphocyte proliferation was significantly decreased in treatment group compared to control group Conclusion: The results of this study indicated that nicotine had immune modulatory effects and could be used to control MS disease.}, Keywords = { Multiple sclerosis, Experimental autoimmune encephalomyelitis, Nicotine, lymphocyte response}, volume = {21}, Number = {3}, pages = {212-224}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1214-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1214-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Ghayedi, N and Khoshnam, SE and Bahaoddini, A}, title = {The effect of Hydro-alcoholic Extract of Licorice (Glycyrrhiza Glabra) Rhizome on the Mechanical Activity of the Colon of Male Rats and its Interaction with Adrenergic System}, abstract ={Abstract: Back ground & aim: Glycyrrhiza glabra (Licorice) is a native medicinal plant of Iran which its rhizome has been traditionally used for treatment of bowel spasm and diarrhea. Accordingly, the present study aimed to determine the effect of the hydro-alcoholic extract of licorice rhizome on mechanical activity of isolated colon of male rats. Methods: In the present experimental study, the colon tissue of 10 adult male rats were dissected and divided into two groups: experimental and control. Each group consisted of 10 strips of tissue. Then, the mechanical activity of tissue strips were recorded by power lab A-D instrument in basal condition, and after administration of phenylephrine and epinephrine and propranolol in the presence and absence of licorice rhizome extract (with effective dose 0.036 mg/ml). Moreover, the mechanical activity of control group strips were recorded at the same condition with extract solvent (ethanol %70). Data were analyzed statistically with using the SPSS software version 19 using Independent-Samples t-test. Result: The mechanical activity of tissue in presence of extract and epinephrine significantly decreased (p≤0.05) compared to the control group. While the mechanical activity in the presence of extract and propranolol significantly increased (p≤0.05) compared to the control group. However, no significant modification was observed in the mechanical activity of the tissue  in the presence of phenylephrine and extract compared to the control group.  Conclusion: According to the present study, it could be concluded that hydro-alcoholic extract of licorice maybe has modifying effect on colon motility via synergist effect with beta adrenergic receptors and independent of the alpha adrenergic receptors.}, Keywords = { Licorice, Mechanical activity, colon, Adrenergic}, volume = {21}, Number = {3}, pages = {225-237}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1252-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1252-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {zar, A and Hoseini‎, SA ‎ and Amirhosseini‎, SE and Siavashi, N‎}, title = {The effects of eight weeks of endurance training on BDNF, insulin and insulin resistance in rats}, abstract ={Background & aim: Brain-derived neurotrophic factor (BDNF) is one of the most important neurotrophin that it will lead to the development of metabolic syndrome. Brain-derived neurotrophic factor directly related to conditions such as epilepsy, Alzheimer's and depression. The purpose of this research was investigate effect of eight weeks endurance training on Neutrophic factor that derived from the rats' brain , Insulin and resistance to Insulin. Methods:  Statistical Society in this research consist of Male Sprague Dawley rats. Among them, 24 rats at 8 weeks of age and weight of 43/31 ± 72/280 grams were purchased from Pasteur Institute in Shiraz. Then transferred to the laboratory and randomly assigned to two experimental and control groups (endurance training). Also before the start of the study, the rats a period of one week to adapt to the new environment and the activities during the treadmill. During eight weeks the endurance exercise mice group running on treadmill machine without slope(zero percent slope) with speeding 8 till 20 meter per minute and about 60 minute in each session and 3 session in a week. Control mice group during this time did not have any exercise activity. 24 hours after the last training session at the end of week the eighth, the rats sacrificed to measure the parameters studied until biochemical alterations resulting endurance investigate training effects. For analysis data, was used of independent T-test that was considered as significance level (a=0/05). Results: Analysis of the findings showed that Eight weeks of endurance training has not   significant effect on the Brain-derived neurotrophic factor in rat(p=0/011). Eight weeks endurance training leads to a significant reduction on Insulin (p=0/005) and eight weeks endurance training leads to significant reduction resistance to Insulin (p=0/001).  Discussion: Hence get conclusion that endurance training have significant effect on reduction of Insulin and don't have any effect on Neutrophic factor that derived from brain.}, Keywords = {insulin, exercise, Lithium Chloride, Brain-Derived Neurotrophic Factor, Rats}, volume = {21}, Number = {3}, pages = {238-248}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1253-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1253-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Kazemi, N and Kordi, MR and Noori, R and Kasraian, M}, title = {The Effect of Aerobic and Resistance Training Program on Fasting Blood Sugar Levels and Insulin in Women with Gestational Diabetes}, abstract ={Background & aim: Gestational diabetes is defined as diagnosing impaired glucose tolerance for the first time during pregnancy. The purpose of the present study was to compare the effect of aerobic and resistance training on fasting blood sugar, insulin and insulin resistance in women with gestational diabetes. Methods: A total of 34 women with gestational diabetes voluntarily participated in the present Semi- experimental interventional study, which were selected from the available sampling pool. The participants were randomly assigned into 3 groups. 12 participants (age 28/92 ± 3/60 years) participated in an aerobic training group (3 days/week, 30-45 min/day, 50-70%maximum heart rate), 11 participants (age 30/27 ± 4/14 years) participated in a resistance training group (3 days/week, 2-3 set of 15 repetition, 50-70%maximum heart rate and Rating of perceived exertion), and 11 participants (age 29/18 ± 4/23 years)  were in control group who did not participate in any exercise program during the study period. Blood samples were collected in the pre-test and post-test to assess the level of blood sugar and insulin. Statistical analysis of covariance was used to compare the groups. The data were analyzed by the SPSS software (ver.23. The significant level was considered p≤0.05. Results: The results of the present study showed a significant difference in insulin plasma levels  (p = 0.031), insulin resistance index (p = 0.008) and insulin sensitivity among groups. T-test results indicated a significant reduction in fasting blood sugar of resistance group (p=0.12) but no increase was observed in the aerobic group. At the levels of insulin, insulin resistance and insulin sensitivity, no significant changes were observed in exercise group. Conclusion: It was concluded that resistance training compared with aerobic training was more effective in reducing fasting glucose levels in women with gestational diabetes.  fasting blood sugar, insulin, insulin resistance, insulin sensitivity, pregnancy}, Keywords = { fasting blood sugar, insulin, insulin resistance, insulin sensitivity, pregnancy}, volume = {21}, Number = {3}, pages = {249-264}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1212-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1212-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Mogharnasi, M and Baya, J and Foadoddini, M and Salehikia, A and ,Hosseini, M and ShahamatNashtifani, F}, title = {The Effect of Colostrum along with Aerobic and Anaerobic Exercise on Lipid Peroxidation and Total Antioxidant Capacity of Male Wistar Rats}, abstract ={Background & aim: The consumption of food supplements in order to eliminate oxidative damages induced by exercise are common among athletes. Previous studies have shown that bovine colostrum has antioxidant properties, but no study has ever been done to evaluate its effectiveness on Oxidative stress and antioxidant capacity. The aim of study was to investigate the effects of bovine colostrum along with aerobic and anaerobic exercise on Lipid peroxidation and antioxidant capacity in male Wistar rats.   Methods: In the present experimental study, 48 male Wistar rats were randomly divided into six groups (control, colostrum supplement, aerobic exercise, anaerobic exercise, colostrum supplements and aerobic exercise, colostrum supplements and anaerobic exercise). Colostrum group received daily for ten weeks dosing 300 mg /kg bovine colostrum powder orally. Exercising groups worked out three times a week for a period of 10 weeks on a custom-made treadmill for rodents. Blood samples were taken before and 24 hours after the last exercise session on an empty stomach. Data were analyzed using Kolmogorov-Smirnov tests, One Way ANOVA and post hoc Tukey at α<0.05.   Results: The plasma levels of oxidative stress index (MDA) in all groups except colostrum supplement and anaerobic exercise compared with the control group was significantly reduced (p<0.05). The antioxidant capacity in all groups except anaerobic exercise group compared with the control group was significant increased (p<0.05).   Conclusions: The results indicated that colostrum supplementation with ten weeks of aerobic exercise had better effect on the control of oxidative stress and antioxidant capacity compared to anaerobic exercise.    }, Keywords = {Bovine Colostrum, Aerobic Exercise, Anaerobic Exercise, Oxidative Stress, Antioxidant Capacity}, volume = {21}, Number = {3}, pages = {265-277}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1200-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1200-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Arshi, A and Ansari, H and GhahramaniSeno, MM and Doosti, A and Khoramian, M and Sazgar, H}, title = {Comparison of GAS5 Long non-coding RNA Expression and NEAT1 in Breast Cancer Patients and Healthy People}, abstract ={Background & aim: Breast cancer entails 10% of all cancers in the world.  Among all types of cancers, 30 percent of women are infected with breast cancer. Non-coding of long RNA (lncRNA) is a new group of known genes in the human genome transcribed from large parts of the genome of eukaryotes and play an important role in the regulation of different biological processes. The aim of the present study was to compare the expression level of GAS5 lncRNA and NEAT1  in normal and neoplastic samples from breast cancer patients by RT-qPCR. Methods: In the present case-control study, 40 samples from patients with breast cancer tumor and 40 patients from non-tumor under the direct supervision of a pathologist specialist due to clinical presentation and laboratory findings were collected. After extracting DNA from normal and tumor tissues, cDNA synthesis method according to the protocol and RT-qPCR was performed by SYBR®Premix Ex TaqTM II kit.  LncRNA expression levels of genes GAS5 and NEAT1 was calculated using ΔΔCT. Data were analyzed using t-test. Results: The results of Real Time Reverse transcription-PCR indicated that partial expression levels of GAS5 lncRNA gene in tumor samples compared to normal GAS5 lncRNA of the gene, decreasing the expression, and the mean relative expression levels of lncRNA and NEAT1 gene in tumor samples compared to normal was overexpressed. These variation gene expression of LncRNA related to GAS5 about 1.5 times and 2 times to  lncRNA from  NEAT1 gene was observed respectively. Conclusion: Due to the previous reports, these lncRNAs act as tumor suppressor in breast cancer and had differential expression in tumor and normal tissues, which could be used as biomarker for cancer diagnosis. Moreover, expression of these lncRNAs in different breast cancer subtypes and patient with other blood raises the importance of this molecules as a biomarker for cancer diagnosis and prognosis.}, Keywords = { Breast cancer, LncRNA, GAS5, NEAT1, RT-qPCR}, volume = {21}, Number = {3}, pages = {278-289}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1162-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1162-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {AskariShahed, S and KarimzadehShirazi, K and Mousavizadeh, SA}, title = {Processing and Testing the Quality of Life in Families with Mentally Retarded Children}, abstract ={Background & aim: Mentally retarded children need more care on quality of life, therefore the family plays an important role, but the results indicate low levels of quality of life for these children and their families. The present study aimed to measure the quality of life in mothers of educable mentally retarded daughter motivated provide a model to measure quality of life and understanding of issues affecting the design. An attempt to investigate and describe the factors affecting the quality of family life with a disability and the relationship between these indicators and how to measure them families with children with mental retardation.   Methods: The research method was descriptive-analytic. The sample consisted of 75 mothers with a mentally retarded daughter who were participated in this study through census sampling. By studying literature, the related texts criteria of quality of life were extracted. All study information of participants was obtained by standard questionnaires. Using correlation analysis techniques, univariate regression, logistic regression analysis were analyzed through structural equations.   Results: The results indicated that the performance of family (family interactions, parenting, mental health and physical) capabilities mother (resilience and aggression), personal beliefs and quality of life of families with disabled children influenced it. Personal beliefs are an important determinant of quality of life.   Conclusion: The results of structural equation modeling and corresponding indexes indicated that the proposed model based on experimental data fitting was good and desirable product was in compliance with the conceptual model.    }, Keywords = { quality of life, mentally retarded, family performance, resilience, aggression}, volume = {21}, Number = {3}, pages = {290-304}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1168-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1168-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Moridikia, F and Khosrovani, SAM and Ghaedi, M and Zoladl, M and Moridikia, A and Mohseni, R and Alamdari, AK and Sharifi, A}, title = {Antimicrobial effect of hydroalcoholic extract of saturega multica and zinc oxide namoparticle on coagulase gene expression on clinical and standard samples of MRSA (Methicilin resistant staph aureus)}, abstract ={Background & aim: Methicillin-resistant Staphylococcus aureus (MRSA) as nosocomial pathogens have been causing severe and deadly diseases around the world.  Coagulase is an important virulence factor for this bacterium and exisist in all staphylococcus aureus isolates. In recent years, studies carried out into the effects of medicinal plants, nanoparticles against bacteria and pathogenic bacteria’s expression genes. The aim of this study was to investigate the antimicrobial effect of satureja mutica hydroalcoholic extract, zinc oxide nanoparticle, and zinc complex on the coagulase gene expression in clinical and standard isolates of methicillin-resistant staphylococcus aureus (MRSA) Methods: In the present quasi-experimental study, using micro dilution and MTT, the minimum inhibitory concentration (MIC) of hydro-alcoholic extracts of satureja mutica and zinc oxide nanoparticles were tested against MRSA strains. By polymerase chain reaction ((RT- PCR) coa gene expression in satureja mutica extract and zinc oxide nanoparticles treated were qualitatively evaluated. Data were analyzed using statistical tests Results: The MIC of hydro alcoholic extract of Satureja mutica  for standard strains and clinical S. aureus  were 3000 and 1500 µg/ml respectively, whereas, the MIC  of nanoparticle zinc oxide on Standards and clinical isolates  were 40 and 20 µg/ml.The hydro alcoholic extract of Satureja mutica on MIC concentration has significant inhibitory effect on coagulase gene expression but no effect was seen for clinical and standard MRSA. Conclusion: The results show a decline in the coa gene expression in vitro by RT- PCR method using satureja mutica  , but no effect on gene expression Housekeeping arc C. An inhibitory effect was observed on bacterial growth by zinc oxide nanoparticles, but no inhibitory effect on gene expression was seen.}, Keywords = { MRSA, CuO, Cu complex, coagulase, Satureja Mutica}, volume = {21}, Number = {3}, pages = {305-313}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1167-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1167-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Paymard, A and Jawadi, M and Sadegh, R and Oshvandi, KH and Zarei, Z and Mirzaee, S and Saidinejad, Z and BehnamMoghaddam, M and Khalili, A}, title = {Chediak-Higashi: a case report}, abstract ={Background & aim: Chédiak–Higashi syndrome, a rare autosomal recessive disorder characterized by immune deficiency, bleeding diathesis, recurrent bacterial infections, albinism dynamic and progressive neurological disorder, as well as major organs such as the liver and spleen lymphocytic infiltration is determined. The aim of this study was to report a case of a rare manifestation of the disease. Case Report: The case-study in the present report was a 4-month-old female that two months after vaccination had intermittent fever associated with fever, weakness, which lasted more than a week. After blood tests, ultrasound and examination of blood cells, Chédiak–Higashi syndrome diagnosis was made. In terms of blood cells, pancytopenia, platelets and fresh frozen plasma were administered to the patient to prevent bleeding. After Buttock infections, the patient was suffering from septicemia and septic shock followed by a lack of response to resuscitation and cardiopulmonary arrest and then died. Conclusion: In this patient all Chediak Higashi syndrome, including long fever, loss of appetite, frequent infections, albinism variable and multiple neurological deficit was seen. Chdyak Higashi syndrome is treatable with early diagnosis and bone marrow transplantation.}, Keywords = {Chediak higashi syndrome, blood disorders, prolonged fever}, volume = {21}, Number = {3}, pages = {314-320}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1166-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1166-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Ghorbanian, B and Saberi, Y}, title = {The Effects of Eight Weeks of Progressive Resistance Training on Eotaxin Serum Levels in Overweight and Obese Men}, abstract ={Background & aim: Eotaxin, a pro-inflammatory adipokine is secreted from adipose tissue, which its secretion increases in the obese, plays a key role in the pathogenesis of asthma. The aim of this study was to investigate the effects of eight weeks’ progressive resistance training on serum eotaxin, non-HDL-c, insulin resistance and some physiological variables in overweight and obese men. Methods: In the present quasi-experimental study, 20 healthy overweight and obese male (22.75±1.29 yr, 89.22±13.08 kg, 28.36 ±3.98 kg/m²) were participaped and randomly assigned into training (n =10) and control (n =10) groups. Progressive resistance training was carried out for eight weeks (4 d/wk, 60 min/d). Blood samples were taken before, and 48 hours after the last training session to evaluate serum variables. Eotaxin serum concentration were measured by sandwich ELISA method using a special kit manufacturing by Germany ZellBio Company. Dependent and independent t-test and Pearson correlation was employed for data analysis. The criterion of statistical significance was p<0.05. Results: Independent t-test results indicated no significant changes of the eotaxin serum concentration were seen in the progressive resistance training of the experimental group compared with the control group after eight weeks (p=0.65). On the other hand, the amounts of non-HDL-c (p=0.024), triglyceride (p=0.017) and total cholesterol (p=0.032) significantly decreased. However,  modifications in other variables, such as insulin resistance index, body weight, body fat percentage, body mass index, waist to hip ratio and maximum oxygen consumption were not significant (p>0.05). The results of dependent t-test showed that after eight weeks of progressive resistance training,   changes  of all the variables in the experimental group (except LDL, HDL and insulin) were significant (p<0.05). Finally, in basic terms, the correlation between eotaxin with other variables (other than non-HDL-c) was not statistically significant (p<0.05). Conclusion: It seems that eight weeks of progressive resistance training can not have a significant effect on eotaxin serum and insulin resistance. However, it caused significant decrease in non-high-density lipoprotein, triglycerides and cholesterol as cardiovascular risk factors. Perhaps due to the intensity and high volume of this work, further study is suggested.  }, Keywords = {Progressive resistance training, Eotaxin, Overweight and obese men}, volume = {21}, Number = {4}, pages = {321-334}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1419-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1419-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Bakhtiyari, E and Yousofvand, N and Hatami, K}, title = {The Effects of Ethanolic Extract of Dill (Anethum graveolens)) on Morphine Withdrawal Symptoms in Addicted Male NMRI Rats}, abstract ={Background & aim: Medicinal herbs with natural materials can be effective and have fewer side effects than drugs with chemical composition in reducing withdrawal symptoms and are more effective in treating addiction. In recent years, anti-inflammatory, analgesic and anti-anxiety effects of Dill has been reported. The purpose of this study was to determine the effect of Dill ethanol extract on some withdrawal syndrome behaviors such as jumping, standing, climbing in male mice addicted to morphine. Methods: The present experimental study was conducted on 21 male NMRI mice with weighting 25 to 30 gr. Animals were divided into three groups: Group 1 received saline + naloxone (SN),  group 2 received morphine + saline + naloxone (MSN) and the third group received   morphine + ethanol extract of dill (500 mg kg ip) + naloxone (MDN) respectively. Simultaneous with the injection of morphine, the dill extract was injected at the same time. In order to induce the development of morphine dependence, the mice received increasing doses of morphine (10, 20, 30, and 40 mg) during four days for ten times, respectively. To induce the withdrawal symptom, two hours after the last injection of morphine, naloxone at a dose of 5 mg kg was injected intraperitoneally. Two hours after the last injection of morphine, naloxone at a dose of 5 mg/kg was injected intraperitoneally. Jumping, standing on both feet and climbing the walls were counted during 30 minutes. The data were analyzed using the software Graph Pad prism. Results: The results showed that the ethanol extract of plant significantly reduces the number of jumping due to naloxone injection in the addicted rats (p <0.001), but in the rearing behaviors and climb the walls of the container, a significant difference was observed with morphine. Conclusions: The findings suggested that the Dill Ethanolic extract can decrease the jumping number due to Naloxone-induced effect.  Therefore, Dill Ethanolic extract may have an impact in reducing of withdrawal induction by morphine.}, Keywords = { Withdrawal, Dill Ethanolic extract, Morphine, Naloxone.}, volume = {21}, Number = {4}, pages = {335-347}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1421-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1421-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Ahmadzadeh-Notarki, Z and Emadi-Baygi, M and Peymani, M and Shayesteh, A}, title = {Comparison of TBX3 Gene Expression among Patients with Squamous Esophageal Cancer and Normal Individuals}, abstract ={Background & aim: Esophageal cancer is the eighth most prevalent cancer worldwide and the second in Iran. Annually, esophageal cancer makes up 3.2% of all new cancer cases. Altered expression of stem cells self-renewal genes is of great importance in the tumorigenesis. The aim of this study was to compare the TBX3 gene expression in tumoral samples of patients with squamous esophageal cancer and normal tissue samples of healthy individuals.   Methods: The present cross-sectional study was performed on 40 samples, including 20 samples of tumor esophageal cancer tissue and 20 samples of normal tissue samples from Imam Khomeini Hospital in Ahwaz, Iran. After extracting RNA from FFPE tissues and synthesizing cDNA, expression levels of TBX3 and GUSB (as internal control) genes were relatively quantified using qRT-PCR. Data were analyzed using t-test.   Results: The results of the qRT-PCR analyses showed that the average relative gene expression in tumor samples was higher than normal samples. Furthermore, TBX3 gene expression exhibited greater expression in the tumor samples of the patients in the 26-50 years age range in compared with the 51-81 years age range   Conclusion: According to the cancer stem cell theory, many tumors originated from stem cells leading to the inhibition of apoptosis and resistance to chemotherapy. Considering the role of TBX3 gene in self-renewal of stem cells and its increased expression in patients with squamous esophageal cancer, it seems that TBX3 gene might be used as a biomarker in the diagnosis and prognosis of esophageal cancer in future.    }, Keywords = {Squamous esophageal cancer, gene expression, TBX3, self-renewal}, volume = {21}, Number = {4}, pages = {348-359}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1420-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1420-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Barikbin, M and Peymani, A and Pourzereshki, N}, title = {Relative Frequency of Hemolysin and Cytotoxic Necrotizing Virulence Factors in Escherichia coli Isolated From Educational Hospitals of Qazvin, in 2012-2013}, abstract ={Background & aim: Urinary tract infections are the most common type of nosocomial infection. Escherichia coli (E. coli) is the most common cause of urinary tract infections (UTIs) in the community and in clinics. The treatment of these infections is often difficult due to several virulence factors and drug resistance. Adhesions, enzymes and toxins are important virulence factors which promote colonization and pathogenicity of this organism. In the present study, frequency of hemolysin and cytotoxic necrotizing factor-encoding genes and antimicrobial susceptibility were evaluated in E. coli isolates collected from urine samples in the educational hospitals of Qazvin, Iran.   Methods: The present cross-sectional study was conducted during 2012-2013. Urine samples were collected from patients with urinary tract infection from different wards of Qazvin teaching hospitals. All of the isolates were identified using standard biochemical and microbiology tests. Antimicrobial susceptibility was further evaluated by Kirby-Baure method according to Clinical and Laboratory Standards Institute guideline. For the presence of genes HLY and CNF, specific primers was used and then using polymerase chain reaction the strains were analyzed and sequenced. Data were analyzed using statistical tests.   Results: Altogether, 49 (38.9%) isolates showed the multidrug resistant pattern in which the highest susceptibility rate was shown to amikacin (91.3%) and imipenem (88.9%) and the resistance rate was reported against cefotaxime (83.3%) and ceftazidime (73%), respectively. PCR assay showed that 40 (31.7%) and 24 isolates (19%) were positive for the presence of hly and cnf genes, respectively. Hly and cnf-positive isolates were mostly obtained from patients admitted in internal medicine wards.   Conclusion: The findings of this study indicated multidrug resistant isolates and a considerable rate of hemolysin and cytotoxic necrotizing virulence factors in E.coli collected from urine specimens in hospitalized patients in Qazvin, emphasizing the importance of these virulence factors in infection prevention and control strategies.    }, Keywords = {Escherichia coli, Hemolysin, Cytotoxic necrotizing factor, PCR}, volume = {21}, Number = {4}, pages = {360-371}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1415-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1415-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Hosseini, E and Hosseini, SY and Hashempour, T and Fattahi, MR and Sadeghizadeh, M}, title = {Design Methods of Cell Adhesion Proteins Based on ELISA Usable in-vitro in Gene Therapy}, abstract ={Background & aim: One of the strategies to improve the therapeutic gene is targeting gene therapy. A method which can be considered, is adding code sequences peptide or protein with high tendency to target cells and secreting the therapeutic gene encodes a protein. However, evaluating the effectiveness of such changes in the targeted cell binding protein gene product with the usual therapeutic methods produced in prokaryotic system is directly impossible. The purpose of this study was to evaluate the design methods of cell adhesion proteins based on ELISA usable in-vitro in gene therapy. Methods: In order to target the therapeutic gene Mda-7 by using genetic engineering, peptide coding sequence RGD4C with the tendency to cancerous cell surface integrin were inserted shortly after the artificial signal peptide sequence and the N-terminal coding region of the protein. Then, the modified and unmodified cDNA eukaryotic expression vector pCDNA3.1 were matched. Vectors were transfected in HEK-293 cell line. Then Mda-7 secreted expression levels were measured in cell culture by ELISA. After adjusting the protein concentration of Mda-7 and RGD.Mda-7, in cells transfected media, they were used as a source of protein. Reduce the concentration of these genes was assessed two hours after exposure to the integrin cell lines with HepG2, M21 and lacking integrin Saos-2  were also determined by ELISA. The present study was conducted three times independently.  Data were analyzed using t-test. Results: Statistical analysis of the results suggested that the gene product of the gene product RGD.Mda-7 and Mda-7 to connect to HepG2 cells and M21 were more likely to have integrin. While binding to the cell lines of Saos-2, no significant difference were observed. Conclusions: It seems the present ELISA based method was a suitable strategy for cell attachment assay in gene therapy research.}, Keywords = {Cell adhesion assays, ELISA, RGD.Mda-7 , RGD}, volume = {21}, Number = {4}, pages = {372-381}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1416-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1416-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Bayrami, M and Movahedi, Y and Sepahvand, R and Mahammadzadegan, R and GasemBaklu, Y and Vakilee, S}, title = {Comparison of Executive Function and Difficulties in Emotion Regulation in Addicted with Upper and Lower Borderline Personality Traits}, abstract ={Background & aim: Borderline Personality Disorder is one of the most important health problems of people with undesirable consequences on family councils. The aim of the present study was to compare the executive function and difficulties in emotion regulation in addicted with upper and lower borderline personality traits. Methods: The present causal-comparative study included all male drug abusers who had been referred to addiction treatment centers. 80 addicts were selected by accessible sampling method and using a borderline personality traits (STB). Then, they were divided into two groups of 40 people for drug addicts in high and low. Using The Wisconsin Card Sorting Test and the scale of difficulty in the emotional regulation was conducted on two groups. Statistical data using multivariate analysis of variance MANOVA and LSD test were analyzed.   Results: The results indicated that compared to drug addicts with high borderline traits, the ones with low borderline traits had lower performance in Wisconsin Card Sorting Test  and the number of perseveration errors (p = 0.018) and total error (p = 0.002) was higher. Moreover, addicts with high borderline traits varied significantly higher scores in difficulty in emotional regulation (p=0.002) of the drug with low borderline personality traits.   Conclusion: The results indicated that addicts with high borderline traits, had weaker performance in executive function and higher levels of difficulty with emotional regulation. This may be due to neurological effects of drug addiction on their performance which leads to poorer performance compared with drug people with low borderline traits.    }, Keywords = {executive functioning, difficulties in emotion regulation, borderline personality traits, addiction}, volume = {21}, Number = {4}, pages = {382-395}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1417-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1417-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Hajari, A and Shams, M and Afrooghi, S and FadaeiNobari, R and AbaspoorNajafabadi, R}, title = {Using the Precede-Proceed Model in Needs Assessment for the Prevention of Brucellosis in Rural Areas of Isfahan, Iran}, abstract ={Background & aim: Brucellosis is considered as a significant health threat worldwide. The disease has been reported in more than a half-million people each year in 100 countries, according to the World Health Organization. This study aimed to determine the predictive factors of a needs assessment and prioritization of interventions to prevent brucellosis using the Precede - Proceed Model in Isfahan rural areas in 2015.   Methods: The present cross-sectional study (needs assessment by Delphi method) was conducted on 402 people aged 15 years and older in 20 villages of 44 villages which were randomly selected in the rural Regions of Tiran and Karvan county of Isfahan Province. The data were collected through questionnaires and a Self-made checklist based on the Precede-Proceed Model which its content and face validity was approved by experts and pilot projects. Data collected by the survey techniques agreement using chi-square and t tests were analyzed by the use of SPSS version 18 software.   Results:This study indicated that the subjects' awareness of the possibility of transmission of brucellosis by skin, breathing contaminated dust, the use of personal protective devices at the time of contact with animals were not appropriate. Increasing the access to veterinary services and vaccination of livestock herders in rural areas and helping in creating storage areas for livestock backcountry villages and moving the livestock to rural areas outside was one of the demands of the population. The present study revealed that between knowledge, attitude and performance of the participants with their educational level was a significant association (p≤0.05). Also, there was a significant relationship between enabling factors, reinforcing factors and skill and practice in the prevention of brucellosis and having cattle(P≤0.05).   Conclusion: Needs assessment performance before implementation of any intervention in the prevention of brucellosis could help the researchers, planners and policy makers to assist the design and implementation of interventions as well as supplying educational materials situation and priorities of influential disease control and prevention considerations to be put into targeted action that will have more impact and also be more effective.  }, Keywords = { Precede - Proceed Model, brucellosis, Isfahan}, volume = {21}, Number = {4}, pages = {396-409}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1418-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1418-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Shafiee, M and Rashidfar, R and Borzoueisileh, S and Ghorbani, M and Vafapour, H and Rahimi, S}, title = {The Effect of Occupational Exposure on Blood Parameters of Radiology Staffs in Yasuj}, abstract ={Background & aim: Radiology staffs are exposed to low doses of the occupational ionizing radiation. The long term intermittent exposure to low radiation doses may damage cells and result in various adverse biological effects. The blood cells have been found to be the most radiosensitive cells to ionizing radiation. The aim of this study was to investigate the relationship between low dose of occupational exposure to ionizing radiations and hematological parameters, including red blood cells, white blood cells and platelet counts of the radiology staffs of Yasuj hospitals. Methods: In the present case-control study, seventeen radiology staffs (8 females and 9 males) and seventeen healthy non-radiation workers were participated. Occupational radiation histories were determined by film badge dosimeter recordings for each radiology staff. The hematological parameters of the participated in the study were recorded by means of cell counter sysmix machine. Statistical analysis was performed by SPSS 21. The statistical analyses were done by one-way analysis of variance (ANOVA), and Pearson’s correlation coefficient. Results: The values of total white blood cells and platelet count were significantly lower among radiology staffs compared to the control group, but no significant difference was found between their red blood cells. No significant correlation was observed between gender and work experience with blood parameters. The file badge records for all of the radiology staffs were under occupational dose limits. Conclusion: Platelet and white blood cells parameters were found to be sensitive to low dose occupational ionizing radiation for radiology staffs. We suggest that the radiology staffs should use their personal dosimeters while their hematopoietic system should be evaluated by blood cells count.}, Keywords = { Blood parameters, occupational exposure, Radiology staffs}, volume = {21}, Number = {4}, pages = {410-419}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1422-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1422-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Vazifeshenas-Darmiyan, KH and Hosseini, M and Rezaei, R and Ezi, S and Malekaneh, M}, title = {The Effects of Aqueous Extract of Wild Pistachio (Pistacia Atlantica) leaves on Diabetic Nephropathy in Rat}, abstract ={Background & aim: Due to increased public interest in the use of herbal medicine, their efficacy and safety evaluation have become important. In some studies, Pistacia atlantica leave (PAL) extract suggested as a hypoglycemic agent. However, there is no study about its effects on diabetic nephropathy. Therefore, the present work was conducted to evaluate the effects of aqueous extract of PAL on some biochemical and pathological aspects related to renal function in diabetic rats. Methods: In the present experimental study, 40 severe diabetes male Wistar rats (180-200 gr) with STZ and eight healthy rats at the same age were equally divided into 6 groups and followed for a period of thirty days as the oral treatment respectively. Diabetic groups I ,II and III received 100, 200 and 400 mg/kg of PAL extracts, diabetic group IV received 50 mg/kg Captopril and diabetic group  V and healthy group received saline 0.9% as control groups. Finally, fasting blood glucose (FBG), Urine volume and 24 h urine total protein (UTP), blood nitrogen urea (BUN) and plasma creatinine (Cr) were assessed biochemically and also qualitative renal histomorphological alterations were assessed pathologically. Data were analyzed using one-way ANOVA and Tukey post hoc test. Results: In diabetic control group the FBS (383.5 ± 118.33), BUN (27.17± 2.86), Cr (1.3 ± 0.45), Urine volume (24.66± 5.10) and UTP (25.67 ± 1.51) of groups 1-5 significantly increased in comparison whit normal control group (p<0.0001 each). In addition:  severe glomerolosclerosis, mesangial matrix expansion and tuft-capsule adhesion were observed in diabetic rats. Unlike captopril, which could significantly reduce the mean level of urea nitrogen (p <0.001; 12.5 ± 2.81), creatinine (p=0.034; 0.97±0.14) and protein (p=0.002: 13.66 ± 3.48) compared with diabetic controls the histology of the group was evaluate and confirmed its moderator effects, Conclusion: The results clearly demonstrate that PAL did not have any beneficial effects on diabetic nephropathy in rats.}, Keywords = {Pistacia atlantica, Captopril, Diabetic Nephropathy, Rat}, volume = {21}, Number = {5}, pages = {420-434}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1194-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1194-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Rashidipouya, S and Mohsenikouchesfehani, H and Angaji, SA}, title = {The Effect of Propiconazole and Protective Effects of Selenium Gene Expression Profile of Caspase 9 in the Testicular Tissue of Male Sprague Dawley (SD) Rats}, abstract ={Background & aim: Conazoles including imidazoles or triazoles are anti- fungal agents widely used to prevent fungal growth and their infections. Propiconazole placed in this group is a systemic fungicide used widely for detoxification of cereal seeds especially rice in Iran and other countries. This fungicide were designed to inhibit a specific cytochrome P450, CYP51 (lanosterol-14-α- demethylase), a critical step in the biosynthesis of ergosterol, a steroid required for the formation of the fungal cell wall. In the present experimental study, the effect of propiconazole on Caspase 9 gene expression profile as an initiator of apoptotic process and protective effect of selenium were investigated. Methods: Forty SD rats were divided into 10 groups of 4,  including : control , sham1 (solvent of propiconazole, distilled water), sham 2 (solvent of selenium, normal saline) and 1 group received 0.5 mg/kg selenium ,3 groups received propiconazole in doses of 10,50,75  mg/kg and 3 groups received propiconazole in doses of 10,50,75 mg/kg propiconazole with 0.5 mg/kg of selenium. Injections were intrapritoneal for two weeks in alternate days. Then, using RT-PCR and Total Lab program gene expression of caspase-9 testicular of all groups were studied. Data were analyzed using descriptive statistics. Results:  A significant increase of caspase 9 expression were observed among all experimental groups compared to control and sham groups. These findings indicated that 0.5 mg/kg selenium is not a suitable dose to create protection in this experimental study.  Conclusion: The significant increase in Caspase 9 gene expression profile observed in all experimental groups as compared to control suggests activation of apoptosis and inefficacy of selenium to protect the testis against induced damages.}, Keywords = {Apoptosis, CASP 9, Propiconazole, SD rat , Selenium}, volume = {21}, Number = {5}, pages = {435-445}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1316-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1316-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Askari, M and Nazari, H and Rahimizadeh, SH and Sadeghimansorkhani, H and Daneshpayeh, NA}, title = {The Effect of the Hydroalcoholic Extract of Dill ( Anethum graveolens( Seed on Lipid Profile in Diabetic Male Rats}, abstract ={Background & aim: Nowadays, Diabetes is prevalent in different societies, and hyperlipidemia is one of the important outcomes and effective in the development of complications from this disease. Therefore, finding a medication to reduce hyperlipidemia without an adverse effects on blood sugar levels has always been investigated. Some studies have been reported the beneficial effects of the aerial parts of Anethum graveolens on lipid levels in the clinical and animal models. As there is no study on the effect of dill seed extract on blood lipid levels in diabetic rats; the aim of this study was to evaluate the effect of the dill seed extract on lipid profile in diabetic rats. Methods: In this experimental study, 24 rats with a weight range of 200 to 250 g were randomly divided into three groups of eight, including normal group, diabetic group (received normal saline) and diabetic group (received seed extract to 100 mg /kg). To induce diabetes, the rats were received streptozocin (50 mg /kg,) intraperitoneally. The dill seed extract was given for four weeks and then the blood samples were collected to measure LDL, HDL and triglyceride. The differences between the control and treatment groups were tested by one-way analyses of variance (ANOVA) followed by the Tukey post-hoc test. Results: Induction of diabetes significantly increased the serum concentration of LDL and triglycerides compared with the control group (p=0.001), but no effect was seen on HDL levels. Dill Oral administration of seed extract-dose (100 mg/kg) animal serum concentration of LDL significantly reduced in comparison with diabetic group (p=0.001). The triglyceride serum levels was significantly reduced compared to diabetic group after 4 weeks administration of dill seed extract (p<0.001), but no effect was observed on HDL in comparison to diabetic group (p=0.54). Conclusion: The results showed that the dill seed extract was able to reduce the serum levels of LDL and triglyceride in the diabetic rats. So it seems that this extract can reduce cardiovascular complications of diabetes through reducing the blood lipid profile.}, Keywords = { LDL, HDL, triglycerides, diabetes, Dill seeds, Rats}, volume = {21}, Number = {5}, pages = {446-454}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1330-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1330-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Amirian, S and Amini, K and Parviz, M}, title = {Molecular Detection of Mycoplasma Pneumoniae Using P1 Gene in Patients With Chronic Obstructive Pulmonary Syndrome}, abstract ={Background & aim: Chronic obstructive pulmonary disease (COPD) is a chronic lung disease characterized by irreversible progressive obstruction of the airways which occur in three forms including; emphysema, chronic bronchitis, and small airways disease. Mycoplasma pneumoniae causes respiratory problems such as sore throat, pharyngitis, tracheobronchitis and other respiratory infections, especially in patients with COPD. Conventional methods for detection of M. pneumoniae have restrictions so that, the use of a reliable and sensitive method is essential. Therefore, the aim of this study was to identify Mycoplasma pneumoniae in respiratory secretions of patients with COPD by PCR method. Methods: In the present cross-sectional study, a total of 120 respiratory secretions samples were collected from patients with COPD during a one year duration (2014-2015).  Bacterial identification was performed by the PCR method and confirmed by DNA sequencing. Collected data were analyzed by cross-sectional analysis. Results: The most occurrence of Mycoplasma pneumoniae respiratory infections was in the age group of 4-21 years and the lowest rate was presented in the age group of 0 to 3 years. The results also indicated that of the collected 120 samples, 8 samples (6.6%) were positive for Mycoplasma pneumoniae and carried the P1 gene. These high rates of infection with these types of Mycoplasma were indicated in patients with chronic obstructive pulmonary syndrome. Conclusion: The results of the present study revealed that Mycoplasma pneumoniae can be one of the factors likely to develop COPD. The PCR method used with specific primers was able to detect Mycoplasma pneumoniae in respiratory secretions. This may facilitate the treatment portion of patients with symptoms of COPD.}, Keywords = {Mycoplasma pneumoniae, Multiplex PCR, Chronic Obstructive Pulmonary Syndrome.}, volume = {21}, Number = {5}, pages = {455-464}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1269-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1269-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Khalajinia, Z and NikbakhtNasrabadi, A and Behboodi-Moghadam, Z and Yadollahi, P and Abbasi, M}, title = {Returning to life, the Lived Experiences of Pregnancy in Women with HIV: A Phenomenological study}, abstract ={Background & aim: Pregnancy is every woman's stage of life. During this period, women experience physical, mental and social changes. It is very sensitive, challenging and therefore a critical period for every woman particularly in HIV-positive women. During pregnancy, an HIV-positive mother is facing a psychological crisis which includes fear of transmission to children, death, leaving children to the family or a guardian, adverse effects during pregnancy and the effects of pregnancy on their health. Therefore, HIV-positive pregnant women are vulnerable and require supportive interventions.  Care for pregnant women with HIV negative women are unique and different. However, no more information about experience of pregnancy in HIV positive women exists. Therfore, the aim of the present study was to explore the lived experience of pregnancy in HIV-positive women. Methods: The present qualitative study with hermeneutic phenomenological approach included 12 HIV-infected pregnant women who referred to the counseling center for behavioral diseases at Imam Khomeini Hospital of Tehran University of Medical Sciences who were recruited through purposive sampling. Data were collected through semi-structured interviews. Data saturation was achieved after 16 interviews, each 40 to 90 min of duration with participants and then was analyzed by the method proposed by Diekelmann (1989). Results: The participants in the present study were of 22- 39 years of age. After data analysis, the main themes and 3 sub-themes emerged. These themes included: “return to life” with the three sub-themes of experience of motherhood, stability and protection, and gratification. Conclusion: The results revealed that although the experience of pregnancy in HIV-positive women was associated with a deep sense of fear of transmission of the disease and having children was viewed as a way of hope. Motherhood gave their lives meaning and provided for them to return to life. Understanding and awareness of all those are necessary for health care providers.The findings of this study emphasize on the need to design and implement comprehensive prevention strategies and interventions tailored to have a good feeling of pregnancy in these women.}, Keywords = {Pregnancy, HIV-positive women, Phenomenology, Qualitative Study}, volume = {21}, Number = {5}, pages = {465-480}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1201-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1201-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Salehian, O and Soori, R and Ravasi, AA and Choobine, S}, title = {Comparison of Endurance Training and Overtraining on the Balance of Th1 / Th2 in Male Wistar Rats}, abstract ={Background & aim: The immune system is involved in numerous activities including inflammatory and anti-inflammatory activities. The activities associated with the production of Interferonγ and Interleukin-4. The present study investigated the effect of endurance training on the balance of these two cytokines pays more. Methods: In the present study, 30 rats were selected and divided into 3 groups of 10: control, endurance and overtraining exercise. Endurance training protocol and overtraining were done for 12 weeks. Endurance training was done with the speed of 10 m/min in first week and 23m/min in last week. Overtraining protocol was done with the speed of 15 m/min in first week and 25 m/min in last week. Speleenectomy was done after interval training protocol, and then Interleukin 4 (IL4) and Interferon γ (IFNγ) were evaluated by the Eliza method. One-way ANOVA and Tukey post hoc test was used for data analysis. Results: The results showed a significant increase in the amount of (IFNγ) and a decrease in the levels of IL4 in endurance training group (p=0.01). The results also exposed an increase in levels of IL4 and decrease IFNγ levels in overtraining group which was significant (p=0.01). Conclusion: It can be concluded that the response to endurance training the amount of IFNγ and in response to overtraining the level of IL-4 was increased.}, Keywords = { endurance training, overtraining, IFNγ, IL4}, volume = {21}, Number = {5}, pages = {481-491}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1347-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1347-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Bakhshizadeh, SH and Afrooz, GH A and Beh-pajooh, A and GhobariBonab, B and shokoohiYekta, M}, title = {The Effectiveness of Resiliency based on Islamic Spirituality Training on Mental Health and Spiritual Resiliency among Mothers of Slow Pace (Mentally Retarded) Children}, abstract ={Background & aim: Birth and presence of slow pace children in each family can be considered as challenging and adverse event that probably leads to stress and frustration and mental health related complications. According to several studies that show positive and significant relationship between resiliency and values and religious beliefs and their impact on mental health,the present study was conducted to evaluate the effectiveness of resiliency skills training based on Islamic spirituality in promoting mental health and spiritual resilience among mothers of Slow Pace children. Methods: The present study used a semi-experimental design with pre test-post test which was conducted among mothers of Slow Pace Children in Dehdasht, Iran, and the countryside using random sampling, in which 30 of these mothers were randomly divided into two experimental and control groups, participated in this study. Twelve sessions of resiliency training based on Islamic spirituality were held for experimental group of 15 people.The tools used in this study included a mental health questionnaire-28 (Ghq) and resiliency based on Islamic spirituality researcher made scale that were completed by individuals in pre and post tests. Finally, collected data were analyzed by multivariate analysis of covariance (MANCOVA). Results: Analysis of data using multivariate analysis of covariance showed that utilization of Intervention program among mothers of Slow Pace children in experimental group was significantly (P>0/05) effective on mental health and components of resiliency based on Islamic spirituality. In other words, spiritual resiliency skills training was led to improve depressive symptoms, social functioning and components of spiritual resiliency such as patience, contentment, Submission and thanksgiving. Conclusion: The results of the present study indicated that through changes in attitude of Slow Pace children's mothers, resiliency skills training based on Islamic spirituality can improve mental health and components of resilience-based on Islamic spirituality and helps them keep their mental health despite the exposure to chronic stress and tension.}, Keywords = { mothers of Slow Pace Children, Resiliency based on Islamic Sprituality Training, Mental Health.}, volume = {21}, Number = {5}, pages = {492-512}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1357-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1357-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {MoghadamAhmadi, A and Ranjbar, E and Irannezhad, M}, title = {A case Report of Human T-cell lymphotropic Virus Type 1(HTLV1) Infected Virus with Similar Multiple Sclerosis Symptoms in a Non-endemic Area}, abstract ={Background & aim: Human lymphotropic retrovirus type 1( HTLV1) is the first known virus which could cause serious diseases such as adult leukemia- lymphoma T-cell lymphoma (ATL) and Tropical Spastic (TSP). On the other hand, due to the HTLV1 similarity symptoms in patients with multiple sclerosis symptoms in Khorasan as the region's endemic, knowledge and understanding of the virus and the disease is necessary in other areas as well. The aim of the present case report study was to investigate the HTLV1 infected virus with similar multiple sclerosis symptoms in a Non-endemic area. Case presentation: The patient in the present case report study was a 56 years old women which her illness was early diagnosed as MS (multiple sclerosis).  No sign of improvement in therapy period was observed. Therefore, due to limited symptoms in lower extremities and sphincter dysfunction, her serum and cerebrospinal fluid for the presence of antibodies anti HTLV1 was evaluated. The presence of Abs with clinical symptoms, cause diagnosis of the virus in the patient. Conclusion: This patient was referred with symptoms of progressive paraparesis spatic and at first her disease was mistakenly diagnosed as MS.  Due to lack of response to treatment and atypical clinical symptoms related to MS and Khorasan province after two years the patient was diagnosis as HTLV1. It is recommended to apply differential diagnosis of MS in specific geographic regions, such infection  as HTLV1 especially in endemic areas should be considered.}, Keywords = {HTLV1, Multiple Sclerosis, Spastic Paresis}, volume = {21}, Number = {5}, pages = {513-520}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1169-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1169-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Abbasi, A and RahmaniKukia, N and ,AbtahiFroushani, SM}, title = {The Change in the Functions of Neutrophils after Being Stimulated with LPS-primed Mesenchymal Stem and Treated with Green Tea}, abstract ={Background & aim: Recently, the interaction of lipopolysaccharide activated by mesenchymal stem cells and neutrophils has been proven. The aim of the present study was to evaluate the effect(s) of the Green tea extract, as a widely consumed beverage on the interaction of lipopolysaccharide activated MSCs on neutrophils. Methods: In the present experimental study, after the isolation of mesenchymal stem cells from bone marrow of rats was conducted, these cells were stimulated with 10 ng/mL LPS for 1. Then, the supernatant was discarded and washed out to remove LPS cells.  Afterwards, the cells were incubated with different concentrations of green tea (10, 100 and 500 micrograms per ml) for 24 hours. Subsequently, the mesenchymal stem cells were co-cultured with neutrophils and incubated for other 4 h. Finally, the neutrophil function was evaluated. The data were analyzed by Kruskal wallis test. P values less than 0.05 were considered statistically significant. Results: Pro-inflammatory mesenchymal stem cells (Challenged with LPS) caused a decrease in vitality, Neutral Red-uptake and respiratory burst of activated neutrophils. Treatment of pro-inflammatory mesenchymal stem cells with higher concentration of green tea extract potentiated the decrease rate of Neutral Red-uptake and respiratory burst of activated neutrophils. Moreover, the vitality of neutrophils increased in a dose-independent manner by green tea extract.  Conclusion:It seemed that the treatment of mesenchymal stem cells in inflammatory condition with Green tea extract may potentiate the role of mesenchymal stem cells to increase phagocytosis and the respiratory burst of neutrophils cells.  }, Keywords = {Mesenchymal Stem Cell, Lipopolysaccharide, Neutrophil, Green tea extract}, volume = {21}, Number = {6}, pages = {521-535}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1394-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1394-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Farahmand, M and Tajali, M}, title = {The Effect of Salvia Rhytidea Extract on the Number of Cells of Different Layers of Cerebellar Cortex Following Ischemia Reperfusion in Rats}, abstract ={Background & aim: Salvia has anti-oxidant oxygen free radicals which are generated during the interruption and reestablishment of ischemia reperfusion.  The aim of study was to investigate the effect of Salvia Rhytidea extract on the number of cells of different layers of cerebellar cortex following ischemia reperfusion in rats. Methods: In the present experimental study, 35 adult male rats were randomly divided into 7 groups of 5: Group 1 (control-): Sampling without ischemia. Group 2 (control +): Cerebellar ischemia with administration of normal saline. Group 3(sham): Manipulation without ischemia with normal saline administration. Group 4   received (3.2 mg/kg) aqueous and alcoholic Salvia extract 2 hours after ischemia. Group 5 received 50 mg/kg silymarin drug, 2 hours after ischemia. Group 6 received 3.2 mg/kg aqueous and alcoholic Salvia extract 72, 48, 24 and 0 h before ischemia and group 7 received silymarin drug (50 mg/kg), 0, 24, 48, and 72, hrs. before ischemia. 24 hrs. following reperfusion, the rats were euthanized and samples of the cerebellum were obtained. By using routine histological technique, the sections were stained by H&E. The measurement of cell count in cerebellar cortex were accomplished. Data were evaluated with One-Way ANOVA and Tukey diagnostic tests. Results: A significant decrease was observed in the number of neural cells in granular layer in the non-treated ischemia group and in the groups which received Salvia extract and silymarin, two hours after the ischemia (p< 0.05). No significant decrease was observed in the number of cells of this layer in the groups which received salvia extract before ischemia. But regarding the cell number of molecular and purkinje layers in above groups, no significant difference was observed compared to the control group (P˃0.05). However, no significant differences was seen in the number of cells layers compared to the control group (P˃0.05). Conclusion: Finally, administration of salvia extract and silymarin after ischemia, did not have any effect on improving the number of neuronal cells in the granular layer. However, pretreatment with Salvia rhytidea extract similar to silymarin drug improved the cerebellar injuries following ischemia.}, Keywords = {Ischemic, Salvia rhytidea, Rats}, volume = {21}, Number = {6}, pages = {536-551}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1459-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1459-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Karimpour, F and Razavi, SH and NubarTkhruni, F}, title = {Investigation of Antibacterial Properties of Yeast Strains Isolated from Iranian Richal and Traditional Dairy Products in Armenia}, abstract ={Background & aim:The use of bio preservative or strains as sources are interesting for food bioprocessing technologist,   and is one of the latest methods to increase the shelf life of food by the health authorities . The present study aimed to investigate the antibacterial activity of supernatants of yeasts isolated from Richal as a traditional dairy product and fermented dairy products in Armenia. Methods: In the present experimental study, the purified supernatant of 77 strains of Armenian yeast products and 12 strains from Iranian Richal were isolated. The purified supernatant were tested against three strains as food spoilages bacteria includes: B. subtilis 17-89, B. Thuringensis17-89, S.typhimuium G-38 , on 3media in 2 condition as aerobic and anaerobic. The inhibition zone of the supernatant were measured   and reported as antibacterial activity. Data were analyzed using statistical tests. Result: A total of 89 strains of yeasts, three species of Rachel and 9 strains of Armenian products (13.5% percent) had demonstrated antibacterial activity. T86 strains of Armenian yeasts and FA1 (25) of Rachel had shown more ZOI and antibacterial activity on three media at both aerobic and anaerobic conditions. Comparing the mean of ZOI upon three corruption factors, Rachel strains were significantly different (p <0.05). The highest and lowest effect was observed on Bacillus subtilis effect and Salmonella typhimurium respectively. Conclusion: The results indicated that the yeast strains isolated in anaerobic and aerobic conditions on spoilage bacteria had antibacterial activity effect. Thus, it could be concluded that adding the yeast or its supernatant to food as a bio preservative, may introduce a operative product to the food industry.}, Keywords = { Supernatant, Preservative, Richal, Antibacterial, Armenia}, volume = {21}, Number = {6}, pages = {552-562}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1289-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1289-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Esfahbodi, A and Fathie, M and Moazami, M and MohammadRahimi, GH R}, title = {The Effect of Aerobic Training on the Level of Growth Hormone and 17-beta Estradiol Middle-aged Women with Breast Cancer}, abstract ={Background & aim: Breast cancer is the most common type of cancer and the most common cause of death in middle-aged women in developed countries.  The results have indicated that sedentariness and hormonal changes increase the risk of breast cancer. The aim of the present study was to evaluate the effect of eight weeks of aerobic training on levels of growth hormone and 17-beta estradiol middle-aged women with breast cancer. Methods: In the present semi-experimental study, 15 women with breast cancer with the mean age of 44.46±17.15 years, weight (70.53±5.18 kg) and body mass index (27.58±2.18 kg/m2) were selected through available sampling and considered as the experimental group. The exercise program was performed three sessions per week, and every session lasting 40-60 minutes with an intensity of 30%-60% heart rate reserve (HRR) for eight weeks. Growth hormone and beta 17 estradiol levels pre and post aerobic training, 12 hrs of fasting and with 24 hrs of severe Lack of physical activity was measured during of eight weeks. Data were analyzed by paired samples t-test at a significance levels of P<0.05. Results: The growth hormone levels did not change significantly after eight weeks of aerobic exercise (P=0.447), whereas 17-beta estradiol levels decreased significantly (P=0.000). Conclusion: It seemed that eight weeks of aerobic exercise could reduce one of the breast cancer markers (17-beta estradiol); so these training are recommended for the improving or prevention of breast cancer.}, Keywords = { Exercise, Growth Hormone, 17-Beta Estradiol, Women, Breast Cancer}, volume = {21}, Number = {6}, pages = {563-575}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1284-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1284-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {MoradiyaniGizehRod, SK and MirDrikvand, FA and HosseiniRamaghani, N and Mehrabi, M}, title = {The Effectiveness of Mindfulness-based Parenting Training on Anxiety, Depression and Aggression of Mothers with Children Suffering from Oppositional Defiant Disorder}, abstract ={Background & aim: Mothers with children suffering from Oppositional Defiant Disorder experience greater problems related to mental health including anxiety, depression and aggression. In this regard, the aim of the present study was to evaluate the effects of a mindfulness-based parenting training in anxiety, depression and aggression of mothers with children suffering from Oppositional Defiant Disorder.  Methods: The present semi-experimental study consisted of a pretest-posttest control group. The statistical population of the study included all mothers who had a female student with Oppositional defiant disorder (age group 6 to 12 years) of primary school in Nour Abad, Iran. Sampling was conducted in two stages, random and purposive. For this purpose, 34 mothers of girls with Oppositional defiant disorder after purposive sampling were randomly assigned to experimental and control groups (17 in each of groups). The Child Behavioral Checklist (CBCL) and Teacher Report Form (TRF) with clinical interviews were used for screening. Also, the anxiety and depression inventory and aggression questionnaire were used to collect data in two conditions (pretest and posttest). Mindful parenting course was implemented for the experimental group in 8 sessions, 2 hours each. Data were analyzed using SPSS software (ver. 23), descriptive statistical parameters (mean and SD) and univariate analysis of covariance (ANCOVA). Results: Results of ANCOVA indicated that the Mindful Parenting course directed to a statistically significant difference between pre-and post-test scores which led to decreasing scores of anxiety, depression and aggression. So that in the Post-stage, after controlling for pre-test scores, the experimental group reported less anxiety, depression and aggression compared to the control group. Conclusion: With regard to the effective use of Mindful Parenting course to decreasing symptom-related with anxiety, depression and aggression in mothers of girls with Oppositional defiant disorder, the training program should be directed toward reducing stress and promotion of general health in this group of people.  }, Keywords = {Oppositional defiant disorder, Mindful Parenting program, Anxiety, Depression, Aggression}, volume = {21}, Number = {6}, pages = {576-590}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1363-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1363-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Tahmasebi, H and Bokaeian, M}, title = {The Study of Pantone Valentin Leukocidin (PVL) Gene in Methicillin-resistant Staphylococcus Aureus Isolated from Blood and Wound in Zahedan, Iran}, abstract ={Background & aim: Panton-Valentine leukocidin (PVL) is a Staphylococcus aureus gamma toxin. There may be a link between Meticillin-Resistant Staphylococcus aureus and Panton-Valentine leukocidin (PVL), as an important cytotoxin found particularly in severe infections. The purpose of this study was to isolate and identify Staphylococcus aureus virulence Panton-Valentine leukocidin (PVL) and methicillin resistance genes in clinical samples using PCR techniques. Methods: In the present cross-sectional study, 89 isolates were collected from blood samples and detected as Staphylococcus aureus during the period of 6 months at Ali Ebne AbiTaleb Hospital, Zahedan, Iran. Initially, the case study examples were examined by biochemical tests. Then, based on recognized standards, Staphylococcus aureus isolates were isolated. Afterwards, isolates obtained were confirm by using 16srRNA gene. Subsequently, the antibiotic susceptibility of all isolates to methicillin was determined using Cefoxitin(30µg) disk diffusion and agar screening methods. Finally, the PCR method was used to determine PVL and mecA genes. All results were analyzed by the Chi-square test. Results: Out of the total 89 isolates of Staphylococcus aureus blood isolates, 26 isolates from wounds and 63 were isolated. Most samples were obtained from female patients. According to the molecular analysis, 47 isolates (82/52%) were mecA gene and resistant to methicillin and 42 strains (47/2%) was methicillin-sensitive. Resistance to vancomycin wasn’t observed in isolates. Erythromycin and Penicillin had the highest prevalence of antibiotic resistance among isolates, respectively. Multi-resistant strains were the most PLV genes frequent. A significant relationship was observed between the resistance and the presence of Pantone Valentin (P≥0 / 05). Conclusions: Due to the frequency of mecA and PLV genes in resistant and susceptible strains of Staphylococcus aureus, and also the distribution of Pantone Valentin gene in resistant strains; therefore, based on the statistical analysis, we can conclude that there may be a connection between these two factors (P≥0 / 05).}, Keywords = {Panton-Valentine leucocidin(PVL), Staphylococcus aureus, Antibiotic resistance}, volume = {21}, Number = {6}, pages = {591-604}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1332-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1332-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Haghnegahdar, S and Baserisalehi, M}, title = {Determination of Phylogenetic Relationship Among Vibrio Parahaemolyticus Isolates from Persian Gulf and the Evaluation of their Susceptibility to Antibiotics}, abstract ={Background & aim: Vibrio parahaemolyticus is a Gram negative halophilic bacterium found in aquatic environments. This bacterium has been introduced as a cause of acute gastroenteritis following the consumption of raw and uncooked seafood. Major symptoms of Vibrio parahaemolyticus illness is watery diarrhea, abdominal cramps, Nausea, Vomiting, Fever, Headache and Bloody diarrhea. The purpose of this study was isolation and identification of Vibrio parahaemolyticus from Persian Gulf and the determination of their phylogenetic relationship. In addition, antibiotic susceptibility of the isolates was evaluated in order to achieve maximum information concerning a drug of choice. Methods: In this study, 89 samples of water, sediments, fish and shrimp were collected from different regions of the Persian Gulf. All samples were asssessed for phenotypic and molecular isolation and identification of Vibrio parahaemolyticus. Then the positive and negative  strains of conagua vibrio parahaemolyticus were determined based on hemolysin production. the identification and phylogenetic relationship  were  analyzed using the mega-6 software. Finally susceptibility of Kanagawa positive Vibrio parahaemolyticus to antibiotics was evaluated by disk diffusion method and minimal inhibitory concentrations of effective antibiotics were assessed using double serial dilution method. Results: A total of nine Vibrio parahaemolyticus were isolated and identified. Of all isolates five strains were Kanagawa positive and four were Kanagawa negative. All isolates exhibited phylogenetic relationship to each other except one strain (NSP1). The results obtained from antibiotic susceptibility of Kanagawa positive  Vibrio parahaemolyticus isolates illustrated that most of the isolates were resistance to Vancomycin, Oxacillin, and Amikacin and susceptible to Trimetoprim Sulfometaxazole respectively. In addition, the lowest Minimal inhibitory Concentration (MIC) value was found for Sulfometaxazole  and highest MIC value was found for Nitofuran. Conclusion: The present study illustrated that both pathogenic and nonpathogenic Vibrio parahaemolyticus existed in the persian Gulf. On the other hand these bacteria that could facilitate phylogenetic relationship with each other because of  horizontal gene transfer among them.Trimetoprim Sulfometaxazole could be considered a durg of choice for treatment of the patient suffering from Vibrio parahaemolyticus infections.  }, Keywords = {Vibrio parahaemolyticus, phylogenetic relationships, antibiotic susceptibility, 16SrRNA, Persian Golf}, volume = {21}, Number = {6}, pages = {605-616}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1227-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1227-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Asgari, K and Hashemi, B}, title = {Comparing the Performance of Five Brain Systems and mood changes (Anxiety and Depression) with the Level of Estrogen in Postmenopausal and Premenopausal}, abstract ={Background & aim: One of the most critical stages of women’s lives is menopause. It is caused by permanent cessation of ovarian function and decreased of estrogen level. Menopause has numerous side effects (Physical and psychological). Recent neurophysiological data suggest that the function of central nervous system may be susceptible to modulation by estrogen. The aim of this study was to compare the performance of the five important parts (prefrontal cortex, cingulate gyrus, limbic system, basal ganglia and temporal cortex) of the brain and mood changes (anxiety and depression) with the level of estrogen in postmenopausal and premenopausal women in Isfahan. Methods: In the present descriptive study 200 women (100 postmenopausal women 45 to 65 years old and 100 women, premenopausal 20 to 40 years old) were selected by sequentially available from health centers of Motahari, Sajjad and Amin Askariyeh Hospital. The research instrument was a brain systems questionnaire of 101 questions (Brain systems) with 89/0 reliability to evaluate five important system functions in the brain (prefrontal cortex, cingulate gyrus, limbic system, basal ganglia and temporal lobe) and Beck Depression Inventory with reliability of 93 / 0 and anxiety with reliability 92/0 to assess depression and anxiety. The data was analyzed using descriptive statistics (mean and standard deviation) and inferential statistics (MANOVA MANOVA) analysis. Results: significant differences were found in five brain system functions (prefrontal cortex, cingulate gyrus, limbic system, basal ganglia and temporal cortex) and levels of estrogen and anxiety of two the groups of postmenopausal and premenopausal women (P<0.001) but no significant difference was observed regarding depression of these groups (P>0/001).         Conclusion: It seems that in addition to the role of estrogen in the female reproductive system, it also has an impact on the nervous system and its various parts. Following the reduction of estrogen in postmenopausal women, the modulation of brain functions is affected. So the two-way interaction and convergence among secretion of hormones with brain function and mood changes such as anxiety and depression could be explained.  }, Keywords = {Estrogen, Anxiety, Depression, Brain systems, Postmenopausal Women}, volume = {21}, Number = {6}, pages = {617-629}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1228-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1228-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Amiri-Siavoshani, M and AlaviMilani, M and Shabani, A and TafazzoliHarandi, H and Afrakhteh, M}, title = {Determining the Effect of Early Feeding after Cesarean section Compared with Regular Diet on the Gastrointestinal Function of Women Referred to Tajrish Hospital, Iran}, abstract ={Background & aim: Early feeding after cesarean section can have beneficial effects, however, no sufficient study has been conducted in this area. The aim of this study was to determine the effects of early feeding on the gastrointestinal complications in women after cesarean section and comparing it with a regular diet.   Methods: The present randomized-clinical-trial study was conducted on 160 women who admitted to Shohada hospital and underwent cesarean section in 2011-2012. The inclusion criteria included women with gestational age more than 37 weeks, singleton pregnancy, having at least 8 hours of fasting, and regional anesthesia (spinal cord), respectively. After registration of demographic characteristics and pregnancy, women were randomly divided into two groups: Early feeding (2 hours after completion of the operation, 250 ml filtered juice, tea and biscuits style regime in the next 2 hours and 2 hours after the usual diet) and the usual power (8 hours of operation clear liquid diet the day after the usual diet) groups. Presence of gastrointestinal symptoms in 2, 4, 8 and 12 hours after surgery, time to the bowel sounds auscultation, passage of flatus and stool were recorded. Data were analyzed by SPSS software version13.The significance level of p-value was considered <0.05.   Results: The prevalence of gastrointestinal symptoms (nausea, vomiting, loss of appetite, abdominal distension, feeling of flatulence and abdominal cramp) was significantly higher at 2 and 4 hours after operation and in early feeding group and after 8 hrs. in surgery of normal diet respectively(P<0.05). There was no significant difference in symptoms between the two groups observed 12 hours after surgery (05/0 p <). The bowel sounds auscultation and passage of flatus were recorded earlier in early feeding group (P=0.001), while the recorded time for passage of stool was not different between the two groups (P>0.05).   Conclusion: Early feeding caused the acceleration of gastrointestinal symptoms, earlier bowel sounds auscultation and earlier utilization of gas. It is recommended to investigate the different diets and examined the level of compliance and satisfaction.  }, Keywords = { Cesarean section, post-cesarean feeding, routine regimen, early feeding}, volume = {21}, Number = {7}, pages = {630-640}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1130-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1130-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Ramezani, AR and Gaeini, AA and Hosseini, M and Mohammadi, J}, title = {Effect of Endurance, Strength and Combined Training on Lipid Profile, Insulin Resistance, and Serum Adiponectin Levels in Inactive Obese Children}, abstract ={Background & aim: Nowadays, Iranian lifestyles are changing, especially children may be effected by the increase of cardiovascular diseases. Studies have shown that different methods of exercise are the most important determinants of cardiovascular risk factors. The aim of this study was to survey the lipid profile, insulin resistance, and adiponectin levels following eight weeks of endurance, strength and combined training in inactive obese children. Methods: The present quasi-experimental field was conducted on Sixty obese male children (age: 8-12 years, BMI between 30-35 kg/m2 according to the World Health Organization) who were purposefully selected and randomly divided into four experimental groups of 15 individuals including endurance exercise, resistance exercise, combined exercise and control. Exercise training programs were performed four times a week for eight weeks. To assess variable changes, ANOVA with repeated measurement and one way ANOVA was used. Results: Results showed that after three types of exercise training  the BMI, total chlostrol, TG, LDL, VLDL, and insulin resistance significantly decreased in experimental groups compared to control group (P=0.001). Serum HDL and adiponectin was significantly increased after different training in experimental groups in comparison to control group (P=0.001).  Conclusion: According to the findings, it is suggested that among three types of exercise applied in this study, particularly, endurance training is use to prevent and reduce the incidence of cardiovascular diseases and obesity-related disorders in inactive obese children. .}, Keywords = { Exercise training, Obese Children, Resistance Insulin, Adiponectin, Lipid profile}, volume = {21}, Number = {7}, pages = {641-654}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1446-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1446-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Karimpour, F and Razavi, SH and Tkhruni, F}, title = {Evaluation and Comparison of Lactic Strains Isolated from Traditional Iranian Dairy Products (Richal Shiri) with Armenian Dairy Products on Control of Food Spoilage Agents}, abstract ={Abstract Background & aim: Some bacterial metabolites isolated from fermentative products have antibacterial properties against food spoilage bacteria. The aim of this study was to evaluate the antibacterial properties of the isolated strains of traditional Armenian dairy products including cheese and traditional yogurts (Matson) and Richal  shiri as a traditional dairy products from Iran. Material and method: In the present experimental study, bacterial strains were isolated, and subsequently the antibacterial activity of supernatants of strains on several types of spoilages bacteria such as Salmonella  was assessed. In addition, isolated strains from Rachel shiri showed  a good  antibacterial properties against Salmonella typhimurium. Results: The isolated strains were significantly reduced food contamination and increased the shelf -life. Furthermore, isolated strains from Richal shiri showed a good antibacterial properties against Salmonella typhimurium Conclusion: LAB strains isolated with appropriate inhibition, fermented power as a natural preservative and pragmatic as new products may be used in the dairy industry.}, Keywords = { Antibacteral activity, Richal Shiri ,Lactic Acid Bacteria, Armenian Traditional Dairy}, volume = {21}, Number = {7}, pages = {655-668}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1408-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1408-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Gashmardi, N and Mehrabani, D and Hosseini, SE and Edalatmanesh, MA and Khodabandeh, Z}, title = {The Healing of Bone Marrow-Derived Stem Cells on Motor Functions in Acute Spinal Cord Injury of Mice}, abstract ={Background & aim: Spinal cord injury is a devastating damage that can cause motor and sensory deficits reducing quality of life and life expectancy of patients. Stem cell transplantation can be one of the promising therapeutic strategies. Bone marrow is a rich source of stem cells that is able to differentiate into various cell types. In this study, bone marrow stem cells were transplanted into mice spinal cord injury model to evaluate the motor function test. Methods: Bone marrow stem cells were isolated from 3 mice. Thirty six mice were randomly divided into 3 groups: the control, sham and experimental. In sham group, mice were subjected to spinal cord compression. In experimental group, one day after lesion, isolated stem cells (200,000) were injected intravenously. Assessment of locomotor function was done by Toyama Mouse Score (TMS) after 1, 2, 3, 4, 5 week post-injury. The data were analyzed using one-way Analysis of Variance and Tukey tests and statistical software Graph Pad and SPSS.P > 0/05 was considered as significant difference.  Results: The score of TMS after cell transplantation was higher in cell transplantation group (experimental), while it was significantly higher after fifth week when compared to other groups. Conclusion: The increase in TMS score in cell transplantation group showed that injection of stem cells in acute spinal cord injury can have a therapeutic effect and promote locomotor function.}, Keywords = {Bone marrow, Mesenchymal stem cells, Locomotor function, Spinal cord injury, Toyama Mouse Score}, volume = {21}, Number = {7}, pages = {669-681}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1375-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1375-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Rahimi, N and SamaniJahromi, E and ZolghadriJahromi, S}, title = {The investigation of hydroalcholic extract of Ducrosia anethifolia boiss on the testis tissue and testosterone hormone}, abstract ={Background & aim: Medicinal plants with natural active substances and with lower side effects could be used as effective drugs in the treatment of many diseases. In recent years, the effects of reducing blood sugar, lipids, pain relief back pain of Ducrosia anethifolia has have been reported. The purpose of this study was to investigate the effect of hydro-alcoholic extract of Ducrosia anethifolia on Testosterone hormone and the histological changes of testicle in male adult rats. Methods: The present experimental study was conducted on 56 male adult Wistar rats.  The animals were divided into five groups: the control group (without treatment), the sham group (received the solution via gavage for 21 days). The experimental group 1, 2, 3 received hydro-alcoholic extract of Ducrosia anethifolia with 140,280,560 mg/kg dose per the body weight were gavaged for 21 subsequent days. On 22nd day, the animals were euthanized and the rat testes placed in 10% formalin for evaluating the histological changes. The 5 micron- sections from testicle were provided and stained by the hematoxylin - eosin method. The blood serums were collected and the level of testosterone was measured. Data were analyzed using SPSS statistical software and Duncan test and ANOVA at the significant level (p <0.05). Results: Statistical analysis showed a significant decrease in the number of spermatocytes, spermatids, spermatozoa and testosterone levels in Groups 1, 2 and 3 compared with the control group and the sham group. Conclusion: According to the results of this study, the Ducrosia anethifolia extract reduces the number of germ cells, the level of testosterone and spermatogenesis in male Wistar rats.}, Keywords = { Ducrosia anethifolia, Testosterone, Testicle, fertility, Rat}, volume = {21}, Number = {7}, pages = {682-693}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1389-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1389-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Noroozi, S and Pourshahryai, MS and Lotfi, M}, title = {The Efficacy of Combination of Cognitive-behavioral Therapy and Choice Theory and Obsessive-compulsive Disorder: A Case Study}, abstract ={Background & aim: Obsessive - Compulsive Disorder (OCD) is a disabling disorder that affects one's performance, while the effectiveness of cognitive - behavioral therapy has been shown in several studies, but recurrences of the disease is reported by patients. The aim of this study was to evaluate the efficacy of the combination of cognitive-behavioral therapy and choice theory and obsessive-compulsive disorder on patients referred to psychological clinics in Arak, Iran. Methods: In the present case study, 3 females diagnosed with OCD on the bases of Yale-Brown scale (Y-BOCS) were chosen. They were trained 8 sessions which included cognitive-behavioral treatment and choice theory.  Five sessions of 8 sessions were on the bases of cognitive behavioral therapy and other sessions were on the basis of choice theory. Finally, the results were presented using tables and graphs. Results: The results of the Yale-Brown scale (Y-BOCS) was used as a pretest and posttest assessment and self-report form (Report of the clients who had a 5-degree scale) demonstrated the effectiveness of integrating of two cognitive-behavioral and choice theory. Conclusion: According to the results, it was concluded that people with knowledge of the choice and intrinsic motivation in the using cognitive-behavioral trainings (Relaxation, recognition of cognitive distortions, avoiding the respondents) are efficient in reducing symptoms of obsessive-compulsive will operate. Combining of these two approaches in advancing therapeutic targets in the treatment of patients with obsessive-compulsive disorder can be effective.}, Keywords = {Obsessive compulsive disorder, Cognitive Behavioral therapy, Choice Theory}, volume = {21}, Number = {7}, pages = {694-706}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1282-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1282-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Panahpuri, P and Moghadasi, M}, title = {The Relationship between the Prevalence of Obesity and Overweight Lifestyle among Female students aged 7 to 12 in Yasuj, Iran}, abstract ={Abstract Background & aim: The prevalence of obesity and overweight in the female students aged 7 to 12 in Yasuj is not well known. Thus, the aim of this study was to estimate the association among lifestyle status with obesity and overweight prevalence in girl students aged 7 to 12 in Yasuj. Methods: The present cross-sectional descriptive study was ran on 352 (girls) students aged 7-12 years old. The subjects were selected via a step-wise random sampling. Height and weight of the subjects were measured by standard methods and body mass index (BMI). Overweight and obesity were defined on the 85th and 95th percentiles of BMI for age and sex as proposed by Centers for Disease Control (CDC). Lifestyle status and family conditions were collected by a standard Baecke questionnaire. Correlations between the variables were determined by the Spearman correlation. Results: The prevalence of obesity, overweight and underweight in 7-12 years old students were 6.5%, 22.1% and 13.3% respectively. The results showed that there was a significant relationship between BMI with parent’s BMI in 7 years old students, a significant relationship between BMI with daily commute to school in 8 years old students, a significant relationship between BMI with fast foods and chips consumption pattern in 9 years old students, a significant relationship between BMI with father’s educational levels, fathers’ BMI and time spend for exercise in 10 years old students, significant relationship between BMI with father’s educational levels, fathers’ BMI, watching TV, fast foods, cola and chips consumption pattern and time spend for exercise in 11 years old students and significant relationship between BMI with fathers’ BMI and watching TV in 12 years old students (P<0.05). Generally, there were inverse relationships between BMI with time spend for exercise and positive relationship between BMI with fast foods consumption pattern and father’s BMI (P<0.05). On the other hand, no significant relationship was observed between BMI with daily commute to school, rank of birth, number of families, parent’s educational levels, mother’s BMI and sitting activities. Conclusion: the results of the study showed that the consumption of fast foods and engaging in physical activity and body mass index is the main factors in determining of school girls aged 7 to 12 years in Yasuj. Thus, the need for greater mobility and improve nutritional patterns are emphasized.}, Keywords = { Body mass index, Obesity, Overweight, Girls students, Lifestyle, Exercise}, volume = {21}, Number = {7}, pages = {707-717}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1237-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1237-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Sajjadikhah, G and Salajegheh, S}, title = {The Relationship between Management, Career Planning and Career Development of Medical and Non-medical Faculty Members of Kohgiluyeh and Boyerahmad Province, Iran}, abstract ={Abstract Background & aim: There are many mechanisms for the development of human resources, which career development is one of its central components. The aim of this study was to determine the factors related to career development faculty members (Medical and Non-medical) of Kohgiluyeh and Boyer-Ahmad province, Iran. Methods: The present paper was a cross-sectional, descriptive correlation method study.  The study population consisted of 535 faculty members (medical, government, NGOs) in Kohgiluyeh and Boyer province, Iran, of which 400 participants were randomly selected for the present study. Data were collected through standard questionnaires as a research tool, of career development, career planning and career management for data analysis and statistical tests including linear regression, t-test, regression, and correlation coefficient was used. Results: Career development status and its related factors (Career management and career planning) scientific faculty members was desirable. The findings show that between career planning and career management, career development, a significant positive correlation was observed (P <!-- 05). So that 33.3% of the planned changes of career path development was related to career path planning, and 16.2 % of career path development change was related to career path management. Conclusion: The results indicate that the design and implementation of individual career planning and career management career by leading the development of the organization. These three lead to the realization of collaborative environment, work-life balance, organizational justice, organizational learning and organizational evaluation of individual activities which are helpful and effective.}, Keywords = {Career Development, Career Management, Career Planning}, volume = {21}, Number = {7}, pages = {718-729}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1477-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1477-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {KarampourQipchaq, Z and Heidari, R and AbtahiFroushani, SM and Farokhi, F}, title = {The Effects of Combined Atorvastatin and Zinc Oxide on Some Markers of Oxidative Stress in the Hippocampus in Streptozotocin-induced Diabetic Rats}, abstract ={Background & aim: Diabetes is a metabolic disorder characterized by hyperglycemia. Hyperglycemia through enzymatic and non-enzymatic processes causes induction of spontaneous oxidation of glucose and, by stimulating the production of active oxygen and nitrogen components, leading to oxidative stress. Thus, according to the antioxidant effects of atorvastatin and zinc oxide, the aim of this study  was to investigate the combined effect of atorvastatin and zinc oxide on oxidative stress and antioxidants in diabetic rats. Methods: In the present experimental study, 50 female Wistar rats were selected randomly and divided into five groups of 10 (n=10) including : normal control (NC), diabetic control (DC), diabetic rats treated with, atorvastatin (20mg/kg daily-orally) (DA), zinc oxide (30mg/kg daily-rally) (DZ) and combination of each drug in half-dose (daily-orally) (DAZ), were each treated separately. Diabetic rats were induced by injection of 60 mg per kg of body weight of streptozotocin (STZ) intraperitoneally.All treatments were dissolved in distilled water for four weeks. After completion of treatment (forth week), weight and blood sugar were measured and then compared with data measured  on weight and blood sugar in the weeks before the start  and second week of the study. The lipid peroxidation level (MDA), the activity of catalase (CAT) and total antioxidant capacity (TAC) as an indicator of oxidative stress were measured in the hippocampus. Data were analyzed using ANOVA and Tukey tests. Results: Zinc oxide and atorvastatin alone rather than decrease blood sugar, reduced the complications of diabetes, including oxidative damage and combination  of both reduced levels of diabetic complications led to the significant decrease in blood glucose levels and inhibiting the animal lose weight. Conclusion: It seemed that the combination of atorvastatin and zinc oxide have synergistic benefits to control blood sugar levels and oxidative stress, and also resulting in control  of diabetes.}, Keywords = {diabetes, atorvastatin, zinc oxide, oxidative stress, the hippocampus of rats}, volume = {21}, Number = {8}, pages = {730-745}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1445-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1445-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Parvizi, A and Ghasemnian, A and Rahmani, A}, title = {Effect of 12 weeks aerobic exercise for along with folic acid supplementation on the levels of the ghrelin hormone amount of food intake and weight changes of female Wistar rats}, abstract ={Background & aim: Results of numerous studies have shown that approximately 1 to 78 percent of female athletes suffer from eating disorders. On the other hand, it has been mentioned that folic acid could increase appetite. The ghrelin hormone is known as a strong stimulant for appetite. Therefore, to clarify the role of exercise and food intake of folic acid on plasma acylated ghrelin the study aim was to evaluate the effect of 12 weeks of aerobic training on ghrelin supplementation of folic acid and quantity of food intake and weight change in female rats. Methods: In the present experimental study, 24 rats were randomly divided into three groups of 8 including: control, training and training along with folic acid supplementation. The training protocol consisted of aerobic exercise running on a treadmill for 12 weeks (5 days a week). Standard meal and water were freely provided for the subjects and in the supplement group 10 mg dissolved folic acid per liter of water were used and then the food intake and body weight was measured every week. 24 hours after the last session of training and 8 hours of overnight fasting, blood and tissue samples were collected and hormones levels were measured using Eliza method. To data analyzing, one way ANOVA and Tukey post hoc test was used. Results: The results showed that 12 weeks of  aerobic training with folic acid supplementation had significantly reduced serum acylated ghrelin levels (P<0.05), but no sign on stomach tissue acylated ghrelin was seen (P>0.05). The 12-week aerobic training with folic acid intake in comparison with other groups significantly increased food intake and body weight gain (p < 0.05). Conclusion: According to the acylated ghrelin reduction and lack of change in the stomach acylated ghrelin with increased food intake and body weight in rats, it seems that taking folic acid supplements inactive athletes with another strong mechanism, increasing consumption of food and influence on appetite center.}, Keywords = { Aerobic training, Folic acid, Acylated ghrelin, Weight changes}, volume = {21}, Number = {8}, pages = {746-756}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1474-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1474-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Farsi, S and AzarbayjaniMA, and Hosseini, SA and Pirei, P}, title = {Response of Serum Levels of ICAM-1 VCAM- 1and CRP to High and Moderate Endurance Trainings in Sprague Dawley Male Diabetic Rats}, abstract ={Background & aim: Diabetes is a chronic disease which induces a rise in inflammatory response and endothelial disorders. The aim of present study was to review the response of ICAM-1, VCAM- 1 and CRP serum level to high and moderate endurance trainings in diabetic rats. Methods: In the present experimental research, thirty-two diabetic male sprague dawley rats were selected and based on their blood glucose, they were divided into four groups of eight: (1) diabetes sacrifice first week, (2) diabetes sacrifice last week, (3) moderate intensity endurance training and (4) high intensity endurance training and for review the effects of diabetes induction 16 healthy rats divided in two groups of healthy sacrifice first week and healthy sacrifice last week. Rats of high and moderate intensity endurance trainings ran on treadmill for eight weeks, three sessions per week and 60 minutes with intensity of 10- 17 and 17- 28 meter per minute. To analyze the data, the Kolmogorov-Smirnov tests, ANOVA with Tukey test was used. Results: Results indicated that induction of diabetes resulted in a significant increase in ICAM-1 (p=0.001), VCAM- 1 (p=0.001) and CRP (p=0.001) respectivly. Eight weeks moderate and high intensity endurance training showed a significant reduction on ICAM-1 (p=0.001), VCAM- 1 (p=0.003) and CRP (p=0.001) and such reduction on ICAM-1 (p=0.04), VCAM- 1 (p=0.04) and CRP (p=0.001) respectively. Also moderate and high intensity endurance trainings had equal effects on ICAM-1 (p=0.53), VCAM- 1 (p=0.90) and CRP (p=0.99) on diabetic rats. Conclusion: Moderate and high intensity endurance trainings had equal effects on reduction of ICAM-1, VCAM- 1and CRP on diabetic rats.}, Keywords = { intensity endurance training, ICAM-1, VCAM- 1, CRP}, volume = {21}, Number = {8}, pages = {757-771}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1483-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1483-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Notaj, A and AbtahiFroushani, SM and Khezri, Sh}, title = {The Effect of Quercetin on the Physiological Funtions of Rats Peripheral Plood Neutrophils in Vitro Condition}, abstract ={Background & aim: In traditional medicine, medicinal plants containing flavonoid compounds were used for several years in the treatment of various diseases. Quercetin is one of the flavonoid composition family that has a maximum antioxidant flavonoid content. The aim of this study was to investigate the physiological features of rats peripheral blood neutrophils treated with quercetin.   Methods: In the present experimental study, the rats peripheral blood neutrophils was isolated and then teated with various concentrations of quercetin (0, 5, 10 and 20 µg/ml). The metabolic activity, phagocytosis capabilities, germicidal and respiratory burst of neutrophils were measured. Kruskal-Wallis test was used to compare the analysis.   Results: The results demonestrated that the respiratory burst of neutrophils treated by quercitine was significantly increased at minimum concentrations of 10 micrograms per ml. Simmilary, the phagocytic ability of neutrophils was significantly increased at minimum concentrations of 10 micrograms per ml. Albith, the phagocytic ability of neutrophils was increasesd in 5 micrograms per ml, howevet this finding didn’t show any significant change.Moreover, the application of quercetin at minimum concentrations of 10 micrograms per ml lead to a significant reduction in killing and survival of neutrophils in the treatment group compared to that of the control group (P<0/05).   Conclusion: Quercetin could be considered as a natural immunomodulator of innate responses. This might be due to the inflammation control of neutrophils.    }, Keywords = {Quercetin, Neutrophil, Rat}, volume = {21}, Number = {8}, pages = {772-786}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1433-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1433-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Narimani, M and BaniTalebi, E and SHokri, B and Soheili, B}, title = {The Effect of 12 Weeks Individualized Combined Exercise Rehabilitation Training on Physiological Cost Index (PCI) and Walking Speed in Patients with Multiple Sclerosis at all Levels of Physical Disability}, abstract ={Background & aim: Most research on the effects of exercise on people with MS rehabilitation exercises sclerosis (MS)  have been carried out on patients with low to moderate disability, but research on patients with different severity of disability (physical disability scale of zero to 10) still has to be carefully considered. The aim of this study was to investigate the effects of twelve weeks of rehabilitation exercises personalized compound exercise on physiological cost index (PCI) and average speed walking in patients with MS at various levels of disability. Methods: The present research was a semi-experimental practical study. Thus among female patients admitted to the MS Association of Shahrekord city, 96 people were chosen on the basis of physical disability scores and divided into three groups. The first group consisted of less than 5/4 a total of 44 people, the second group between 5/65 and 5/6 up third of each 26 patients were then randomly assigned to an experimental group and a control group. Afterwards each group was divided randomly into an experimental group and a control group. The first group (the scale of disability less than 4.5), N= 44. The second group (the scale of disability 5 - 6.5), N=26. Also 26 patients were in the third group (the scale of disability 6.5 and above). In addition, they were divided into 6 experimental and control groups. Training programs for experimental groups were 12 weeks, three sessions per week and one hour for each session. Factors such as physiological cost index and walking speed were measured with the appropriate tools before and after training. The experimental groups of 1, 2 and 3 each did their own intervention, while the control groups received only stretching exercises. Analysis of data obtained from 96 patients studied was done using descriptive statistics and the analysis of covariance and paired comparing of the adjusted means (P<0.05). ‌‌‌ Results: A significant difference in walking speed or low-intensity failure of the first group ( p=0.000), moderate intensity or the second group (p=0.012) and severe and the third group (= p=0.000), in the experimental group were observed compared with the control group before and after exercise. In addition: significant differences was seen in PCI of patients with low disability intensity of the first group (p= 0.023), moderate intensity or the second group (p= 0.022) and severe or the third group (p= 0.0001), in the experimental group compared with the control group before and after exercise. ‌‌‌ Conclusions: Implementation of Rehabilitation exercises was affective on the comprehensive exercise on MS patients' recovery and reduced the physiological costs, and consequently improved the performance of walking in their physiological and reduced fatigue. According to the results, it is recommended that experts use these exercises as a complementary therapy alongside drug treatments for M.S patients.}, Keywords = {Multiple sclerosis, combined rehabilitation, individualized, PCI, walking speed}, volume = {21}, Number = {8}, pages = {787-803}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1480-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1480-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Firoozi, MR and Noushadi, N and Kazemi, A}, title = {Determining the Psycho Social Health Indicators in Children and Adolescents in Kogiluyeh and Boyer Ahmad Province}, abstract ={Abstract Background & aim: Nearly a decade the World Health Organization has tried to provide a unique definition of community mental health. But due to the complexity of psychosocial and cultural context, it is not provided. The purpose of the study was to determine indexes community mental health of children and adolescents in the province of Kohgiluyeh and Boyerahmad. Methods: This study was conducted as a hybrid approach (qualitative and quantitative). Delphi technique was used in qualitative research. In the current study, 31 experts, children and adolescents of Social Welfare organizations were selected as snowball method throughout the province of Kohgiluyeh & Boyerahmad. The primary data to run the Delphi Technique was gathered in three stages from the participants. The quantitative data were analyzed using factor analysis. Results: The results indicated that the main indicators of psychosocial health lie in intrapersonal (emotional self-awareness, risk-taking and self-respect), interpersonal (participation, social responsibility, and social relationships), stress (stress management and controlling emotions) and adaptability (flexibility and happiness) components. The results also showed that decreasing gender-related discriminations and rise in the educational level of parents are the major strengths and lack of required standards in child-care centers, lack of involvement of young adolescents in decision-making and lack of social skills in families are the major weaknesses of psychosocial health. Conclusion: Given the right conditions, and in order to safeguard children and adolescents against the grave consequences awaiting them, the organizations charged with the responsibility should raise the children and adolescents in such a way that they meet the professional needs of the society and feel responsible when it comes to these responsibilities and commitments. }, Keywords = { Psychosocial Health, Children, Young Adolescents}, volume = {21}, Number = {8}, pages = {805-815}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1373-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1373-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Shakour, M and Yamani, N and Ehsanpou, S and Alizadeh, SH}, title = {Reproductive Health Needs Assessment of Girl and Boy Teenagers}, abstract ={Background & aim: Reproductive health of puberty is very important in the cycle of Life. Adolescence is a very important period of time in cycle of life and it is followed by physical, psychological and social changes. Therefore the aim of this study was needs assessment of reproductive health for adolescence as a first and principal step in curriculum planning for health services. Methods: This study was qualitative like the most needs assessments and the method was content analysis. Data gathering was done by semi structured interview. We used two focus groups (7and 10persons) for needs assessment of reproductive health between girls, and personal interview with 10 boys. We did content analysis and then extracted the main themes and sub themes. Results: Adolescent girls had diverse needs in four groups: experiences related to menstruation and hygiene, social needs, sexual needs and psychological needs. Also adolescent boys had three groups of needs like physical changes, psychological and sexual needs. In physical needs group they had some needs like no knowledge of symptoms of adolescence, no knowledge of hygiene related to puberty. In psychological needs group they had some needs like feeling depression and in sexual needs group they had some needs like tendency to make contacts with girls, no knowledge of communication with people with different sex. Conclusion: Education and the systematic planning in reproductive health matters are necessary for parents, teachers and adolescents, and they are known as the prior needs.}, Keywords = {Puberty, Reproductive health, Needs assessment}, volume = {21}, Number = {8}, pages = {816-829}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-537-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-537-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Panjehband, SU and Enayat, H}, title = {The Process of the Formation of Post-marital Relationship from the Perspective of Men}, abstract ={Background & aim: The Increasing phenomenon of post-marital relationship in the society has had adverse consequences. One of the consequences, is the instability of family foundations and the disintegration of social cells (families). The aim of this study was to determine the formation process of meta-marital relationship from mens viewpoint. Methods: The methodology of this study was grounded theory method. 16 men with purposive sampling method were selected as participants in Gachsaran city, Iran. The data was obtained through semi-structured interviews and was analyzed due to the three stages of "open, axial and selective" coding. Results: Findings of the study were categorized in three major categories: the emotional disproportionate relationship-sexual between men and women's, and, socio-cultural structure predisposing of men and women's sexual dissatisfaction and incorrect criteria for choosing a spouse and one core category named extramarital relationship, hiding object was created. Conclusion: Men Narrative participants indicated that due to spouse selection of "being unemployed, elder girl age, girl escape from his parental house, the divorced couple, and of man being widowed”, were are indications thay they were forced to be married. Also, due to “employed women and pressing sexual desire “was the tool selection. In most of these marriages, men and women had a great age difference, and initially there was no love among them. The prevailing of cold atmospherel and indifference in the marital relations caused led to the fact that they could not meet the emotional needs of each other. Moreover, the culture of modesty dominant over most of the Iranian families has banned the talk of sex and its quality not only in public environments such as schools, universities, radio and television, but also in the family and even between men and women as a "taboo", and these couples can not talk about the quality of their sex life with eachother. At this situation, the women with post-marital relationship have expressed their objections by hidden relationships.}, Keywords = { Infidelity, Qualitative methodology, Grounded theory, Latent appose }, volume = {21}, Number = {8}, pages = {830-845}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1353-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1353-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {MadadiJaberi, M and VahidianRezazadeh, M and Mogharnasi, M and KarajiBani, M}, title = {The Effect of 8 Weeks of Aerobic Training and Consumption of Hydro-alcoholic Extract of Nettle on Apelin and hs-CRP plasma Levels of Overweight and Obese Women}, abstract ={Background and aim: The use of exercise along with herbal supplements is one method proposed for controlling obesity and its complications. The aim of this study was to investigate the effect of 8 weeks aerobic training and use of hydro-alcoholic extract of nettle on levels apelin and hs-CRP plasma in overweight and obese women. Methods: The present quasi-experimental study was conducted with blind randomized clinical trial. 46 overweight and obese women (body mass index greater than 25 kilograms per square millimeter two, aged 25-45 years) were selected purposefully and randomly divided into four groups of: aerobic training + hydro alcoholic extract of nettle, aerobic exercise + placebo extract of nettle and placebo. The intervention group and placebo received 8 mg of hydro alcoholic extract of nettle 8 ml of water-soluble daily for 8 weeks respectively. Aerobic exercise ergometer for 8 weeks, 3 sessions of 16 to 30 minutes with the intensity of 60-75% heart rate was reserved. In two pre and post-test after 14 hours of fasting at the same conditions, blood samples were collected. The ELISA method was use to assess levels of plasma apelin and hs-CRP d. Data obtained were analyzed using the Kolmogorov-Smirnov test, ANOVA, t-test and LSD test. Results: The results showed that the levels of hs-CRP were significantly different in comparison among the groups as well as in groups of aerobic exercise + hydro alcoholic extract of nettle, nettle and hydro-alcholic aerobic exercise + placebo significant reduction was observed (p>0.05). Conclusion: It seems that consumption of Nettle extract along with aerobic exercise through Weight loss, body fat percentage and BMI, play an effective role in control of obesity and reducing of inflammatory Apelin markers and hs-CRP in obese women}, Keywords = { Chosen aerobic exercise, Nettle Hydro-alcoholic extract, Apelin, hs-CRP, Overweight}, volume = {21}, Number = {9}, pages = {846-859}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1514-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1514-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Khazaei, M and Mirazi, N}, title = {The effect of Nigella Sativa Seed Extract on Male Rats Kidneys Induced by Gentamicin}, abstract ={Background and aim: Gentamicin is an aminoglycosides antibiotic which is used to treat several types of bacterial infections. The aim of this study was to evaluate the effects of Nigella sativa extract on renal toxicity in rats induced by gentamicin. Methods: In the present experimental study, 42 Wistar male rats were divided into 6 groups of 7 includes: control (normal saline 2ml/kg, i.p), gentamicin (gentamicin80mg/kg/day, i.p), positive control (400mg/kg NSE, i.p) and treated groups 1, 2, 3 (gentamicin 80mg/kg/day+ NSE 200, 400 and 800 mg/kg respectively, i.p). Nigella sativa extract was injected for 7 days after a ten days period of gentamicin injection. Results: Gentamicin caused necrosis and inflammation in the renal cortex and medullary tissues. Treatment with Nigella sativa seed extract significantly decreased serum creatinine, BUN and serum LDH in treated groups compared with the group receiving gentamicin. The greatest impact was created in high dose (P=0.001). Conclusion: Nigella sativa seed extract reduces inflammation caused by receiving gentamicin in kidney tissue and a significant reduction in creatinine, urea nitrogen and lactic dehydrogenase enzyme in treated mice compared with the control group.}, Keywords = {Nigella sativa, Nephrotoxicity, Gentamicin, Rat}, volume = {21}, Number = {9}, pages = {860-872}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1427-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1427-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Khademi, Y and Azarbayejani, MA and Hossini, SA}, title = {The impact of high intensity aerobic interval training (HIIT) and flaxseed oil on ICAM-1 gene expression in heart tissue in male Wistar rats}, abstract ={Abstract Background: The prevalence of cardiovascular disease may be due to inflammation and systemic inflammation plays an important role in the development and progression of atherosclerosis. ICAM-1 is one of the important factors in the pathogenesis of atherosclerosis is an inflammatory effect of physical activity and plant protection products on the response it is not well known. Methods  Thirty Wistar rats were selected as sample. Rats were randomly divided into six groups of five, including control, exercise, extracts dose of 10 mg / kg, extract dose 30 mg / kg, a dose of extract practice mg / kg 10, and extracts Practice dose of 30 mg / kg, respectively. Training groups, five sessions per week for 10 weeks, intense interval training involves running on a treadmill with an intensity of 90 to 95 percent of VO2max for rodents, at specified hours during the day. After the rats were sacrificed and the heart tissue, and to measure gene expression of ICAM-1 and LFA-1 were used. Result Data analysis showed that the expression of ICAM-1 has been reduced in training supplement groups The expression of intercellular adhesion molecule receptor (ITG) has decreased in the exercise and supplement group. Conclusion: The results of this study show that both exercise and extract significant effect on gene expression of ICAM-1. And decreased expression of ICAM-1 was also flax oil ICAM-1 gene expression was also reduced. The findings of this study showed that the combination of training and flax oil reduces the expression of ICAM-1 compared to the control group. So it is likely that this method can be used as a way to prevent cardiovascular disease.}, Keywords = {cardiovascular diseases, inflammation, atherosclerosis}, volume = {21}, Number = {9}, pages = {873-886}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1526-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1526-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Khorramjah, M and Sarmadiyan, M and Khurshidy, D}, title = {The Effect of Moderate-intensity Aerobic Training on Serum Levels of Cystatin C with High Sensitivity, C-reactive Protein and Cardiovascular Risk Factors in Postmenopausal Women}, abstract ={Background and aim: The risk of cardiovascular disease in women increases after menopause. The aim of this study was to investigate the effect of aerobic exercise at moderate intensity levels of cystatin C  and some cardiovascular risk factors in inactive postmenopausal women. Methods: In this quasi-experimental study, 24 sedentary postmenopausal women (50-65 years) were  randomly divided into two experimental groups (n=14) and control group (n=10) groups. The experimental groups performed an aerobic training with 65 to 75% of maximum heart rate , 3 days per week for 10 weeks. Body fat percentage and serum levels of cystatine C with high sensitivity, C-reactive protein, HDL, LDL, triglyceride, cholesterol and blood pressure were measured at baseline and after training. Data were analyzed using analysis of covariance test.   Results: No significant difference was seen  after performing aerobic training on serum levels of cystatin C (p=0.761), C-reactive protein with high sensitivity (p=0.378), triglyceride (p=0.48)   ), high-density lipoprotein (p=0.54), low-density lipoprotein cholesterol (p=0.86), cholesterol (p=0.67), percent body fat (p=0.57) between the two groups. There was no significant difference between control and experimental groups in the variable maximal oxygen uptake (p = 0.035) and systolic blood pressure (p =0.04). Conclusion: It seems that short-term aerobic training have no effet on serum levels of cystatin c and some moderate-intensity cardiovascular risk factors like reactive protein C, total cholesterol, high density lipoproteins, lipoprotein help disabled density and blood pressure in  in inactive postmenopausal women.}, Keywords = {Cystatine C, C-reactive Protein, Cardiovascular Risk Factors, Aerobic Training, Menopausal}, volume = {21}, Number = {9}, pages = {887-899}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1335-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1335-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Beirami, M and Kazemi, S and Movahdy, Y and Sepahvand, R}, title = {Reducing Adolescent Rage Bullies: Study on Behavior Management Training Intervention}, abstract ={Background and aim: Adverse effects inner anger and interpersonal relationships will follow on from the other parent behavior management training and promoting and improving relations between parent-child.در این راستا هدف پژوهش حاضر بررسی اثربخشی آموزش مدیریت رفتار براساس مدل بارکلی در کاهش خشم دانش آموزان دختر و پسر قلدر دوره اول متوسطه بود. Methods: The present Experimental research used a pretest– posttest and a control group. جامعه آماری شامل دانش آموزان دختر و پسر دوره اول متوسطه شهر تبریز که در سال تحصیلی 93-1392 مشغول به تحصیل بودند. The population consisted of male and female junior high school students in Tabriz who were enrolled in the 2012-2013 school year. به منظور اجرای پژوهش پس از انجام سرند توسط معلمان و اجرای پرسشنامه قلدر/قربانی الویوس، 30نفر از کودکانی که براساس نمرات کسب شده در پرسشنامه الویوس، به عنوان قلدر طبقه بندی شده بودند به صورت تصادفی در دو گروه 15 نفری آزمایش و کنترل جایگزین شدند؛ و پس از تکمیل پرسشنامه خشم نیلسون(2000) توسط دانش آموزان قلدر؛ والدین گروه آزمایش به مدت 9جلسه (45 دقیقه ای) در برنامه آموزش مدیریت رفتار قرارگرفتند، ولی گروه کنترل هیچگونه آموزشی دریافت نکرد.Therefore, after screening by the teachers and the Nelson anger questionnaire, 30 children who, according to scores on the questionnaire were bullies, were classified randomly into two groups of 15 cases and controls were replaced and after completing the questionnaire anger Nilsson (2000) bullying by students, parents groups for 9 sessions (45 minutes each) were treated in a management training program, while the control group received no training. آزمودنی ها پس پایان جلسات آموزش مدیریت رفتار والدین ، مورد بررسی مجدد قرار گرفتند. Parent Management Training participants after the end of the session, were reviewed and followed a month later. داده ها با استفاده از نرم افزار آماری18 SPSS و با استفاده از شاخص های توصیفی و آزمون تحلیل کوواریانس چند متغیری مورد تجزیه وتحلیل قرار گرفتند. نتایج حاکی از اثربخشی آموزش مدیریت رفتاری والدین بر کاهش خشم نوجوانان قلدر (05/0 P< ) بود. Data were analyzed by the SPSS version 18 statistical software using descriptive indicators and multivariate analysis. Results: The results indicated the effectiveness of Parent Management Training to Reduce Anger of the teen bullies (P <0.05), respectively.فقط در مولفه های ناکامی و پرخاشگری بدنی تفاوت معنی داری نبود و در مقایسه اثربخشی آموزش مدیریت رفتار به دختران و پسران گروه آزمایش، نتایج نشان داد که در بین دختران و پسران گروه آزمایش تفاوت معناداری وجود ندارد این نشانگر این است که آموزش مدیریت رفتار به والدین درکاهش خشم نوجوانان قلدر، هردوگروه تاثیر مثبت داشته است. . نتایج درمرحله پیگیری نیز تفاوت معناداری (05/0 P< ) را بین گروه آزمایش وکنترل نشان داد. The results of the follow-up phase difference (P <0.05) between the test and control groups, respectively. Conclusion: The findings revealed that the behavioral management training had been effective in reducing anger bullying teenagers that might have been due to the effect of education on their daily relations. کلید واژه‌ها: آموزش مدیریت رفتار، بهزیستی روانشناختی، قلدری Keywords: Anger, Bulling, Behavior management training}, Keywords = {Anger, Bulling, Behavior management training}, volume = {21}, Number = {9}, pages = {900-913}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1508-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1508-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Haghighi, S and Movahedzadeh, B and Malekzadeh, M}, title = {The Effectiveness of Group Cognitive Hypnotherapy on Major Depression Referred to Residential and Semi-residential Addiction Recovery Centers}, abstract ={Background and aim: Psychological consequences of addiction, such as major depression regardless of physical problems, economic, cultural and social is cause problems for both families and society. The aim of this study was to evaluate the effectiveness of group cognitive hypnotherapy on major depression in residential and semi-residential addiction recovery centers in the city of Yasuj. Methods: The present quasi-experimental study was conducted using a pre-test, post-test and control group. The population included all patients drug dependent as residential and semi-residential referred to Yasuj addiction recovery centers. 40 patients were selected by convenience sampling and randomly assigned to experimental and control groups. The instrument used in this study included Beck Depression Inventory which depressed patients diagnosed and according to clinical interview they entered the study. Group cognitive Hypnotherapy intervention model was carried out on the experimental group for 8 sessions for one hour once a week, but there was no intervention on control group. After the intervention both experimental and control groups were assessed. Collected   data was analyzed using covariance analysis. Results: The results revealed that the cognitive hypnotherapy treatment of group, leading to depression reduced significantly in the experimental group compared control group significantly (p <0.001). The mean pre-test score of major depression in the experimental group and in control group was 39/5 ± 10/54 and 61/4 ± 20/52 respectively.  Whereas the mean and standard deviation of major depression and post-test scores in the experimental group 55/2 ± 05/25 and in the control group was 50/3 ± 55/51. Conclusion: Cognitive hypnotherapy can be used as adjunctive therapy in reducing major depression or used in addiction recovery centers.}, Keywords = {Addiction, Cognitive hypnotherapy, Major depression}, volume = {21}, Number = {9}, pages = {914-923}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1541-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1541-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Rashidi, H and Tafazoli, M and Jalali, MT}, title = {Relationship between Serum Lipids and Insulin Resistance among Women with Polycystic Ovary Syndrome}, abstract ={Background and aim:  Polycystic ovary syndrome is a common endocrine disorder that is associated with lipid disorders and obesity with an increased risk of cardiovascular disease. The aim of this study was to determine the association between lipid profile and fasting blood sugar levels and insulin resistance among women with polycystic ovary syndrome. Methods: The present case-control study was conducted on 153 women with PCOS and 449 healthy women as controls. Data was extracted from data center of Diabetes Research Center of Ahvaz University of Medical Sciences including women from 4 cities of Khuzestan province (Ahwaz, Behbahan, Abadan, and Khorramshahr). Serum lipids, fasting blood sugar, and serum insulin levels along with Body Mass Index (BMI), Homeostatic Model Assessment Insulin Resistance (HOMA IR), Lipid Accumulation Product (LAP), and Body Adiposity Index in two groups were analyzed by independent t-tests, chi-square and Fisher exact test. Results:  The frequency of low HDL and high total cholesterol was higher in women with PCOS than control group (p =0.032, and p =0.001, respectively). No significant difference was seen between No two groups in the mean levels of total cholesterol, triglyceride, HDL cholesterol, LDL cholesterol, fasting blood sugar, HOMA IR, LAP, and PA (p >0.05). In women with BMI<25 and BMI between 25 and 30, the mean level of total cholesterol was higher in PCOS group than control group, whereas there was no significant difference in women with BMI>30. In women with BMI>30, the mean triglyceride and glucose levels was higher in PCOS group than control group (p=0.029, and p=0.010). Conclusion:  In the present study, in obese women, triglyceride and fasting glucose levels were higher in patients with polycystic ovary syndrome than healthy women. In non-obese women, however, the total cholesterol level was higher in patients with polycystic ovary syndrome than healthy women.  }, Keywords = {Polycystic ovary syndrome, Lipid profile, Fasting plasma glucose, Insulin resistance, Obesity}, volume = {21}, Number = {9}, pages = {939-949}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1323-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1323-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2016} } @article{ author = {Shahinfar, J and Zeraati, H and Ghorbanzade, M and Vafaei, SH and Hashemi, F}, title = {Comparision effect of adequate intraoperative fluid therapy with dexamethasone on the incidence and severity of nausea and vomiting after general surgery}, abstract ={Abstract: Background and aim: Nausea and vomiting are one of the most common and unpleasant side effects of surgery and anesthesia, which causes spasms, aspiration, need more medicine. The researchers express several drugs and methods to reduce transmission of its complications. The aim of this study was to determine the effect of fluid therapy on nausea and vomiting after abdominal surgery. Methods: In this double blind clinical trial study, 120 patients 15-60 years undergoing general participated in Bojnurd. Patients were randomly divided into three groups. Group 1 received adequate intra-operative fluid therapy. Group 2 received pharmacological intervention with dexamethasone 0.1 mg per kg of body weight along with induction of anesthesia- and group 3 - without prophylactic intervention-. The research tools included demographic, visual analogue scale and recorded the number of vomiting. The visual analog scale was used to assess the severity of nausea. In order to assess the severity of vomiting, frequency count was considered as retch or vomit. The scientific validity of content validity was used for data collection. For reliability, the correlation coefficient was used. Based on self-reporting scale, the severity and incidence of nausea and vomiting were evaluated in three stages- post-op, 2 and 6 hours post-op - the data were analyzed with SPSS software. Results: Result showed that the three groups were homogeneous in terms of confounding variables. According one-way ANOVA, the difference between severity and incidence of nausea and vomiting was significantly different among the three groups in the recovery phase. So that based on post hoc test, the difference between the control and fluid therapy with dexamethasone group was significant, and both dexamethasone and fluid therapy had no significant differences in terms of these variables together. Based on the findings the incidence of vomiting was relatively low over time. Conclusion: Regarding the effect of adequate fluid resuscitation on nausea and vomiting after abdominal surgery, this procedure can reduce nausea and vomiting after surgery by low cost and less damage.}, Keywords = {Liquid adequate medical treatment, Dexamethasone, Nausea, Vomiting, Surgery}, volume = {21}, Number = {10}, pages = {950-963}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1465-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1465-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2017} } @article{ author = {Aghah, M and Daryanoosh, F and Moeini, M and Mohamadi, M and Fatahi, MR}, title = {The effect of 12 weeks vitamin E supplemention and aerobic training on liver enzymes of non-alcoholic steatohepatitis patients}, abstract ={Background and aim: Non-alcoholic steatohepatitis is a part of broad spectrum of chronic non-alcoholic fatty liver disease. The aim of present study was to evaluate the effect of 12 weeks vitamin E supplementation and aerobic training on liver enzymes level of non-alcoholic steatohepatitis patients (NASH).   Methods: In the present quasi-experimental study, 30 NASH patients, aged 25-50 years were participated, and divided into three groups of vitamin E (n=10), aerobic training (n=10) and combination (aerobic training plus vitamin E, n=10) randomly. Vitamin E Supplementation and aerobic training combination groups consumed 400 IU per day of Vitamin E Supplementation. Also in the group of aerobic exercise and combined, exercise program including the increasing activity of anaerobic (running on a treadmill with increasing intensity every two weeks 5%) was carried out three times a week for 12 weeks. Data evaluation were analyzed using t-test, ANOVA and Scheffe. Results: A significant differences was observed  ALT (intra-group) of vitamin E (0001/0 = p) aerobic exercise (0001/0 = p) and combination (001/0 = p), respectively.There was a significant difference was seen among pre – post training in AST in supplementation(P=0.001), aerobic training(P=0.001) and combination (P=0.002) groups. But no significant difference in ALP level observed(P>0.05). In comparison among the groups, a significant differences was observed between groups ALP vitamin E, combination aerobic exercise but no significant difference was observed among the groups at the levels of ALT and AST. Conclusion: The results of this study showed that vitamin E supplementation and aerobic training can improve non-alcoholic steatohepatitis Patients (NASH).  }, Keywords = {Vitamin E Supplementation, Aerobic training, Non-alcoholic steatohepatitis}, volume = {21}, Number = {10}, pages = {964-975}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1481-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1481-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2017} } @article{ author = {Zamanian, Z and Norouzi, F and Esfandiari, Z and Rahgosai, M and Hasan, F and Kohnavard, B}, title = {Assessment of the prevalence of musculoskeletal disorders in nurses}, abstract ={Abstract: Background and aim: Nursing staff are always at risk of work-related musculoskeletal disorders which is the most important health problems among nurses. This study aimed to assess the prevalence of musculoskeletal disorders in nursing personnel. Methods: This cross-sectional study was conducted in 2014. In this study, 200 nurses in teaching hospitals in Shiraz were selected by random cluster sampling.  The Nordic questionnaire was used for data collection. The data was analyzed using t tests and chi-square tests. Results: Results showed that 100 percent of the study population in the last 12 months, at least one organ of ​​the body's involved in musculoskeletal disorders. Most problems were related to the back (12.7), knees (12.6) and lower back (12.4). Significant relationship was observed between sex and the prevalence of musculoskeletal disorders of the neck. Moreover, a significant association was seen between age and prevalence of musculoskeletal disorders in the leg. Conclusions: Nurses have a high prevalence of musculoskeletal disorders and risk factors associated with the job is complex.}, Keywords = {Nordic questionnaires, Musculoskeletal disorders, Nurses}, volume = {21}, Number = {10}, pages = {976-986}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1157-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1157-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2017} } @article{ author = {Sodani, M and Mehdizadeh, A and Rajabi, G and KhojastehMehr, R}, title = {The effectiveness of group selection theory on the quality of drug addicted life}, abstract ={Backgrounds and aim: Increase in addiction in the community and the plight of its people demand for improving the problems of addicts, indicate a need for individuals to interventions and training expertise. The aim of this study was to investigate the effectiveness of group selection theory on the quality of drug addicted life.  .  Methods: This study is an quasi-experimental design with pretest-posttest and follow up with the control group. The study population included: all addicted people who referred to ahvaz addiction treatment center in 2015. 50 addicts were selected by using of  available sampling and randomly divided into  two experimental group (number=25) and control group (number=25). The participants were completed the quality of life inventory in three stages (pre-test, post-test and follow-up after 60 days). The experimental group was received group training of the concepts of selection theory of 10 sessions of 90 minutes per week.Statistical data were analyzed  using of covariance(ANCOVA) analysis. Results: Group training theory led to a significant difference among pretest, posttest, and follow-up of quality of addicted people life (p <0.001). In this case, the post-test and follow-up, after controlling of pre-test score, the experimental group compared to the control group higher quality of life was reported. Conclusion: Group training of selected theory about the role of choosing a behavior, five senses  the importance of self control, the role of effective behavior, the way of need fulfilment, responsibility, self worth, Quality world, seven destructive behavior, seven caring behavior, faiure identification and success identification can result in increasing the quality of life for addicted people.}, Keywords = {Concepts of Choice theory, Quality of Life, Addicts.}, volume = {21}, Number = {10}, pages = {987-998}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1240-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1240-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2017} } @article{ author = {Omidi, A and Sharifi, A}, title = {The Effect of Methanolic Extracts of Plants Quercus brantii, Pistacia atlantica and Elaeagnus angustifolia on Biofilm Formation of Pseudomonas aeruginosa}, abstract ={Abstract Background and aim:  Biofilm formation is one of the most notable mechanisms that contributes to antibiotic resistance in P.aeruginosa , The aim of this study was to determine the effects of methanol extrac of Quercus brantii,  Pistacia atlantica, Elaeagnus angustifolia Leaves  on biofilm formation P. aeruginosa strains. Methods: this study is an experimental study, that extraction with Maceration (powder mixed with 80% methanol) using rotary evaporator method. done. The minimum inhibitory concentration of extracts was determined by broth microdilution. Biofilm formation was investigated using the microtiter plate and stained with crystal violet. Collected data were analyzed using ANOVA and Duncan test. Results: The minimum inhibitory concentration of Quercus brantii, Pistacia atlantica, Elaeagnus angustifolia extracts against Pseudomonas aeruginosa was 0.625 mg/ml whereas, the Minimum bactericidal concentration of Quercus brantii jaft was 1.25 mg/ml and for Pistacia atlantica and Elaeagnus angustifolia were 2.5 mg/ml. The mean percentage of of Pseudomonas aeruginosa biofilm inhibition by extracts of Quercus brantii (jaft), Pistacia atlantica, Elaeagnus angustifolia were 60.24, 57.35, and 72.63 % respectively. Conclusion: Methanolic extracts of medicinal plants Quercus brantii, Pistacia atlantica, Elaeagnus angustifolia has anti-bacterial and anti-biofilm effect against Pseudomonas aeruginosa. So that Elaeagnus angustifolia extract had a capability to inhibit biofilm formation and also showed a significant difference compare to Quercus brantii jaft, Pistacia atlantica extract. With further study it can be used of  these extracts as a supplement to inhibit bacterial biofilm.}, Keywords = {Pseudomonas aeruginosa, biofilm, Quercus brantii, Pistacia atlantica, Elaeagnus angustifolia}, volume = {21}, Number = {10}, pages = {999-1012}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1549-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1549-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2017} } @article{ author = {JaliliNikoo, S and karimi, Z and Nejatinejad, N and Bahmani, B and Naghiaee, M and GhasemiJobaneh, R}, title = {Effectiveness of cognitive Existential Group therapy on quality of life of elderly people}, abstract ={Abstract Background and aim: With an aging population, considering the factors affecting the quality of life more than ever is necessary. The aim of current research was to investigate the effectiveness of cognitive existential therapy on quality of life of elderly people. Methods: The current research is semi experimental with pre and post test with control group. Statistical population of research consists of all elderly people in Kahrizak nursing homes. In the first phase, the participants were selected through purposive sampling method and after responding to the quality of life questionnaire and obtaining score for enter to research they were divided in two groups of experimental and control (N = 12 per group) using random sampling method.  The experimental group participated in 10 sessions of group counseling based on cognitive- existential approach and control group received no intervention. The gathered data were analyzed using covariance analysis. Results: There was no difference between pre-test and control groups, but the mean scores of post-test experimental and control groups were statistically significant. and cognitive group therapy improves quality of life is (p=0.001). Therefore it seems that cognitive-existential group therapy increase quality of life of elderly people. Conclusion: Cognitive Existential Group therapy utilizes concepts such as death, meaning, cognitive distortions and responsibility could increase the level ofquality of life of elderly people. Thus interventions based on this approach could be useful in improving the quality of life.}, Keywords = { Group therapy, Cognitive Existential, Quality of life, Elderly}, volume = {21}, Number = {10}, pages = {1013-1021}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1341-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1341-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2017} } @article{ author = {Ghadei, R and Eilami, O and Jahanbin, Sh and Aghaee, S and Hossini, M and Jokar, S}, title = {A Case Report: Liver Abscess Caused by Fasciola hepatica in Yasuj}, abstract ={Abstract Background and aim: Liver abscesses are the most common type of visceral abscess. The rare cases of liver abscess caused by F. hepatica infection has been reported. F. hepatica is Liver trematode common to humans and animals. F. hepatica have global emission and common in temperate, hot and humid zones especially in areas where livestock farming is common. The aim of this article is to report a case of liver abscess which was infected with F. hepatica. Case Report: This Report is related to patient who initially diagnosed with liver abscess and taken medication for liver abscess, with no properly treated and refer by relapsing fever. After radiological studies and positive serology for F. hepatica the patient was undergo the treatment of fascioliasis and liver absecess. following the treatment the fever and liver lesion waer disappeared .  Reports of patients who initially diagnosed with liver abscess antibiotic treatment was that the abscess was not properly treated Result: Given that, the new focus on F. hepatica infection which have been reported in southern Iran, in the all cases with fever and liver abscess in this geographic areas, F. hepatica considered in the differential diagnosis.}, Keywords = {Liver abscess, Relapsing fever, Fasciola hepatica}, volume = {21}, Number = {10}, pages = {1022-1028}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1496-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1496-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2017} } @article{ author = {Nazaripour, AH and Mosavi, SNJ and Hakak, M and Pirzad, A}, title = {Explanation of model design and talent management system in universities}, abstract ={Abstract Background and aim: Nowadays talented human resources are considerd as the most important and valuable organizational asset. Proper management of these major asset, the the most essential task manager and the progress of any organization in this field is fierce competition with competitor. The aim of this study was to develop a model system for talent management in universities in the country. Methods: In this study the population was composed of 10 Azad Universities university faculty members include of specialists and human resource managers at the national level the country. Data were collected from questionnaires that approved by Cronbach's alpha reliability was used.   Interpretive Structural Equation Modeling were applied for interactive display input and output elements. Input and output components of the talent management system to help Grounded theory and literature were identified. The data were analyzed by t-test and Vlnykaksvn. Results: The results showed that talent management can lead to individual and organizational elevation, as the highest level of academic performance. The research findings indicate that the results or outputs of individual talent management, are prior to the organizational results.  Conclussion: Based on the findings and outcomes obtained, it is recommended to university authorities to identify talent, develop their talents and try their best to maintain their dominant reality.}, Keywords = {Systemic model, Talent management, Structural interpretive modelling}, volume = {21}, Number = {10}, pages = {1029-1040}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1516-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1516-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2017} } @article{ author = {Ghasemi, SH and AbtahiFroushani, SM and Ownagh, A}, title = {The effects of hydro- alcoholic extract of Hypericum perforatum on cell migration and inflammatory mediators production in acute peritonitis induced by Zymosan in NMRI mice}, abstract ={Background and aim: Zymosan-induced peritonitis model can use to study the recruitment of monocytes and neutrophils into the peritoneal cavity and to study the effects of existing and novel anti-inflammatory drugs. This study was conducted to evaluate the effects of hydroalcoholic extract of Hypericum Perforatum on acute peritonitis induced by Zymosan in NMRI mice. Methods: Fifty male NMRI mice were randomly allocated in 10 equal gropes and treated with 0 ,100, 200 or 400 mg/kg of hydroalcoholic extract of H. Perforatum and or 10mg/kg diclofenac 1 hours before the induction of peritonitis. To induce peritonitis, each mouse intraperitoneally received 10 µg of zymosan in 0.4 ml of saline. After 48 h, the peritoneal cavity was lavaged by 5 ml of cold PBS and the isolated cells were used  to evaluate cell differential count, nitric oxide production and severity of respiratory burst. Statistical dada tests were analyzed using the Kruskal-Wallis test, Mann-Whitney and Bonferroni adjustment. Results: The data showed that the nitric oxide and respiratory burst which was produced from exudate cells by  peritoneal lavage in mice that received H. Perforatum at  doses of 200 and 400 mg/kg or diclofenac compared to mice received normal saline were reduced. Total cell number in peritoneal cavity significantly decreased in all treatment group. However, no significant difference was observed between treatment groups with Hypericum perforatum extract. Using diclofenac or hydroalcoholic extract of H. Perforatum caused a significant decrease in the levels of TNF-α, IL-1 and IL-6. Diclofenac caused more profound reduction in the levels of TNF-α, IL-1 compared to extract. Nevertheless, the level of IL-6 was indicated a significant decrease in mice with peritonitis received hydroalcoholic extract especially in dose 400 mg/kg compared to mice with peritonitis received diclofenac. Conclusion: In total it seems that the hydroalcholic extract of H. Perforatum may be a suitable as natural source to control inflammation caused by acute peritonitis.}, Keywords = { Peritonitis, Zymosan, Hypericum perforatum}, volume = {21}, Number = {11}, pages = {1041-1055}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1558-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1558-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2017} } @article{ author = {SadeghpourNatanzi, M and Parsania, M and Aminzadeh, M}, title = {Antiviral and virucidal activity of Chelidonium majus L. extract compared with Acyclovir against Herpes simplex virus type 1}, abstract ={Background and aim: Herpes simplex virus is one of the most important human pathogenic viruses that may lead to oral herpes, keratoconjunctivitis and even encephalitis. A number of enzymes of the virus such as DNA polymerase can be targeted antiviral drugs. Acyclovir is used to treat infections of the virus, today due to drug resistance, need to do more research on finding new drugs, especially herbal medicines has increased. This study aimed to investigate the antiviral effect of methanol extract of Chelidonium majus compared with acyclovir against the virus in HeLa cell culture. Methods: In this experimental study, the toxicity of Chelidonium majus L. methanol extract and acyclovir on HeLa cell was determined with both MTT and Trypan blue methods. The antiviral effect of Chelidonium majus L. extract and acyclovir was evaluated in different concentration (1800- 1700- 1600- 1500- 1400 and 500- 100- 75- 50- 30-10 µg/ml) and also in different times before, after and during of virus adsorption respectively.  The virus titer was measured by tissue culture infectious dose 50 )TCID50(  method. The T-test method was used to comparing the effects of both compounds on virus. Results: The maximum non-toxic concentration of Chelidonium majus L. extract on HeLa cell was determined 1600 µg/ml that has the maximum inhibitory effect on HSV-1 replication. Acyclovir was shown low toxicity on HeLa cells.The 30 µg/ml concentration of acyclovir was considered for the next steps of the study.The highest inhibitory effect of the extract was observed 1 hour after absorption and the virus replication was suppressed completely by the acyclovir immediately after virus adsorption up to 8 hours after infection. Conclusion: The Chelidonium majus L. methanol extract has less effect than the acyclovir on inhibition of herpes simplex virus replication in a first few hours of infection. More research is needed to achieve effective compounds with antiviral activity of above extract due to increasing acyclovir resistant strains also its side effects.}, Keywords = {Chelidonium majus L. , Acyclovir, Herpes Simplex Virus Type 1, HeLa Cell, Antiviral effect}, volume = {21}, Number = {11}, pages = {1056-1068}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1556-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1556-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2017} } @article{ author = {Mohammadi, M and SheykhHadiSiruii, R and Garafar, A and Zahrakar, K and Shakarami, M and Davarniya, R}, title = {Effect of Group Cognitive Behavioral Couples Therapy on Couple Burnout and Divorce Tendency in Couples}, abstract ={Background & aim: Couple burnout is one of the phenomena which involve many couples, it is among the main causes of emotional divorce, and without proper management and treatment, and it can lay the ground for formal divorce among couples. Cognitive behavioral couple therapy is one of the existing approaches in the couple therapy field, the efficiency of which has been established for resolving many marital problems. The present study was designed by the aim of investigating the effect of group cognitive behavioral couple therapy on couple burnout and divorce tendency in couples.   Methods: The present research was of applied research type. The research method was semi-empirical with a pretest-posttest with control group design. The research population included all the couples with marital conflict and problems who, after a recall announcement of the researcher, visited the counseling and psychological services center located in Gorgan city in 2014. By using the available sampling method, 20 couples were selected among the volunteer and qualified couples for the research, and they were assigned into experiment and control groups (10 couples per group) by random assignment. In the present research, the Pines burnout questionnaire (1996) and divorce tendency scale of Rouswelt, Johnson, and Mouro (1986) were used for gathering the data. After taking the pretest, the group cognitive behavioral couple therapy based on the couple therapy model of Baucom  and colleagues (2008) was held in 10 2-hour weekly sessions for the experiment group couples, while the control group couples received no intervention. The data were analyzed through descriptive statistics method and multivariate covariance analysis (MANCOVA) in SPSS v.20. Results: The multivariate covariance analysis results for couple burnout (F= 28.80) and divorce tendency (F= 51.25) suggested that there was a significant difference between the couples of experiment and control groups (P< 0.01). According to the posttest scores of the experiment control groups for these two variables, it was recognized that the cognitive behavioral couple therapy has led to reduction in couple burnout and divorce tendency among the couples of the experiment group in comparison to the control group in the posttest stage.    Conclusion: The research findings indicate that the cognitive behavioral couple therapy model can reduce marital problems, and using this couple therapy approach is recommended for working with the couples involved in marital problems with divorce demand.  }, Keywords = { Cognitive behavioral couple therapy, Couple burnout, Divorce tendency, Couples}, volume = {21}, Number = {11}, pages = {1069-1086}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1404-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1404-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2017} } @article{ author = {Shabani, T and Hosseini, SE}, title = {Comparison of the Hydro-Alcoholic Extract of Ginseng Root with Metformin in Rats with Polycystic Ovary Syndrome}, abstract ={Background & aim: Polycystic ovary PCOS is considered as the most common cause of infertility in women. Due to the side-effects of chemical drugs such as metformin, which is used to treat this disorder, the purpose of this paper was to study the effect of metformin with Ginseng root in this disease treatment.  Methods: In the present experimental study, 50 adult female rats were divided into 5 groups: control, sham PCOS (treated with letrozole) and three experimental groups receiving metformin (500mg/kg), ginseng extracts (500mg/kg) and metformin with Ginseng. All administrations were done as gavage for 28 days. Then, blood samples were taken to measure FSH, LH, estradiol, progesterone and testosterone hormones in animals, follicle ovaries were removed and the tissue sections were counted. The collected data were analyzed via ANOVA and Duncan tests. Results: The results indicated that letrozole caused a significant increase in the serum level of testosterone, LH, cystic follicles number and the animals’ weight but a significant decrease in estrogen, progesterone and ovarian follicles were seen in comparison with the control group (p≤0.001). But, in rats treated with letrozole, administration of metformin and Ginseng alone and together caused to prevent the effects of this drug on serum level of estrogen, progesterone, testosterone, LH, and cystic-ovarian follicles. No significant difference between the effects of metformin and ginseng was observed.  Conclusion: By making PCOS Letrozole causes increase in weight gain, testosterone, LH and cystic follicles and a decrease in ovarian follicles and ginseng, but metformin and ginseng alone and together prevent the effects of this drug.}, Keywords = {PCOS, Letrozole, Metformin, Ginseng extracts,Rat}, volume = {21}, Number = {11}, pages = {1087-1099}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1379-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1379-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2017} } @article{ author = {Ghadampour, E and Radmehr, P and Yousefvand, L}, title = {The effectiveness of acceptance and commitment based treatment on social competence and life expectancy of patients with multiple sclerosis}, abstract ={Background & aim: Multiple Sclerosis is a neurological disability disorders, which creates many physical and mental differences. The aim of the study was to evaluate the effect of acceptance and commitment therapy on social competence and life expectancy of patients with multiple sclerosis.  Methods: The present study design was experimental with pre-test, post-test and follow-up and control group. Statistical population of this study consisted of all female patients admitted to the multiple sclerosis (MS) society of Kermanshah cityt to purpose of implement a screening test. At the begening a number of 220 people completed the Felner-social competence and Miler-life expectancy questionnaires. Among them the 30 persons through purposeful sampling that in the abnormal situation (on standard deviation lower group average) were selected. Then the selected 30 persons were randomly divided into two equal groups of experimental and control. In the experimental group the acceptance and commitment therapy were conducted for 8 sessions 90 minutes. After completing the session, post-test and three months after the intervention, follow-up was conducted on two groups. Analyzed of the data was done using spss19, descriptive test (mean and Standard deviation), and ANOVA with repeated measure. Results: Repeated measures analysis of variance showed that acceptance and commitment therapy based on increasing social competence and life expectancy of patients with multiple sclerosis had significant effect. Findings were also preserved in the follow-up phase. Conclusion: According to the effect of acceptance and commitment therapy on increase social competence and life expectancy suffering and its effects, application of this method at all levels of prevention and treatment of physical illness among multiple sclerosis seems necessary.}, Keywords = {Acceptance and Commitment, Social Competence, Life Expectancy, Multiple Sclerosis}, volume = {21}, Number = {11}, pages = {1100-1114}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1444-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1444-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2017} } @article{ author = {Zarei, M and Fazlara, A and Zarezadeh, F}, title = {Evaluation of the Histamine Content and Potential Toxicity of Some of Consumable food}, abstract ={ABSTRACT Background & aim: Consuming high amounts of histamine with food causes histamine poisoning among its consumers. Much information about the content of histamine in various food products is not available in the country. In the present study, the amount of histamine in food samples consumed in human diet which are based on existing data sources can contain histamine were measured. Methods: In the present study, 240 samples of 16 different types of food consumed in the human diet were examined. Histamine was extracted with 75 % ethanol- 0.4 N HCl in fresh and canned fish samples and extracted in other samples with  0.1 N HCl. After passing the extracts through ion exchange chromatography, the fluorescence derivative of histamine which was generated by O-phthaldialdehyde and the amount of fluorescent light was measured at excitation wavelength of 350 nm and emission wavelength of 444 nm respectively. Data were analyzed using descriptive statistics. Results: Spinach, fresh fish, canned fish and aubergine samples showed the high level of histamine with the mean levels of 5.04, 3.83, 2.77 and 2.64 mg/100g respectively. All samples tested contains histamine but 53.3, 20.0, 13.3 and 13.3 percent of the samples of these foods contains higher amounts histamine (5mg/100gr)  respectively.Low levels of histamine was observed in a number of samples including tomato, pickles, nuts, bananas, oranges, melons, cheese, curd, yogurt and dough but no detectable histamine was found  olive and tea. Conclusion: In addition to confirming the fact that fish and seafood products have a high risk of histamine poisoning, but it showed that the risk of histamine poisoning in humans after consumption of fish and its products will not be less than spinach and aubergine.}, Keywords = { Histamine, Spinach, Fish, Canned fish, aubergine}, volume = {21}, Number = {11}, pages = {1115-1124}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1231-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1231-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2017} } @article{ author = {Saberi, Z and Banitalebi, E and Faramarzi, M}, title = {The Combined Effects of Training on Serum Levels of Interferon Gamma (INF-γ) and Expanded Scale Disability Status Scale of Patients with Multiple Sclerosis at Different Levels of Disability}, abstract ={Background and aim: Multiple sclerosis is a chronic and debilitating nervous system, leading to demyelination of the central nervous system (brain and spinal cord). Regular exercise and general physical activity is important to maintain health and prevent disease, already well known. Therefore the aim of this study was to evaluate the effect of 12 weeks of combined exercises (strength training, Strengthening Exercises, cardio respiratory endurance, a variety of static and dynamic balance exercises, exercises of the trunk (pilates training) and walking on the treadmill training with body weight support) on interferon gamma and Expanded Disability Status Scale women with multiple sclerosis. Methods: In the present experimental rsearch, female patients who were admitted to the MS Society of Shahrekord, Iran, were divided into three groups based on physical disability scores. In the first group (physical disability scale less than 4.5), 44 people were randomly selected to one experimental group (22 patients) and control group (n = 22). In the second group (scale physical disability between 5 and 5.6), 26 patients were enrolled and randomly assigned to an experimental group (n = 13) and control group (n = 13). The third (Physical Disability Scale-up to 6.5), 26 patients were enrolled and randomly assigned to an experimental group (n = 13) and control group (n = 13). A total of 96 patients were participated in this study. Experimental groups of first, second and third were done its own intervention separately. While the control group received stretching exercises, workout schedule for the experimental group was of 12 weeks, three sessions of lasted one hour. Anthropometric factors and interferon-gamma were measured before and after training with the appropriate tools. Serum levels of INF-γ was determind using a commercial ELISA kit and EDSS scores were measured using the measure of disability in patients with MS. Data analysis was performed using descriptive statistics and ANOVA and paired t-test and dependent. Results: The results showed that no significant differences were seen in the INF-γ subjects with low disability before and after exercise in the intervention group (p=1.017), whereas, there was no significant difference in the control group (p=0.229). In comparison, no significant difference was observed between intervention and control groups in terms of INF-γ (09/0 = p). The results indicated that significant differences INF-γ subjects with low disability before and after exercise was observed in the intervention group (p=0.309 Conclusion: Although combinated exercise training did not change on serum levels of IFN, but it casued asignificant changes in EDSS of the patients with M.S at different levels Regarding these results, it can be suggested that rehabilitation specialists use of these exercises as a complementary treatment along with drug therapy for MS patients.  }, Keywords = { Multiple Sclerosis, Anthropometric Characteristics, Combinated Exercise Training, Expanded Disability Status Scale}, volume = {21}, Number = {11}, pages = {1125-1141}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1545-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1545-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2017} } @article{ author = {Lotfian, N and TalaeiBajestani, A and RahmaniBeilondi, MR and Daiemi, M and RahmaniBeilondi, R}, title = {Ovarian Ectopic Pregnancy: a Rare Case Report}, abstract ={Background and aim: Ovarian pregnancy is an uncommon form of ectopic pregnancy which usually diagnosed so late. The aim of this study is to report a case of ovarian ectopic pregnancy Case presentation: A 19 years old woman, with a history of polycystic ovary, first pregnancy, gestation age 9 weeks and 4 days, visited the doctor. She was complaining of severe abdomen pain and vaginal spotting and she was bedridden because of threatened miscarriage. She had discharged from hospital with progesterone suppository prescription. Requesting a transvaginal ultrasound and heterogeneous echogenic mass (size18×8/5) was shown near the left ovary. It was shown as ectopic pregnancy. The patient was hospitalized by ectopic pregnancy in ovary diagnosis and she was treated by methotrexate. Conclusion: In pregnant women that complain of bleeding and spotting in early pregnancy, in addition to threatened abortion, ectopic pregnancy should exist even in the absence of clinical symptoms, should be considered.}, Keywords = { Ectopic pregnancy, Ovarian pregnancy, Abortion.}, volume = {21}, Number = {11}, pages = {1142-1148}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1574-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1574-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2017} } @article{ author = {SedaghatKH, KH and Parandin, R and Behnam-RassouliM, M and Mahdavi-Shahri, N and Kheirabadi, M and Kalkali, H}, title = {The Effects of Neonatal Administration of Tamoxifen and Zearalenone on the Features of Uterus Tissue in Mice}, abstract ={  Abstract Background and aim: The uterus as the major female reproductive organ is particularly vulnerable to environmental and hormonal like compounds. Exposure to estrogen like disrupting chemicals during critical periods of development especially in the neonatal period can have adverse effects on reproduction and fertility later in life. In the present study, the effects of neonatal exposure of mycoestrogen zearalenone and anti-estrogen tamoxifen on some histological characteristics of the uterus in female mice were investigated. Methods: 28 newborn female mice of BALB/c strain were divided into four groups of 7, three experimental and one control group. Treatment Groups included Tamoxifen (400 μg /kg /day) group, group treated with zearalenone (2 mg /kg /day) and group treated with tamoxifen                            + zearalenone. Control mice received no treatment. Daily treatments was started first day of life and continued up to 5 subcutaneously. Approximately, 70 days after birth in diestrous stage of estrous cycle, mice were deeply anesthetized and uterus was removed. Following histochemical staining, the samples were studied using light and transmission electron microcopies. Results: The result of this study indicated that among the treatment groups, body weight decreased significantly (P>0.05) in the group which received Tamoxifen compared with control group. Uterus weight increased significantly in Zearalenone group (P>0.05), Tamoxifen and Zearalenone group (P>0.01).  Endometrial thickness increased significantly (P>0.05) in group which received Tamoxifen and decreased significantly (P>0.05) in group which received Zearalenone. In addition, myometrial thickness decreased significantly (P>0.05) in group which received Zearalenone compared with control group. The study of electron microscopy showed that the number of cells of uterine luminal epithelial structure increased in the group treated with Tamoxifen compared with control group. Conclusion: The result of study indicated that neonatal administration of Tamoxifen and Zearalenone compounds cause histological lesions in uterus structure. Because of the estrogenic nature of zearalenone, the treated neonatal mice with this mycotoxin cause structural abnormalities especially in myometrial structure. On the other hand, Tamoxifen as an estrogenic agonist cause endometrial thickness increase and alterations in the uterus.  }, Keywords = {Zearalenone,Tamoxifen, Uterus, Mice, Estrogen}, volume = {21}, Number = {12}, pages = {1149-1163}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1401-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1401-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2017} } @article{ author = {Hasanvand, B and Soori, R and RastegarMoghadamMansouri, M and Abbasian, S}, title = {The effect of High Intensity Interval Training on Gene Expression of Inflammatory Biomarkers in Fast- and Slow muscles of Rats}, abstract ={Abstract   Background and aims: Lipocalin-2 (LCN-2) with Interleukin1-β (IL1-β) are inflammatory proteins that induced the inflammatory reactions due to insufficient of physical activity. The aim of the present study was to determine the effect of high intensity interval training on Lipocalin-2 and Interleukin1-β gene expressions in fast- and slow muscles of rats.   Methods: In the present study, 20 Wistar rats were divided into HIIT and control groups. HIIT protocol was performed 60 min in each session for four sessions in each week. After warm-up, HIIT group was carried out 15 × 4 min bouts of HIIT with 85 to 90% of VO2max that continued with three min recovery (between each bout of HIIT) with 70% of VO2max. LCN-2 and IL1-β and their gene translations were evaluated by commercial kits and Real-Time PCR method, respectively.      Results: Findings shown that VO2max was significantly increased and serum levels of LCN-2 and IL1-β were significantly decreased (p<0.05). Also, LCN-2 and IL1-β gene translations in both fast- and slow muscles were significantly decreased (p<0.05).     Conclusion: It seems that, current HIIT protocol has capability to significantly decrease both muscular and serum levels of inflammatory biomarkers such as LCN-2 and IL1-β in male rats. Particularly, results of current study shown that LCN-2 and IL1-β decreases are greater in EDL muscles.               }, Keywords = {Gene expression, Inflammatory Biomarkers, Lipocalin-2}, volume = {21}, Number = {12}, pages = {1164-1178}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1606-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1606-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2017} } @article{ author = {Aghamohammadi, M and Habibi, AH and Ranjbar, RA}, title = {The Effects of Aerobic Training on Serum Levels of Nitric Oxide, Pulmonary Function Parameters and Quality of Sleep in Women with Type 2 Diabetes}, abstract ={Abstract: Background and aim: Lack of physical activity increases the risk of cardiovascular disease, diabetes, pulmonary function and sleep quality, but with regular physical activity, may reduce many of these risk factors. The aim of this study was to find the effects of aerobic training on serum levels of nitric oxide, pulmonary function parameters and quality of sleep in women with type 2 diabetes.   Methods: In the present quasi-experimental study, 20 type 2diabetic women were selected and randomly assigned into two exercise (n = 12) and control (n = 8) groups. Aerobic training program was performed for six weeks (4 times a week, with 50% to 80% heart rate reserve) who receive the time and intensity of exercise (50 to 80 HRR) was added. Main aerobic exercises presented in the form of 6 chain, each chain includes 32 motion. FVC, FEV1 Indices and nitric oxide levels were measured before and after the intervention and Pittsburgh Sleep Quality Index questionnaires were used to assess sleep quality. Statistical analysis were analyzed using t-test, analysis of covariance and correlation coefficient.   Results: Six weeks of aerobic exercise indicated a significant reduction in sleep quality scores and but a significant increase in the concentration of nitric oxide and lung volumes (FVC and FEV1) compared to the control group (p≤ 0.05), but no significant relationship between lung volumes and a score of sleep quality was observed.   Conclusion: It seems that aerobic exercise training can have a considerable impact on serum nitric oxide pulmonary functions and thereby improve the sleep quality in patients with type 2 diabetes.    }, Keywords = {Type 2 diabetes, Aerobic training, Pulmonary function, Sleep quality, Nitric oxide}, volume = {21}, Number = {12}, pages = {1179-1191}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1336-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1336-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2017} } @article{ author = {AliAsgari, E and Mirzaie, A and Noorbazargan, H and BagheriKashtali, A}, title = {Cytotoxicity Effect of Lactobacillus casei Cell Extract as Indigenous Probiotic Bacterium on Colon Cancer Cell Line (HT29) and Analysis of Bax and Bcl2 Apoptosis Gene Expression}, abstract ={Abstract Background and aim: Nowadays, the probiotic bacteria such as lactobacilli are known as preventing factors the development of many diseases including cancer. The aim of this study was to investigate the cytotoxic effect of Lactobacillus casei PTCC 1608 cell extract as probiotic bacteria on colon cancer cell line (HT29) and analysis of Bax and Bcl2 apoptosis gene expression.   Methods: In this experimental study, the cell extract of heat killed L. casei was prepared at 0.01, 0.1, 1, 10, 100 and 1000 µg/ml concentration. The cytotoxicity of various cell extracts on HT29 and HEC293 cell lines were evaluated in 24 hours using MTT assay. Moreover, the Bax and Bcl2 apoptosis gene expression level in HT29 cell line was analyzed using Real Time PCR. The apoptotic effects of cell extract was determined using Flow-cytometry technique. Finally, the collected data were statistically analyzed using one-way anal­ysis of variance with the SPSS/18 software.   Results: The results of MTT assay showed that cell extracts of L. casei was able to reduce the survival rate of HT29 cell line to 0.95±0.44, 73.45±0.21, 51.49±0.87, 39.5±0.45 and 19.7±0.55. Also at the same concentrations in HEC293 cell lines resulted in survival decreased rate of 98.67±056, 94.31±0.87, 26/0 ± 1/92.1±0.26, 91/89.91±0.42, 34/8434±0.55, 29/79.29±0.49.  In addition to the Real Time PCR results the expression level of Bax and Bcl2 was increased and decreased in HT29 cell line respectively (2.76 ± 0.54 (P<0.05), 0.21 ± 0.43 (P< 0.05)) in 24 hrs. Moreover, the flow cytometry results indicated the 35.62 % apoptosis in HT29 cell line treated with IC50 value.   Conclusion: The results show that the cell extract of L. casei PTCC 1608 could induced the apoptosis in HT29 cell line and it had low toxicity on HEC293 cell line. Therefore, it seems that L. casei has potential uses as probiotic for pharmaceutical applications including prevention and treatment of colon cancer.    }, Keywords = { Lactobacillus casei, Probiotic, HT29 cell line, Cytotoxicity, Apoptosis}, volume = {21}, Number = {12}, pages = {1192-1206}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1673-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1673-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2017} } @article{ author = {Ansari, H and Doosti, A and Kargar, M and Bizhanzadeh, M and Jafarinya, M}, title = {Cloning and Sequencing of the ompA and smpA Virulence Genes of Acentobacter baumannii Isolated in Clinical Samples}, abstract ={Abstract Background and aim: Acinetobacter baumannii is one of the emerging and important pathogens in various infections such as urinary tract infection, hospitals, meningitis and respiratory tract. The aim of this research is cloning and sequencing of ompA and smpA virulence genes of A. baumannii.   Methods: In this experimental study, the pathogenic A. baumannii was cultured on blood agar and macconkey agar mediums. Recognition of A. baumannii with microscopic, microbiologic and biochemical tests were performed. ompA and smpA genes were amplified by PCR and then cloned into the pTZ57R/T vector. The accuracy of the recombinant construct was carried out with PCR and enzymatic double digestion and then the both of ompA and smpA genes were sequenced. The evaluation of bacterial expression of these genes was performed with SDS-PSGE method in E. coli.   Result: The pathogenic A. baumannii was confirmed in biochemical and microbiological methods. After electrophoresis of the PCR products, the 1150 and 411 bp fragments of ompA and smpA genes were obtained, respectively. The results of PCR and double digestions on recombinant plasmids showed that the pTZ57R/T-ompA and pTZ57R/T-smpA were generated. The sequencing results confirmed the accuracy of the gene cloning.   Conclusion: The results showed that the pTZ57R/T is a suitable vector for the cloning of large fragment of PCR products and ompA and smpA are two highly conserved genes that appropriate for use as DNA vaccine.  }, Keywords = { Acinetobacter baumannii, Cloning, ompA, smpA, Sequencing }, volume = {21}, Number = {12}, pages = {1207-1217}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1546-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1546-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2017} } @article{ author = {Sobhani, Z and Ahadi, H and Khosravi, S and Pourshrifi, H and Seirafi, M}, title = {The Effectiveness of Motivational Interviewing on Adherence in Obese Patients Undergoing Sleeve Gastrectomy Surgery}, abstract ={Abstract   Background & aim: Adherence is the degree of patient's success to do the health experts recommendations. The aim of present research was to study the effects of motivational interviewing on adherence to in obese patients undergoing sleeve gastrectomy surgery.   Methods: The design of present semi- experimental study was pre-test, post-test with control group. The statistical population included all obese patients (BMI≥35) that undergone laparoscopic sleeve gastrectomy surgery in Shiraz Ghadir Mother & Child Hospital during the winter of 2015 and the spring of 2016. 30 of them were selected by using available sampling method and they randomly were asssigned to experimental (n=15) and control groups (n=15). The post bariatic surgery self-management behaviors questionnaire was used to collect data in two steps (pre-test and post-test). Motivational interviewing was implemented for the experimental group in four weeks (each week a 1.5 hour session). Data were analysed by using multivariate covariance analysis (MANCOVA).   Results: MANCOVA results show that motivational interviewing led to a statistically significant difference between pre-test and post-test BSSQ total scores (P<0.0001) and subscales eating behaviors (P<0.0001), fluid intake (P<0.03), vitamin and mineral supplement intake (P<0.01), fruit, vegitable, whole grain intake and protein (P<0/01) & dumping syndrome management (P<0.002). But there was no significant difference in the score of physical activity (P>0.07).   Conclusion: According to the results of the present study, implementation of motivational interviewing in order to enhance adherence and self-management behaviors, achieve favorable weight loss and reduce postoperative complications in obese patients undergoing sleeve gastrectomy surgery, but it appears that longer interventions are necessary to increase the rate of physical activity.    }, Keywords = { Motivational Interviewing, Adherence, Obese Patients, Sleeve Gastrectomy Surgery }, volume = {21}, Number = {12}, pages = {1218-1235}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1567-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1567-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2017} } @article{ author = {Asadpour, L and Veisi, S}, title = {Mutations in grlA and norA Genes of Clinical Isolates of Staphylococcus aureus Resistant to Fluoroquinolone}, abstract ={Abstract   Background and aim: Fluoroquinolones are group of antibiotics that are commonly used as broad-spectrum and resistance to them is expanding. The mechanisms of resistance to fluoroquinolones in S. aureus is important in mutation a subunit of topoisomerase type II grlA and efflux pump. This study was aimed was to investigate mutations in grlA and norA genes of clinical isolates of S. aureus resistant to fluoroquinolones   Methods: In the present cross-sectional study, 85 S. aureus isolates from different clinical samples using culture and molecular methods were identified. The resistant of these isolates to fluoroquinolones was determined by disc diffusion method and MIC ciprofloxacin method was tested by macro dilution broth. To examine the relationship between infection and the position of each drug resistance status the chi-square test was used. A P value of < 0.05 was considered statistically significant.  Mutations in the quinolone resistance-determining regions (QRDR) in chromosomal grlA gene and norA gen mutations was investigated in quinolone-resistant S. aureus isolates, by PCR amplification of grlA and norA genes and sequencing. Results: In this study, 20% of isolates were resistant to all antibiotics fluoroquinolones studied. Using statistical analysis revealed no significant differences between fluoroquinolone resistance in isolates of S. aureus infection in patients and location was observed. MIC ciprofloxacin resistant isolates to fluoroquinolones was ranged between 32-512 mg/ml.   Two single mutations S80F and S80F and a pattern of P144S+ P144S in the grlA gene of fluoroquinolone resistant strains of S. aureus were identified, but no mutations were found in genes norA resistant strains. Also, no relationship between MIC of ciprofloxacin in resistant isolates and mutation in grlA was seen. Conclusion: The obtained results demonstrated that grlA gene mutation is one of the most important mechanisms of resistance to ciprofloxacin in clinical isolates of S. aureus in Rasht and most of resistant isolates acquired common mutation in codon 80.    }, Keywords = {Fluoroquinolone, S. aureus, grlA, norA}, volume = {21}, Number = {12}, pages = {1236-1246}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1607-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1607-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2017} } @article{ author = {RahmaniBeilondi, M and RahmaniBeilondi, R and Aryamanesh, H}, title = {Unilateral Twin Ectopic Pregnancy: A case report}, abstract ={Abstract   Aim & Objective: Twin ectopic pregnancy is very rare and in most cases occurs due to the use of assisted reproductive treatments. This study reports a case of twin ectopic pregnancy and spontaneous one-way deals.   Patient presentation: Investigated woman was 28 years old with third pregnancy and abortion recored have a healthy child of five years, with bleeding due to threatened abortion, despite treatment with progesterone. Following ultrasound, ectopic pregnancy twin confirmed eight weeks and finally due to signs of uterine rupture, the mother was undergone salpingectomy.   Conclusion: The study reports a case of ectopic pregnancy, spontaneous unilateral twins, who had been threatened abortion treats incorrectly, Therefore, in pregnant women with bleeding in early pregnancy are the common complaints, it is necessary to treat threatened abortion, ectopic pregnancy diagnosis should be considered.    }, Keywords = {Twin Pregnancy, Spontaneous, Ectopic pregnancy, unilateral tubal pregnancy}, volume = {21}, Number = {12}, pages = {1247-1252}, publisher = {Yasuj University Of Medical Sciences}, url = {http://armaghanj.yums.ac.ir/article-1-1383-en.html}, eprint = {http://armaghanj.yums.ac.ir/article-1-1383-en.pdf}, journal = {Armaghane Danesh}, issn = {1728-6506}, eissn = {1728-6514}, year = {2017} }